Clinical Trials on Drug Resistance

Total 8127 results

Repros Therapeutics Inc.

Completed

Assessment of Drug-Drug Interactions of Androxal With Cytochrome P450 Isoenyzmes in Healthy Males

Drug-drug Interaction

United States
AstraZeneca

Completed

Evaluation of the Drug-drug Interaction Between Ticagrelor and Venlafaxine When Taken Together in Healthy Volunteers

Drug Drug Interaction

United States, Sweden
Centre Hospitalier Universitaire, Amiens

Recruiting

Optimized and Personalized Trans-cranial Brain Stimulation in Partial Refractory Epilepsies (PerEpi2)

Epilepsy | Children | tDCS | Transcranial Electric Stimulation | Pharmacoresistant | HR EEG

France
University of Arizona
Virginia Polytechnic Institute and State University; Arizona State University

Enrolling by invitation

Electrochemical and Electrophysiological Study

Cognition | Medically Intractable Epilepsy

United States
Monteris Medical

Terminated

Feasibility Study on LITT for Medical Refractory Epilepsy

Epilepsy

United States
UCB Biopharma S.P.R.L.
PRA Health Sciences

Completed

A Study of UCB0942 in Adult Patients With Highly Drug-resistant Focal Epilepsy

Highly Drug-resistant Focal Epilepsy

Belgium, Bulgaria, Germany, Hungary, Netherlands, Spain
Asceneuron S.A.

Recruiting

Drug-Drug Interaction of ASN51 With Fluvoxamine, Itraconazole and Paroxetine in Healthy Subjects

Drug Drug Interaction

Netherlands
Daewoong Pharmaceutical Co. LTD.

Recruiting

Drug-drug Interactions Between DWC202313 and DWC202314 in Healthy Subjects

Drug Drug Interaction

Korea, Republic of
Indiana University
National Institute of General Medical Sciences (NIGMS)

Recruiting

Interaction of CYP2B6 Genotype and Efavirenz With Methadone and Tizanidine PK

Drug-Drug Interaction

United States
VistaGen Therapeutics, Inc.
Parexel

Recruiting

AV-101 Alone and in Combination With Probenecid in Healthy Subjects

Drug Drug Interaction

United States
CMP Development, LLC

Completed

Drug-drug Interaction (DDI) Study of Spironolactone (Perpetrator) and Digoxin (Substrate Drug)

Drug Drug Interaction

India
Pyramid Biosciences

Completed

A Study of PBI-200 With Ritonavir or Cobicistat in Healthy Volunteers

Drug-drug Interaction

United States
Shanghai Pharmaceuticals Holding Co., Ltd

Completed

Drug-drug Interaction Study of SPH3127

Drug Drug Interaction

China
Blade Therapeutics

Completed

Drug-Drug Interaction (DDI) Study in Healthy Volunteers

Drug Drug Interaction

Australia
Antios Therapeutics, Inc

Completed

A Drug-Drug Interaction Study Between ATI-2173 and Midazolam or Clarithromycin in Healthy Subjects

Drug Drug Interaction

Canada
University Hospital, Basel, Switzerland

Completed

Inhibition Metamizole 2020

Drug-drug Interaction

Switzerland
Genfit

Completed

Study to Investigate the Potential Drug-Drug Interaction Between Elafibranor and Indomethacin

Drug-drug Interaction

France
Qure Healthcare, LLC
Aegis Sciences Corporation

Completed

DDI Effectiveness and Clinical Awareness (DECART)

Drug-Drug Interactions

United States
Santhera Pharmaceuticals

Completed

A Study to Assess the Potential for Pre-systemic Inhibition of CYP3A by Idebenone Using Midazolam as a Substrate

Drug-Drug Interaction

France
Guangdong Raynovent Biotech Co., Ltd

Completed

Drug-durg Interaction of Leritrelvir(RAY1216) With Midazolam, Omeprazole, Rosuvastatin, Verapamil, and Rifampin

Drug Drug Interaction

China
Italfarmaco

Completed

The Potential of Givinostat as DDI Victim in Co-administration P-gp Inhibitor (Part 2)

Drug Drug Interaction

Portugal
Guangdong Raynovent Biotech Co., Ltd

Completed

Drug-durg Interaction of ZSP1273 With Digoxin, Rosuvastatin,Itraconazole and Probenecid

Drug Drug Interaction

China
Sumitomo Pharma America, Inc.

Completed

A Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Drug Interaction Potential of Napabucasin in Healthy Volunteers

Drug-drug Interactions

United States
Italfarmaco

Completed

Givinostat and Metabolites Pharmacokinetics in Urine and Plasma (Part 3)

Drug Drug Interaction

Portugal
Daewoong Pharmaceutical Co. LTD.

Completed

Drug-drug Interactions Between DWP14012 and Aspirin in Healthy Subjects

Drug Drug Interaction

Korea, Republic of
Chong Kun Dang Pharmaceutical

Completed

CKD-506 Drug-Drug Interaction Study in Healthy Male Subjects

Drug Drug Interaction

Netherlands
HUYABIO International, LLC.

Completed

Drug-Drug Interaction Study of HBI-3000 and Paroxetine in Healthy Adult Male and Female Subjects

Drug-drug Interaction

United States, Australia
Haisco Pharmaceutical Group Co., Ltd.

Completed

Drug-drug Interaction Between Ciprofol and Mefanamic Acid or Valproate

Drug Drug Interaction

China
Otsuka Pharmaceutical Development & Commercialization...

Completed

A Phase 1, Drug Interaction Study Between AVP-786 and Paroxetine and Between AVP-786 and Duloxetine in Healthy Subjects

Drug-drug Interaction

Australia
Guangdong Raynovent Biotech Co., Ltd

Completed

Study to Investigate the Potential Drug-Drug Interaction Between ZSP1273 and Oseltamivir

Drug-drug Interaction

China
University of California, San Francisco

Completed

Drug-Drug Interaction Between Rifampin and Fluvastatin

Drug-drug Interaction

United States
Hutchison Medipharma Limited
Covance

Completed

Fruquintinib CYP3A Inhibitor and Inducer Study

Drug Drug Interaction

United States
SymBio Pharmaceuticals

Completed

Drug-Drug Interaction Study of Intravenous Administration of SyB V-1901 and Cyclosporine in Japanese Healthy Subjects

Drug Drug Interaction

Japan
Biosplice Therapeutics, Inc.

Completed

Drug-Drug Interaction Study of Lorecivivint and Triamcinolone Acetonide in Healthy Volunteers

Drug-Drug Interaction

United States
Seagen Inc.

Completed

A Drug-Drug Interaction Study in Healthy Volunteers of the Effects of Tucatinib

Drug-drug Interaction

United States
Seagen Inc.

Completed

A Drug-Drug Interaction Study in Healthy Volunteers of the Effects of Tucatinib on Metformin

Drug-drug Interaction

United States
Lexicon Pharmaceuticals

Completed

A Phase 1 Study to Evaluate the Effects of Omeprazole and Famotidine on the Absorption of Telotristat Ethyl in Healthy Subjects

Drug-drug Interaction

United States
Swedish Orphan Biovitrum
Parexel

Completed

A Study to Investigate the Potential Influence of Nitisinone on the Metabolism and the Transport of Other Drugs in Healthy Volunteers

Drug Drug Interaction

Germany
Genovate-NaviFUS (Australia) Pty Ltd.
Genovate Biotechnology Co., Ltd.,; NaviFUS Corporation

Recruiting

Evaluation of the NaviFUS System in Drug Resistant Epilepsy

Drug Resistant Epilepsy | Epilepsy, Temporal Lobe

Australia
Brain Sentinel

Not yet recruiting

Impact of SPEAC® System Data on Therapeutic Decisions Related to Convulsive Seizure Patient's Refractory to AEDs

Epilepsy Intractable
Louisiana State University Health Sciences Center...

Unknown

Pilot Trial to Evaluate The Effect of Oral Methylprednisolone on Seizure Frequency in Children With Epilepsy

Intractable Epilepsy | Convulsive Seizures

United States
Otsuka Pharmaceutical Development & Commercialization...

Completed

A Trial to Evaluate OPC 67683 in Participants With Pulmonary Sputum Culture-positive, Multidrug-resistant Tuberculosis (TB)

Tuberculosis, Pulmonary | Extensively Drug-Resistant Tuberculosis | Tuberculosis, Multidrug Resistant

Korea, Republic of, China, United States, Egypt, Estonia, Japan, Latvia, Peru, Philippines
Assistance Publique - Hôpitaux de Paris

Not yet recruiting

Cartography of Social Cognition Network and Their Alterations in Patients With Epilepsy (SocrAlt)

Epilepsy | Drug Resistant Epilepsy
Armed Forces Research Institute of Medical Sciences...
National Center for Parasitology, Entomology, and Malaria Control (CNM); Naval...

Recruiting

Drug Combinations of Atovaquone-Proguanil (AP) With ACT (APACT)

Plasmodium Falciparum Malaria (Drug Resistant)

Cambodia
The Epilepsy Research Program of the Ontario Brain...
University Health Network, Toronto; University of Toronto; London Health Sciences... and other collaborators

Terminated

Cannabis Extract in Refractory Epilepsy Study (CERES)

Drug Resistant Epilepsy

Canada
Johns Hopkins University
National Institute of Allergy and Infectious Diseases (NIAID); University of... and other collaborators

Recruiting

Bring BPaL2Me Trial Comparing Nurse-Led RR-TB Treatment to Physician-Led RR-TB Treatment

Drug Resistant Tuberculosis

South Africa
Idorsia Pharmaceuticals Ltd.

Completed

Pharmacokinetics of Omeprazole and Midazolam When Co-administered With ACT-1014-6470

Healthy | Drug Drug Interaction

Czechia
Theravance Biopharma

Completed

Drug-Drug Interaction (DDI) Study for TD-9855

Drug Drug Interaction (DDI)

United States
Bristol-Myers Squibb

Completed

A Phase 1 Drug-drug Interaction Study in Healthy Volunteers (DDI)

Drug-drug Interaction Study

United States
Jemincare

Completed

A DDI Study of JMKX000623 and Metformin Hydrochloride

Healthy | Drug-Drug Interaction

China

Clinical Trials on Drug Resistance

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Rare Diseases

Drug Interventions

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