Clinical Trials on Epilepsy Syndrome

Total 35594 results

Lars Bo Andersen

Unknown

Physical Exercise in Subjects With Juvenile Myoclonic Epilepsy (EFA)

Epilepsy | Seizure Disorder | Epileptic Seizures | Epilepsia

Denmark
Universiteit Antwerpen
Universitaire Ziekenhuizen KU Leuven; KU Leuven; University Hospital, Antwerp; Research...

Completed

Treatment of Gait Disorders in Children With Dravet Syndrome (T-GaiD)

Dravet Syndrome | Severe Myoclonic Epilepsy of Infancy

Belgium
Northwell Health
Medtronic

Terminated

Long-term Cardiac Monitoring in Epilepsy (LOOP)

Generalized Epilepsy | Intractable Epilepsy | Focal Epilepsy | Epileptic Encephalopathy | Lennox Gastaut Syndrome | Symptomatic Epilepsy

United States
Maastricht University Medical Center
Epilepsiecentrum Kempenhaeghe

Completed

The Rolandic Epilepsy/ESES/Landau-Kleffner Syndrome and Correlation With Language Impairment Study (REL)

Rolandic Epilepsy | Landau-Kleffner Syndrome | Nocturnal Frontal Lobe Epilepsy | Electrical Status Epilepticus During Slow Wave Sleep

Netherlands
University Health Network, Toronto
Zogenix, Inc.

Not yet recruiting

Fenfluramine for Adult Dravet Patients

Dravet Syndrome | Dravet Syndrome, Intractable

Canada
Eisai Inc.

Available

Extended Access Program With Lorcaserin For The Treatment of Dravet Syndrome and Other Refractory Epilepsies

Epilepsies, Myoclonic | Drug Resistant Epilepsy
Takeda

Completed

A Study of Soticlestat as an Add-on Therapy in Children and Young Adults With Dravet Syndrome

Dravet Syndrome (DS)

China, Canada, France, Hungary, Poland, United States, Spain, Greece, Australia, Brazil, Serbia, Germany, Italy, Japan, Latvia, Netherlands, Ukraine, Russian Federation
UCB BIOSCIENCES, Inc.

Recruiting

A Study to Evaluate Safety, Tolerability, and Pharmacokinetics of Fenfluramine (Hydrochloride) in Infants 1 Year to Less Than 2 Years of Age With Dravet Syndrome (ORCHID)

Dravet Syndrome

United States, United Kingdom
Cook Children's Health Care System
Encoded Therapeutics

Recruiting

GABA Biomarkers in Dravet Syndrome

Dravet Syndrome

United States
Hospices Civils de Lyon

Recruiting

Neurodevelopmental Impact of Epilepsy on Autonomic Function in Dravet Syndrome (AUTONOMIC)

Epilepsy | Dravet Syndrome

Belgium, France, Germany
Stoke Therapeutics, Inc

Enrolling by invitation

An Open-Label Extension Study of STK-001 for Patients With Dravet Syndrome

Dravet Syndrome

United States
Fondation Ophtalmologique Adolphe de Rothschild

Completed

Neuronal Excitability of HCN1 Channel Mutations in Dravet Syndrome (EXCIDRAH)

Dravet Syndrome

France
Jazz Pharmaceuticals

Completed

Antiepileptic Efficacy Study of GWP42003-P in Children and Young Adults With Dravet Syndrome (GWPCARE1)

Epilepsy | Dravet Syndrome

France, United States, United Kingdom, Poland
INSYS Therapeutics Inc

Withdrawn

Cannabidiol Oral Solution as an Adjunctive Therapy for Treatment of Participants With Inadequately Controlled Dravet Syndrome

Dravet Syndrome
Encoded Therapeutics

Recruiting

A Clinical Study to Evaluate the Safety and Efficacy of ETX101, an AAV9-Delivered Gene Therapy in Children With SCN1A-positive Dravet Syndrome (UK Only)

Dravet Syndrome

United Kingdom
Boston Children's Hospital
Encoded Therapeutics

Recruiting

Transcranial Magnetic Stimulation to Measure Cortical Excitability in Dravet Syndrome

Dravet Syndrome

United States
Stoke Therapeutics, Inc

Completed

An Open-Label Study to Investigate the Safety of Single and Multiple Ascending Doses in Children and Adolescents With Dravet Syndrome

Dravet Syndrome

United States
Fondazione Policlinico Universitario Agostino Gemelli...
IRCCS San Raffaele

Enrolling by invitation

EXploring novEl Molecular Determinants of DRAvet Syndrome Phenotype Heterogeneity (EXEDRA)

Dravet Syndrome

Italy
Zogenix International Limited, Inc., a subsidiary...

Completed

An Open-Label Extension Trial to Assess the Long-Term Safety of ZX008 (Fenfluramine Hydrochloride HCl) Oral Solution in Children and Young Adults With Dravet Syndrome

Dravet Syndrome

United States, United Kingdom, Spain, Belgium, Italy, Australia, Denmark, Germany, Canada, Japan, Netherlands, France
Gillette Children's Specialty Healthcare
Mayo Clinic; Dartmouth-Hitchcock Medical Center; Ann & Robert H Lurie Children...

Completed

Verapamil as Therapy for Children and Young Adults With Dravet Syndrome

Dravet Syndrome

United States
University of California, Los Angeles

Available

Treatment of Dravet Syndrome With Fenfluramine (Expanded Access Protocol) (Dravet)

Dravet Syndrome

United States
Encoded Therapeutics

Recruiting

A Clinical Study to Evaluate the Safety and Efficacy of ETX101, an AAV9-Delivered Gene Therapy in Children With SCN1A-positive Dravet Syndrome (Australia Only)

Dravet Syndrome

Australia
Encoded Therapeutics

Recruiting

A Clinical Study to Evaluate the Safety and Efficacy of ETX101 in Infants and Children With SCN1A-Positive Dravet Syndrome (ENDEAVOR)

Dravet Syndrome

United States
Epygenix
Forest Hills Lab; Liberyx Therapeutics

Recruiting

EPX-100 (Clemizole Hydrochloride) as Add-on Therapy to Control Convulsive Seizures in Patients With Dravet Syndrome (ARGUS)

Dravet Syndrome

United States, Canada, Spain, Georgia, Hungary
Zogenix, Inc.

Approved for marketing

ZX008 Expanded Access Protocol

Dravet Syndrome
Zogenix International Limited, Inc., a subsidiary...

Completed

A 2-Part Study to Investigate the Dose-Ranging Safety and Pharmacokinetics, Followed by the Efficacy and Safety of ZX008 (Fenfluramine Hydrochloride) Oral Solution as an Adjunctive Therapy in Children ≥ 2 Years Old and Young Adults With Dravet Syndrome

Dravet Syndrome

United States, France, United Kingdom, Canada, Germany, Netherlands, Spain
Jazz Pharmaceuticals

Completed

A Dose-ranging Pharmacokinetics and Safety Study of GWP42003-P in Children With Dravet Syndrome (GWPCARE1)

Epilepsy | Dravet Syndrome

United States, United Kingdom
Jazz Pharmaceuticals

Completed

GWPCARE2 A Study to Investigate the Efficacy and Safety of Cannabidiol (GWP42003-P) in Children and Young Adults With Dravet Syndrome

Epilepsy | Dravet Syndrome

United States, Spain, Israel, Poland, Australia, Netherlands
University of Colorado, Denver

No longer available

Compassionate Use of Stiripentol in Dravet Syndrome

Dravet Syndrome

United States
Children's Hospital Medical Center, Cincinnati

Approved for marketing

Treatment Plan to Provide Expanded Access to Stiripentol for Patients With Dravet Syndrome

Dravet Syndrome

United States
H. Lundbeck A/S

Terminated

Safety and Tolerability of Clobazam as Adjunctive Therapy in Paediatric Patients Aged ≥1 to ≤16 Years With Dravet Syndrome

Dravet Syndrome

United States, Mexico
H. Lundbeck A/S

Withdrawn

Clobazam as Adjunctive Therapy in Paediatric Patients Aged ≥1 to ≤16 Years With Dravet Syndrome

Dravet Syndrome

United States, Mexico
Mayo Clinic

No longer available

Stiripentol in Dravet Syndrome

Dravet Syndrome

United States
Assistance Publique - Hôpitaux de Paris
Orphelia Pharma

Not yet recruiting

Multicentre Real-life Follow-up Study of Rare Epileptic Syndromes in Children and Adolescents (EPIRARE)

Epilepsy | Dravet Syndrome | West Syndrome

France
All India Institute of Medical Sciences, New Delhi

Recruiting

Cortical Excitability in West Syndrome Using Transcranial Magnetic Stimulation

West Syndrome

India
University Hospital, Montpellier

Completed

Cognitive Impairments in Children With Epilepsy

Epilepsy Syndrome

France
UCB Pharma

Completed

A Study to Investigate the Safety and Efficacy of Lacosamide Added to the Patients Current Therapy in Patients Aged 1 Month to Less Than 18 Years Old With Epilepsy Syndromes Associated With Generalized Seizures.

Epilepsy

United States, France, Hungary, Mexico, Poland
Ann & Robert H Lurie Children's Hospital of Chicago
Thrasher Research Fund

Unknown

Prevention of West Syndrome With Low-dose Adrenocorticotropin Hormone (ACTH) (PREVENT-WS)

West Syndrome

United States
Zogenix International Limited, Inc., a subsidiary...

Terminated

A Study to Assess the Usability of the Embrace Seizure Detection Watch in Children and Young Adults With Dravet Syndrome

Dravet Syndrome

United States
Eisai Inc.

Recruiting

A Study of Lorcaserin as Adjunctive Treatment in Participants With Dravet Syndrome (MOMENTUM 1)

Epilepsies, Myoclonic

United States, Canada
NYU Langone Health
PTC Therapeutics

Completed

Ataluren for Nonsense Mutation in CDKL5 and Dravet Syndrome

Epilepsy

United States
Biocodex

Recruiting

Retrospective Non-interventional Study of Stiripentol Use in Dravet Patients in the USA

Dravet Syndrome

United States
Epygenix

Completed

Study of Safety and Pharmacokinetics of Oral Doses of EPX-100 in Healthy Subjects.

Dravet Syndrome

United States
University of Colorado, Denver
Denver Health Medical Center

Completed

Genetic Analysis Between Charlotte's Web Responders Versus Non- Responders in a Dravet Population

Dravet Syndrome

United States
Second Affiliated Hospital, School of Medicine,...

Recruiting

Idiopathic Generalized Epilepsy Syndromes

Epilepsy | Epilepsy, Idiopathic Generalized

China
Zogenix International Limited, Inc., a subsidiary...

Completed

A Trial of Two Fixed Doses of ZX008 (Fenfluramine HCl) in Children and Young Adults With Dravet Syndrome

Dravet Syndrome | Seizure Disorder

United States, United Kingdom, Australia, Belgium, Canada, Denmark, France, Germany, Italy, Japan, Spain
Encoded Therapeutics

Terminated

Natural History Study of Infants and Children With Developmental and Epileptic Encephalopathies (ENVISION)

Dravet Syndrome

United States, Spain, Australia, United Kingdom
Erasmus Medical Center
Nationaal Epilepsie Fonds

Completed

Antibodies Causing Epilepsy Syndromes: The ACES Study. (ACES)

Epilepsy | Auto-immune Encephalitis

Netherlands
University of Oxford
Zogenix International Limited, Inc., a subsidiary of Zogenix, Inc.

Withdrawn

LEONIDaS Caregivers Study (LEONIDaS)

Depression | Anxiety | Dravet Syndrome
Boston Children's Hospital

Recruiting

Genetics of Epilepsy and Related Disorders

Epilepsy | Dravet Syndrome | Infantile Spasms | Epileptic Encephalopathy | Ohtahara Syndrome | Early Myoclonic Epileptic Encephalopathy | PCDH19-related Epilepsy and Related Conditions | KCNQ2-Related Epileptic Encephalopathy | Epilepsy of Infancy With Migrating Focal Seizures (Disorder)

United States

Clinical Trials on Epilepsy Syndrome

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Medical Conditions

Drug Interventions

CROs by country

CROs in Japan

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