Clinical Trials on Digestive Disorders

Total 184601 results

Gynecologic Oncology Group
National Cancer Institute (NCI)

Completed

Zoledronate or Observation in Maintaining Bone Mineral Density in Patients Who Are Undergoing Surgery to Remove Both Ovaries

Osteoporosis | Ovarian Carcinoma | Hereditary Breast and Ovarian Cancer Syndrome

United States
COL George Peoples, MD, FACS
M.D. Anderson Cancer Center

Completed

Phase Ib Trial of Two Folate Binding Protein Peptide Vaccines (E39 and J65) in Breast and Ovarian Cancer Patients (J65)

Breast Cancer | Ovarian Cancer

United States
Enzyvant Therapeutics GmBH

Completed

Farber Disease Natural History Study

Farber Disease | Farber's Disease | Farber Lipogranulomatosis | Acid Ceramidase Deficiency | Ceramidase Deficiency | N-Laurylsphingosine Deacylase Deficiency | ASAH1 Mutation

United States, Egypt, Canada, Italy, Turkey, Argentina, Germany, India, Sweden
Georgetown University

Completed

Enhancing At-risk Latina Women's Use of Genetic Counseling for Hereditary Breast and Ovarian Cancer

Hereditary Breast and Ovarian Cancer

United States
National Cancer Institute (NCI)

Completed

AZD2281 Plus Carboplatin to Treat Breast and Ovarian Cancer

Breast Cancer | Ovarian Cancer

United States
University of Southern California
National Cancer Institute (NCI); National Institute for Biomedical Imaging...

Terminated

Ultrasound and Biomarker Tests in Predicting Cancer Aggressiveness in Tissue Samples of Patients With Bladder Cancer

Stage II Bladder Urothelial Carcinoma | Stage IV Bladder Urothelial Carcinoma | Stage III Bladder Urothelial Carcinoma | Bladder Papillary Urothelial Carcinoma | Stage 0a Bladder Urothelial Carcinoma | Stage 0is Bladder Urothelial Carcinoma | Stage I Bladder Cancer With Carcinoma In Situ | Stage...

United States
Case Comprehensive Cancer Center

Completed

Differentiation Therapy With Decitabine in Treating Patients With Myelodysplastic Syndrome

Myelodysplastic Syndromes | Thrombocytopenia | Chronic Myelomonocytic Leukemia | de Novo Myelodysplastic Syndromes | Refractory Anemia | Refractory Anemia With Excess Blasts | Refractory Cytopenia With Multilineage Dysplasia | Refractory Anemia With Ringed Sideroblasts

United States
Sidney Kimmel Comprehensive Cancer Center at Johns...
National Center for Complementary and Integrative Health (NCCIH)

Completed

A Fish Oil Supplement to Maintain Body Weight in Patients With Disease-Related Weight Loss

Cancer | Chronic Obstructive Pulmonary Disease | Rheumatoid Arthritis | Chronic Heart Failure | Cancer Cachexia

United States
Emory University

Completed

Identification and Referral of Women at Risk for Hereditary Breast/Ovarian Cancer

Hereditary Breast and Ovarian Cancer

United States
University Hospital, Clermont-Ferrand

Completed

Diffusion Tensor Imaging in Chronic Inflammatory Demyelinating Polyneuropathy (PIDC) (PIDC)

CIDP (Chronic Inflammatory Demyelinating Polyradiculoneuropathy) | CMT (Charcot Marie Tooth Disease)

France
Sanofi Pasteur, a Sanofi Company

Completed

Safety and Immunogenicity Study of a Diphtheria, Tetanus, Acellular Pertussis and Poliomyelitis Vaccine (REPEVAX) Followed by 2 Doses of a Diphtheria, Tetanus and Poliomyelitis Vaccine (REVAXIS) in Subjects of 40 Years of Age or Older

Pertussis | Tetanus | Diphtheria | Poliomyelitis

France, Germany
Hospices Civils de Lyon

Unknown

New Variants Involved in Taybi-Linder Syndrome (NewViTALS)

Genetic Syndrome | Taybi Linder Syndrome

France
M.D. Anderson Cancer Center

Completed

Attitudes About Childbearing And Fertility With Inherited Breast And Ovarian Cancer Syndromes (HBOC)

Breast Cancer | Ovarian Cancer

United States
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Pediatrics:Chlamydia, Sickle Cell Anemia and Stroke Risk - Ancillary to STOP II

Anemia, Sickle Cell | Blood Disease | Chlamydia Infections | Cerebrovascular Accident
Assistance Publique - Hôpitaux de Paris

Completed

Consequences of Antiangiogenic Factors Involved in Preeclampsia on Intra-uterine Growth Restricted Preterm Newborn (ANGIODYS)

Preterm Birth | Bronchopulmonary Dysplasia | Intra-uterine Growth Restriction | Maternal Preeclampsia

France
NewVac LLC
Janssen Pharmaceutica N.V., Belgium

Completed

Safety, Tolerability and Pharmacokinetics of Quisinostat, a Histone Deacetylase Inhibitor, in Combination With Chemotherapy

Epithelial Ovarian Cancer | Non-small Cell Lung Cancer

Russian Federation
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Infection and Cardiovascular Disease

Myocardial Infarction | Heart Diseases | Cardiovascular Diseases | Coronary Disease | Atherosclerosis | Helicobacter Infections | Cytomegalovirus Infections | Chlamydia Infections | Infection | Cerebrovascular Accident
Gynecologic Oncology Group
National Cancer Institute (NCI)

Completed

Radiation Therapy to the Abdomen Plus Docetaxel in Treating Patients With Recurrent or Persistent Advanced Ovarian, Peritoneal, or Fallopian Tube Cancer

Recurrent Ovarian Carcinoma | Fallopian Tube Carcinoma | Primary Peritoneal Carcinoma | Stage IV Ovarian Cancer | Stage III Ovarian Cancer

United States
Novartis Pharmaceuticals

Completed

Efficacy and Safety of Everolimus (RAD001) in Patients of All Ages With Subependymal Giant Cell Astrocytoma Associated With Tuberous Sclerosis Complex (TSC)(EXIST-1) (EXIST-1)

Tuberous Sclerosis | Subependymal Giant Cell Astrocytoma

United States, Belgium, Canada, Germany, Italy, Russian Federation, Netherlands, Poland, Australia, United Kingdom
King Edward Medical University

Unknown

Role of Mesenchymal Stem Cells in Fat Grafting

Lipodystrophy | Craniofacial Microsomia | Mixed Connective Tissue Disease | Romberg's Disease
NICHD Neonatal Research Network
National Center for Research Resources (NCRR)

Terminated

Minimal Breathing Support and Early Steroids to Prevent Chronic Lung Disease in Extremely Premature Infants (SAVE) (SAVE)

Respiratory Distress Syndrome | Bronchopulmonary Dysplasia | Infant, Small for Gestational Age | Infant, Premature | Infant, Low Birth Weight | Infant, Newborn

United States
Genzyme, a Sanofi Company

Completed

A Placebo-Controlled Study of Safety and Effectiveness of Myozyme (Alglucosidase Alfa) in Patients With Late-Onset Pompe Disease

Pompe Disease (Late-onset) | Glycogen Storage Disease Type II (GSD-II) | Acid Maltase Deficiency Disease | Glycogenosis 2

United States, France, Netherlands
Atlantic Health System

Terminated

High-Dose Erythropoietin in Extremely Premature Infants to Prevent/Attenuate Brain Injury: A Phase II Study

Brain Injury | Intraventricular Hemorrhage | Randomized Clinical Trial | Infant, Premature | Periventricular Leukomalacia | Neurodevelopmental Outcomes | Erythropoietin

United States
Boston Children's Hospital

Recruiting

Genetics of Epilepsy and Related Disorders

Epilepsy | Dravet Syndrome | Infantile Spasms | Epileptic Encephalopathy | Ohtahara Syndrome | Early Myoclonic Epileptic Encephalopathy | PCDH19-related Epilepsy and Related Conditions | KCNQ2-Related Epileptic Encephalopathy | Epilepsy of Infancy With Migrating Focal Seizures (Disorder)

United States
Fred Hutchinson Cancer Research Center/University...
National Cancer Institute (NCI)

Completed

Internet-Based Program With or Without Telephone-Based Problem-Solving Training in Helping Long-Term Survivors of Hematopoietic Stem Cell Transplant Cope With Late Complications

Depression | Fatigue | Primary Myelofibrosis | Stage I Multiple Myeloma | Stage II Multiple Myeloma | Stage III Multiple Myeloma | Chronic Myelomonocytic Leukemia | Recurrent Adult Acute Myeloid Leukemia | Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue | Nodal Marginal Zone... and other conditions

United States
City of Hope Medical Center
National Cancer Institute (NCI)

Completed

Vaccine Therapy in Preventing Cytomegalovirus Infection in Patients With Hematological Malignancies Undergoing Donor Stem Cell Transplant

Primary Myelofibrosis | Polycythemia Vera | Essential Thrombocythemia | Stage I Multiple Myeloma | Stage II Multiple Myeloma | Stage III Multiple Myeloma | Chronic Myelomonocytic Leukemia | Recurrent Adult Acute Myeloid Leukemia | Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid... and other conditions

United States
Case Comprehensive Cancer Center

Completed

High-Dose Busulfan and High-Dose Cyclophosphamide Followed By Donor Bone Marrow Transplant in Treating Patients With Leukemia, Myelodysplastic Syndrome, Multiple Myeloma, or Recurrent Hodgkin or Non-Hodgkin Lymphoma

Recurrent Adult Acute Myeloid Leukemia | Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue | Nodal Marginal Zone B-cell Lymphoma | Recurrent Adult Burkitt Lymphoma | Recurrent Adult Diffuse Large Cell Lymphoma | Recurrent Adult Diffuse Mixed Cell Lymphoma | Recurrent... and other conditions

United States
Henry Ford Health System
Abiomed Inc.

Enrolling by invitation

Can Escalation Reduce Acute Myocardial Infarction Mortality in Cardiogenic Shock (CERAMICS)

Acute Myocardial Infarction | Cardiogenic Shock | STEMI | NSTEMI - Non-ST Segment Elevation MI | STEMI - ST Elevation Myocardial Infarction | NSTEMI | Acute Myocardial Infarction With ST Elevation | Acute Myocardial Infarction of Right Ventricle (Disorder) | Acute Myocardial Infarction of Left Ventricle

United States
Novo Nordisk A/S

Completed

Investigation of Pharmacokinetics, Pharmacodynamics, Safety and Tolerability of Multiple Doses of Somapacitan in Subjects With Various Degrees of Impaired Renal Function Compared to Subjects With Normal Renal Function

Growth Hormone Disorder | Growth Hormone Deficiency in Children | Adult Growth Hormone Deficiency

Germany
University of the Punjab
Higher Education Commission (Pakistan); Centre of Excellence in Molecular Biology... and other collaborators

Recruiting

Efficacy of Preconditioned Adipose-Derived Stem Cells in Fat Grafting

Burn Scar | Craniofacial Microsomia | Romberg Disease | Post-Traumatic Scar (Disorder)

Pakistan
Fred Hutchinson Cancer Center
National Cancer Institute (NCI)

Completed

Alemtuzumab, Fludarabine Phosphate, and Total-Body Irradiation Followed by Cyclosporine and Mycophenolate Mofetil in Treating Patients Who Are Undergoing Donor Stem Cell Transplant for Hematologic Cancer

Chronic Myelomonocytic Leukemia | Recurrent Adult Acute Myeloid Leukemia | Juvenile Myelomonocytic Leukemia | Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue | Nodal Marginal Zone B-cell Lymphoma | Recurrent Adult Burkitt Lymphoma | Recurrent Adult Diffuse Large Cell... and other conditions

United States, Italy
Synaptrix Labs Inc.

Not yet recruiting

EMPOWER Early Feasibility Study: Non-invasive BCI to Control a Wheelchair for People With Paralysis

Paralysis | Amyotrophic Lateral Sclerosis | Spinal Cord Injuries | Neurologic Disorder | Cervical Spinal Cord Injury | Paralysis; Stroke | Tetraplegic; Paralysis | Quadriplegia/Tetraplegia

United States
Centre Hospitalier Saint Joseph Saint Luc de Lyon

Not yet recruiting

Assessment of the Effect of Restriction on Alimentary AGE in Progression of Chronic Kidney Disease (CKD AGE)

Kidney Failure, Chronic | Diet Habit | Chronic Kidney Disease stage3 | Chronic Kidney Disease Stage 3B | Chronic Kidney Disease, Stage 3 (Moderate) | Chronic Kidney Disease Stage 3A (Disorder)

France
Assistance Publique - Hôpitaux de Paris

Completed

Epidemiological Characteristics of COVID-19 in Patients With MS or NMO (COVISEP)

COVID-19 | Multiple Sclerosis | NMO Spectrum Disorder

France
City of Hope Medical Center
National Cancer Institute (NCI)

Completed

Infection Prophylaxis and Management in Treating Cytomegalovirus (CMV) Infection in Patients With Hematologic Malignancies Previously Treated With Donor Stem Cell Transplant

Primary Myelofibrosis | Polycythemia Vera | Essential Thrombocythemia | Stage I Multiple Myeloma | Stage II Multiple Myeloma | Stage III Multiple Myeloma | Chronic Myelomonocytic Leukemia | Recurrent Adult Acute Myeloid Leukemia | Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid... and other conditions

United States
Fred Hutchinson Cancer Center
Juno Therapeutics, Inc., a Bristol-Myers Squibb Company

Terminated

huJCAR014 CAR-T Cells in Treating Adult Patients With Relapsed or Refractory B-Cell Non-Hodgkin Lymphoma or Acute Lymphoblastic Leukemia

Refractory B-Cell Non-Hodgkin Lymphoma | Recurrent Adult Acute Lymphoblastic Leukemia | Recurrent B-Cell Non-Hodgkin Lymphoma | Recurrent Diffuse Large B-Cell Lymphoma | Recurrent Primary Mediastinal (Thymic) Large B-Cell Lymphoma | Refractory Adult Acute Lymphoblastic Leukemia | Refractory Diffuse... and other conditions

United States
National Cancer Institute (NCI)

Active, not recruiting

Veliparib and Temozolomide in Treating Patients With Acute Leukemia

Acute Myeloid Leukemia | Acute Myeloid Leukemia Arising From Previous Myelodysplastic Syndrome | Chronic Myelomonocytic Leukemia | Recurrent Adult Acute Myeloid Leukemia | Acute Lymphoblastic Leukemia | Secondary Acute Myeloid Leukemia | Recurrent Adult Acute Lymphoblastic Leukemia | Adult Acute... and other conditions

United States
National Cancer Institute (NCI)

Completed

Nivolumab With or Without Ipilimumab in Treating Younger Patients With Recurrent or Refractory Solid Tumors or Sarcomas

Recurrent Hodgkin Lymphoma | Refractory Hodgkin Lymphoma | Metastatic Melanoma | Stage III Cutaneous Melanoma AJCC v7 | Stage IV Cutaneous Melanoma AJCC v6 and v7 | Refractory Malignant Solid Neoplasm | Recurrent Melanoma | Recurrent Malignant Solid Neoplasm | Recurrent Neuroblastoma | Recurrent Non-Hodgkin... and other conditions

United States, Canada
Chinese PLA General Hospital

Unknown

Treatment of Relapsed and/or Chemotherapy Refractory B-cell Malignancy by Tandem CAR T Cells Targeting CD19 and CD22

Recurrent Adult Diffuse Large Cell Lymphoma | Recurrent Grade 1 Follicular Lymphoma | Recurrent Grade 2 Follicular Lymphoma | Recurrent Grade 3 Follicular Lymphoma | Recurrent Mantle Cell Lymphoma | Hematopoietic/Lymphoid Cancer | Adult Acute Lymphoblastic Leukemia in Remission | Prolymphocytic Leukemia and other conditions

China
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Recruiting

Association Between Health Care Provider (HCP)-Assessed ECOG Performance Status (PS) and Overall Survival, and Objectively Measure of Physical Activity (PA) Levels in Advance-cancer Patients"

Pancreatic Adenocarcinoma | Stage IV Colorectal Cancer AJCC v7 | Stage IVA Colorectal Cancer AJCC v7 | Stage IVB Colorectal Cancer AJCC v7 | Malignant Neoplasm | Recurrent Colorectal Carcinoma | Pancreatic Neuroendocrine Carcinoma | Malignant Head and Neck Neoplasm | Stage III Nasopharyngeal Carcinoma... and other conditions

United States
National Human Genome Research Institute (NHGRI)

Recruiting

A Natural History Study Seeks to Understand the Clinical, Genomic, Pharmacological, Laboratory, and Dietary Determinates of Pyrimidine and Purine Metabolism Disorders

Metabolic Disease | Purine-Pyrimidine Metabolism | AICDA, OMIM *605257, Immunodeficiency With Hyper-IgM, Type 2; HIGM2 | UNG, OMIM *191525, Hyper-IgM Syndrome 5 | NT5C3A<TAB>, OMIM *606224, Anemia, Hemolytic, Due to UMPH1 Deficiency | UMPS, OMIM *613891, Orotic Aciduria | DHODH, OMIM *126064,... and other conditions

United States
National Cancer Institute (NCI)

Completed

Cixutumumab in Treating Patients With Relapsed or Refractory Solid Tumors

Recurrent Neuroblastoma | Recurrent Osteosarcoma | Recurrent Childhood Rhabdomyosarcoma | Recurrent Adult Soft Tissue Sarcoma | Recurrent Wilms Tumor and Other Childhood Kidney Tumors | Previously Treated Childhood Rhabdomyosarcoma | Recurrent Childhood Soft Tissue Sarcoma | Adult Rhabdomyosarcoma | Neuroectodermal Tumor and other conditions

United States, Canada, Australia
Imperial College London

Not yet recruiting

SerUm and Plasma MicroRNAs in Malignant Ovarian gERm Cell Tumours (SUMMER)

Ovarian Neoplasms | Ovarian Cancer | Ovary Cancer | Germ Cell Tumor | Ovary Neoplasm | Germ Cell Cancer | Germ Cell Ovarian Cancer | Germ Cell Neoplasia
Verve Therapeutics, Inc.

Not yet recruiting

A Study of VERVE-102 in Patients With Familial Hypercholesterolemia or Premature Coronary Artery Disease

Heterozygous Familial Hypercholesterolemia | Premature Coronary Heart Disease
Universitätsklinikum Hamburg-Eppendorf

Recruiting

Digital Tool Enhancing GPs' Information Management for Patients With Multimorbidity - a Pilot Study (gp-multitool)

Coronary Disease | Diabetes Mellitus, Type 2 | Breast Neoplasms | Diabetes Mellitus, Type 1 | Pulmonary Disease, Chronic Obstructive | Asthma | Comorbidities and Coexisting Conditions

Germany
D'Or Institute for Research and Education
Oswaldo Cruz Foundation; Rio de Janeiro State Research Supporting Foundation... and other collaborators

Not yet recruiting

Extracellular Vesicles From Mesenchymal Cells in the Treatment of Acute Respiratory Failure

Pneumonia | Acute Respiratory Distress Syndrome (ARDS) | Severe Acute Respiratory Syndrome (SARS)

Brazil
Massachusetts General Hospital
Northwestern University; University of Florida; University of Minnesota; Henry... and other collaborators

Recruiting

ALS/MND Natural History Study Data Repository

ALS | Kennedy Disease | MND (Motor Neurone DIsease) | PLS | PMA - Progressive Muscular Atrophy | PBP - Progressive Bulbar Palsy

United States, Italy
Johns Hopkins University

Recruiting

Multi-parametric Biomarker Development to Predict Malignant Conversion in Patients With Neurofibromatosis Type 1

Neurofibromatosis 1 | Atypical Neurofibroma | Malignant Peripheral Nerve Sheath Tumor (MPNST) of Soft Tissue (Diagnosis)

United States
N.N. Petrov National Medical Research Center of...

Recruiting

Biobank and Register of Patients With Agresive Tumors for Translational and Analytical Research (REGATA)

Melanoma | Soft Tissue Sarcoma | Kidney Cancer | Colorectal Cancer | Prostate Cancer | Primary Brain Tumor | Malignant Solid Tumors

Russian Federation
Biotest

Recruiting

Efficacy and Safety of Trimodulin (BT588) in Subjects With CAP Including COVID-19 Pneumonia (TRICOVID)

COVID-19 | Pneumonia | Acute Respiratory Distress Syndrome | Community-acquired Pneumonia | Respiratory Infection | Bacterial Pneumonia | Viral Pneumonia | Fungal Pneumonia

Belgium, Brazil, Latvia, Germany, Lithuania, South Africa, Argentina, Austria, France, Hungary, Slovakia, Turkey, Portugal, Spain

Clinical Trials on Digestive Disorders

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