Clinical Trials on Esophageal Reflux

Total 4870 results

Cancer Research UK
Heptares Therapeutics Limited

Recruiting

HTL0039732 in Participants With Advanced Solid Tumours

Sarcoma | Neoplasms | Kidney Neoplasms | Uterine Cervical Neoplasms | Stomach Neoplasms | Head and Neck Neoplasms | Lung Neoplasms | Urinary Bladder Neoplasms | Colorectal Neoplasms | Pancreatic Neoplasms | Esophageal Neoplasms | Mesothelioma, Malignant | Prostatic Neoplasms, Castration-Resistant | Pheochromocytomas

United Kingdom
Seagen Inc.

Terminated

A Study of SGN-STNV in Advanced Solid Tumors

Uterine Cervical Neoplasms | Stomach Neoplasms | Colorectal Neoplasms | Esophageal Neoplasms | Ovarian Neoplasms | Endometrial Neoplasms | Pseudomyxoma Peritonei | Carcinoma, Non-Small Cell Lung | Gastroesophageal Junction Carcinoma | HER2 Negative Breast Neoplasms | Exocrine Pancreatic Adenocarcinoma | Appendiceal...

United States, United Kingdom, Canada, Spain, France, Italy
City of Hope Medical Center
National Cancer Institute (NCI)

Completed

IRX-2, Cyclophosphamide, and Pembrolizumab in Treating Participants With Recurrent or Metastatic Gastric or Gastroesophageal Junction Cancer

Clinical Stage IV Gastric Cancer AJCC v8 | Clinical Stage IV Gastroesophageal Junction Adenocarcinoma AJCC v8 | Metastatic Gastric Adenocarcinoma | Metastatic Gastroesophageal Junction Adenocarcinoma | Postneoadjuvant Therapy Stage IV Gastroesophageal Junction Adenocarcinoma AJCC v8 | Postneoadjuvant... and other conditions

United States
Vanderbilt University Medical Center

Not yet recruiting

Voice and Swallowing Disorders in Adults With and Without Alzheimer's Disease

Alzheimer Disease | Caregiver Burden | Dysphagia | Healthy Aging | Dysphonia
Seattle Children's Hospital
Allen Institute

Not yet recruiting

Seattle Spatial Transcriptomic Research in Inflammatory Bowel Disease Evaluation (STRIDE) (STRIDE)

Inflammatory Bowel Diseases | Esophageal Diseases | Gallbladder Diseases | Crohn Disease | Ulcerative Colitis | Sphincter of Oddi Dysfunction | Anorectal Disorder | Bowel Dysfunction | Indeterminate Colitis | Functional Abdominal Pain Syndrome | Functional Bowel Disorder | Gastroduodenal Disorder

United States
Sohag University

Recruiting

Feeding and Swallowing Problems in Infants With Laryngomalacia

Swallowing Disorder | Feeding Disorders | Laryngomalacia

Egypt
NGM Biopharmaceuticals, Inc

Active, not recruiting

Study of NGM120 in Subjects With Advanced Solid Tumors, Pancreatic Cancer, and Prostate Cancer Using Combination Therapy

Melanoma | Gastric Cancer | Colorectal Cancer | Pancreatic Cancer | Esophageal Cancer | Ovarian Cancer | Prostate Cancer | Bladder Cancer | Non-small Cell Lung Cancer | Metastatic Castration-resistant Prostate Cancer | Head Neck Squamous Cell Carcinoma

United States
University Hospital, Bordeaux

Completed

A New Membrane Obturator Prothesis Concept for Soft Palate Defects (VELOMEMBRANE)

Deglutition Disorders | Speech Disorders | Mouth Neoplasms | Velopharyngeal Insufficiency

France
Tel-Aviv Sourasky Medical Center

Unknown

Applying PET/MR in Oncology - a Prospective Project

Sarcoma | Lymphoma | Cervical Cancer | Nasopharyngeal Cancer | Pancreatic Cancer | Esophageal Cancer | Prostate Cancer | Hepatobiliary Cancer
Duke University
Pfizer

Completed

Pillars4Life Trial (Pillars4Life)

Cervical Cancer | Breast Cancer | Pancreatic Cancer | Esophageal Cancer | Ovarian Cancer | Lung Cancer | Prostate Cancer | Bladder Cancer | Colon Cancer | Renal Cancer | Liver Cancer | Uterine Cancer

United States
University of Aarhus

Not yet recruiting

Dysphagia and Quality of Life in Patients With Oral Squamous Cell Carcinoma Before and After Treatment

Quality of Life | Dysphagia | Oral Cavity Cancer

Denmark
Eutilex

Recruiting

A Multi-center, Single-arm, Open, Phase I/IIa Clinical Trial to Evaluate the Efficacy and Safety of EBViNT Cell (EBV Specific Autologous CD8+ T Cell) in Patients With Treatment Failed Epstein Barr Virus (EBV)-Positive Malignancies

EBV Associated Extranodal NK/T-cell Lymphoma | EBV-Associated GastricCarcinoma or Esophageal AdenoCarcinoma

Korea, Republic of
Shandong Cancer Hospital and Institute

Completed

The Use of 18F-ALF-NOTA-PRGD2 PET/CT Scan to Predict the Efficacy and Adverse Events of Apatinib in Malignancies.

Cervical Cancer | Stomach Cancer | Breast Cancer | Esophageal Cancer | Non-small Cell Lung Cancer | Ovary Cancer | Malignancies

China
University Hospital, Lille
France Parkinson Association

Completed

Study of Dysarthria, Swallowing Disorders and Respiratory in Parkinson's Disease (ProdDiGYPark)

Parkinson's Disease

France
Hospital de Clinicas de Porto Alegre

Completed

Benefit From the Chin Down Maneuver in the Swallowing Performance and Self-perception of Parkinson's Disease Patients

Parkinson Disease | Speech Therapy | Orientation | Dysphagia, Oropharyngeal
University of Cincinnati
Children's Hospital Medical Center, Cincinnati

Terminated

Study of Bile Acids in Patients With Peroxisomal Disorders

Adrenoleukodystrophy | Zellweger Syndrome | Infantile Refsum's Disease | Bifunctional Enzyme Deficiency
Incyte Corporation

Active, not recruiting

Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of INCB099318 in Participants With Advanced Solid Tumors

Cervical Cancer | Nasopharyngeal Carcinoma | Advanced Solid Tumors | Mesothelioma | Small-cell Lung Cancer | Esophageal Squamous Cell Carcinoma | Merkel Cell Carcinoma | Sarcomatoid Renal Cell Carcinoma | Anal Carcinoma | Cutaneous Squamous Cell Carcinoma | MSI-H/dMMR Tumors | PD-L1 Amplified Tumor (9p24.1) | Urothelial... and other conditions

Finland, United States, United Kingdom, Belgium, Sweden, Denmark, Norway
VA Office of Research and Development
University of Pennsylvania; Walter Reed National Military Medical Center; Brooke...

Completed

Regional Anesthesia Military Battlefield Pain Outcomes Study (RAMBPOS)

Anxiety Disorders | Substance Abuse | Post-Traumatic Stress Disorder | Depressive Disorders | Complex Regional Pain Syndrome Type II

United States
Boston Children's Hospital

Completed

Offset Analgesia as a Measure of Central Sensitization in Children

CRPS (Complex Regional Pain Syndromes) | Chronic Pain Syndrome | Musculoskeletal Pain Disorder | Chronic Daily Headache | Functional Abdominal Pain Syndrome

United States
University of Erlangen-Nürnberg Medical School

Recruiting

Clinical Benefit and Biomarker Analysis of Combination of PD-1/PD-L1 Immune Checkpoint Inhibitors and Radiotherapy (ST-ICI02)

Renal Cell Carcinoma | Esophageal Cancer | NSCLC | Urothelial Carcinoma | HNSCC | Squamous Cell Carcinoma of the Skin | Small Cell Bronchial Carcinomas

Germany
University Health Network, Toronto
University of Florida; National Institute on Deafness and Other Communication...

Completed

Physiological Flow of Liquids Used in Dysphagia Management (Neuro)

Parkinson Disease | Amyotrophic Lateral Sclerosis | Dysphagia

United States
Institut für Klinische Krebsforschung IKF GmbH...

Recruiting

The PLATON Network (PLATON)

Stomach Cancer | Pancreatic Cancer | Cholangiocarcinoma | Gallbladder Cancer | Hepatocellular Cancer | Oesophageal Cancer

Germany
Charite University, Berlin, Germany

Recruiting

Online Adaptive Radiotherapy Using a Novel Linear Accelerator (ETHOS) (ART-02)

Head and Neck Cancer | Esophageal Cancer | NSCLC | Prostate Cancer | SCLC | Bladder Cancer | Cervix Cancer | Rectum Cancer | Other Carcinoma

Germany
European Organisation for Research and Treatment...
Anticancer Fund, Belgium; Rising Tide Foundation

Recruiting

Stereotactic Body Radiotherapy in Patients With Rare Oligometastatic Cancers (OligoRARE) (OligoRARE)

Melanoma | Sarcoma | Head and Neck Cancer | Gynecologic Cancer | Gastric Cancer | Pancreatic Cancer | Esophageal Cancer | Small Bowel Cancer | Bladder Cancer | Skin Cancer | Colon Cancer | Renal Cancer | Oligometastasis | Hepatobiliary Cancer | Upper Urinary Tract Carcinoma

Italy, France, Belgium, Switzerland, United Kingdom, Poland, Germany
McMaster University
Joseph Brant Hospital

Completed

The Effects of Whole-body Exercise to Improve Swallowing Function in Older Adults With Dementia

Parkinson Disease | Cough | Neuro-Degenerative Disease | Swallowing Disorder | Old Age; Dementia

Canada
Incyte Corporation

Terminated

An Open-Label Safety and Tolerability Study of INCB062079 in Subjects With Advanced Hepatocellular Carcinoma and Other Malignancies

Nasopharyngeal Cancer | Esophageal Cancer | Ovarian Cancer | Hepatocellular Carcinoma (HCC) | Cholangiocarcinoma | Solid Tumors

United States, Belgium
Eli Lilly and Company

Completed

A Study in Ovarian, Non-Small Cell Lung, Prostate, Colorectal, Gastroesophageal Cancers, and Squamous Cell Carcinoma of the Head and Neck

Gastric Cancer | Colorectal Cancer | Esophageal Cancer | Ovarian Cancer | Prostate Cancer | Non Small Cell Lung Cancer | Cancer of Head and Neck

United States
University of California, San Francisco
National Institute of Neurological Disorders and Stroke (NINDS)

Recruiting

Closed-Loop Deep Brain Stimulation for Refractory Chronic Pain

Pain, Postoperative | Complex Regional Pain Syndromes | Spinal Cord Injuries | Nerve Injury | Post Herpetic Neuralgia | Post-Stroke Pain | Post Radiation Brain Injury | Post Radiation Plexopathy | Nerve Root Avulsion

United States
Institut für Klinische Krebsforschung IKF GmbH...
Roche Pharma AG

Recruiting

PLATON - Platform for Analyzing Targetable Tumor Mutations (Pilot-study) (PLATON)

Stomach Cancer | Pancreatic Cancer | Cholangiocarcinoma | Gallbladder Cancer | Hepatocellular Cancer | Oesophageal Cancer

Germany
National Cancer Institute (NCI)

Active, not recruiting

Targeted Therapy Directed by Genetic Testing in Treating Patients With Advanced Refractory Solid Tumors, Lymphomas, or Multiple Myeloma (The MATCH Screening Trial)

Glioma | Hematopoietic and Lymphoid Cell Neoplasm | Melanoma | Lymphoma | Multiple Myeloma | Recurrent Ovarian Carcinoma | Breast Carcinoma | Recurrent Head and Neck Carcinoma | Recurrent Lung Carcinoma | Recurrent Skin Carcinoma | Gastric Carcinoma | Advanced Lymphoma | Advanced Malignant Solid Neoplasm | Refractory... and other conditions

United States, Puerto Rico, Guam
Quadriga Biosciences, Inc.
Novotech (Australia) Pty Limited

Completed

Dose Escalation Study to Assess the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of QBS10072S

Melanoma | Sarcoma | Kidney Cancer | Cervical Cancer | Breast Cancer | Head and Neck Cancer | Astrocytoma | Gastric Cancer | Colorectal Cancer | Pancreatic Cancer | Ovarian Cancer | Thymic Carcinoma | Lung Cancer | Prostate Cancer | Brain Cancer | Cholangiocarcinoma | Bladder Cancer | Liver Cancer | Brain Metastases | Tongue Cancer | Esophagus... and other conditions

Australia
University of California, San Diego

Completed

No Post Intubation Laryngeal Symptoms (No-PILS)

Dysphagia | Anesthesia Morbidity | Intubation Complication | Anesthesia Intubation Complication | Dysphonia | Anesthesia; Reaction | Anesthesia Complication | Anesthesia; Adverse Effect | Sore-throat | Throat Disorder | Throat; Wound | Throat Injury

United States
Queen Mary University of London

Unknown

Identification of Autoantigens in EGPA and Severe Eosinophilic Asthma (IDEA)

Eosinophilic Esophagitis | Churg-Strauss Syndrome | Eosinophilic Asthma | Eosinophilic Pneumonia

United Kingdom
Arkansas Children's Hospital Research Institute

Completed

Assessing Risk of Food Insecurity Within Households of Children With Food Allergy

Asthma | Allergic Rhinitis | Eosinophilic Esophagitis | Atopic Dermatitis | Food Allergy

United States
National Cancer Institute (NCI)

Active, not recruiting

Testing the Addition of an Anti-cancer Drug, BAY 1895344, to the Usual Chemotherapy Treatment (Cisplatin, or Cisplatin and Gemcitabine) for Advanced Solid Tumors With Emphasis on Urothelial Cancer

Anatomic Stage III Breast Cancer AJCC v8 | Anatomic Stage IV Breast Cancer AJCC v8 | Advanced Malignant Solid Neoplasm | Stage III Lung Cancer AJCC v8 | Stage IV Lung Cancer AJCC v8 | Clinical Stage III Gastric Cancer AJCC v8 | Clinical Stage IV Gastric Cancer AJCC v8 | Triple-Negative Breast Carcinoma and other conditions

United States, Canada
Duke University

Recruiting

Onco-primary Care Networking to Support TEAM-based Care (ONE TEAM)

Hypertension | Diabetes Mellitus | Diabetes | Cancer | Blood Pressure | Hypercholesterolemia | Non Small Cell Lung Cancer | Cancer of Head and Neck | Cancer of Liver | Cancer, Breast | Cancer of Pancreas | Cancer Colorectal | Cancer of Prostate | Cancer of Esophagus | Cancer, Endometrial | CVD - Cardiovascular Disease | Cancer... and other conditions

United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Active, not recruiting

Pembrolizumab and Chemoradiotherapy for the Treatment of Unresectable Gastroesophageal Cancer

Clinical Stage III Gastroesophageal Junction Adenocarcinoma AJCC v8 | Clinical Stage IV Gastroesophageal Junction Adenocarcinoma AJCC v8 | Unresectable Gastroesophageal Junction Adenocarcinoma | Locally Advanced Gastroesophageal Junction Adenocarcinoma | Postneoadjuvant Therapy Stage III... and other conditions

United States
University of California, San Francisco

Recruiting

Transcranial Magnetic Stimulation for Chronic Neuropathic Pain

Pain, Postoperative | Complex Regional Pain Syndromes | Spinal Cord Injuries | Nerve Injury | Trigeminal Neuralgia | Post-herpetic Neuralgia | Post-Stroke Pain | Nerve Root Avulsion | Chronic Neuropathic Pain

United States
Mirum Pharmaceuticals, Inc.
Children's Hospital Medical Center, Cincinnati

Completed

Compassionate Treatment of Patients With Inborn Errors of Bile Acid Metabolism With Cholic Acid

Cholestasis | Peroxisomal Disorders | Adrenoleukodystrophy | Zellweger Syndrome | Infantile Refsum's Disease

United States
Case Comprehensive Cancer Center

Not yet recruiting

EQUITY GI: A Prospective Study to Enhance Quality, Inclusivity, and Trial Participation in Black Patients With Gastrointestinal Cancer.

Stomach Cancer | Esophageal Cancer | Rectal Cancer | Neuroendocrine Tumors | Colon Cancer | Pancreas Cancer | Gastrointestinal Cancer | Anal Cancer | Liver Cancer | Appendix Cancer

United States
University Hospital, Antwerp
Kom Op Tegen Kanker; Stichting tegen Kanker

Recruiting

First-in-human Interleukin-15-transpresenting Wilms' Tumor Protein 1-targeting Autologous Dendritic Cell Vaccination in Cancer Patients (IL15-TransDC)

Esophageal Cancer | Ovarian Cancer | Pancreas Cancer | Liver Cancer

Belgium
Regeneron Pharmaceuticals

Available

Compassionate Use of Dupilumab

Bullous Pemphigoid | Pediatric Asthma | Pediatric Eosinophilic Esophagitis (EoE) | Pediatric and Adolescent Chronic Rhinosinusitis With Nasal Polyps (CRSwNP)
Rigshospitalet, Denmark

Active, not recruiting

Functional Outcome After Treatment for Oropharyngeal Squamous Cell Carcinoma

Quality of Life | Pain | Oropharynx Cancer | Human Papilloma Virus | Swallowing Disorder | Saliva Altered

Denmark
NYU Langone Health

Completed

Effect of Nasal Continuous Positive Airway Pressure on The Pharyngeal Swallow in Neonates

Respiratory Aspiration | Deglutition Disorders | Respiratory Distress Syndrome In Premature Infants | Newborn, Premature
Memorial Sloan Kettering Cancer Center

Completed

Study of D-Methadone in Patients With Chronic Pain

Pain | Breast Cancer | Head and Neck Cancer | Otorhinolaryngologic Neoplasms | Pancreatic Cancer | Esophageal Cancer | Prostate Cancer | Bladder Cancer | Colon Cancer | Uterine Cancer | CNS Cancer | Eye Cancer

United States
Labcorp Drug Development Inc

Recruiting

PRospective rEgistry OF Advanced Stage cancER (PREFER) Patients to Assess Prevalence of Actionable Biomarkers and Driver Mutations to Address Disparities in Precision Medicine (PREFER)

Melanoma | Soft Tissue Sarcoma | Stomach Cancer | Breast Cancer | Head and Neck Cancer | Colorectal Cancer | Pancreatic Cancer | Esophageal Cancer | Ovarian Cancer | Lung Cancer | Prostate Cancer | Rhabdomyosarcoma | Uterine Cancer

United States
Delfi Diagnostics Inc.

Recruiting

DNA Evaluation of Fragments for Early Interception - Lung Cancer Training Study (DELFI-L101 Study) (DELFI-L101)

Kidney Cancer | Stomach Cancer | Head and Neck Cancer | Colorectal Cancer | Esophageal Cancer | Lung Cancer | Bladder Cancer | Pancreas Cancer | Liver Cancer

United States
National Institute of Allergy and Infectious Diseases...

Recruiting

Natural History and Genetics of Food Allergy and Related Conditions

Eosinophilic Esophagitis | Atopic Dermatitis | Food Allergy | Loeys-Dietz Syndrome

United States
Exact Sciences Corporation

Completed

Blood Sample Collection to Evaluate Biomarkers in Subjects With Untreated Solid Tumors

Kidney Cancer | Stomach Cancer | Breast Cancer | Colorectal Cancer | Pancreatic Cancer | Esophageal Cancer | Ovarian Cancer | Lung Cancer | Prostate Cancer | Bladder Cancer | Liver Cancer | Renal Pelvis Cancer | Uterine Cancer

United States
Hospital de Clinicas de Porto Alegre

Completed

Cheeks Appearance as a Novel Predictor of Obstructive Sleep Apnea The CASA Score Study (CASA)

Muscle Weakness | Obstructive Sleep Apnea | Swallowing Disorder | Muscle Disorder | Face | Breathing, Sleep-Disordered

Brazil

Clinical Trials on Esophageal Reflux

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CROs in Estonia

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