Clinical Trials on EGFR and/or ROS Mutant NSCLC in United Kingdom
Total 112 results
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Massachusetts General HospitalNot yet recruitingGlioblastoma Recurrent, EGFR vIII Mutant | Newly Diagnosed Glioblastoma, EGFRvIII Mutant | Recurrent Glioblastoma, EGFR vIII NegativeUnited States
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AstraZenecaNo longer available
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AstraZenecaCompletedCaucasian Patients With EGFR Mutation Positive Advanced NSCLCBulgaria, Italy, Poland, Spain, Turkey, United Kingdom, Romania, Norway, Hungary, Portugal, Greece, Switzerland, France
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Memorial Sloan Kettering Cancer CenterAstellas Pharma US, Inc.CompletedEGFR-Mutant Lung CancerUnited States
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AstraZenecaCompletedEGFR Mutation Status in aNSCLC Patients (Locally Advanced and/or Metastatic Disease) With Adenocarcinoma and Non-adenocarcinoma Histologies.Italy, Spain, United Kingdom, Sweden, Japan, Netherlands, Germany, France
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Memorial Sloan Kettering Cancer CenterAstraZeneca; Genentech, Inc.CompletedNon-small Cell Lung Cancer | EGFR-mutant Lung CancersUnited States
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Molecular Partners AGTerminatedEGFR-mutated NSCLC (Disorder)United States
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Rain Oncology IncTerminatedNSCLC Stage IIIB | NSCLC, Recurrent | NRG1 Fusion | EGFR Exon 20 Insertion Mutation | NSCLC, Stage IIIC | NSCLC, Stage IV | HER2-activating Mutation | ERBB FusionUnited States, Canada, Hong Kong
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Sierra Oncology, Inc.TerminatedEGFR Mutated EGFR TKI Naive Metastatic NSCLCUnited States
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MapKure, LLCRecruitingColorectal Cancer | Pancreatic Ductal Cancer | Advanced or Metastatic RAS Mutant Colorectal and Pancreatic Ductal CancersAustralia, United States
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University of VirginiaActive, not recruitingReal-Time Monitoring of Symptoms in Lung Cancer Patients Receiving Oral Targeted Therapies (Lung001)Lung Cancer | ALK Gene Mutation | MET Gene Mutation | KRAS Mutation-Related Tumors | RET Gene Mutation | EGFR Gene Mutation | EGFR | ROS1 Gene Mutation | BRAFUnited States
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Nested Therapeutics, IncRecruitingGlioma | Melanoma | NSCLC | Oncology | Solid Tumor, Adult | MEK Mutation | RAF Gene Mutation | Ras (KRAS or NRAS) Gene Mutation | MAPK Pathway Gene MutationUnited States, Australia
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Bridge Biotherapeutics, Inc.RecruitingEGFR Mutant Advanced Non-Small Cell Lung CancerKorea, Republic of, United States
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J Ints BioRecruitingEGFR Mutant Advanced Non-small Cell Lung CancerKorea, Republic of, United States, Thailand
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Blueprint Medicines CorporationActive, not recruitingNeoplasms | Neoplasms by Histologic Type | Lung Diseases | Neoplasms by Site | Adenocarcinoma | Carcinoma | Carcinoma, Non-Small-Cell Lung | Respiratory Tract Neoplasms | Carcinoma, Bronchogenic | Bronchial Neoplasms | Metastatic Lung Cancer | Antineoplastic Agents | Brain Metastases | Lung Neoplasm Malignant | EGFR... and other conditionsUnited States, Canada, Korea, Republic of, Japan, Taiwan
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Taiho Oncology, Inc.RecruitingAdvanced or Metastatic NSCLC Harboring Epidermal Growth Factor Receptor (EGFR) Exon 20 Insertion (ex20ins) MutationsUnited States, Japan, Spain, France, Australia, Italy, Korea, Republic of, United Kingdom, Canada, Germany, Turkey, Hong Kong
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Puma Biotechnology, Inc.TerminatedSolid Tumors Harboring Somatic HER2 or EGFR Exon 18 MutationsFrance, United States, Spain, Belgium, United Kingdom, Serbia, Australia, Israel, Canada, Denmark, Ireland, Italy, Korea, Republic of
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Novartis PharmaceuticalsActive, not recruitingAdvanced EGFRmutant NonSmallSellLungCancer (NSCLC),KRAS G12-mutant NSCLC,Esophageal SquamousCellCancer (SCC),Head/Neck SCC,MelanomaTaiwan, United States, Netherlands, Spain, Korea, Republic of, Italy, Japan, Canada, Singapore
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ArriVent BioPharma, Inc.RecruitingAdvanced Non-Small Cell Lung Cancer | Metastatic Non-Small Cell Lung Cancer | Non-Small Cell Lung Cancer (NSCLC) | HER2 Exon 20 Mutations | EGFR Exon 20 Mutations | EGFR Uncommon Mutations, Including G719X and S768IUnited States, Australia, Spain, United Kingdom, France, Italy, China, Korea, Republic of, Canada, Japan, Netherlands
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Pixium Vision SACompletedRetinitis Pigmentosa | Choroideremia | Cone Rod DystrophyAustria, Spain, United Kingdom, France, Germany
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Scorpion Therapeutics, Inc.RecruitingNon-Small Cell Lung Cancer | NSCLC | EGFR/HER2 Exon 20 Insertion MutationUnited States, Taiwan
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PfizerCompletedBRAF or NRAS Mutant Metastatic MelanomaUnited States, Netherlands, Italy, Germany, Switzerland
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Memorial Sloan Kettering Cancer CenterActive, not recruitingNSCLC | Non Small Cell Lung Cancer | Triple Negative Breast Cancer | Non Small Cell Lung Cancer Metastatic | NSCLC Stage IV | TNBC - Triple-Negative Breast Cancer | NSCLC Stage IV Without EGFR/ALK MutationUnited States, Canada
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PfizerCompletedLocally Advanced or Metastatic NRAS Mutant MelanomaUnited States, Australia, Germany, Italy, Netherlands
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Astellas Pharma Global Development, Inc.TerminatedNon-small Cell Lung Cancer (NSCLC) | Epidermal Growth Factor Receptor (EGFR) MutationsUnited States
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National Eye Institute (NEI)RecruitingCone-Rod Degeneration | Rod-Cone DegenerationUnited States, Australia
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Palobiofarma SLOhio State UniversityActive, not recruiting
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PfizerCompletedALK-positive Non Small Cell Lung Cancer (NSCLC) and ROS1-positive NSCLCUnited States, Canada, Australia, Taiwan, Singapore, Japan, Korea, Republic of, Spain, Belgium, Switzerland, France, Germany, Hong Kong, Italy
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Massachusetts General HospitalNational Cancer Institute (NCI)CompletedNon-small Cell Lung Cancer Metastatic | Targetable Oncogenes (EGFR, ALK, ROS1)United States
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Ascidian Therapeutics, IncRecruitingStargardt Disease | Stargardt Disease 1 | Juvenile Macular Degeneration | Cone Rod DystrophyUnited States
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Erasca, Inc.RecruitingAdvanced or Metastatic NRAS-mutant MelanomaUnited States
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AstraZenecaCompletedLocally Advanced or Metastatic NSCL Cancer Stage IIIB IVUnited Kingdom
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SparingVisionRecruiting
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Cancer Research UKHummingbird BioscienceRecruitingMelanoma | Cervical Cancer | Gastric Cancer | Pancreatic Cancer | Ovarian Cancer | Hepatocellular Carcinoma (HCC) | Bladder Cancer | Triple Negative Breast Cancer | Endometrial Cancer | Castration-resistant Prostate Cancer | Non-small Cell Lung Cancer (NSCLC) | Oesophageal Cancer | RAS Wild Type Colorectal Cancer | Squamous Cell Cancer of the Head and NeckUnited Kingdom
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AO Innovation Translation CenterTerminatedDeformity of Bone | Limb Deformities Congenital | Limb Deformities Nos (Acquired)United States, Switzerland
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UCB Biopharma S.P.R.L.Pharm Research Associates (UK) Ltd.CompletedEpilepsy With POS With or Without Secondary GeneralizationDenmark, Germany, Hungary, Ireland, Italy, Netherlands, Norway, Spain, United Kingdom
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University of Colorado, DenverRecruitingNon-Small Cell Lung Cancer | ALK Gene Mutation | EGFR Gene Mutation | BRAF V600E | Non-Small Cell Carcinoma of Lung, TNM Stage 4 | ROSE Cluster 1United States
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Novartis PharmaceuticalsTerminatedCeritinib (LDK378) for Patients Whose Tumors Have Aberrations in ALK or ROS1 (SIGNATURE) (SIGNATURE)Tumors With Aberrations in ALK or ROS1United States
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Pasithea Therapeutics Corp.RecruitingAdvanced Solid Tumors | RAS Mutation | NF1 Mutation | RAF MutationUnited States
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PYC TherapeuticsRecruitingRetinitis Pigmentosa | Eye Diseases, Hereditary | Retinal Dystrophies | Retinal Dystrophy Rod | Retinal Dystrophy Rod ProgressiveUnited States, Australia
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Genzyme, a Sanofi CompanyCompletedAlport Syndrome Patients With eGFR Between 45-90 ml/Min/1.73 m2France, Germany, Australia, United States, United Kingdom, Canada
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Monte Rosa Therapeutics, IncRecruitingNSCLC | Prostate Cancer | SCLC | DLBCL | High Grade Neuroendocrine Cancer | L-MYC and N-MYC Amplified Solid Tumors | NSCLC With High or Low L-MYC or N-MYC Expression | HR-positive, HER2-negative Breast CancerUnited States, Canada
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Advocate Health CareActive, not recruiting
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Novartis PharmaceuticalsActive, not recruitingLocally Advanced or Metastatic KRAS G12C-mutated NSCLC With a PD-L1 Expression <1% or a PD-L1 Expression ≥ 1% and an STK11 Co-mutationSpain, Italy, Austria, Netherlands, United Kingdom, Thailand, France, Belgium, China, Germany, Greece, Argentina, Turkey, Malaysia, Portugal, Brazil, United States, Hungary, India
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St. Jude Children's Research HospitalNovartis PharmaceuticalsCompletedGlioma | Neoplasms | Glioblastoma | Neoplasms, Neuroepithelial | Central Nervous System Neoplasms | Brain Cancer | Brain Tumor | Ependymoma | Medulloblastoma | Anaplastic Astrocytoma | Anaplastic Ganglioglioma | Anaplastic Ependymoma | Anaplastic Oligodendroglioma | Pineoblastoma | Recurrent Medulloblastoma | CNS Tumor | Pediatric... and other conditionsUnited States
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ShireCompletedRetinopathy of Prematurity (ROP)United States, Italy, Netherlands, Poland, Sweden, United Kingdom
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Black Diamond Therapeutics, Inc.RecruitingNon-Small Cell Lung Cancer | NSCLC | Metastatic Lung Cancer | Metastatic Lung Non-Small Cell Carcinoma | EGF-R Positive Non-Small Cell Lung Cancer | Advanced Lung Carcinoma | EGFR-TKI Resistant Mutation | Advanced Non-Small Cell Squamous Lung Cancer | Epidermal Growth Factor Receptor C797S | Epidermal...United States
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National Eye Institute (NEI)TerminatedInherited Retinal Degeneration | Inherited Ophthalmic DiseasesUnited States
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Food and Drug Administration (FDA)National Eye Institute (NEI)RecruitingAge-Related Macular Degeneration | Retinal Degeneration | Retinitis Pigmentosa | Usher Syndromes | Cone Dystrophy | Rod Dystrophy | Cone Rod Dystrophy | Hydroxychloroquine Retinopathy | Late-Onset Retinal Degeneration | Rod Cone DystrophyUnited States
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National Human Genome Research Institute (NHGRI)CompletedGenetics | Growth Disorder | PIK3CA-Related Overgrowth Spectrum (PROS)United States