Clinical Trials on Enzyme Inhibitors
Total 517 results
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The University of Hong KongRecruitingRecurrent Glioblastoma | Recurrent Glioma | Poly ADP Ribose Polymerase (PARP) Inhibitor | PTEN Gene Inactivation | IDH MutationHong Kong
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University Health Network, TorontoNot yet recruitingEnd Stage Kidney Disease | Kidney Dysfunction | Peritoneal Dialysis Complication | Sodium-glucose Co-transporter-2 Inhibitors | Residual Kidney FunctionCanada
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Hangzhou Cancer HospitalUnknownNon-small Cell Lung Cancer | Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitor (EGFR-TKI)China
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Hunan Cancer HospitalRecruitingChemotherapy Effect | NK/T-cell Lymphoma of Nasal Cavity | Immune Checkpoint Inhibitor | Epigenetic DisorderChina
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Guangxi Medical UniversityWuzhou Red Cross Hospital; Wuhan Union Hospital, China; Yunnan Cancer Hospital; Hainan People's Hospital and other collaboratorsNot yet recruitingNasopharyngeal Carcinoma | Neoadjuvant Therapy | PD-1 Inhibitor
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National Taiwan University HospitalRecruitingPharmacokinetics | Therapeutic Drug Monitoring | Tyrosine Kinase InhibitorTaiwan
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Gene SolutionsRecruitingNon Small Cell Lung Cancer | Stage IIIB Non-small Cell Lung Cancer | Stage IV Non-small Cell Lung Cancer | Stage IIIC Non-Small Cell Lung Cancer | Tyrosine Kinase InhibitorsVietnam
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Peking Union Medical College HospitalRecruitingLung Cancer | Chemotherapy | Antibody | COVID-19 Recurrent | Vaccination | Immune Checkpoint InhibitorChina
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Peking Union Medical College HospitalNot yet recruitingNon Small Cell Lung Cancer | Immune Checkpoint Inhibitor | EGFR Exon 21 MutationChina
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Sun Yat-sen UniversityRecruitingMuscle-Invasive Bladder Carcinoma | Radiotherapy | Programmed Cell Death Protein 1 InhibitorChina
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Xiaoxiang ChenNot yet recruitingOvarian Cancer | HRD | PARP InhibitorChina
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Chinese PLA General HospitalUnknownAtherosclerosis Type 2 Diabetes Mellitus Dipeptidyl Peptidase-4 Inhibitor GLP-1
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Fudan UniversityUnknownNeoplasms | Immune System Diseases | Lymphoma, B-Cell | Lymphoma, Large B-Cell, Diffuse | Lymphoproliferative Disorders | Lymphatic Diseases | Immunoproliferative Disorders | Lymphoma, Non-Hodgkin | Gemcitabine | Cisplatin | Dexamethasone | Rituximab | Cyclophosphamide | Chidamide | Neoplasm by Histology | HDAC InhibitorChina
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Chulalongkorn UniversityRecruitingComparison of Outcomes Between Low Dose Emicizumab and Factor VIII in Clinically Severe Hemophilia AJoint Bleed | Severe Hemophilia A Without InhibitorThailand
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Tianjin Medical University Cancer Institute and...RecruitingCarcinoma, Non-Small-Cell Lung | EGF-R Positive Non-Small Cell Lung Cancer | Bevacizumab | Tyrosine Kinase InhibitorChina
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Daiichi Sankyo, Inc.PlexxikonTerminatedV600-mutated BRAF Unresectable Melanoma | V600-mutated BRAF Metastatic Melanoma | Stage III or Stage IV Metastatic Melanoma That Has Not Been Previously Treated With a Selective BRAF InhibitorUnited States, Germany, France
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University Hospital Inselspital, BerneRigshospitalet, Copenhagen, Denmark (Prof. Moller, Dr. Krag)CompletedCritical Illness | Acute Kidney Injury | Renal Replacement Therapy | End-stage Renal Disease | Proton Pump InhibitorDenmark, Switzerland
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Chongqing University Cancer HospitalNot yet recruitingPARP Inhibitor for Esophageal Squamous Cell Carcinoma
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CSL BehringCompletedCystic FibrosisBulgaria, Hungary, Poland, United Kingdom
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TakedaTakeda Development Center Americas, Inc.CompletedAngioedemaUnited States, Spain, Netherlands, Hungary, Italy, Canada, Germany, France, Japan, Poland
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Khon Kaen UniversityThai Rheumatism AssociationCompletedGastroesophageal Reflux | Systemic Sclerosis | Proton Pubm Inhibitor
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Oslo University HospitalCompletedHereditary Factor VIII Deficiency Disease With InhibitorNorway
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The University of Hong KongResearch Grant CouncilRecruitingCirrhosis | NAFLD | Chronic Hepatitis b | Fibrosis, Liver | Empagliflozin | SGLT2 InhibitorsHong Kong
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Jinling Hospital, ChinaRecruitingRenal Cell Carcinoma | Radiotherapy | Immune Checkpoint InhibitorChina
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Lei LiRecruitingCervical Carcinoma | Immunotherapy | Survival Outcomes | Adverse Events | Locally Advanced Cervical Cancer | Chemoradiotherapy | Immune Checkpoint Inhibitor | Anti-programmed Cell Death Receptor 1 | Early Stage Cervical CancerChina
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Xiaoxiang ChenRecruitingOvarian Cancer | PARP Inhibitor | Clinical MarkerChina
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CSL BehringCompletedEmphysema | Alpha1-proteinase Inhibitor DeficiencyAustralia, Russian Federation, United States, Denmark, Estonia, Finland, Germany, Ireland, Poland, Romania, Sweden, Canada, Czech Republic
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Zagazig UniversityUnknownHepatic Encephalopathy | Coenzyme Q10 | Intellectual Functioning DisabilityEgypt
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German Cancer Research CenterUniversity Hospital HeidelbergRecruitingPancreatic Cancer | Pancreatic Adenocarcinoma | CYP3A Inhibitor | Advanced Stage or Metastatic Pancreatic Ductal Adenocarcinoma | Pancreatic NeoplasmGermany
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Nanfang Hospital of Southern Medical UniversityPeking University People's Hospital; Guangzhou First People's Hospital; Sun Yat-Sen... and other collaboratorsUnknownAllogeneic Hematopoietic Stem Cell Transplantation | Minimal Residual Disease | Philadelphia Chromosome Positive Acute Lymphocytic Leukemia | Tyrosine Kinase InhibitorChina
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Shanghai Jiao Tong University School of MedicineCompletedOral Cancer | Induction Chemotherapy | Programmed Cell Death 1 Inhibitor | Inductive TherapyChina
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Stanley Jordan, MDCSL BehringCompletedKidney TransplantationUnited States
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Pharming Technologies B.V.University of Wisconsin, MadisonWithdrawnKidney Transplantation | Graft RejectionUnited States
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Sun Yat-Sen Memorial Hospital of Sun Yat-Sen UniversityNot yet recruitingPremenopausal Breast Cancer | Hormone-receptor-positive Breast Cancer | Breast Cancer Patients at Intermediate to High Risk | Ovarian Function Suppression Combined With Aromatase Inhibitor or Tamoxifen or TorimefenChina
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St George's, University of LondonRecruitingChronic Kidney Diseases | Heart Failure With Reduced Ejection Fraction | Hyperkalemia | ACE Inhibitor Induced Hyperkalaemia | Mineralocorticoid Resistant HyperkalemiaUnited Kingdom
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ShireTakeda Development Center Americas, Inc.CompletedAngioedemaUnited States, France, Netherlands, Spain, Hungary, Italy, Canada, Poland, Japan, Germany
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Spark TherapeuticsCompletedHematologic Diseases | Blood Coagulation Disorders, Inherited | Coagulation Protein Disorders | Hemorrhagic Disorders | Genetic Diseases, Inborn | Genetic Diseases, X-Linked | Gene Therapy | Blood Coagulation Disorder | Gene Transfer | Adeno-Associated Virus (AAV) | Factor VIII (FVIII) | Factor VIII (FVIII)... and other conditionsUnited States
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Algemeen Ziekenhuis Maria MiddelaresRecruitingCancer | Atherosclerosis | Cardiotoxicity | Diastolic Dysfunction | Immune Checkpoint Inhibitor-Related Myocarditis | Immune-related Adverse Event | Cardiac Abnormalities, VariableBelgium
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Amsterdam UMC, location VUmcCompletedType 2 Diabetes Mellitus | Diabetic Nephropathy | Diabetic Kidney Disease | Renal Hypoxia | Renoprotection | SGLT2 Inhibitor | ErtugliflozinNetherlands
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Institut Cancerologie de l'OuestActive, not recruitingMelanoma | Renal Cell Carcinoma | Head and Neck Cancer | Advanced Non-small Cell Lung Cancer | Immune Checkpoint Inhibitors | Therapeutic Patient Education | Immune-related Adverse EventFrance
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Wenjun ChengNot yet recruitingNeoplasms by Histologic Type | Neoplasms by Site | Carcinoma | Neoplasms, Glandular and Epithelial | Genital Neoplasms, Female | Endocrine System Diseases | Ovarian Diseases | Ovarian Neoplasms | Fallopian Tube Neoplasms | Carcinoma, Ovarian Epithelial | Angiogenesis | Genital Diseases, Female | Antineoplastic... and other conditions
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The Cleveland ClinicRecruitingCardiovascular Diseases | Breast Cancer | Cardiotoxicity | Hematologic Malignancy | Immune Checkpoint Inhibitor-Related MyocarditisUnited States
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Grifols Therapeutics LLCTerminatedCOVID-19United States, Brazil, Chile, Colombia, Mexico
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Catalyst BiosciencesTerminatedFactor VII Deficiency | Hemophilia A With Inhibitor | Glanzmann ThrombastheniaUnited States, India, Italy, Russian Federation, Ukraine
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Xiaoxiang ChenRecruitingNeoplasms | Neoplasms by Histologic Type | Urogenital Neoplasms | Neoplasms by Site | Carcinoma | Neoplasms, Glandular and Epithelial | Genital Neoplasms, Female | Ovarian Diseases | Adnexal Diseases | Carcinoma, Ovarian Epithelial | Ovarian Cancer | Angiogenesis | Genital Diseases, Female | Antineoplastic Agents | BRCA1... and other conditionsChina
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Hospital Universitari Vall d'Hebron Research InstituteHospital Universitario La PazNot yet recruitingHereditary Angioedema With C1 Esterase Inhibitor DeficiencySpain
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University Hospital, CaenCompletedChronic Myeloid Leukemia | Withdrawal Syndrome | Tyrosine Kinase InhibitorFrance
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Hospital Universitari Vall d'Hebron Research InstituteERN-EuroBloodNet (European Reference Network on Rare Hematological DiseasesRecruitingLeukemia | Anemia | Iron Metabolism Disorders | Anemia, Sickle Cell | Thalassemia | Bleeding Disorder | Myeloma | Lymphoid Neoplasm | Blood Cancer | Bone Marrow Failure | Red Cell Membrane and Enzyme Abnormalities | Myeloma, MalignantSpain
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Samsung Medical CenterActive, not recruitingNon-Small Cell Lung Cancer With EGFR T790M Mutation | With Brain and/or Leptomeningeal Metastasis | Failed Tyrosine Kinase InhibitorsKorea, Republic of
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Lei LiRecruitingEpithelial Ovarian Cancer | Homologous Recombination Deficiency | Homologous Recombination Repair Gene Mutation | Drug Resistance | Overall Survival | Progression-free Survival | Poly(ADP-ribose) Polymerase InhibitorChina