Clinical Trials on Exercise Associated Pulmonary Arterial Hypertension

Total 2805 results

University of Sheffield
GlaxoSmithKline

Unknown

Repeatability and Sensitivity to Change of Non-invasive Endpoints in PAH (RESPIRE)

Pulmonary Arterial Hypertension
Amsterdam UMC, location VUmc
Vifor Pharma

Unknown

Iron Deficiency In Pulmonary Hypertension

Idiopathic Pulmonary Arterial Hypertension

Netherlands
GB002, Inc.

Recruiting

Efficacy and Safety of Seralutinib in Adult Subjects With PAH (PROSERA)

Pulmonary Arterial Hypertension

United States, Spain, Israel, Korea, Republic of, Netherlands, France, Singapore, United Kingdom, Lithuania, Australia, Latvia, Argentina, Portugal, Greece, Czechia, Puerto Rico, Belgium, Italy, Poland, Romania, Serbia, Austria, Chile, Denma... and more
Bayer

Completed

Comparative PK PD Study in PAH Patients (Fox vs. I-Neb)

Pulmonary Arterial Hypertension

Germany, Austria
Allegheny Singer Research Institute (also known...

Completed

Effect of iNO on Invasively Derived Pulmonary Pressures in Patients With PAH

Pulmonary Arterial Hypertension

United States
National Institutes of Health Clinical Center (CC)

Completed

Endothelial Cell Dysfunction in Pulmonary Hypertension

Secondary Pulmonary Arterial Hypertension

United States
Department of Pulmonary Circulation and Thromboembolic...

Recruiting

LenusPro Pump in PAH Treated With Treprostinil

Pulmonary Arterial Hypertension

Poland
United Therapeutics

Completed

Open-label, Clinical Study to Evaluate the Safety and Tolerability of TreT in Subjects With PAH Currently Using Tyvaso (BREEZE)

Pulmonary Arterial Hypertension

United States
Megan Ballinger

Completed

The Expression and Significance of MiRNA

Pulmonary Arterial Hypertension

United States
United Therapeutics

Completed

Study of Incidence of Respiratory Tract AEs in Patients Treated With Tyvaso® Compared to Other FDA Approved PAH Therapies (Aspire)

Pulmonary Arterial Hypertension

United States
Geno LLC

Withdrawn

Study to Assess Acute Vasodilation Response of Inhaled Nitric Oxide (EAGLE)

Pulmonary Arterial Hypertension

United States
VentriPoint Diagnostics Ltd.

Completed

Assessmet of Patients With PAH Right Ventricular Volume

Pulmonary Arterial Hypertension

United States, Canada
Chinese Pulmonary Vascular Disease Research Group

Recruiting

Efficacy and Safety Evaluation of Tolvaptan in the Treatment of Patients With RHF Caused by PAH

Pulmonary Arterial Hypertension | Randomized Controlled Trial

China
Bial - Portela C S.A.

Terminated

Effect of Age-gender on the Pharmacokinetic and Pharmacodynamic Profiles of BIA 5 1058

Pulmonary Arterial Hypertension
Bial - Portela C S.A.

Completed

Absorption, Distribution, Metabolism and Excretion of BIA 5-1058 (ADME)

Pulmonary Arterial Hypertension

Netherlands
Pfizer's Upjohn has merged with Mylan to form Viatris...

No longer available

An Open Label Access Study For Subjects Who Completed A1481156

Pulmonary Arterial Hypertension

India
Hanmi Pharmaceutical Company Limited

Completed

To Compare the Pharmacokinetics of Traclear 62.5 mg Tablets and HGP1206 125mg 1 Tablet in Healthy Male Volunteers

Pulmonary Arterial Hypertension

Korea, Republic of
Karos Pharmaceuticals

Completed

Single and Multiple Ascending Doses Clinical Pharmacology Study With KAR5585

Pulmonary Arterial Hypertension

United States
United Therapeutics

Completed

Tyvaso Dosing and Titration Evaluation: TyTRATE Registry

Pulmonary Arterial Hypertension

United States, Puerto Rico
United Therapeutics

Completed

Comparative Bioavailability of Treprostinil Diethanolamine Manufactured by Two Independent Facilities

Pulmonary Arterial Hypertension

United States
United Therapeutics

Completed

Pharmacokinetic Linearity and Comparative Bioavailability of Treprostinil Diethanolamine

Pulmonary Arterial Hypertension

United States
University of Zurich

Completed

Maximal Exercise Capacity at 2500 m of High Altitude

High Altitude Pulmonary Hypertension | Maximal Exercise Capacity

Switzerland
Bayer

Completed

Post-Marketing Surveillance of Ventavis® in Chinese Patients With Primary Pulmonary Hypertension (PPH)

Primary Hypertension

China
Assistance Publique - Hôpitaux de Paris

Withdrawn

Evaluation of the Pulmonary Vascular Reactivity Test in Patients With Pulmonary Arterial Hypertension and a Cardiac Shunt (ReVAch)

Pulmonary Arterial Hypertension With Congenital Cardiac Shunt
University of Campania "Luigi Vanvitelli"

Completed

DNA Methylation Dynamics Underlying Arterial Remodeling in PAH Patients: CLEOPAHTRA Clinical Trial (CLEOPAHTRA)

Pulmonary Arterial Hypertension | Pulmonary Arterial Remodeling

Italy
Medical University of Graz

Enrolling by invitation

Non-contrast Enhanced Cardiac Magnetic Resonance Imaging in the Diagnosis and Classification of Pulmonary Hypertension (CMR-PH)

Pulmonary Hypertension | Elevated Mean Pulmonary Arterial Pressure | Normal Mean Pulmonary Arterial Pressure

Austria
Bial - Portela C S.A.

Completed

Effect of Food on BIA 5-1058

Pulmonary Arterial Hypertension
Bial - Portela C S.A.

Completed

Effect of BIA 5-1058 400 mg on the Steady State Pharmacokinetics of Bosentan

Pulmonary Arterial Hypertension

Germany
Lung Biotechnology PBC

Completed

A Multi-Center, Open-Label, Multiple Dose, Dose Finding Study Exploring the Safety and Tolerability of Beraprost Sodium Modified Release in PAH Patients

Pulmonary Arterial Hypertension

United States, Ireland, Belgium
Merck Sharp & Dohme LLC

Completed

A Rising Single Dose Study of the Safety, Tolerability, Pharmacokinetics (PK) and Pharmacodynamics of MK-8892 (MK-8892-001)

Pulmonary Arterial Hypertension
Vanderbilt University

Completed

Dysregulation of Lipid Metabolism and Right Ventricular Function in PAH

Pulmonary Arterial Hypertension

United States
Prof David S Celermajer

Completed

Bosentan and Pulmonary Endothelial Function (PARBO)

Pulmonary Arterial Hypertension
Pfizer

Terminated

A Pharmacokinetic Drug-Drug Interaction (DDI) Study Between Sitaxsentan And Sildenafil, And Between Sitaxsentan And Tadalafil After Multiple Doses

Pulmonary Arterial Hypertension

Singapore
Pfizer

Terminated

A Non-Interventional, Patient Registry For The Collection Of Pre-Defined Safety Data In Patients Prescribed Thelin (PROSE)

Pulmonary Arterial Hypertension

Belgium, Germany, France
United Therapeutics

Completed

A Bioavailability Study Comparing Treprostinil Diethanolamine Oral Tablets and Oral Solution in Healthy Volunteers

Pulmonary Arterial Hypertension

United States
GB002, Inc.

Not yet recruiting

Open-label Extension Study of Seralutinib in Adult Subjects With PAH (PROSERA-EXT)

Pulmonary Arterial Hypertension

United States
Bellerophon Pulse Technologies
Worldwide Clinical Trials

Withdrawn

Study of PAH Subjects With LTOT Use That Have Demonstrated Improved Exercise Tolerance With the Use of Inhaled Nitric

Pulmonary Arterial Hypertension

United States, Canada
Lung Biotechnology PBC

Completed

Beraprost-314d Added-on to Tyvaso® (BEAT) (BEAT)

Pulmonary Arterial Hypertension

United States, Israel
United Therapeutics

Withdrawn

Safety and Efficacy of Inhaled Treprostinil in Patients With PAH (INTREPID)

Pulmonary Arterial Hypertension
United Therapeutics

Withdrawn

Inhaled Treprostinil for PAH: Open-label Extension (INTREPID - OL)

Pulmonary Arterial Hypertension
University of Zurich

Completed

Retrospective Data Analysis of Data From the Zurich PH Registry

Pulmonary Hypertension | Pulmonary Artery Hypertension | Chronic Thromboembolic Pulmonary Hypertension

Switzerland
The Third Xiangya Hospital of Central South University
Xiangya Hospital of Central South University

Unknown

Testing of HIV Protease Inhibitors to Suppress Inflammation and Improve Cardio Pulmonary Hemodynamics in Subjects With Pulmonary Arterial Hypertension

Pulmonary Arterial Hypertension

China
Johns Hopkins University
National Heart, Lung, and Blood Institute (NHLBI); National Center for Advancing...

Recruiting

Mono vs. Dual Therapy for Pediatric Pulmonary Arterial Hypertension (MoD)

Pediatric Pulmonary Hypertension

United States, Canada
Gazi University

Active, not recruiting

Evaluation of the Strength of Handgrip in Patients With Pulmonary Artery Hypertension

Pulmonary Hypertension

Turkey
Mads Ersbøll

Recruiting

Dapagliflozin in Pulmonary Arterial Hypertension (DAPAH)

Pulmonary Arterial Hypertension | Chronic Thromboembolic Pulmonary Hypertension

Denmark
Actelion

Completed

A Clinical Study to Investigate the Long-term Safety of the Drug Macitentan in Patients With Pulmonary Hypertension Who Were Previously Treated With Macitentan in Clinical Studies. (UMBRELLA)

Pulmonary Arterial Hypertension | Chronic Thromboembolic Pulmonary Hypertension

Belgium, France, Poland, Russian Federation, Belarus, Turkey, Ukraine
Viatris Pharmaceuticals Japan Inc

Completed

Revatio Special Investigation for Long-term Use in Pediatric Patients

Pulmonary Arterial Hypertension

Japan
Actelion

Completed

A Registry for Patients Taking Uptravi (SPHERE)

Pulmonary Arterial Hypertension

United States, Puerto Rico
Gmax Biopharm Australia Pty Ltd.
Metaclinical; Syneos Heath

Completed

A Study to Investigate Safe and Tolerable Dose of GMA301 Injection in Healthy Volunteers

Pulmonary Arterial Hypertension

Australia
Bial - Portela C S.A.

Completed

Effect of BIA 5-1058 400 mg on the Steady State Pharmacokinetics of Sildenafil

Pulmonary Arterial Hypertension

Germany

Clinical Trials on Exercise Associated Pulmonary Arterial Hypertension

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