Clinical Trials on Ewing's Sarcoma Metastatic

Total 11589 results

Institut Bergonié
Ipsen; MSD France

Recruiting

Combination of Pembrolizumab and Cabozantinib in Patients With Advanced Sarcomas (PEMBROCABOSARC)

Osteosarcoma | Ewing Sarcoma | Soft Tissue Sarcoma Adult | Undifferentiated Pleomorphic Sarcoma | Advanced Soft-tissue Sarcoma

France
Baylor College of Medicine
National Cancer Institute (NCI); Stand Up To Cancer; Center for Cell and Gene... and other collaborators

Recruiting

HER2 Chimeric Antigen Receptor (CAR) T Cells in Combination With Checkpoint Blockade in Patients With Advanced Sarcoma

Sarcoma | Soft Tissue Sarcoma | Osteosarcoma | Ewing Sarcoma | Rhabdomyosarcoma | Synovial Sarcoma | HER-2 Protein Overexpression | Undifferentiated Sarcoma

United States
OHSU Knight Cancer Institute
Novartis Pharmaceuticals; Oregon Health and Science University

Completed

Ribociclib and Doxorubicin in Treating Patients With Metastatic or Advanced Soft Tissue Sarcomas That Cannot Be Removed by Surgery

Stage III Soft Tissue Sarcoma AJCC v7 | Stage IV Soft Tissue Sarcoma AJCC v7 | Locally Advanced Leiomyosarcoma | Unresectable Leiomyosarcoma | Myxofibrosarcoma | Metastatic Malignant Peripheral Nerve Sheath Tumor | Metastatic Synovial Sarcoma | Metastatic Undifferentiated Pleomorphic Sarcoma | Unresectable... and other conditions

United States
Technical University of Munich

Unknown

Trabectedin and Irinotecan for Refractory Pediatric Sarcomas (TrIPReSarc)

Recurrent Ewing Sarcoma | Recurrent Rhabdomyosarcoma | Recurrent Childhood Soft Tissue Sarcoma
Sumitomo Pharma America, Inc.

Terminated

Phase 1, First-in-human Study of Oral TP-1287 in Patients With Advanced Solid Tumors

Sarcoma | Ewing Sarcoma | Advanced Solid Tumors | Synovial Sarcoma | Dedifferentiated Liposarcoma

United States
University College, London
Cancer Research UK; NCRI Radiotherapy Trials QA (RTTQA) Group

Completed

A Study of IMRT in Primary Bone and Soft Tissue Sarcoma (IMRiS)

Ewing Sarcoma | Chordoma | Bone Sarcoma | Soft Tissue Sarcoma, Adult

United Kingdom, Ireland
David Dickens

Withdrawn

Gemcitabine With Ascorbate Including Adolescents

Soft Tissue Sarcoma | Bone Sarcoma | Unresectable Soft Tissue Sarcoma | Metastatic Soft-tissue Sarcoma | Metastatic Bone Sarcoma | Unresectable Bone Sarcoma

United States
Anna Raciborska
Wroclaw Medical University

Recruiting

To Evaluate the Efficacy and Safety of Naxitamab in Patients With Refractory Ewing's Sarcoma (Butterfly)

Ewing Sarcoma

Poland
Peking University People's Hospital

Recruiting

Irinotecan and Temozolomide for Ewing Sarcoma

Ewing Sarcoma

China
Sarcoma Alliance for Research through Collaboration
National Cancer Institute (NCI); Janssen Scientific Affairs, LLC; National Institutes...

Active, not recruiting

SARC037: A Phase I/II Study to Evaluate the Safety of Trabectedin in Combination With Irinotecan in Ewing Sarcoma Patients (U01CA236220)

Ewing Sarcoma

United States
Eisai Inc.

Completed

Study to Assess Safety and Preliminary Activity of Eribulin Mesylate in Pediatric Participants With Relapsed/Refractory Rhabdomyosarcoma (RMS), Non-rhabdomyosarcoma Soft Tissue Sarcoma (NRSTS) and Ewing Sarcoma (EWS)

Ewing Sarcoma | Non-rhabdomyosarcoma Soft Tissue Sarcoma | Relapsed/Refractory Rhabdomyosarcoma

United States
National Cancer Institute (NCI)

Completed

Vincristine Sulfate, Topotecan Hydrochloride, and Cyclophosphamide With or Without Bevacizumab in Treating Young Patients With Refractory or First Recurrent Extracranial Ewing Sarcoma

Ewing Sarcoma of Bone | Peripheral Primitive Neuroectodermal Tumor | Recurrent Ewing Sarcoma/Peripheral Primitive Neuroectodermal Tumor | Extraosseous Ewing Sarcoma

United States
Oncolytics Biotech

Completed

Safety and Efficacy Study of REOLYSIN® in the Treatment of Bone and Soft Tissue Sarcomas Metastatic to the Lung

Osteosarcoma | Leiomyosarcoma | Fibrosarcoma | Sarcoma, Synovial | Ewing Sarcoma Family Tumors | Malignant Fibrous Histiocytoma

United States
University Hospital Tuebingen
Cooperative Weichteilsarkom Study Group; Deutsches Konsortium fürTranslationale... and other collaborators

Recruiting

Personalized Vaccination in Fusion+ Sarcoma Patients (PerVision) (PerVision)

Ewing Sarcoma | Rhabdomyosarcoma | Synovial Sarcoma

Germany
Mohammed M Milhem
Genentech, Inc.

Completed

Bevacizumab, Chemotherapy and Valproic Acid in Advanced Sarcomas

Sarcoma | Soft Tissue Sarcoma | Metastatic Sarcoma | Locally Advanced Sarcoma | Unresectable Sarcoma

United States
Children's Oncology Group
National Cancer Institute (NCI)

Completed

Cytarabine in Treating Young Patients With Recurrent or Refractory Ewing's Sarcoma

Sarcoma

United States, Canada, Australia, Puerto Rico
Universitaire Ziekenhuizen KU Leuven

Unknown

Osteosarcoma and Ewing Sarcoma Treatment Response Assessment With Functional MRI Imaging in Children and Young Adults (FUBEO)

Osteosarcoma | Ewing Sarcoma

Belgium
Providence Health & Services

Completed

α-TEA in Advanced Cancer

Metastatic Sarcoma | Metastatic Carcinoma | Metastatic Lymphoma

United States
Children's Oncology Group
National Cancer Institute (NCI)

Completed

Two Regimens of Combination Chemotherapy in Treating Younger Patients With Newly Diagnosed Localized Ewing Sarcoma Family of Tumors

Ewing Sarcoma of Bone | Localized Ewing Sarcoma/Peripheral Primitive Neuroectodermal Tumor

United States
Yizhuo Zhang

Active, not recruiting

Risk Stratification Oriented Treatment of Pediatric Ewing Sarcoma: a Prospective Multicenter Cohort Study

Ewing Sarcoma | Risk Stratification

China
National University Hospital, Singapore

Unknown

Pilot Study of Expanded , Activated Haploidentical Natural Killer Cell Infusions for Sarcomas (NKEXPSARC)

Ewing Sarcoma | Rhabdomyosarcoma

Singapore
Wuhan Union Hospital, China

Recruiting

Camrelizumab Plus Doxorubicin for the First Line Treatment of Adcanced Soft Tissue Sarcoma

Soft Tissue Sarcoma | Neoplasms, Connective and Soft Tissue | Sarcoma Metastatic | Sarcoma,Soft Tissue

China
National Cancer Institute (NCI)

Terminated

Mithramycin for Children and Adults With Solid Tumors or Ewing Sarcoma

Sarcoma | Ewing Sarcoma

United States
Ann & Robert H Lurie Children's Hospital of Chicago
On Target Laboratories, LLC

Not yet recruiting

Safety and Feasibility of Intraoperative Visualization With Cytalux in Children (Cytalux)

Osteosarcoma | Pediatrics | Metastatic Sarcoma | Pulmonary Metastasis | Fluorescence
Peking University People's Hospital
Peking University Shougang Hospital; Shandong Cancer Hospital and Institute

Recruiting

Weekly Irinotecan Liposomes in Recurrent or Refractory Ewing Sarcoma

Ewing Sarcoma

China
Vanderbilt-Ingram Cancer Center
National Cancer Institute (NCI)

Terminated

Quantitative Imaging Biomarkers of Treatment Response in Osteosarcoma and Ewing Sarcoma

Osteosarcoma | Ewing Sarcoma | Paget's Disease

United States
H. Lee Moffitt Cancer Center and Research Institute
National Pediatric Cancer Foundation

Active, not recruiting

Nab-Paclitaxel and Gemcitabine for Recurrent/Refractory Sarcoma

Soft Tissue Sarcoma | Osteosarcoma | Ewing Sarcoma | Rhabdomyosarcoma

United States
National Cancer Institute (NCI)

Completed

Nivolumab With or Without Ipilimumab in Treating Patients With Metastatic Sarcoma That Cannot Be Removed by Surgery

Stage III Soft Tissue Sarcoma AJCC v7 | Stage IV Soft Tissue Sarcoma AJCC v7 | Pleomorphic Liposarcoma | Metastatic Undifferentiated Pleomorphic Sarcoma | Metastatic Unresectable Sarcoma | Unresectable Soft Tissue Sarcoma | Metastatic Soft Tissue Sarcoma | Locally Advanced Soft Tissue Sarcoma | Metastatic... and other conditions

United States
Centre Antoine Lacassagne

Recruiting

Analysis of the Toxicity and Efficacy of Daily 1 vs 2 Beam Proton Therapy (P1V2)

Osteosarcoma | Ewing Sarcoma | Chondrosarcoma | Chordoma

France
Washington University School of Medicine
Bristol-Myers Squibb; Exelixis

Active, not recruiting

Cabozantinib Combined With PD-1 and CTLA-4 Inhibition in Metastatic Soft Tissue Sarcoma

Metastatic Soft-tissue Sarcoma

United States
Centre Oscar Lambret

Active, not recruiting

Phase II Study of Regorafenib as Maintenance Therapy

Metastatic Soft Tissue Sarcoma

France
Noxopharm Limited

Terminated

A Study of NOX66 Plus Doxorubicin in Anthracycline-naïve, Adult Patients With Soft Tissue Sarcoma

Metastatic Soft-tissue Sarcoma

United States
NanoCarrier Co., Ltd.

Unknown

Dose-Escalation and Expansion Trial of NC-6300 in Patients With Advanced Solid Tumors or Soft Tissue Sarcoma

Sarcoma | Soft Tissue Sarcoma | Solid Tumor | Metastatic Sarcoma

United States
Morphotek

Completed

Sarcoma Study of MORAb-004 Utilization: Research and Clinical Evaluation (SOURCE)

Metastatic Soft Tissue Sarcoma

United States, Australia, France, Italy, Netherlands, Belgium
University of Washington
Aadi Bioscience, Inc.

Active, not recruiting

Nab-Sirolimus and Pazopanib Hydrochloride in Treating Patients With Advanced Nonadipocytic Soft Tissue Sarcomas

Advanced Soft Tissue Sarcoma | Metastatic Soft Tissue Sarcoma | Locally Advanced Soft Tissue Sarcoma

United States
University of Leicester
National Cancer Institute (NCI); Children's Cancer and Leukaemia Group; European... and other collaborators

Unknown

Combination Chemotherapy With or Without Peripheral Stem Cell Transplantation, Radiation Therapy, and/or Surgery in Treating Patients With Ewing's Sarcoma

Sarcoma

United States, Canada, Australia, New Zealand, Puerto Rico
Gustave Roussy, Cancer Campus, Grand Paris

Recruiting

Long Term Brain Toxicity of Chemotherapy in Patients Treated for a Bone TumorDuring Childhood or Adolescence (OSE)

Adults Treated During Childhood or Adolescence for a Malignant Bone Tumor (Osteosarcoma and Ewing Sarcoma)

France
Eli Lilly and Company
Children's Oncology Group

Completed

A Study of Pemetrexed in Children With Recurrent Cancer

Osteosarcoma | Ependymoma | Medulloblastoma | Rhabdomyosarcoma | Sarcoma, Ewing's | Neuroblastoma (Measurable Disease) | Neuroblastoma (Metaiodobenzylguanidine | Positive Evaluable) | Non-brainstem High-grade Glioma

United States
Washington University School of Medicine

Withdrawn

Erlotinib in Combination With Temozolomide in Treating Relapsed/Recurrent/Refractory Pediatric Solid Tumors

Glioma | Osteosarcoma | Ependymoma | Medulloblastoma | Rhabdomyosarcoma | Wilms Tumor | Neuroectodermal Tumor | Ewing's Sarcoma
University of Michigan Rogel Cancer Center
AstraZeneca; Janssen Scientific Affairs, LLC

Active, not recruiting

Trabectedin in Combination With Olaparib in Advanced Unresectable or Metastatic Sarcoma

Sarcoma | Sarcoma Metastatic

United States
Massachusetts General Hospital
Dana-Farber Cancer Institute; PharmaMar

Completed

A Phase II Multi-Strata Study of PM01183 as a Single Agent or in Combination With Conventional Chemotherapy in Metastatic and/or Unresectable Sarcomas

Metastatic Sarcoma

United States
Centre Leon Berard
Novartis; National Cancer Institute, France

Recruiting

HDM201 and Pazopanib in Patients With P53 Wild-type Advanced/Metastatic Soft Tissue Sarcomas (AMPHISARC)

Advanced Soft-tissue Sarcoma | Metastatic Soft-tissue Sarcoma

France
UNICANCER

Recruiting

Comparison of Oral Cyclophosphamide vs Doxorubicin in ≥65 Years Old Advanced or Metastatic Soft Tissue Sarcoma Patients (GERICO14)

Advanced Soft-tissue Sarcoma | Metastatic Soft-tissue Sarcoma

France
University of Colorado, Denver
Agenus Inc.

Recruiting

Doxorubicin Plus Dual Checkpoint Blockade for Soft Tissue Sarcomas

Advanced Soft Tissue Sarcoma | Metastatic Soft Tissue Sarcoma

United States
Istituto Ortopedico Rizzoli

Recruiting

Metformin as Maintenance Therapy in Patients With Bone Sarcoma and High Risk of Relapse (Metform-Bone)

Osteosarcoma | Ewing Sarcoma

Italy
Centre Oscar Lambret
Canceropôle Nord Ouest

Recruiting

Superiority Trial Evaluating Digitalized Information Media for Patients With Advanced Sarcomas Receiving Second Line Treatment. (ePPS-2202)

Sarcoma Metastatic | Locally Advanced Soft Tissue Sarcoma

France
University Medicine Greifswald
Bristol-Myers Squibb; Institut für Klinische Krebsforschung IKF GmbH at Krankenhaus... and other collaborators

Completed

Combined Treatment With Nivolumab and Trabectedin in Patients With Metastatic or Inoperable Soft Tissue Sarcomas (NiTraSarc)

Metastatic Adult Soft Tissue Sarcoma

Germany
Eli Lilly and Company

Recruiting

CAMPFIRE: A Study of Abemaciclib (LY2835219) in Participants With Ewing's Sarcoma

Neoplasm Metastasis | Sarcoma, Ewing

United States, Australia, Spain, Japan, France, Italy, Germany
M.D. Anderson Cancer Center
Lyvgen Biopharma Holdings Limited

Recruiting

Study of LVGN3616 and LVGN6051±LVGN7409 in Combination With Nab-Paclitaxel or Bevacizumab and Cyclophosphamide in Metastatic Solid Tumors

Gastric Cancer | Metastatic Uveal Melanoma | Metastatic Head and Neck Carcinoma | Metastatic Hepatocellular Carcinoma | Metastatic Ovarian Carcinoma | Metastatic Soft Tissue Sarcoma | Metastatic Esophageal | Metastatic HPV Related Solid Tumors

United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Not yet recruiting

Implantable Microdevice for the Delivery of Drugs and Their Effect on Tumors in Patients With Metastatic or Recurrent Sarcoma

Metastatic Sarcoma | Resectable Sarcoma | Recurrent Sarcoma

United States

Clinical Trials on Ewing's Sarcoma Metastatic

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