Clinical Trials on Drug Metabolism, Poor, CYP2D6-RELATED in Japan

Total 531 results

Eisai Co., Ltd.

Active, not recruiting

A Study of Equfina® on the Incidences of Adverse Drug Reactions in Participants With Parkinson's Disease (Including Participants With Hepatic Impairment)

Parkinson Disease

Japan
Nihon Pharmaceutical Co., Ltd

Completed

Phase III Clinical Trial of NPB-01 in Patients With Stevens-Johnson Syndrome/ Toxic Epidermal Necrolysis Unresponsive to Corticosteroids.

Stevens-Johnson Syndrome | Toxic Epidermal Necrolysis

Japan
Andreas Benesic, MD
MetaHeps GmbH

Unknown

Cells of Monocytic Origin as Surrogate Markers for Individual Drug Effects and Hepatotoxicity

Adverse Reaction to Drug | Drug-induced Disorder of Liver

Hong Kong, Australia, Germany, Japan, Korea, Republic of
Osaka Saiseikai Nakatsu Hospital

Completed

Nippon Ultra-Rapid Insulin and Diabetic Complication Evaluation-Study (NICE-Study)

Diabetes Mellitus

Japan
Eli Lilly and Company

Completed

A Study of Nasal Glucagon (LY900018) in Japanese Participants With Diabetes Mellitus

Diabetes Mellitus

Japan
Bayer

Completed

Special Drug Use Investigation of Glucobay OD

Diabetes Mellitus

Japan
Hiroshima University
NewBio Enterprise Co., ltd.

Completed

Effect of the Extract of the Flour Fermented With Bacillus Subtilis Var Natto DC-15 on Postprandial Glucose

Prediabetes

Japan
Hiroshima University
KAWAMOTO FOODS CO., LTD.

Completed

Effect of Coadministration of Ume Paste (Prunus Mume) and Ginger Powder

Prediabetes

Japan
Eli Lilly and Company

Completed

Observational Study in Japanese Type 2 Diabetes Patients (INSIGHTS)

Diabetes Mellitus, Type 2

Japan
Sanofi

Completed

Efficacy and Safety of Insulin Glulisine in Type 2 Diabetes Mellitus

Diabetes Mellitus, Type 2

Japan
National Cerebral and Cardiovascular Center

Recruiting

Teneligliptin on the Progressive Left Ventricular Diastolic Dysfunction With Type 2 Diabetes Mellitus Study (TOPLEVEL)

Diabetes Mellitus, Type 2

Japan
Jikei University School of Medicine
Novo Nordisk A/S

Unknown

Jikei Optimal Insulin Therapy in Type 2 Diabetes

Diabetes Mellitus, Type 2

Japan
Novo Nordisk A/S

Completed

A Research Study of a New Medicine NNC0519-0130 in Japanese and Non-Japanese Men

Diabetes Mellitus, Type 2

Japan
Boehringer Ingelheim
Eli Lilly and Company

Completed

A Long-term Study on the Side Effects of TRADIANCE in Japanese Patients With Type 2 Diabetes

Diabetes Mellitus, Type 2

Japan
Takeda

Completed

Efficacy and Safety of Alogliptin in Participants With Type 2 Diabetes in Japan

Diabetes Mellitus, Type 2

Japan
Novo Nordisk A/S

Completed

Safety and Effect of Biphasic Insulin Aspart 50 in Patients With Type 2 Diabetes Mellitus.

Diabetes Mellitus, Type 2 | Diabetes

Japan
Novo Nordisk A/S

Completed

Insulin Profile of Biphasic Insulin Aspart 70 to That of Biphasic Insulin Aspart 30 in Healthy Volunteers

Diabetes Mellitus, Type 2 | Diabetes

Japan
Novo Nordisk A/S

Completed

Effect of Liraglutide in Combination With Sulfonylurea (SU) on Blood Glucose Control in Subjects With Type 2 Diabetes

Diabetes Mellitus, Type 2 | Diabetes

Japan
Novo Nordisk A/S

Completed

Efficacy and Safety of Insulin Detemir in Type 2 Diabetes Inadequately Controlled on OHA Therapy Alone

Diabetes Mellitus, Type 2 | Diabetes

Japan
Sanofi

Completed

GLP-1 Receptor Agonist Lixisenatide in Patients With Type 2 Diabetes for Glycemic Control and Safety Evaluation in Monotherapy (GETGOAL-MONO Japan LTS) (GETGOAL-MONO)

Diabetes Mellitus, Type 2

Japan
Japan Early Diabetes Intervention Study Group

Unknown

Japan Early Diabetes Intervention Study (JEDIS)

Diabetes Mellitus

Japan
Ministry of Health, Labour and Welfare, Japan
Bayer; Japan Heart Foundation

Unknown

Japanese Primary Prevention Project With Aspirin

Hypertension | Diabetes Mellitus | Hyperlipidemia

Japan
Kansai Electric Power Hospital
Saiseikai Noe Hospital Osaka

Completed

Dietary Impacts on Glucose-lowering Effects of Sitagliptin in Type 2 Diabetes (DIET)

Diabetes Mellitus, Type 2

Japan
Translational Research Center for Medical Innovation...
Astellas Pharma Inc; Osaka Saiseikai Nakatsu Hospital

Completed

Investigation for Clinical Efficacy and Safety of Ipragliflozin 50mg and 100mg on Type II Diabetes (HARUKAS)

Diabetes Mellitus, Type 2

Japan
Novo Nordisk A/S

Completed

Evaluating the Safety and Effectiveness of Liraglutide in Subjects With Type 2 Diabetes

Diabetes Mellitus, Type 2 | Diabetes

Japan
Novo Nordisk A/S

Completed

Effect of Liraglutide on Blood Glucose Control in Subjects With Type 2 Diabetes

Diabetes Mellitus, Type 2 | Diabetes

Japan
Novo Nordisk A/S

Completed

Comparison of Biphasic Insulin Aspart Produced by the NN2000 Process to Current Process to in Type 2 Diabetes

Diabetes Mellitus, Type 2 | Diabetes

Japan
Novo Nordisk A/S

Completed

Bioequivalence of Two Formulations of Biphasic Insulin Aspart 50 in Healthy Japanese Subjects

Diabetes Mellitus, Type 2 | Diabetes

Japan
Novo Nordisk A/S

Completed

Effect of Liraglutide on Blood Glucose Control in Japanese Subjects With Type 2 Diabetes

Diabetes Mellitus, Type 2 | Diabetes

Japan
Novo Nordisk A/S

Completed

Safety and Tolerability of Liraglutide in Japanese Subjects With Type 2 Diabetes

Diabetes Mellitus, Type 2 | Diabetes

Japan
Novo Nordisk A/S

Completed

Efficacy and Safety of Three Times a Day BIAsp-70 Compared to Two Times a Day BIAsp-30 in Subjects With Type 2 Diabetes

Diabetes Mellitus, Type 2 | Diabetes

Japan
Novo Nordisk A/S

Completed

Pharmacokinetics and Pharmacodynamics of Biphasic Insulin Aspart 30 and 50 in Subjects With Type 2 Diabetes

Diabetes Mellitus, Type 2 | Diabetes

Japan
Novo Nordisk A/S

Completed

Safety and Efficacy of Insulin Aspart in Type 2 Diabetes

Diabetes Mellitus, Type 2 | Diabetes

Japan
Novartis

Completed

Long-Term Safety Study of Vildagliptin in Patients With Type 2 Diabetes

Diabetes Mellitus, Type 2

Japan
Novartis

Completed

To Compare the Efficacy and Safey of Vildagliptin Compared to Voglibose in Patients With Type 2 Diabetes

Diabetes Mellitus, Type 2

Japan
Novartis

Completed

To Assess the Efficacy and Safety of Vildagliptin as Add-on Therapy to Sulfonylurea in Patients With Type 2 Diabetes Inadequately Controlled With Sulfonylurea Monotherapy

Diabetes Mellitus, Type 2

Japan
Novartis

Completed

A Study To Compare the Effect of Vildagliptin Compared to Placebo in Patients With Type 2 Diabetes

Diabetes Mellitus, Type 2

Japan
Novo Nordisk A/S

Completed

A Research Study Looking at How Oral Semaglutide Works in People With Type 2 Diabetes in Japan, as Part of Local Clinical Practice (PIONEER REAL)

Diabetes Mellitus, Type 2

Japan
Novo Nordisk A/S

Completed

Safety and Efficacy of Biphasic Insulin Aspart 50 in Subjects With Type 2 Diabetes

Diabetes Mellitus, Type 2 | Diabetes

Japan
Novo Nordisk A/S

Completed

Safety and Tolerability of Liraglutide in Healthy Japanese Male Volunteers

Diabetes Mellitus, Type 2 | Diabetes

Japan
Novo Nordisk A/S

Completed

Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Liraglutide in Healthy Japanese Volunteers

Diabetes Mellitus, Type 2 | Diabetes

Japan
Janssen Pharmaceutical K.K.

Completed

Safety, Pharmacokinetics, and Pharmacodynamics Study of Single Dose of CNTO 3649 in Healthy Adult Men and Multiple Doses of CNTO 3649 in Participants With Type 2 Diabetes Mellitus

Healthy | Diabetes Mellitus, Type 2

Japan
Novartis

Completed

Long Term Safety of Vildagliptin (100mg qd) In Patients With Type 2 Diabetes

Diabetes Mellitus, Type 2

Japan
Novo Nordisk A/S

Completed

A Trial to Assess the Pharmacokinetics, Pharmacodynamics, and the Safety and Tolerability of Semaglutide in Healthy Male Japanese and Caucasian Subjects

Healthy | Diabetes Mellitus, Type 2 | Diabetes

Japan
Japan Foundation for the Promotion of International...
Japan Diabetes Foundation

Unknown

The Japan Diabetes Optimal Integrated Treatment Study for 3 Major Risk Factors of Cardiovascular Diseases (J-DOIT3)

Cardiovascular Diseases | Diabetes Mellitus, Type 2

Japan
Novo Nordisk A/S

Completed

A Trial to Assess the Pharmacokinetics, Pharmacodynamics, Safety and Tolerability of Oral Semaglutide in Healthy Male Japanese and Caucasian Subjects

Healthy | Diabetes Mellitus, Type 2 | Diabetes

Japan
Hiroshima University
Agricultural Producers' Cooperative Corporation Shinpo-en

Completed

Effects of Blueberry Dry Powder on Glycemic Status in Subjects With Prediabetes

Prediabetes

Japan
Boehringer Ingelheim
Eli Lilly and Company

Completed

Daily Use of JARDIANCE® Tablets in Japanese Elderly Patients With Type 2 Diabetes Mellitus

Diabetes Mellitus, Type 2

Japan
Boehringer Ingelheim

Completed

Clinical Characteristics and Practice Patterns of Type 2 Diabetes Mellitus Patients Treated With OADs in Japan: Analysis of Medical and Health Care Database of the MDV

Diabetes Mellitus, Type 2

Japan
AstraZeneca

Completed

Phase I Multiple-Ascending Dose (Japan) (MAD)

Diabetes Mellitus, Type 2

Japan

3

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