Clinical Trials on Exocrine Pancreatic Insufficiency: Cystic Fibrosis in Portugal

Total 44 results

Centro Hospitalar e Universitário de Coimbra, E...
University of Coimbra

Recruiting

Exocrine Pancreatic Insufficiency After Acute Pancreatitis and Pancreatic Enzyme Replacement Therapy

Immunology | Acute Pancreatitis | Exocrine Pancreatic Insufficiency | Gut Microbiota

Portugal
Pilar Azevedo
Queen's University, Belfast; Medical University Innsbruck; Cystic Fibrosis Foundation and other collaborators

Recruiting

COVID-19 Antibody Responses In Cystic Fibrosis (CAR-CF)

COVID-19 | Cystic Fibrosis

Portugal
Universitaire Ziekenhuizen KU Leuven
KU Leuven; Vertex Pharmaceuticals Incorporated; University of Lisbon

Withdrawn

Organoid Study R334W

Cystic Fibrosis

Spain, Italy, France, Belgium, Portugal
Centro Hospitalar De São João, E.P.E.

Unknown

Impact of Suction in the EUS-guided Fine Needle Biopsy of Solid Pancreatic Lesions

Pancreatic Neoplasm | Biopsy, Fine-Needle | Endosonography

Portugal
Vertex Pharmaceuticals Incorporated

Completed

A Study to Evaluate the Safety and Efficacy of VX-121 Combination Therapy in Subjects With Cystic Fibrosis

Cystic Fibrosis

United States, Netherlands, United Kingdom, Germany, Portugal
Spyryx Biosciences, Inc.

Completed

An Efficacy and Safety Study of SPX-101 Inhalation Solution in Subjects With Cystic Fibrosis ((HOPE-1))

Cystic Fibrosis

United Kingdom, Canada, France, Italy, Portugal
Bambino Gesù Hospital and Research Institute
Radboud University Medical Center; University of Exeter; Consorzio per Valutazioni...

Recruiting

A New Posaconazole Dosing Regimen for Paediatric Patients With Cystic Fibrosis and Aspergillus Infection (cASPerCF)

Cystic Fibrosis | Aspergillosis

Ireland, Spain, Netherlands, France, United Kingdom, Czechia, Germany, Greece, Italy, Portugal, Switzerland
Vertex Pharmaceuticals Incorporated

Active, not recruiting

Study to Evaluate Elexacaftor/Tezacaftor/Ivacaftor (ELX/TEZ/IVA) Long-term Safety and Efficacy in Subjects Without F508del

Cystic Fibrosis

Spain, Belgium, Netherlands, France, Canada, Germany, Sweden, Switzerland, Italy, Czechia, Portugal, Austria, Hungary, Norway, Poland
Vertex Pharmaceuticals Incorporated

Completed

Evaluation of Efficacy and Safety of Elexacaftor/Tezacaftor/Ivacaftor (ELX/TEZ/IVA) in Cystic Fibrosis Subjects Without an F508del Mutation

Cystic Fibrosis

Spain, Belgium, Netherlands, France, Canada, Germany, Sweden, Italy, Czechia, Switzerland, Portugal, Austria, Hungary, Norway, Poland
Boehringer Ingelheim

Completed

Tiotropium Bromide in Cystic Fibrosis

Cystic Fibrosis

United States, Australia, Austria, Belgium, Canada, Czech Republic, France, Germany, Hungary, Ireland, Israel, Italy, Poland, Portugal, Russian Federation, Slovakia, South Africa, Spain, Switzerland, United Kingdom
Vertex Pharmaceuticals Incorporated

Completed

A Phase 3 Study of VX-121 Combination Therapy in Participants With Cystic Fibrosis (CF) Heterozygous for F508del and a Minimal Function Mutation (F/MF)

Cystic Fibrosis

United States, Spain, United Kingdom, New Zealand, Israel, Australia, Ireland, Germany, Sweden, Czechia, Portugal, Hungary
Boehringer Ingelheim

Completed

Safety and Efficacy of 12-wk Treatment With Two Doses of Tiotropium Respimat in Cystic Fibrosis

Cystic Fibrosis

United States, Australia, Belgium, France, Germany, Italy, Netherlands, New Zealand, Portugal, Russian Federation, United Kingdom
Corbus Pharmaceuticals Inc.
Cystic Fibrosis Foundation

Completed

Trial to Evaluate Efficacy and Safety of Lenabasum in Cystic Fibrosis

Cystic Fibrosis

United States, United Kingdom, Sweden, Canada, France, Austria, Germany, Netherlands, Italy, Belgium, Portugal, Bulgaria, Czechia, Greece, Hungary, Poland, Romania, Russian Federation, Serbia, Slovakia, Spain
Vertex Pharmaceuticals Incorporated

Active, not recruiting

A Study Evaluating the Long-term Safety and Efficacy of VX-121 Combination Therapy

Cystic Fibrosis

United States, Spain, United Kingdom, Belgium, Netherlands, Denmark, Israel, New Zealand, France, Australia, Ireland, Germany, Sweden, Canada, Czechia, Switzerland, Portugal, Italy, Austria, Hungary, Norway, Poland, Greece
Gilead Sciences
Covance; ClinPhone, Inc.; Chiltern International Inc.

Completed

Aztreonam for Inhalation Solution vs Tobramycin Inhalation Solution in Patients With Cystic Fibrosis & Pseudomonas Aeruginosa

Cystic Fibrosis

Belgium, France, Germany, Italy, Netherlands, Spain, United States, Ireland, United Kingdom, Portugal, Austria, Denmark, Switzerland
Zambon SpA

Completed

Efficacy and Safety of Inhaled CMS in Bronchiectasis Subjects With Chronic P. Aeruginosa Infection. (PROMIS-I) (PROMIS-I)

Non Cystic Fibrosis Bronchiectasis

Australia, Greece, Israel, Italy, Portugal, Belgium, Germany, Netherlands, New Zealand, Spain, Switzerland, United Kingdom
Zambon SpA

Terminated

Trial in Non-cystic Fibrosis Bronchiectasis Patients With Chronic Lung Infections Treated With Colistimethate Sodium. (PROMIS-II)

Non Cystic Fibrosis Bronchiectasis

United States, Argentina, Australia, Canada, France, Germany, Greece, Israel, Italy, New Zealand, Poland, Portugal
Insmed Incorporated

Active, not recruiting

A Study to Assess the Efficacy, Safety, and Tolerability of Brensocatib in Participants With Non-Cystic Fibrosis Bronchiectasis (ASPEN)

Non-Cystic Fibrosis Bronchiectasis

New Zealand, United States, Argentina, Australia, Austria, Belgium, Brazil, Bulgaria, Canada, Chile, Colombia, Denmark, France, Germany, Greece, Hungary, Ireland, Israel, Italy, Japan, Korea, Republic of, Latvia, Malaysia, Mexico, Nethe... and more
European Organisation for Research and Treatment...

Completed

Fluorouracil With or Without Cisplatin in Treating Patients With Advanced or Metastatic Cancer of the Pancreas

Pancreatic Cancer

France, Belgium, Israel, Italy, Portugal
Dr. Yaacov Lawrence

Completed

Celiac Plexus Radio-Surgery for Pain Management

Pain | Advanced Cancer | Pancreas Cancer

United States, Israel, Portugal, Canada
Ipsen

Terminated

Lanreotide 120mg Effectiveness in Subjects With Pancreatic Neuroendocrine Tumours (PanNET) in Routine Clinical Practice. (PanNET)

Pancreatic Neuroendocrine Tumor

Spain, Portugal
Incyte Corporation

Terminated

A Study of Ruxolitinib in Pancreatic Cancer Patients

Pancreatic Cancer

United States, France, Colombia, Israel, Portugal, Netherlands, Chile, Puerto Rico, Sweden, Austria, Denmark, Mexico, Ireland, Switzerland
Ipsen

Completed

Quality-Of-Life QLQ-GINET21 Questionnaire In The Treatment Of Patients With Gastrointestinal Neuroendocrine Tumours (QUALINETS)

Gastrointestinal Neuroendocrine Tumours

Spain, Portugal
Celgene

Completed

Nab-paclitaxel and Gemcitabine vs Gemcitabine Alone as Adjuvant Therapy for Patients With Resected Pancreatic Cancer (the "Apact" Study) (apact)

Digestive System Diseases | Neoplasms | Neoplasms by Site | Endocrine System Diseases | Digestive System Neoplasms | Endocrine Gland Neoplasms | Pancreatic Neoplasms | Pancreatic Diseases | Gemcitabine | Antimetabolites, Antineoplastic

United States, Korea, Republic of, Canada, France, Spain, Belgium, Austria, Czechia, Denmark, Italy, Hong Kong, Singapore, Taiwan, Germany, Hungary, Australia, United Kingdom, Portugal, Ireland, Finland, Netherlands
Sumitomo Pharma America, Inc.

Completed

A Study of Napabucasin Plus Nab-Paclitaxel With Gemcitabine in Adult Patients With Metastatic Pancreatic Adenocarcinoma (CanStem111P)

Carcinoma, Pancreatic Ductal

United States, France, Netherlands, Spain, Taiwan, China, Belgium, Korea, Republic of, Austria, Singapore, Japan, Italy, Germany, Portugal, Poland, Czechia, Australia, Canada, Russian Federation, Ukraine
Jonel Trebicka

Completed

Predicting Acute-on-Chronic Liver Failure in Cirrhosis (PREDICT) Study (PREDICT)

Liver Cirrhosis With Acute Decompensation

Spain, Germany, Denmark, Austria, Belgium, United Kingdom, Netherlands, Switzerland, Hungary, Italy, France, Portugal, Slovakia, Turkey
NantCell, Inc.
Takeda

Terminated

QUILT-2.014: Gemcitabine and AMG 479 in Metastatic Adenocarcinoma of the Pancreas (GAMMA)

Cancer | Pancreatic Cancer | Advanced Solid Tumors | Metastatic Cancer | Bone Metastases | Solid Tumors | Pancreas Cancer | Adenocarcinoma of the Pancreas | Oncology | Cancer of Pancreas | Metastatic Pancreatic Cancer | Metastases | Cancer of the Pancreas | Advanced Malignancy | Oncology Patients | Endocrine Cancer

Italy, Spain, United Kingdom, Belgium, Canada, Denmark, Romania, United States, Germany, Netherlands, Korea, Republic of, Russian Federation, Australia, Austria, Lithuania, Portugal, Greece, Poland, Switzerland, Serbia, Bulgaria, ... and more
Eli Lilly and Company

Completed

A Phase 3 Trial of ALIMTA (LY231514, Pemetrexed) Plus GEMZAR Versus GEMZAR in Patients With Unresectable or Metastatic Cancer of the Pancreas.

Pancreatic Neoplasms | Metastases, Neoplasm

United States, France, United Kingdom, Germany, Taiwan, Spain, Belgium, Portugal, Peru, Austria, Italy, Sweden, Netherlands, Venezuela, Argentina, Australia, Colombia, Greece
European Foundation for Study of Chronic Liver...

Recruiting

Liver Transplantation in Patients With CirrHosis and Severe Acute-on-Chronic Liver Failure: iNdications and outComEs (CHANCE)

Liver Diseases | Liver Cirrhosis | Acute-On-Chronic Liver Failure | Liver Transplant; Complications

Spain, United States, Germany, Belgium, United Kingdom, Japan, Mexico, Taiwan, Korea, Republic of, Canada, France, Australia, Italy, Argentina, Austria, Brazil, Colombia, Czechia, Hong Kong, India, Netherlands, New Zealand, Poland, Po... and more
Abbott

Completed

The Effect of Paricalcitol Capsules on Reducing Albuminuria in Patients With Type 2 Diabetic Nephropathy Being Treated With Renin-angiotensin System Inhibitors (VITAL)

Diabetic Nephropathy | Chronic Kidney Disease

United States, Germany, Greece, Italy, Netherlands, Poland, Portugal, Puerto Rico, Spain, Taiwan
Amgen

Completed

Bone Biopsy Study For Dialysis Patients With Secondary Hyperparathyroidism of End Stage Renal Disease (BONAFIDE)

Secondary Hyperparathyroidism

United States, Italy, Belgium, Switzerland, Hungary, Spain, Turkey, Poland, Portugal, United Kingdom, Czech Republic, Macedonia, The Former Yugoslav Republic of
Abbott

Completed

Evaluation of the Effectiveness of Paricalcitol Versus Cinacalcet With Low-Dose Vitamin D (IMPACT SHPT)

Hemodialysis | Chronic Kidney Disease | Secondary Hyperparathyroidism

United States, Czech Republic, Denmark, Germany, Greece, Italy, Netherlands, Portugal, Russian Federation, Spain, Sweden, United Kingdom
Amgen

Terminated

Efficacy and Safety of Cinacalcet in Pediatric Patients With Secondary Hyperparathyroidism (SHPT) and Chronic Kidney Disease (CKD) on Dialysis

Chronic Kidney Disease, Secondary Hyperparathyroidism

United States, Belgium, Italy, Hungary, Czechia, France, Germany, Greece, Spain, Poland, Russian Federation, Ukraine, New Zealand, Slovakia, Lithuania, Portugal
Amgen

Completed

Extension Study of Etelcalcetide for Treatment of Secondary Hyperparathyroidism in Patients With Chronic Kidney Disease on Hemodialysis

Hyperparathyroidism, Secondary

United States, Belgium, Italy, Switzerland, Canada, Turkey, Spain, Australia, Austria, Israel, Czechia, Hungary, Poland, France, Russian Federation, Germany, Denmark, Greece, Latvia, Lithuania, Netherlands, New Zealand, Portugal, Sweden
Amgen

Completed

Head-to-Head Study of Etelcalcetide (AMG 416) and Cinacalcet

Chronic Kidney Disease | Secondary Hyperparathyroidism

United States, Italy, Belgium, Denmark, Switzerland, Canada, Turkey, Spain, Austria, Germany, Hungary, Greece, France, Poland, Russian Federation, Czechia, Latvia, Lithuania, New Zealand, Portugal, Sweden, Estonia
Pathalys Pharma
Launch Therapeutics

Recruiting

Parathyroid Hormone (PTH) Attenuation Trial in Hemodialysis-2 (PATH-2)

Secondary Hyperparathyroidism | End Stage Kidney Disease

United States, Bulgaria, Portugal, Spain, Serbia, Poland
Pathalys Pharma
Launch Therapeutics

Recruiting

Parathyroid Hormone (PTH) Attenuation Trial in Hemodialysis-1 (PATH-1)

Secondary Hyperparathyroidism | End-stage Kidney Disease (ESKD)

United States, Bulgaria, Spain, Portugal, Poland, Serbia
Boehringer Ingelheim
Eli Lilly and Company

Completed

Efficacy and Safety of Empagliflozin (BI 10773) in Patients With Type 2 Diabetes and Renal Impairment

Diabetes Mellitus, Type 2 | Renal Insufficiency

United States, Canada, France, Hong Kong, India, Malaysia, Netherlands, Philippines, Poland, Portugal, Russian Federation, Slovakia, South Africa, Spain, United Kingdom
CytoSorbents, Inc

Recruiting

CytOSorb TreatMent Of Critically Ill PatientS Registry (COSMOS)

Sepsis | Burns | Septic Shock | Trauma | Infectious Disease | Pancreatitis | Acute Respiratory Distress Syndrome | Liver Transplant; Complications | Drug Overdose | Acute Liver Failure | Cardiogenic Shock | Rhabdomyolysis | Acute on Chronic Liver Failure | Hemophagocytic Lymphohistiocytoses | Extracorporeal Life Support and other conditions

Spain, Italy, Germany, Portugal
Bayer

Completed

Phase IIb Safety and Efficacy Study of Different Oral Doses of BAY94-8862 in Subjects With Worsening Chronic Heart Failure and Left Ventricular Systolic Dysfunction and Either Type 2 Diabetes Mellitus With or Without Chronic Kidney Disease or Chronic Kidney Disease Alone (ARTS-HF)

Heart Failure

France, Taiwan, United States, Turkey, Spain, Greece, Portugal, Germany, Canada, Austria, Czechia, Denmark, Israel, Korea, Republic of, Poland, South Africa, Sweden, Bulgaria, Italy, Finland, Hungary, Lithuania, Netherlands, Australia, ...
Bayer

Completed

An add-on Study to the FIGARO-DKD Study Called FIGARO-BM to Learn About the Link Between Biomarkers (Substances in the Blood Used as Indicators of Biological Processes, Disease Processes or Responses to Medication) and Finerenone in FIGARO-DKD Participants (FIGARO-BM)

Type 2 Diabetes Mellitus | Chronic Kidney Disease

Spain, Belgium, United States, Russian Federation, Hong Kong, Singapore, Taiwan, Korea, Republic of, Canada, Austria, Italy, Japan, Denmark, Australia, Bulgaria, Czechia, Finland, Israel, Netherlands, Sweden, Portugal
Lexicon Pharmaceuticals
Sanofi

Terminated

Effect of Sotagliflozin on Cardiovascular and Renal Events in Participants With Type 2 Diabetes and Moderate Renal Impairment Who Are at Cardiovascular Risk (SCORED)

Heart Failure | Chronic Kidney Diseases | Type 2 Diabetes Mellitus

Estonia, Belgium, Sweden, Italy, China, United States, Canada, Bulgaria, Chile, Denmark, Hungary, Latvia, Mexico, Russian Federation, Serbia, Spain, Portugal, Romania, Turkey, Poland, Lithuania, Argentina, Australia, Brazil, Czechia, France, Georg... and more
Actuate Therapeutics Inc.

Active, not recruiting

9-ING-41 in Patients With Advanced Cancers

Sarcoma | Cancer | Breast Neoplasms | Neoplasm Metastasis | Pancreatic Neoplasms | Pancreatic Cancer | Pancreatic Adenocarcinoma | Bone Cancer | Malignant Glioma | Bone Metastases | Pancreas Cancer | Renal Cancer | Refractory Non-Hodgkin Lymphoma | Bone Neoplasm | Neoplasm, Breast | Refractory Cancer | Refractory Neoplasm | Resistant... and other conditions

United States, Belgium, Canada, Spain, France, Netherlands, Portugal
Bayer

Completed

Efficacy and Safety of Finerenone in Subjects With Type 2 Diabetes Mellitus and Diabetic Kidney Disease (FIDELIO-DKD)

Chronic Kidney Disease

Belgium, Finland, France, China, Hong Kong, Switzerland, United States, Turkey, Greece, New Zealand, Poland, South Africa, Spain, Korea, Republic of, Portugal, Taiwan, Japan, Russian Federation, Singapore, Australia, Netherlands, ... and more

Clinical Trials on Exocrine Pancreatic Insufficiency: Cystic Fibrosis in Portugal

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