Clinical Trials on Drug Withdrawal

Total 3340 results

Osaka City University

Completed

Prevention of CHOP-induced Chronic Cardiotoxicity

Non-Hodgkin's Lymphoma

Japan
Posit Science Corporation

Completed

Computer-Based Training in Patients With Post-Chemotherapy Cognitive Impairment

Breast Cancer | Memory Disorders | Cognitive Symptoms

United States
Ain Shams University

Recruiting

Evaluation of the Effect of N-acetylcysteine in Preventing Cisplatin-Induced Toxicities in Cancer Patients

Cisplatin Adverse Reaction | Cancer Patients | Cisplatin Ototoxicity | Cisplatin Nephrotoxicity | Cisplatin Induced Peripheral Neuropathy

Egypt
Asociación para Evitar la Ceguera en México

Recruiting

Effect of Intravenous Methylprednisolone and Intravenous Erythropoietin in Toxic Optic Neuropathies: Randomized Clinical Trial.

Methylprednisolone | Treatment | Erythropoietin | Toxic Optic Neuropathy

Mexico
Assistance Publique - Hôpitaux de Paris

Recruiting

Early Detection of Patients at Risk of Developing Anthracycline Cardiotoxicity With TEP/CT -FDG (DETECT)

Lymphoma, Non-Hodgkin | Lymphoma, Hodgkin

France
Barbara Ann Karmanos Cancer Institute
National Cancer Institute (NCI)

Recruiting

AMT-PET in Monitoring Telotristat Etiprate Treatment in Participants With MetastaticNeuroendocrine Neoplasm

Carcinoid Syndrome | Metastatic Nonfunctional Well Differentiated Neuroendocrine Neoplasm

United States
University of Wisconsin, Madison
National Institute on Drug Abuse (NIDA); Tulane University

Completed

Community-Based, Client-Centered Prevention Homes to Address the Rural Opioid Epidemic- Aim 3

Hepatitis C | Harm Reduction | Opioid-use Disorder | Drug Use Disorders

United States
University Health Network, Toronto
Canadian Institutes of Health Research (CIHR); University of Toronto

Active, not recruiting

Evaluation of Myocardial Changes During BReast Adenocarcinoma Therapy to Detect Cardiotoxicity Earlier With MRI (EMBRACE-MRI)

Breast Neoplasms

Canada
Chandrikha Chandrasekhara
TerSera Therapeutics LLC

Withdrawn

Prospective Assessment of Patients With Neuroendocrine Tumors and Current or Prior History of Carcinoid Syndrome or Diarrhea Undergoing Peptide Receptor Radionuclide Therapy With or Without Telotristat Ethyl (NET-PACS)

Diarrhea | Neuroendocrine Tumors | Carcinoid Syndrome

United States
Cliniques universitaires Saint-Luc- Université...

Terminated

Sandostatin (Octreotide LAR) May Lead to Clinical Improvement Through Receptor Occupation Optimisation (SCIROCCO)

Neuroendocrine Tumors | Carcinoid Syndrome
Istanbul Saglik Bilimleri University

Completed

Effectiveness of Mechano-Analgesia and Cold Application on Ecchymosis, Pain and Satisfaction at Subcutaneous Heparin Injection

Injection Site Reaction | Injection Site Bruising
Fudan University

Completed

Comparison Study of Doxorubicin Versus Epirubicin-induced Cardiotoxicity in Patients With DLBCL

Lymphoma

China
Children's Oncology Group
National Cancer Institute (NCI)

Completed

Combination Chemotherapy Plus Dexrazoxane in Treating Patients With Newly Diagnosed Nonmetastatic Osteosarcoma

Sarcoma | Cardiac Toxicity

United States, Canada, Netherlands, Puerto Rico, Switzerland, Australia
National Research Center for Hematology, Russia

Unknown

Russian Clinical Trial of Mesenchymal Cells in Patients With Septic Shock and Severe Neutropenia

Septic Shock | Nonchemotherapy Drug-induced Neutropenia | Neutropenia After Chemotherapy in Oncohematological Patients | Neutropenia in Patients With Aplastic Anemia

Russian Federation
Chinese PLA General Hospital

Unknown

A Chinese Randomized Crossover Study of Erlotinib Versus Docetaxel/Cisplatin in Previously Untreated Stage IIIB/IV Lung Adenocarcinoma With EGFR Mutations

Neoplasms, Lung | Carcinoma, Non-Small Cell Lung | Drug Therapy | Genes, EGFR

China
CytoSorbents, Inc

Recruiting

CytOSorb TreatMent Of Critically Ill PatientS Registry (COSMOS)

Sepsis | Burns | Septic Shock | Trauma | Infectious Disease | Pancreatitis | Acute Respiratory Distress Syndrome | Liver Transplant; Complications | Drug Overdose | Acute Liver Failure | Cardiogenic Shock | Rhabdomyolysis | Acute on Chronic Liver Failure | Hemophagocytic Lymphohistiocytoses | Extracorporeal Life Support and other conditions

Spain, Italy, Germany, Portugal
Guangdong Women and Children Hospital

Unknown

The Treatment of Premature Infants With Brain Injury by Autologous Umbilical Cord Blood Stem Cells

Safety Issues | Effect of Drugs
Centre Hospitalier Universitaire, Amiens
University Hospital, Rouen; University Hospital, Lille

Recruiting

Non-steroidal Anti-inflammatory in Cardiac Surgery (KETOPAIN)

Cardiac Surgery | Acute Postoperative Pain | Pain Intensity | Multimodal Pain Management | Non-steroidal Anti-inflammatory Drugs

France
Marco Antonio Alvarez Gonzalez
Complejo Hospitalario de Navarra; Althaia Xarxa Assistencial Universitària...

Recruiting

Bowel Cleansing With Renal Impairment (BC-RIMP)

Renal Impairment | Adverse Effects of Medical Drugs

Spain
Wills Eye
Optovue

Completed

Peripapillary Blood Flow After Use of Anti-glaucoma Medications: An OCT Angiography Study

Primary Open-angle Glaucoma | Normal Tension Glaucoma | Glaucoma; Drugs

United States
Kaiser Franz Josef Hospital

Withdrawn

The IDEAL-PCI Extended Registry (IDEAL-PCI ext)

Platelet Dysfunction Due to Drugs | Coronary Arterioscleroses

Austria
Zekai Tahir Burak Women's Health Research and Education...
Ankara City Hospital Bilkent

Completed

Zinc Supplementation In Very Low Birth Weight Infants-A Randomised Controlled Trial

Preterm Infant | Effect of Drugs | Zinc Deficiency Disease

Turkey
Erasmus Medical Center

Recruiting

Systemic Treatments for Alopecia Areata Registry (STA2R)

Autoimmune Diseases | Alopecia | Alopecia Areata | Hair Diseases | Alopecia Totalis | Alopecia Universalis | Hair Loss | Alopecia Drugs

Netherlands
Jiangsu HengRui Medicine Co., Ltd.

Suspended

Safety, Tolerability and Pharmacokinetics/Pharmacodynamics (PK/PD) of SHR-1603 in Subjects With Advanced Malignancies

Neoplasms by Histologic Type | Lymphoma | Hematologic Neoplasms | Advanced Cancer | Immunotherapy | Physiological Effects of Drugs

China
Second Affiliated Hospital of Wenzhou Medical University

Unknown

Acceptable Hemodynamic Changes in Dexmedetomidine for Single Intravenous Bolus Injection

Mental Disorders | Pathologic Processes | Postoperative Complications | Delirium | Neurocognitive Disorders | Dexmedetomidine | Molecular Mechanisms of Pharmacological Action | Physiological Effects of Drugs | Analgesics | Hypnotics and Sedatives

China
Azienda Ospedaliera Universitaria Senese

Completed

Antithrombotic Therapy in Patients Undergoing CIED Surgery - HEMATOMA NO MORE Registry

Surgery--Complications | Cardiac Arrhythmia | Hematoma | Device Related Infection | Antithrombotic Drugs

Italy
Al-Azhar University

Active, not recruiting

the Incidence of Necrotizing Enterocolitis in Preterm With Respiratory Distress Syndrome Undergoing Caffeine Therapy

Pharmacological Action of Drug

Egypt
Mayo Clinic
National Cancer Institute (NCI)

Terminated

Perampanel for the Reduction of Seizure Frequency in Patients With High-grade Glioma and Focal Epilepsy

Malignant Glioma | WHO Grade 3 Glioma | Intractable Epilepsy | Seizure Disorder | WHO Grade 2 Glioma

United States
Azienda Ospedaliera Città della Salute e della...

Completed

Subclinical Cardio-toxicities Evaluation With Strain Rate Echocardiography After Chemotherapy and/or Mediastinal Radiotherapy in Patient With Lymphoma (Cardiocare)

Lymphoma, Non-Hodgkin | Hodgkin Lymphoma | Toxicity, Cardiac

Italy
Vanderbilt-Ingram Cancer Center
Entrinsic Bioscience Inc.

Terminated

Enterade in Carcinoid/Non-Carcinoid Syndrome Neuroendocrine Tumor Patients With Quality of Life Limiting Bowel Frequency

Neuroendocrine Tumor | Carcinoid Syndrome

United States
Princess Anna Mazowiecka Hospital, Warsaw, Poland
Medical University of Warsaw

Completed

Monitored vs Standard Supplementation of Vitamin D in Preterm Infants (MOSVID)

Nephrolithiasis | Vitamin D Deficiency | Osteopenia | Drug Overdose

Poland
Oregon Health and Science University

Unknown

Acute Care for Elders (ACE) Program at OHSU Hospital

Delirium | Drug-Related Side Effects and Adverse Reactions | Frail Elderly | Age-Related Cognitive Decline | Hospital Acquired Pressure Ulcer

United States
Boston Medical Center
National Institute on Drug Abuse (NIDA); Emory University; Grady Health System

Completed

Targeting Effective Analgesia in Clinics for HIV - Patient Cohort (TEACH)

HIV Infection | Pain | Drug Dependence

United States
Boston Medical Center
National Institute on Drug Abuse (NIDA); Emory University; Grady Health System

Completed

Targeting Effective Analgesia in Clinics for HIV - Intervention (TEACH)

HIV Infection | Pain | Drug Dependence

United States
University Health Network, Toronto
Canadian Institutes of Health Research (CIHR); MSH-UHN AMO Innovation Fund

Terminated

Efficacy of Cardio-Oncology Rehabilitation Exercise for Women With Breast Cancer and Treatment Related Cardiotoxicity (CORE)

Breast Cancer | Heart Failure, Systolic | Left Ventricular Dysfunction

Canada
University of California, Los Angeles

Completed

UCLA-Amity Parolee Health Promotion Study

Hepatitis B | Hepatitis C | HIV | Drug Addiction

United States
Beijing Neurosurgical Institute

Completed

Application of Platelet Function Test in Prevention of Ischemic Events After Stent Placement in Intracranial Aneurysms (APISIA Trail)

Stents | Unruptured Intracranial Aneurysm | Antiplatelet Drugs

China
University of California, Los Angeles

Completed

Evaluation of Abdominal Wall Block With Liposomal Bupivacaine for Post-Operative Analgesia in Donor Nephrectomy

Pain, Postoperative | Patient Satisfaction | Physiological Effects of Drugs | Analgesics, Opioid | Analgesics, Non-Narcotic | Peripheral Nervous System Agents | Return to Work | Activity, Sexual

United States
Washington University School of Medicine
American Academy of Otolaryngology-Head and Neck Surgery Foundation

Recruiting

Head and Neck Cancer Survivorship Ototoxicity Screening (SOS)

Head and Neck Cancer Survivors | Cancer of the Head and Neck Surviors

United States
Academisch Medisch Centrum - Universiteit van Amsterdam...

Recruiting

Changes in Circadian Rhythm After Anaesthesia in Children (CLOCKSkids)

Sleep | Sleep Disturbance | Anesthesia | Sleep Disorders, Circadian Rhythm | Circadian Rhythm Sleep Disorder | Circadian Rhythm Disorder Caused by Drug | Circadian Rhythm Sleep Disorder, Jet Lag Type | Jet Lag

Netherlands
The Cleveland Clinic

Recruiting

Global Cardio Oncology Registry (G-COR)

Cardiovascular Diseases | Breast Cancer | Cardiotoxicity | Hematologic Malignancy | Immune Checkpoint Inhibitor-Related Myocarditis

United States
University Medical Center Groningen
Radboud University Medical Center; Maastricht University Medical Center; Erasmus... and other collaborators

Recruiting

Comparison of Standard Dose Alectinib to Alectinib in Adjusted Dose Based on Alectinib Bloodlevels (ADAPT ALEC)

Carcinoma, Non-Small-Cell Lung | Lung Cancer | Drug Monitoring | Anaplastic Lymphoma Kinase Gene Mutation | Anaplastic Lymphoma Kinase Gene Translocation

Netherlands, France
Abramson Cancer Center at Penn Medicine
American Heart Association

Recruiting

Mechanisms, Predictors, and Social Determinants of Cardiotoxicity in Prostate Cancer (PCT)

Cardiovascular Diseases | Prostate Cancer | Drug-Related Side Effects and Adverse Reactions | Cardiotoxicity

United States
M.D. Anderson Cancer Center

Recruiting

An Investigational Scan (Dual Energy CT) in Detecting Gastrointestinal Carcinoid Tumors

Carcinoid Tumor | Carcinoid Syndrome | Metastatic Carcinoid Tumor | Digestive System Neuroendocrine Tumor G1

United States
ANRS, Emerging Infectious Diseases
Institut National de la Santé Et de la Recherche Médicale, France; University... and other collaborators

Recruiting

Early Treatment of Vulnerable Individuals With Non-Severe SARS-CoV-2 Infection (COVERAGE-A)

Covid19 | SARS-CoV2 Infection | Severe Acute Respiratory Syndrome Coronavirus 2 | Covid19 Drug Treatment

Burkina Faso, Guinea
Groupe Hospitalier Pitie-Salpetriere

Recruiting

Reporting, Evaluating, Preventing and Treating the Cardiotoxicity Induced by Anticancer Drugs During a Specific Cardio-oncology Consult and Follow up in Routine Care (NEOCARDIO)

Metabolic Disorder | Cardiac Insufficiency | Oncologic Complications | Cardiac Complication | Cardiovascular Complication | Cardiovascular Insufficiency | Cardiac Disorder | Vascular Disorder

France
Sidney Kimmel Comprehensive Cancer Center at Johns...
Avon Foundation

Terminated

Detection and Prevention of Anthracycline-Related Cardiac Toxicity With Concurrent Simvastatin

Breast Cancer | Stage I Breast Cancer | Stage II Breast Cancer | Stage III Breast Cancer

United States
The Hospital of Vestfold
Oslo University Hospital; University of Southern Denmark; University of New Mexico and other collaborators

Active, not recruiting

Factors Predicting Outcome in Group Treatment of Alcohol Use Disorders (AUDs)

Personality Disorders | Cognitive Impairment | Substance Use Disorders | Cognitive Deficit | Psychiatric Disorder | Drug Abuse | Alcohol Abuse | Alcohol Use Disorder (AUD)

Norway
Cliniques universitaires Saint-Luc- Université...

Terminated

Predictive Value of ProCalcitonin for the Detection of Bacteraemia in Patients Presenting to the Emergency Department for Low Risk Chemo-induced Febrile Neutropenia (CALIF)

Febrile Neutropenia, Drug-Induced

Belgium
Wake Forest University Health Sciences
National Cancer Institute (NCI)

Completed

MRI in Detecting Heart Damage in Patients With Cancer Receiving Chemotherapy With Exercise Capacity Addendum

Breast Cancer | Malignant Neoplasm | Cardiac Toxicity

United States

Clinical Trials on Drug Withdrawal

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Uzbekistan

Conditions

Rare Diseases

Drug Interventions

Dietary Supplements

Sponsor/Collaborators

Locations