Clinical Trials on Early Alzheimer´s Disease

Total 3916 results

Boston Children's Hospital
CureAP4 Foundation

Recruiting

Registry and Natural History Study for Early Onset Hereditary Spastic Paraplegia (HSP)

Hereditary Spastic Paraplegia | SPG50 | SPG47 | SPG51 | SPG52 | AP4-related Hereditary Spastic Paraplegia | Early Onset Hereditary Spastic Paraplegia | SPG4 | SPG3A | SPG15 | SPG11

United States
Jonsson Comprehensive Cancer Center
National Cancer Institute (NCI); National Institutes of Health (NIH)

Active, not recruiting

Mindfulness Meditation or Survivorship Education in Improving Behavioral Symptoms in Younger Stage 0-III Breast Cancer Survivors (Pathways to Wellness) (PTW)

Stage 0 Breast Cancer | Cancer Survivor | Stage IIIA Breast Cancer | Stage IIIB Breast Cancer | Early-Stage Breast Carcinoma | Stage IA Breast Cancer | Stage IB Breast Cancer | Stage IIA Breast Cancer | Stage IIB Breast Cancer | Stage IIIC Breast Cancer

United States
Skane University Hospital
Lund University

Recruiting

The Swedish BioFINDER 2 Study (BioFINDER2)

Parkinson Disease | Dementia | Alzheimer Disease | Frontotemporal Degeneration | Mild Cognitive Impairment | Lewy Body Disease | Multiple System Atrophy | Corticobasal Degeneration | Progressive Supranuclear Palsy | Semantic Dementia | Parkinson-Dementia Syndrome | Progressive Nonfluent Aphasia

Sweden
Biogen

Completed

Cognitive, Behavioral, and Functional Change in Behavioral Variant Frontotemporal Dementia (bvFTD) (FORWARD)

Frontotemporal Dementia | Behavioral Variant Frontotemporal Dementia

United States
AstraZeneca

Completed

Nexium Capsules Helicobacter Pylori Specific Clinical Experience Investigation

Early Gastric Cancer | Gastric Ulcer | Duodenal Ulcer | Gastric Mucosa-associated Lymphoid Tissue (MALT) | Lymphoma Idiopathic Thrombocytopenic Purpura

Japan
I.R.C.C.S. Fondazione Santa Lucia
Alzheimer's Drug Discovery Foundation

Active, not recruiting

Dopaminergic Therapy for Frontotemporal Dementia Patients

Mental Disorders | Brain Diseases | Central Nervous System Diseases | Nervous System Diseases | Neurologic Manifestations | Neurobehavioral Manifestations | Neurocognitive Disorders | Neurodegenerative Diseases | TDP-43 Proteinopathies | Proteostasis Deficiencies | Dementia | Language Disorders | Communication... and other conditions

Italy
Russian Federation of Anesthesiologists and Reanimatologists
Kuban State Medical University

Recruiting

The Role of Concomitant Diseases in Postoperative Complications Risk Stratification. (STOPRISK)

Stroke | Epilepsy | Diabetes | Chronic Kidney Diseases | Chronic Obstructive Pulmonary Disease | Neuromuscular Diseases | Parkinson's Disease | Anemia | Coronary Heart Disease | Chronic Heart Failure | Alzheimer's Disease | Bronchial Asthma | Heart Rhythm Disorders

Russian Federation
Indian Council of Medical Research
King George's Medical University; Lady Hardinge Medical College; King Edward... and other collaborators

Not yet recruiting

Selective Antibiotics When Symptoms Develop Versus Universal Antibiotics for Preterm Neonates (SAUNA)

Sepsis | Preterm Birth | Preterm Premature Rupture of Membrane | PROM, Preterm (Pregnancy) | Early-Onset Neonatal Sepsis

India
Mayo Clinic
Patient-Centered Outcomes Research Institute

Completed

Behavioral Interventions to Prevent or Delay Dementia

Mild Cognitive Impairment | Memory Disorders | Memory Impairment | Impaired Cognition | Mild Dementia | Mild Cognitive Disorder | Amnestic Disorder | Dementia and Amnestic Conditions | Poor Short-term Memory

United States
AviadoBio Ltd

Recruiting

A Study to Evaluate the Safety and Effect of AVB-101, a Gene Therapy Product, in Subjects With a Genetic Sub-type of Frontotemporal Dementia (FTD-GRN) (ASPIRE-FTD)

Frontotemporal Dementia | FTD | FTD-GRN | Dementia, Frontotemporal

Netherlands, Spain, Poland, United States
Passage Bio, Inc.

Recruiting

A Study of PBFT02 in Patients With Frontotemporal Dementia and Progranulin Mutations (FTD-GRN) (upliFT-D)

Frontotemporal Dementia | FTD | Dementia Frontotemporal | FTD-GRN

United States, Brazil, Italy, Portugal, Canada
Genmab
AbbVie

Terminated

A Study on the Safety of GEN1044 (DuoBody®-CD3x5T4) in Patients With Malignant Solid Tumors

Esophageal Cancer | Prostate Cancer | Bladder Cancer | Non-small Cell Lung Cancer (NSCLC) | Uterine Cancer | Triple Negative Breast Cancer (TNBC) | Squamous Cell Carcinoma of Head and Neck (SCCHN) | Locally Advanced or Metastatic Solid Tumor(s)

Spain, Israel, United States, Denmark
Axovant Sciences Ltd.

Completed

Study Evaluating Nelotanserin for Treatment of REM Sleep Behavior Disorder in Subjects With Dementia (DLB or PDD)

REM Sleep Behavior Disorder | Dementia With Lewy Bodies | Parkinson's Disease Dementia

United States
University of California, San Francisco
Forest Laboratories

Completed

Memantine (10mg BID) for the Frontal and Temporal Subtypes of Frontotemporal Dementia

Semantic Dementia | Frontal Lobe Dementia | Frontotemporal Lobe Dementia

United States
University of Aarhus

Completed

Three Birds With One Stone

Colorectal Neoplasms | Colorectal Cancer | Colorectal Carcinoma | Uterine Cervical Cancer | Uterine Cervical Neoplasm | Mass Screening | Early Detection of Cancer | Uterine Cervix Cancer

Denmark
Advocate Health Care

Completed

Psychometric Properties of the SMART Feeding Tool

Trauma and Stressor Related Disorders | Nurse's Role | Premature Infant Disease | Feeding; Difficult, Newborn | Malnutrition, Infant | Dysphagia of Newborn | Feeding Disorder of Infancy or Early Childhood | Deglutition Disorders in Infants

United States
Kuopio University Hospital

Active, not recruiting

Sociodemographic Factors and Criminal Behaviour Preceding Neurodegenerative Disease - Retrospective Register Study (DEGERWD)

Parkinson Disease | Neurodegenerative Diseases | Amyotrophic Lateral Sclerosis | Alzheimer Disease | Lewy Body Disease | Multiple System Atrophy | Corticobasal Degeneration | Frontotemporal Dementia | Vascular Dementia | Progressive Supranuclear Palsy | Huntington Disease

Finland
Avera McKennan Hospital & University Health Center
Sema4

Recruiting

Avera Cancer Sequencing and Analytics Protocol (ASAP) (ASAP)

Cancer | Breast Cancer | Gynecologic Cancer | Ovarian Cancer | Lung Cancer | Endometrial Cancer | Colon Cancer | CNS Cancer | GI Cancer | Hematologic Cancer | Early Detection of Cancer | Cancer Diagnosis

United States
MD Stem Cells

Recruiting

Neurologic Stem Cell Treatment Study (NEST)

Stroke | Nervous System Diseases | Diabetic Neuropathies | Neurodegenerative Diseases | Cognitive Impairment | Amyotrophic Lateral Sclerosis | Dementia | Neurological Disorders | Alzheimer Disease | ALS | Traumatic Brain Injury | Cerebral Infarction | Lewy Body Disease | Cerebral Hemorrhage | Frontotemporal Dementia | Progressive... and other conditions

United States, United Arab Emirates
Coordinación de Investigación en Salud, Mexico

Recruiting

Hypofractionated Radiation Therapy vs Standard Treatment in Breast Cancer.

Stage 0 Breast Cancer | Stage I Breast Cancer | Invasive Breast Cancer | Stage IA Breast Cancer | Stage IB Breast Cancer | Ductal Breast Carcinoma in Situ | Early-stage Breast Cancer

Mexico
Nova Scotia Health Authority

Recruiting

Lemborexant for Insomnia in a Patient With Dementia: An N-of-1 Trial

Insomnia | Dementia | Frontotemporal Dementia

Canada
Fakultas Kedokteran Universitas Indonesia

Unknown

Zinc Supplementation on Very Low Birth Weight Infant

Enterocolitis, Necrotizing | Retinopathy of Prematurity | Bronchopulmonary Dysplasia | Early-Onset Sepses, Neonatal | Small for Gestational Age Infant | Periventricular Haemorrhage Neonatal
Aarne Feldheiser
Technische Universität Berlin; Humboldt-Universität zu Berlin; German Institute... and other collaborators

Completed

Perioperative Early Tiredness (Acute Fatigue) in Patients With Epithelial Ovarian Cancer (PERISCOPE)

Nutrition | Mitochondrial Dysfunction | Electrical Cardiometry | Perioperative Early Tiredness (Acute Fatigue) | Biosignals

Germany
University of California, San Francisco

Completed

Mindfulness-Based Stress Reduction in Dementia Caregivers (MBSR)

Dementia | Frontotemporal Dementia | Frontotemporal Lobar Degeneration | Caregiver Stress Syndrome | Caregiver Burnout | Dementia Frontal | Mindfulness Based Stress Reduction

United States
University of Washington
National Institute on Aging (NIA)

Completed

Innovations in Dementia Empowerment and Action (IDEA)

Dementia | Alzheimer Disease | Mild Cognitive Impairment | Vascular Dementia | Lewy Body Dementia | Parkinson Disease Dementia

United States
Dana-Farber Cancer Institute
Novartis Pharmaceuticals

Completed

Phase Ib Study of BKM120 With Cisplatin and XRT in High Risk Locally Advanced Squamous Cell Cancer of Head and Neck

Hypopharyngeal Cancer | HPV Positive Oropharyngeal Squamous Cell Carcinoma | Carcinoma, Squamous Cell of Head and Neck | Early Invasive Cervical Squamous Cell Carcinoma | Cancer of Nasopharynx | Carcinoma of Larynx

United States
Axovant Sciences Ltd.

Terminated

Open-label Study of Nelotanserin in Lewy Body Dementia With Visual Hallucinations or REM Sleep Behavior Disorder

REM Sleep Behavior Disorder | Dementia With Lewy Bodies | Lewy Body Dementia | Parkinson's Disease Dementia | Visual Hallucinations

United States
Clionsky Neuro Systems Inc.

Completed

COMPARATIVE EFFECTIVENESS OF MCI and DEMENTIA TREATMENTS IN A COMMUNITY-BASED DEMENTIA PRACTICE

Brain Injuries | Hypoxia | Parkinson's Disease | Anemia | TDP-43 Proteinopathies | Dementia | Tauopathies | Mild Cognitive Impairment | Iron Deficiency | Vitamin B 12 Deficiency | Frontotemporal Dementia | Vascular Dementia | Alzheimer's Disease | Neurodegenerative Disorders | TBI | Lewy Body Dementia | Hyperhomocysteinemia
Simon Ducharme, MD
Alzheimer's Drug Discovery Foundation

Active, not recruiting

Nabilone for Agitation in Frontotemporal Dementia (Nabilone-FTD)

Frontotemporal Dementia | Primary Progressive Aphasia | Frontotemporal Dementia, Behavioral Variant | FTD | PPA | bvFTD

Canada
Université de Sherbrooke
Canadian Institutes of Health Research (CIHR); Western University, Canada; Agence...

Completed

Patient-Centred Innovations for Persons With Multimorbidity - Quebec (PACEinMM-QC)

Depression | Heart Failure | Stroke | Hypertension | Cardiovascular Disease | Diabetes | Ulcer | Cancer | Arthritis | Rheumatoid Arthritis | Musculoskeletal Pain | Asthma | Gastroesophageal Reflux | Dementia | Anxiety | HIV | Crohn's Disease | Osteoporosis | Ulcerative Colitis | Chronic Obstructive Pulmonary Disease (COPD) | Hyperlipi... and other conditions

Canada
Lawson Health Research Institute
University Health Network, Toronto; Sunnybrook Health Sciences Centre; Canadian... and other collaborators

Completed

Patient-Centred Innovations for Persons With Multimorbidity - Ontario (PACEinMM-ON)

Depression | Heart Failure | Stroke | Hypertension | Cardiovascular Disease | Diabetes | Ulcer | Cancer | Arthritis | Rheumatoid Arthritis | Musculoskeletal Pain | Asthma | Gastroesophageal Reflux | Dementia | Anxiety | HIV | Crohn's Disease | Osteoporosis | Ulcerative Colitis | Chronic Obstructive Pulmonary Disease (COPD) | Hyperlipi... and other conditions

Canada
SWOG Cancer Research Network
National Cancer Institute (NCI)

Active, not recruiting

S1702 Isatuximab in Treating Patients With Relapsed or Refractory Primary Amyloidosis

Nausea | Constipation | Diarrhea | Purpura | Lymphadenopathy | Gastrointestinal Hemorrhage | Hepatomegaly | Primary Systemic Amyloidosis | Amorphous, Eosinophilic, and Acellular Deposit | Early Satiety | Macroglossia | Recurrent Primary Amyloidosis | Refractory Primary Amyloidosis

United States
National Institute of Mental Health (NIMH)

Terminated

PET Evaluation of Brain Peripheral Benzodiazepine Receptors Using [11C]PBR28 in HIV-Seropositive Patients With (MCMD)

HIV Infections | Healthy | AIDS Dementia Complex | AIDS-Related Dementia Complex | HIV-Associated Cognitive Motor Complex | HIV-Dementia | AIDS Encephalopathy

United States
Willows Health
Nottingham Trent University

Not yet recruiting

Benchtop NMR Spectroscopy for Assessment of Clinical Human Pathologies (BRANCH-P STUDY) (BRANCH-P)

Depression | Heart Diseases | Cardiovascular Diseases | HIV Infections | Obesity | Diabetes | Cancer | Chronic Kidney Diseases | Arthritis | Bulimia | Alzheimer Disease | Cellulitis | Cirrhosis | Eczema | Osteoporosis | Appendicitis | Bronchitis | Bowel Disease | Gout | Alcoholic Liver Disease | Flu | High Cholesterol | Allergies | Indigestion | ... and other conditions

United Kingdom
National Cancer Institute (NCI)

Terminated

Retinoid 9cUAB30 in Producing a Biologic Effect in Patients With Early Stage Breast Cancer

Anatomic Stage I Breast Cancer AJCC v8 | Anatomic Stage IA Breast Cancer AJCC v8 | Anatomic Stage IB Breast Cancer AJCC v8 | Anatomic Stage II Breast Cancer AJCC v8 | Anatomic Stage IIA Breast Cancer AJCC v8 | Anatomic Stage IIB Breast Cancer AJCC v8 | Breast Ductal Carcinoma In Situ | Invasive Breast... and other conditions

United States
Duke University
University of Edinburgh in Scotland; Tan Tock Seng Hospital in Singapore; Queens...

Recruiting

Retinal Imaging in Neurodegenerative Disease

Multiple Sclerosis | Parkinson's Disease | Traumatic Brain Injury | Down Syndrome | Mild Cognitive Impairment | Frontotemporal Dementia | Huntington Disease | Amyotrophic Lateral Sclerosis (ALS) | Alzheimer's Disease | Concussion | Post-Traumatic Stress Disorder | Neuro-Degenerative Disease | Lewy Body Dementia | Normal... and other conditions

United States
Medipol University

Completed

Effect of Non-nutritive Sucking on Transition to Oral Feeding in Infants With Asphyxia

Perinatal Asphyxia | Hypoxic-Ischemic Encephalopathy | Swallowing Disorder | Feeding; Difficult, Newborn | Speech Therapy | Feeding Disorder of Infancy or Early Childhood

Turkey
City of Hope Medical Center
National Cancer Institute (NCI); Mustang Bio, Inc.

Active, not recruiting

Genetically Modified T-cell Immunotherapy in Treating Patients With Relapsed/Refractory Acute Myeloid Leukemia and Persistent/Recurrent Blastic Plasmacytoid Dendritic Cell Neoplasm

Acute Myeloid Leukemia | Recurrent Adult Acute Myeloid Leukemia | Secondary Acute Myeloid Leukemia | Untreated Adult Acute Myeloid Leukemia | Adult Acute Myeloid Leukemia in Remission | Refractory Acute Myeloid Leukemia | Blastic Plasmacytoid Dendritic Cell Neoplasm | Minimal Residual Disease | Acute... and other conditions

United States
Northwestern University
National Institute on Alcohol Abuse and Alcoholism (NIAAA); National Cancer... and other collaborators

Recruiting

Liver Cirrhosis Network Cohort Study (LCN-C)

Cirrhosis | Cirrhosis, Liver | Cirrhosis Due to Hepatitis B | Cirrhosis Due to Hepatitis C | Cirrhosis Early | Cirrhosis Advanced | Cirrhosis Infectious | Cirrhosis Alcoholic | Cirrhosis, Biliary | Cirrhosis Cryptogenic | Cirrhosis Due to Primary Sclerosing Cholangitis

United States
National Institute of Diabetes and Digestive and...
National Institute on Alcohol Abuse and Alcoholism (NIAAA); National Cancer... and other collaborators

Recruiting

Liver Cirrhosis Network Rosuvastatin Efficacy and Safety for Cirrhosis in the United States (LCN RESCU)

Cirrhosis | Cirrhosis, Liver | Cirrhosis Due to Hepatitis B | Cirrhosis Due to Hepatitis C | Cirrhosis Early | Cirrhosis Advanced | Cirrhosis Infectious | Cirrhosis Alcoholic | Cirrhosis, Biliary | Cirrhosis Cryptogenic | Cirrhosis Due to Primary Sclerosing Cholangitis

United States
DanceStream Projects
Alzheimer's Association

Recruiting

Stories in the Moment: Dance Program for People Living With Dementia

Dementia | Alzheimer Disease | Mild Cognitive Impairment | Lewy Body Disease | Frontotemporal Dementia | Vascular Dementia

United States
HealthMode Inc.

Completed

Feasibility of Passive Data Collection in Dementia Subjects With Agitation

Dementia | Alzheimer Disease | Frontotemporal Dementia | Vascular Dementia | Lewy Body Dementia | Mixed Dementia

United States
Johns Hopkins University
National Heart, Lung, and Blood Institute (NHLBI)

Enrolling by invitation

Derivation of Human Induced Pluripotent Stem (iPS) Cells to Heritable Cardiac Arrhythmias

Hypertrophic Cardiomyopathy (HCM) | Long QT Syndrome (LQTS) | Catecholaminergic Polymorphic Ventricular Tachycardia (CPVT) | Inherited Cardiac Arrythmias | Brugada Syndrome (BrS) | Early Repolarization Syndrome (ERS) | Arrhythmogenic Cardiomyopathy (AC, ARVD/C) | Dilated Cardiomyopathy (DCM) | Muscular... and other conditions

United States
Centre Hospitalier Universitaire, Amiens

Completed

Evaluation and Characterization of Behavioural Disorders and Dementias by the Behavioural Dysexecutive Syndrome Inventory (BDSI) (ISDC)

Alzheimer Disease | Frontotemporal Dementia | Dementia, Vascular | Semantic Dementia | Huntington Disease

France
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Active, not recruiting

Hypofractionated Partial Breast Irradiation in Treating Patients With Early Stage Breast Cancer

Invasive Breast Carcinoma | Early-Stage Breast Carcinoma | Stage I Breast Cancer AJCC v7 | Stage IA Breast Cancer AJCC v7 | Stage IB Breast Cancer AJCC v7 | Stage II Breast Cancer AJCC v6 and v7 | Stage IIA Breast Cancer AJCC v6 and v7 | Stage IIB Breast Cancer AJCC v6 and v7 | Ductal Breast Carcinoma... and other conditions

United States
University of Rostock
German Center for Neurodegenerative Diseases (DZNE); Fraunhofer Institute

Completed

SAMi Intervention Study to Evaluate Smartwatch Interventions in Persons With MCI and Dementia (SAIN_UMR)

Dementia | Alzheimer Disease | Mild Cognitive Impairment | Dementia, Vascular | Dementia, Mixed | Dementia With Lewy Bodies | Dementia Frontotemporal

Germany
University of Pittsburgh

Recruiting

Longitudinal Study of Neurodegenerative Disorders

Lysosomal Storage Diseases | Leukodystrophy | Niemann-Pick Diseases | Batten Disease | Gaucher Disease | Krabbe Disease | Alpha-Mannosidosis | Osteopetrosis | Tay-Sachs Disease | Pelizaeus-Merzbacher Disease | Sandhoff Disease | GM1 Gangliosidoses | MPS I | MPS II | Vanishing White Matter Disease | Multiple Sulfatase Deficiency... and other conditions

United States
Foundation Fighting Blindness

Recruiting

Inherited Retinal Degenerative Disease Registry (MRTR)

Retinitis Pigmentosa | Choroideremia | Usher Syndrome | Batten Disease | Leber Congenital Amaurosis | Goldmann-Favre Syndrome | Kearns-Sayre Syndrome | Retinal Disease | Bardet-Biedl Syndrome | Stargardt Disease | Cone Dystrophy | Retinoschisis | Achromatopsia | Gyrate Atrophy | Eye Diseases Hereditary | Bassen-Kornzweig... and other conditions

United States
University of Pennsylvania

Completed

The Music, Sleep and Dementia Study

Neurocognitive Disorders | Sleep Disorder | Insomnia | Cognitive Impairment | Dementia | Alzheimer Disease | Mild Cognitive Impairment | Frontotemporal Dementia | Vascular Dementia | Cognitive Decline | Memory Impairment | Circadian Rhythm Disorders | Hypersomnia | Circadian Rhythm Sleep Disorder

United States
University of Pennsylvania
Thomas Jefferson University; Drexel University

Completed

Care of Persons With Dementia in Their Environments (COPE) in Programs of All-Inclusive Care of the Elderly (PACE)

Neurocognitive Disorders | Dementia | Alzheimer Disease | Lewy Body Disease | Frontotemporal Dementia | Vascular Dementia | Mixed Dementia | Pick Disease | Multi-Infarct Dementia

United States

Clinical Trials on Early Alzheimer´s Disease

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