Clinical Trials on Drug Toxicity

Total 3602 results

Anhui Provincial Hospital

Recruiting

Neoadjuvant Chemoradiotherapy Combined With Camrelizumab and Nimotuzumab for Esophageal Squamous Cell Carcinoma

Toxicity, Drug

China
Vejle Hospital
Region of Southern Denmark

Recruiting

Prevention of Chest Pain in Chemo-treated Cancer Patients (CATCH)

Chest Pain | Acute Coronary Syndrome | Cardiotoxicity | Chemotherapeutic Toxicity | Coronary Artery Calcification | Solid Carcinoma | 5-Fluorouracil Toxicity

Denmark
Centre Hospitalier Universitaire Saint Pierre

Recruiting

Cardiovascular Effects of Intrathecal Hyperbaric Prilocaine or Bupivacaine in Surgery Under Spinal Anesthesia

Spinal Anesthesia | Cardiac Toxicity

Belgium
M.D. Anderson Cancer Center
Alere San Diego

Unknown

Effectiveness of Using Biomarkers to Detect and Identify Cardiotoxicity and Describe Treatment (PREDICT)

Unspecified Adult Solid Tumor, Protocol Specific | Cardiac Toxicity

United States
DTU National Food Institute
University Hospital Bispebjerg and Frederiksberg

Recruiting

Jodkids: a Study of Iodine Intake Among Children Aged 2-10 Years

Diet Habit | Iodine Deficiency | Iodine Toxicity

Denmark
Neolys
Centre Francois Baclesse; Centre Hospitalier Universitaire de Caen

Not yet recruiting

Integrative Molecular Analysis of Individual Radiosensitivity in Pediatric Oncology (FOCUSO)

Pediatric Cancer | Radiation Toxicity | Radiosensitivity
Istanbul University - Cerrahpasa (IUC)

Recruiting

Effectiveness of Mobile Based Monitoring System in the Management of Chemotherapy-Related Symptoms

Cancer | Mobile Applications | Chemotherapeutic Toxicity

Turkey
Huashan Hospital
Children's Hospital of Fudan University; Shanghai Children's Hospital; Shanghai... and other collaborators

Recruiting

Neurodevelopment of Infants Exposed to General Anesthesia: a Multi-center Investigation (GENIUS)

Infant | Neurodevelopment | General Anesthetics Toxicity

China
Nanjing Medical University

Completed

Immune Checkpoint Inhibitors(ICPis)-Induced Endocrine Immune-related Adverse Events (irAEs)

Immune Checkpoint Inhibitor | Endocrine Toxicity

China
Fondazione Policlinico Universitario Agostino Gemelli...

Completed

Ropivacaine Plasma Concentration With or Without Epinephrine for Posterior Quadratus Lumborum Block

Anesthesia, Local | Local Anesthetic Systemic Toxicity

Italy
Fundação Bahiana de Infectologia
Hospital de Clinicas de Porto Alegre; Universidade Federal do Rio Grande do... and other collaborators

Recruiting

Dolutegravir and Clinical Outcomes Among ART-recipients in Brazil (CODE)

HIV Infections | Clinical Outcomes | Adverse Drug Event | Effect of Drugs

Brazil
Children's Oncology Group
National Cancer Institute (NCI)

Completed

Enalapril in Treating Heart Damage Patients Who Received Anthracycline Chemotherapy for Childhood Cancer

Unspecified Childhood Solid Tumor, Protocol Specific | Cardiac Toxicity

United States, Canada, Switzerland
National Cancer Institute (NCI)

Completed

Oblimersen Plus Combination Chemotherapy and Dexrazoxane in Treating Children and Adolescents With Relapsed or Refractory Solid Tumors

Unspecified Childhood Solid Tumor, Protocol Specific | Cardiac Toxicity

United States
Air Force Military Medical University, China

Completed

Association Between Telomere Length and Cardiac Dysfunction

Acute Leukemia | Childhood Cancer | Cardiac Toxicity

China
Nicolaus Copernicus University

Completed

Selected Lysosomal Enzyme Activities and the Oxidant-antioxidant Balance in Hyperbaric Oxygen Condition.

Oxidative Stress | Oxygen Toxicity | Antioxidants | Hyperbaric Oxygenation

Poland
Odense University Hospital

Recruiting

COr Loco-regional Advanced Lung Cancer Treated With Chemo-radiotherapy (COLA) (COLA)

Radiation Toxicity | Cardiac Disease | Cardiac Toxicity | Lung Cancer Stage III | Lung Cancer Stage II

Denmark
Duke University
University of California, San Francisco

Completed

Machine Learning to Predict Acute Care During Cancer Therapy (Chemo-SHIELD)

Chemotherapeutic Toxicity

United States
Globe Biotech Limited

Completed

A Randomized, Double-blinded, Active Controlled Crossover Clinical Trial to Investigate PK, PD and Safety of GBPD002

Natural Blood and Blood Product Toxicity

Bangladesh
University of California, Los Angeles

Completed

NAC Prevents Toxicity of Teeth Bleaching

Removal of Toxicity From Dental Bleaching
KU Leuven

Completed

Effect of Increased Protein Intake on Colonic Metabolism

Protein Fermentation | Toxicity in the Colon

Belgium
Masonic Cancer Center, University of Minnesota

Completed

EMR Chemotoxicity Risk Calculator To Decrease Chemotherapy Toxicity

Metastatic Solid Tumor | Chemotherapeutic Toxicity | Oncology

United States
Namik Kemal University

Active, not recruiting

G8, VES-13 and CARG Scores in Predicting Chemotherapy Toxicity in Geriatric Cancer Patients

Predicting Chemotherapy Related Toxicity in Elderly Patients

Turkey
Cedars-Sinai Medical Center
Jarrow Formulas Inc

Not yet recruiting

SAMe in Prevention of Oxaliplatin-associated Liver Injury

Colorectal Cancer | Liver Metastases | Liver Metastasis Colon Cancer | Liver Injury | Sinusoidal Obstruction Syndrome | 5-Fluorouracil Toxicity | Liver Toxicity, Chemically-Induced

United States
Sunnybrook Health Sciences Centre
University Health Network, Toronto

Completed

Effect of an Automated Paging System on Response to Critical Laboratory Values

Drug Drug Interactions | Critical Laboratory Values | Drug Laboratory Interactions

Canada
University of Southern California

Recruiting

Impact of Rifabutin on the Pharmacokinetics of Elexacaftor/Tezacaftor/Ivacaftor

Drug Drug Interaction

United States
Daewoong Pharmaceutical Co. LTD.

Active, not recruiting

Phase 1 Clinical Trial to Evaluate the Effect of DWP14012 on the Pharmacokinetics of DWC202201 in Healthy Subjects

Drug Drug Interaction

Korea, Republic of
Daewoong Pharmaceutical Co. LTD.

Enrolling by invitation

Drug-drug Interactions Between DWC202211 and DWC202212 in Healthy Subjects (DWJ1610)

Drug-drug Interaction

Korea, Republic of
Daewoong Pharmaceutical Co. LTD.

Completed

Drug-drug Interactions Between DWP14012 and DWC202202 in Healthy Subjects

Drug Drug Interaction

Korea, Republic of
Italfarmaco

Completed

Perpetrator DDI Potential of Givinostat as Inhibitor and Inducer of CYP3A and P-gp Activity

Drug-Drug Interaction

Portugal
Aurinia Pharmaceuticals Inc.

Completed

Drug-Drug Interaction Study to Investigate Effects of Voclosporin on Pharmacokinetics of Simvastatin (Statin-DDI)

Drug-drug Interaction

United States
Blade Therapeutics

Completed

Dedicated Drug-Drug Interaction (DDI) Study in Healthy Volunteers

Drug Drug Interaction

United States
Daewoong Pharmaceutical Co. LTD.

Completed

Pharmacokinetic Interaction Between DWP14012 and DWC202005 in Healthy Volunteers

Drug-drug Interaction

Australia
Nanjing Yoko Biomedical Co., Ltd.

Completed

Drug-drug Interaction Study Between Edaravone and 2-Aminoethanesulfonic Acid in Compound Edaravone Injection

Drug-drug Interaction

China
Repros Therapeutics Inc.

Completed

Assessment of Drug-Drug Interactions of Androxal With Cytochrome P450 Isoenyzmes in Healthy Males

Drug-drug Interaction

United States
AstraZeneca

Completed

Evaluation of the Drug-drug Interaction Between Ticagrelor and Venlafaxine When Taken Together in Healthy Volunteers

Drug Drug Interaction

United States, Sweden
Rutgers, The State University of New Jersey

Recruiting

Statins for Reduction of Cardiac Toxicity in Patients Receiving HER2 Targeted

Cardiac Toxicity | Early-stage Breast Cancer

United States
Asceneuron S.A.

Recruiting

Drug-Drug Interaction of ASN51 With Fluvoxamine, Itraconazole and Paroxetine in Healthy Subjects

Drug Drug Interaction

Netherlands
Daewoong Pharmaceutical Co. LTD.

Recruiting

Drug-drug Interactions Between DWC202313 and DWC202314 in Healthy Subjects

Drug Drug Interaction

Korea, Republic of
Indiana University
National Institute of General Medical Sciences (NIGMS)

Recruiting

Interaction of CYP2B6 Genotype and Efavirenz With Methadone and Tizanidine PK

Drug-Drug Interaction

United States
VistaGen Therapeutics, Inc.
Parexel

Recruiting

AV-101 Alone and in Combination With Probenecid in Healthy Subjects

Drug Drug Interaction

United States
CMP Development, LLC

Completed

Drug-drug Interaction (DDI) Study of Spironolactone (Perpetrator) and Digoxin (Substrate Drug)

Drug Drug Interaction

India
Pyramid Biosciences

Completed

A Study of PBI-200 With Ritonavir or Cobicistat in Healthy Volunteers

Drug-drug Interaction

United States
Shanghai Pharmaceuticals Holding Co., Ltd

Completed

Drug-drug Interaction Study of SPH3127

Drug Drug Interaction

China
Blade Therapeutics

Completed

Drug-Drug Interaction (DDI) Study in Healthy Volunteers

Drug Drug Interaction

Australia
Antios Therapeutics, Inc

Completed

A Drug-Drug Interaction Study Between ATI-2173 and Midazolam or Clarithromycin in Healthy Subjects

Drug Drug Interaction

Canada
University Hospital, Basel, Switzerland

Completed

Inhibition Metamizole 2020

Drug-drug Interaction

Switzerland
Genfit

Completed

Study to Investigate the Potential Drug-Drug Interaction Between Elafibranor and Indomethacin

Drug-drug Interaction

France
Qure Healthcare, LLC
Aegis Sciences Corporation

Completed

DDI Effectiveness and Clinical Awareness (DECART)

Drug-Drug Interactions

United States
Santhera Pharmaceuticals

Completed

A Study to Assess the Potential for Pre-systemic Inhibition of CYP3A by Idebenone Using Midazolam as a Substrate

Drug-Drug Interaction

France
Indiana University
Indiana Clinical and Translational Sciences Institute

Recruiting

Daily Hand-Held Vibration Therapy

Cancer | Neuropathy | Chemotherapeutic Toxicity | Chemotherapeutic Drug - Induced Nephropathy

United States

Clinical Trials on Drug Toxicity

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Kuwait

Conditions

Rare Diseases

Drug Interventions

Dietary Supplements

Sponsor/Collaborators

Locations