Clinical Trials on Digestive System Diseases

Total 386036 results

Peking Union Medical College Hospital

Unknown

Outcomes of Pelvic Surgery With and Without Anti-incontinence Procedure in Occult Stress Urinary Incontinence Patients (PTOS)

Pelvic Organ Prolapse | Stress Urinary Incontinence | Other Specified Urinary Incontinence

China
Lexicon Pharmaceuticals

Completed

An Open-label Study to Evaluate the Absorption, Metabolism, and Excretion of [14C]-Telotristat Etiprate in Males (LX1606-104)

Carcinoid Syndrome

United Kingdom
Mayo Clinic

Recruiting

NXP800 for the Treatment of Patients With Advanced or Metastatic Cholangiocarcinoma

Stage III Intrahepatic Cholangiocarcinoma AJCC v8 | Metastatic Cholangiocarcinoma | Refractory Cholangiocarcinoma | Stage III Hilar Cholangiocarcinoma AJCC v8 | Stage IV Hilar Cholangiocarcinoma AJCC v8 | Stage IV Intrahepatic Cholangiocarcinoma AJCC v8 | Advanced Cholangiocarcinoma

United States
Pediatric Brain Tumor Consortium
National Cancer Institute (NCI); American Lebanese Syrian Associated Charities...

Active, not recruiting

INCB7839 in Treating Children With Recurrent/Progressive High-Grade Gliomas

Glioblastoma Multiforme | Anaplastic Astrocytoma | Anaplastic Oligodendroglioma | DIPG | High-grade Astrocytoma NOS | CNS Primary Tumor, NOS (Malignant Glioma)

United States
Sidney Kimmel Cancer Center at Thomas Jefferson...

Completed

Durvalumab With or Without Metformin in Treating Participants With Head and Neck Squamous Cell Carcinoma

Head and Neck Squamous Cell Carcinoma | Oropharyngeal Squamous Cell Carcinoma | Oral Cavity Squamous Cell Carcinoma

United States
St. Louis University

Completed

A Prospective Assessment of Opioid Utilization Post-operatively in Sports Orthopaedic Surgeries (Opioids)

Postoperative Pain | Orthopedic Disorder | Opioid Use | Narcotic Use | Narcotic Abuse | Analgesic Drug Dependence | Opioids; Harmful Use | Opioid Abuse, Uncomplicated

United States
Assistance Publique - Hôpitaux de Paris
National Cancer Institute (NCI); Canceropôle Ile de France

Completed

Comprehensive Geriatric Assessment and Head and Neck Elderly Cancer Patients (EGéSOR)

Head and Neck Squamous Cell Carcinomas (HNSCCs)

France
Daiichi Sankyo, Inc.
Plexxikon

Terminated

A Phase 1b Open Label, Dose Escalation Study of PLX3397 in Combination With Vemurafenib in V600-mutated BRAF Melanoma

V600-mutated BRAF Unresectable Melanoma | V600-mutated BRAF Metastatic Melanoma | Stage III or Stage IV Metastatic Melanoma That Has Not Been Previously Treated With a Selective BRAF Inhibitor

United States, Germany, France
National Taiwan University Hospital

Unknown

Myeloid-derived Suppressor Cells (MDSCs) in OSCC Patients

Squamous Cell Carcinoma of the Oral Cavity

Taiwan
Sidney Kimmel Cancer Center at Thomas Jefferson...
Regeneron Pharmaceuticals; Prostate Cancer Foundation

Withdrawn

Stereotactic Body Radiation Therapy With REGN2810 and/or Ipilimumab Before Surgery in Treating Participants With Progressive Advanced or Oligometastatic Prostate Cancer

Stage III Prostate Cancer | Stage IV Prostate Cancer | Stage IVA Prostate Cancer | Stage IVB Prostate Cancer | Stage IIIA Prostate Cancer | Stage IIIB Prostate Cancer | Stage IIIC Prostate Cancer
Mayo Clinic
National Cancer Institute (NCI)

Completed

Vaccine Therapy and Resiquimod in Treating Patients With Stage II-IV Melanoma That Has Been Removed By Surgery

Recurrent Melanoma | Stage IV Melanoma | Stage IIIA Melanoma | Stage IIIB Melanoma | Stage IIIC Melanoma | Stage IIB Melanoma | Stage IIC Melanoma | Stage IIA Melanoma

United States
University Hospital, Caen

Unknown

TDM of Gentamicin and Vancomycin, in Neonates, Using Dried Blood Spot Sampling. (MIDOMEN)

Blood Sample for Routine Care | Term or Premature Newborns (28 to 44 Amenorrhea Weeks) | Gentamicin and/or Vancomycin

France
National Cancer Institute (NCI)

Completed

Temozolomide, Cixutumumab, and Combination Chemotherapy in Treating Patients With Metastatic Rhabdomyosarcoma

Stage IV Adult Soft Tissue Sarcoma | Adult Rhabdomyosarcoma | Metastatic Childhood Soft Tissue Sarcoma | Childhood Alveolar Rhabdomyosarcoma | Childhood Embryonal Rhabdomyosarcoma | Untreated Childhood Rhabdomyosarcoma

United States, Canada, Australia, New Zealand
Children's Oncology Group
National Cancer Institute (NCI)

Completed

Study of DNA in Blood Samples From Patients With Neuroblastoma

Recurrent Neuroblastoma | Disseminated Neuroblastoma | Localized Resectable Neuroblastoma | Localized Unresectable Neuroblastoma | Regional Neuroblastoma | Stage 4S Neuroblastoma

United States
Dilla University
African Population and Health Research Center; Addis Ababa University; International...

Completed

Dietary Diversity is Associated With Maternal Anemia and Key Prenatal Outcomes in Ethiopia

Anemia | Low Birth Weight | Pre-Term Birth | Still Birth

Ethiopia
Tata Memorial Hospital

Unknown

Study of 3-Dimensional Conformal Radiotherapy (3D-CRT) Versus Intensity Modulated Radiotherapy (IMRT) for Head and Neck Squamous Cell Carcinoma (HNSCC)

Squamous Cell Carcinoma of the Head and Neck

India
Center for Progressive Recovery, LLC
National Institute on Drug Abuse (NIDA); Yale University

Not yet recruiting

A Brief Negotiation Interview Chatbot to Improve Buprenorphine Engagement Among Justice-Involved Individuals (BNICHAT)

Criminal Behavior | Opioid Use Disorder, Moderate | Opioid Use Disorder, Severe
Karolinska Institutet
Swedish Council for Working Life and Social Research

Completed

A Problem Solving Based Intervention for Facilitating Return-to-work Among People Suffering From Common Mental Disorders (PROSA)

Depression | Anxiety Disorders | Adjustment Disorders | Common Mental Disorder

Sweden
University of New Mexico
Kaleo Inc.

Completed

Naloxone Auto-injector as a Universal Precaution for Patients With Opioid Substance Use Disorder

Opioid-Related Disorders | Opiate Antagonist Overdose

United States
Wake Forest University Health Sciences

Withdrawn

HOPE Trial hCG or Progesterone Effect on Recurrent Pregnancy Loss (HOPE)

Recurrent Pregnancy Loss Without Current Pregnancy
Brainsway

Completed

Prospective Multicenter Trial to Explore the Tolerability and Safety of the H-Coil Deep TMS in Combination With Serotonin Selective Reuptake Inhibitor(SSRI)

Major Depressive Disorder, Recurrent, Unspecified | Major Depressive Disorder, Single Episode, Unspecified

United States, Canada, Germany, Israel
Psychiatric Research Unit, Region Zealand, Denmark
The Clinic for Liaison Psychiatry in Koege, Department of Special Functions... and other collaborators

Completed

Outcome of Cognitive Behavioral Therapy for Patients With Severe Health Anxiety Treated in Group Only. A RCT. (CHAG)

Personality Disorders | Hypochondriasis | Illness Anxiety Disorder | Somatic Symptom Disorder | Severe Health Anxiety

Denmark
Sahlgrenska University Hospital, Sweden
Vastra Gotaland Region

Completed

Return to Work Among Cancer Survivors With Treatment-induced Survivorship Syndromes

Gynecologic Cancer | Prostate Cancer | Radiation Injuries | Radiation Toxicity | Radiotherapy Side Effect | Malignancy | Cancer Survivors | Radiation Syndrome

Sweden
National Institute of Mental Health (NIMH)

Completed

Detecting Risk of Suicide in a Pediatric Emergency Department

Adolescents | Suicide Prevention | Mental Disorder Diagnosed in Childhood

United States
National Institute of Mental Health (NIMH)

Terminated

A Magnetic Resonance Spectroscopic Examination of Children and Adolescents Taking Riluzole for Obsessive-Compulsive Disorder

Autism Spectrum Disorders | Childhood Obsessive-Compulsive Disorder

United States
NYU Langone Health
Yale University

Terminated

Kappa Opioid Receptor Imaging in Post-traumatic Stress Disorder (PTSD)

Trauma | Post-traumatic Stress Disorder (PTSD)

United States
Bagcilar Training and Research Hospital

Completed

Vascular Endothelial Growth Factor Levels at Hysteroscopic Biopsies Which Taken From Recurrent Pregnancy Loss

Recurrent Pregnancy Loss Without Current Pregnancy

Turkey
Dartmouth-Hitchcock Medical Center
National Institute of Mental Health (NIMH)

Completed

Cognitive Behavioral Treatment for Post-Traumatic Stress Disorder in People With Additional Serious Mental Illnesses

Post-Traumatic Stress Disorder

United States
Vanderbilt University

Completed

Effects of Risperidone and Olanzapine on Patients With Schizophrenia, Schizoaffective Disorder, Major Depression or Bipolar Disorder

Schizophrenia | Schizoaffective Disorder | Bipolar Disorder | Depressive Disorder, Major

United States
University of California, Los Angeles
University of Colorado, Denver; University of Pittsburgh; Virginia Commonwealth...

Recruiting

Children's Bipolar Network Treatment Trial I (CBN)

Bipolar Disorder | Child Mental Disorder | Bipolar I Disorder | Adolescent - Emotional Problem | Bipolar II Disorder | Other Specified Bipolar and Related Disorder | Mood Instability

United States
West Chester University of Pennsylvania
National Institute on Drug Abuse (NIDA)

Recruiting

Mindfulness-Based Relapse Prevention to Improve Medication Assisted Treatment Adherence and Drug-use Outcomes for Opioid Use Disorder

Opioid-use Disorder

United States
University of California, Davis
Yale University; University of Utah

Not yet recruiting

Feasibility of Pediatric Emergency Department-Initiated Treatment for Adolescents With Opioid Use Disorder (PEDsTREATOUD)

Opioid-use Disorder
Yale University
Harvard Medical School (HMS and HSDM); National Institute on Drug Abuse (NIDA) and other collaborators

Recruiting

Emergency Department-Initiated Buprenorphine Validation Network Trial

Opioid-use Disorder

United States
Boston Children's Hospital

Active, not recruiting

Genetic Contributions to Autism Spectrum Disorders

Autism Spectrum Disorder | Autism | Pervasive Developmental Disorder | Asperger's Syndrome

United States
NYU Langone Health
National Institute on Drug Abuse (NIDA)

Completed

Emergency Department Outcomes for Patients With Opioid Use Disorder

Opioid-use Disorder

United States
Q2i, LLC
National Institute on Drug Abuse (NIDA); University of Massachusetts, Worcester

Completed

Usability Testing for the Reward-based Technology to Improve OUD Treatment (OARSCM)

Contingency Management | Opioid-use Disorder | Medication for Opioid-use Disorder

United States
University of Tennessee
National Institutes of Health (NIH); National Center for Complementary and...

Completed

SMART Trial: Intrapersonal and Interpersonal Stigma Reduction

Substance Use Disorders | Opioid Use | Opioid-use Disorder | Stigma, Social

United States
NYU Langone Health
National Institute on Drug Abuse (NIDA)

Completed

Emergency Department Connection to Care With Buprenorphine for Opioid Use Disorder (ED-CONNECT)

Opioid-use Disorder

United States
New York State Psychiatric Institute
UCB Pharma

Completed

Levetiracetam for the Treatment of Alcohol Dependence and Anxiety

Alcoholism | Anxiety Disorders | Generalized Anxiety Disorder | Panic Disorder | Social Phobia

United States
University of Central Florida

Completed

Trauma Management Therapy for OEF and OIF Combat Veterans (TMT)

Combat Disorders | Post-Traumatic Stress Disorder

United States
Isaac Melamed
Bio Products Laboratory

Unknown

An Open-Label Study to Evaluate the Efficacy of High-Dose Gammaplex in Children on the Autism Spectrum

Autistic Disorder | Autism | Asperger's Disorder | Pervasive Developmental Disorder | PDD

United States
AstraZeneca

Completed

The Purpose of the Study is to Gain an In-depth Picture of the Patient Management and Prescription Behaviours

Schizophrenia | Major Depressive Disorders | Bipolar Disorders
University of Southern California

Not yet recruiting

Barbed Suture vs Non-Barbed Closure for Emergency Exploratory Laparotomy RCT

Emergency General Surgery | Trauma Abdomen | Laparotomy | Surgical Site Infections | Dehiscence Wound

United States
Duke University
National Institute on Alcohol Abuse and Alcoholism (NIAAA); Kilimanjaro Christian...

Recruiting

PRACT to Investigate Controlling Alcohol Related Harms in a Low-Income Setting; Emergency Department BIs in Tanzania (PRACT)

Trauma | Alcohol Use Disorder | Injury Traumatic

Tanzania
University of Washington
National Institute on Drug Abuse (NIDA)

Completed

Emergency Department Longitudinal Integrated Care (ED-LINC)

Opioid-use Disorder | Emergency Department

United States
Rutgers, The State University of New Jersey
National Institute on Drug Abuse (NIDA)

Completed

Persistence Targeted Smoking Cessation in Serious Mental Illness (SMI) (PTSC-S)

Schizophrenia | Schizoaffective Disorder | Tobacco Use | Tobacco Smoking | Tobacco Use Disorder | Tobacco Use Cessation

United States
Groupe Oncologie Radiotherapie Tete et Cou
Gustave Roussy, Cancer Campus, Grand Paris

Completed

Phase II Trial of Carboplatin, 5-FU and Cetuximab in Elderly Fit (no Frailty) Patients With Recurrent/Metastatic HNSCC (ELANFIT)

Metastatic or Recurrent Head and Neck Squamous Cell Cancer

France
Charles Taylor
Laureate Institute for Brain Research, Inc.

Suspended

Amplification of Positivity for Alcohol Use Disorder Co-Occurring With Anxiety or Depression

Substance-Related Disorders | Depression | Alcohol Drinking | Drinking Behavior | Alcoholism | Alcohol-Related Disorders | Anxiety | Mental Disorder

United States
Karolinska Institutet
Region Stockholm

Completed

Effectiveness of ICBT for Severe Health Anxiety in Clinical Psychiatry.

Hypochondriasis | Health Anxiety | Illness Anxiety Disorder | Somatic Symptom Disorder | Severe Health Anxiety | Hypochondriacal Disorder, Unspecified

Sweden
Dartmouth-Hitchcock Medical Center
National Institute on Drug Abuse (NIDA); Columbia University; University of Vermont and other collaborators

Completed

Cannabis and Schizophrenia: Self-Medication and Agonist Treatment

Schizophrenia | Schizoaffective Disorder | Dual Diagnosis | Psychotic Disorder | Cannabis Use Disorder

United States

Clinical Trials on Digestive System Diseases

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