Clinical Trials on Drug-drug Interaction Study in Italy

Total 83 results

Fondazione IRCCS Ca' Granda, Ospedale Maggiore...

Not yet recruiting

A Big Data Approach to Predict NEOnatal Acute Kidney Injury in Newborns expoSed to nephroTOxic Drugs (NeoAKI STOP) (NeoAKISTOP)

Premature Birth | Acute Kidney Injury | Drug Use | Machine Learning | Newborn Morbidity | Drug Interaction | Drug Toxicity | Drug-Induced Nephropathy

Italy
Mario Luca Morieri

Recruiting

Genetic-Dependent Cardiovascular Response to PPAR-Alpha Agonist Fenofibrate (MAGNETIC)

Cardiovascular Diseases | Type 2 Diabetes | Pharmacogenomic Drug Interaction

Italy
J.J.Swen
Karolinska Institutet; Medical University of Vienna; Uppsala University; St. Antonius... and other collaborators

Completed

PREemptive Pharmacogenomic Testing for Preventing Adverse Drug REactions (PREPARE)

Adverse Drug Reaction

Austria, Netherlands, Italy, Greece, Slovenia, Spain, United Kingdom
University of Milan
Federico II University; University of Milano Bicocca

Unknown

Educational and Informative Interventions to Tackle Inappropriate Use of Drugs in Italy (EDUREDRUG)

Inappropriate Drug Prescription and Use

Italy
Mario Negri Institute for Pharmacological Research

Completed

E-learning to Improve Oral Anticoagulant Use in Hospitalized Older People With AF (SIM-AF)

Atrial Fibrillation | Elderly | Geriatrics | Simulation Training | Anticoagulant Drugs | Internal Medicine | Drug Prescriptions

Italy
Catholic University of the Sacred Heart

Recruiting

Medication Related Osteonecrosis of the Jaws (MRONJ) in a Cohort of Patients Treated by Antiresorptive Drugs

Osteonecrosis of the Jaw | Bisphosphonate-Associated Osteonecrosis | Bisphosphonate-Associated Osteonecrosis of the Jaw | Osteonecrosis Due to Drugs, Jaw | Osteonecrosis Due to Drug

Italy
Fondazione Poliambulanza Istituto Ospedaliero

Unknown

Reducing Errors In The Neonatal Intensive Care Unit (SAPHET-i)

Medication Errors and Other Product Use Errors and Issues | Adverse Drug Event

Italy
Fondazione Policlinico Universitario Agostino Gemelli...

Completed

Maternal Lateral Tilt and Cardiac Output in Caesarean Section

Hypotension Drug-Induced

Italy
Ospedale San Donato

Unknown

Comparison of Sirolimus vs Paclitaxel Drug Eluting Balloon for Below-the-knee Angioplasty in Critical Limb Ischemia (DebateBTKDuell)

Drug Effect | Critical Limb Ischemia

Italy
European Institute of Oncology

Recruiting

Myocardial Fibrosis Identification in Patients With Anthracycline-induced Cardiotoxicity

Cardiomyopathy Due to Drug

Italy
Air Liquide Santé International
Orion Corporation, Orion Pharma

Completed

Xenon Compared to Sevoflurane and Total Intravenous Anaesthesia for Coronary Artery Bypass Graft Surgery

Coronary Artery Disease | Coronary Artery Bypass Graft Surgery | General Anesthetic Drug Allergy

France, Italy, Germany, Netherlands
Neuromed IRCCS

Recruiting

Functional Study of Inhibitory Neurotransmission in the Human Epileptic Brain.

Drug Resistant Epilepsy

Italy
Oncologia Medica dell'Ospedale Fatebenefratelli
Mario Negri Institute for Pharmacological Research

Completed

PAINTER: Polymorphism And INcidence of Toxicity in ERibulin Treatment

Metastatic Breast Cancer | Toxicity | Neurotoxicity | Adverse Drug Event | Drug Toxicity

Italy
University of Pavia
University of Bologna; University of Catanzaro

Completed

Outcome Study in Refractory Epilepsy (SOPHIE) (SOPHIE)

Epilepsy

Italy
Thermo Fisher Scientific Oy
ICON plc

Completed

Stability of Tacrolimus, Cyclosporine A, Everolimus and Sirolimus in Whole Blood Patient Samples

Transplantation Drugs Stability

Italy
IRCCS Burlo Garofolo

Recruiting

Active Pharmacovigilance of Anti-cancer Medicines

Oncology | Drugs | Pharmacovigilance

Italy
Azienda Usl di Bologna

Recruiting

Tele-epic (Telemedicine for Epilepsy Care) (Tele-epic)

Epilepsy | Refractory Epilepsy | Epileptic Encephalopathy

Italy
Advancell - Advanced In Vitro Cell Technologies...
Cromsource

Completed

Safety and Efficacy Placebo Controlled Study of ATH008 Cream in PPES Patients Secondary to Capecitabine

Palmar-Plantar Erythrodysesthesia Syndrome

Spain, Belgium, Germany, Italy
IRCCS Eugenio Medea

Recruiting

Contribution of Genetics, Non-invasive Methods and Neuropsychology in Focal Cryptogenic Epilepsies

Epilepsies, Partial | Epilepsy Intractable

Italy
Marco J. Bruno
Boston Scientific Corporation

Recruiting

Prevalence of Multidrug Resistant Micro-organism Carriage in Patients Undergoing an ERCP in Four Different Countries (PREVENT)

Cholangiopancreatography, Endoscopic Retrograde | Drug Resistance, Multiple, Bacterial

United States, India, Netherlands, Italy
Università degli Studi dell'Insubria

Not yet recruiting

Combined Lactobacilli (Reuteri LMG P-27481 and GG ATCC 53103) to Prevent Antibiotic Associated Symptoms in Children

Abdominal Pain | Diarrhea Caused by Drug

Italy
IRCCS Sacro Cuore Don Calabria di Negrar

Recruiting

Molecular Diagnostics of Bacterial Infections and Antibiotic Resistance in Blood Samples and Rectal Swabs Using Real Time PCR-ARES PCR Methods

Drug Resistant Bacterial Infection

Italy
Istituto Scientifico Romagnolo per lo Studio e...

Recruiting

Clinical Study Comparing Different Strategies to Increase Adherence to Oral Therapies in Oncohematology

Cancer | Solid Tumor | Hematologic Malignancy | Oral Drug Administration

Italy
Protherics Medicines Development Limited
Resonance Health

Recruiting

Retrospective Registry Study of Patients With Cancer Treated With High-dose Methotrexate

Acute Kidney Injury | Drug Toxicity

Spain, France, Italy
UCB Biopharma SRL

Terminated

A Study to Test the Efficacy and Safety of Padsevonil as Treatment of Focal-onset Seizures in Adult Subjects With Drug-resistant Epilepsy (DUET)

Drug-Resistant Epilepsy | Focal-Onset Seizures

United States, Australia, Belgium, Bosnia and Herzegovina, Bulgaria, Croatia, Czechia, Denmark, Estonia, Finland, France, Germany, Greece, Hungary, Ireland, Italy, Japan, Norway, Poland, Portugal, Romania, Serbia, Slovakia, Spain, Sweden, Switzerlan... and more
UCB Biopharma SRL

Terminated

Study to Test the Safety and Efficacy of Padsevonil as Adjunctive Treatment of Focal-onset Seizures in Adult Subjects With Drug-resistant Epilepsy

Drug-Resistant Epilepsy | Focal-Onset Seizures

United States, Australia, Belgium, Bosnia and Herzegovina, Bulgaria, Canada, Croatia, Czechia, Denmark, Estonia, Finland, France, Germany, Greece, Hungary, Ireland, Italy, Japan, Lithuania, Mexico, Poland, Romania, Serbia, Slovakia, Spain, Turk... and more
UCB Biopharma S.P.R.L.

Completed

Study to Test the Efficacy and Safety of Padsevonil as Adjunctive Treatment of Focal-onset Seizures in Adults With Drug-resistant Epilepsy (ARISE)

Focal-Onset Seizures | Drug-resistant Epilepsy

United States, Australia, Belgium, Bulgaria, Canada, Czechia, France, Germany, Hungary, Italy, Japan, Lithuania, Mexico, Poland, Portugal, Slovakia, Spain, Turkey, United Kingdom
Ospedale San Raffaele

Completed

Pharmacogenetics of Torasemide and Spironolactone in Hypertension Treatment (ALTUM)

Hypertension | Drug Effect | Genetic Predisposition

Italy
European Organisation for Research and Treatment...

Terminated

Chemotherapy Plus Radiation Therapy With or Without Amifostine in Treating Patients With Locally Advanced Cancer of the Nasopharynx

Head and Neck Cancer | Radiation Toxicity | Oral Complications | Drug/Agent Toxicity by Tissue/Organ

Spain, France, Belgium, Italy, United Kingdom, Turkey
Istituto Scientifico Romagnolo per lo Studio e...
Kessler Foundation

Unknown

Participatory Research for Fine-tuning of a 2.0 System to Optimise Home Management of Oral Cancer Therapies.

Cancer | Oral Drug Administration

Italy
Zogenix, Inc.
Zogenix International Limited, Inc., a subsidiary of Zogenix, Inc.

Terminated

European Non-interventional Study on Refractory Epilepsy With Developmental Delay

Refractory Epilepsy | Development Delay

Germany, Spain, France, Italy
IRCCS Policlinico S. Donato

Completed

PLATelet Function Operating Room Monitoring (PLATFORM)

Bleeding | Platelet Dysfunction Due to Drugs

Italy
University of Pavia
IRCCS ISTITUTO NEUROLOGICO CASIMIRO MONDINO

Recruiting

Ketonemia Through Menstrual Cycle (KETOMENS)

Epilepsy | Drug Resistant Epilepsy | Ketogenic Dieting | GLUT1DS1 | Menstrual Epilepsy

Italy
H. Lundbeck A/S

Recruiting

A Study of Eptinezumab in Participants With Migraine and Medication Overuse Headache

Migraine | Medication Overuse Headache

Spain, Italy, Denmark, France, Netherlands, Australia, Georgia, Germany, Norway, Sweden, United States
Cyberonics, Inc.

Completed

PuLsE 2-Observational Long-Term Effectiveness Follow-Up Study of PuLsE 1 (PuLsE 2)

Epilepsy

France, Belgium, Italy, United Kingdom, Germany, Canada, Netherlands
MedtronicNeuro

Completed

Product Surveillance Registry- Deep Brain Stimulation for Epilepsy (MORE)

Refractory Epilepsy

Belgium, Sweden, Austria, United Kingdom, Poland, Germany, Portugal, Canada, Finland, Hungary, Italy, Netherlands, Russian Federation
Azienda Ospedaliera, Universitaria Policlinico...
Marinella Astuto

Recruiting

Spinal Anesthesia in Caesarean Section

Bradycardia | Cesarean Section Complications | Hypotension Drug-Induced | Spinal Anesthetics Causing Adverse Effects in Therapeutic Use

Italy
European Institute of Oncology

Active, not recruiting

Prevention of Anthracycline-induced Cardiotoxicity (ICOS-ONE)

Cancer

Italy
Istituto Scientifico Romagnolo per lo Studio e...

Terminated

Complementary Vaccination With Dendritic Cells Pulsed With Autologous Tumor Lysate in Resected Stage III and IV Melanoma Patients. (ACDC)

Malignant Melanoma | Adjuvant Drug Therapy | Vaccin Therapy

Italy
IRCCS Azienda Ospedaliero-Universitaria di Bologna

Unknown

Adequacy of Pain Treatment in Radiotherapy

Cancer Pain | Analgesic Drugs

Italy
European Institute of Oncology

Completed

Prevention of Chemotherapy-induced Cardiotoxicity in High-risk Patients

Cardiotoxicity | Chemotherapeutic Toxicity

Italy
Amgen

Completed

A Study to Evaluate the Efficacy and Safety of Erenumab in Adults With Medication Overuse Headache

Migraine Headache

United States, Austria, Australia, Czechia, Finland, France, Hungary, Italy, Poland, Portugal, Spain, United Kingdom
Azienda Sanitaria-Universitaria Integrata di Udine

Recruiting

Optimized Antibiotic Therapy in Patients With Subarachnoid Haemorrhage (ES) and Cerebral Haemorrhage (EC) (TANDEM)

Subarachnoid Hemorrhage | Therapeutic Drug Monitoring | Intracerebral Hemorrhage

Italy
University Hospital of Ferrara

Completed

Opicapone as Adjunctive Therapy to Levodopa-Carbidopa Intestinal Gel in Parkinson's Disease (OPAILEC)

Parkinson Disease | Effect of Drug

Italy
Fondazione ANT Italia ONLUS

Completed

Study on Quality of Life in Advanced Cancer Patients With Opioid-induced Constipation Treated With Naloxegol

Cancer | Opioid Use | Constipation Drug Induced

Italy
Sándor Beniczky
Hospital del Mar; Centro Hospitalar e Universitário de Coimbra, E.P.E.; Motol... and other collaborators

Active, not recruiting

Clinical Utility of Automated Electric Source Imaging in Presurgical Evaluation (PROMAESIS)

Surgery | Refractory Epilepsy | Electroencephalography | Brain Imaging

Spain, Portugal, Austria, Czechia, Denmark, Germany, Italy, Romania
Novartis Pharmaceuticals

Completed

Safety and Efficacy of AQW051 in L-dopa Induced Dyskinesias in Patients With Parkinson's Disease

Dyskinesias | Drug-induced

United States, France, Germany, Italy
ITAB - Institute for Advanced Biomedical Technologies

Unknown

Transcranial Magnetic Stimulation for Cocaine Addiction (BRAINSWITCH)

Substance Use Disorders | Cocaine-Related Disorders | Cocaine Dependence | Mental Disorder | Drug Dependence | Chemical Addiction

Italy
IRCCS Eugenio Medea

Recruiting

Structural-functional Connectome in Drug-resistant Epilepsies and Neurodevelopmental Syndromes With Epilepsy

Epilepsy | Angelman Syndrome | Dup15q Syndrome

Italy
Azienda Ospedaliera Universitaria Integrata Verona
Societa Italiana dell'Ipertensione Arteriosa

Not yet recruiting

Study of Adherence to Antihypertensive Drugs and Statins by Hair Analysis (INNOVA)

Dyslipidemias | Treatment Adherence | Arterial Hypertension | Antihypertensive Drugs | Statins

Italy

Clinical Trials on Drug-drug Interaction Study in Italy

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