Clinical Trials on Extensively Drug Resistant Tuberculosis

Total 461 results

University of Southern California
National Institute of Mental Health (NIMH); University of California, San Francisco

Recruiting

Model-based Electrical Brain Stimulation

Medication Refractory Epilepsy Patients With Electrodes Already Implanted Based on Clinical Criteria for Standard Monitoring

United States
University of Southern California
Vitaflo International, Ltd

Terminated

Betaquik as an Adjunct to Dietary Management of Epilepsy in Adults on the Modified Atkins Diet

Epilepsy | Seizures | Ketosis | Seizure Disorder | Ketogenic Dieting | Epilepsy Intractable

United States
University Heart Center Freiburg - Bad Krozingen

Unknown

Effect of Clopidogrel Loading and Risk of PCI (EXCELSIOR)

Coronary Artery Disease | Drug Resistance

Germany
University Heart Center Freiburg - Bad Krozingen

Completed

Efficacy of Adjusted Clopidogrel Dose in Patients With Insufficient Platelet Inhibition

Coronary Artery Disease | Drug Resistance

Germany
Johns Hopkins University
National Institute of Allergy and Infectious Diseases (NIAID); National Institutes... and other collaborators

Active, not recruiting

A Nurse Case Management Intervention to Improve MDR-TB/HIV Co-Infection Outcomes

HIV | MDR-TB

South Africa
Department of Medical Research, Lower Myanmar
Kangwon National University

Completed

Molecular Assessment of Drug Resistance Markers in Asymptomatic Malaria Cases and Malaria Antibody Kinetic

Malaria | Increased Drug Resistance | Asymptomatic Infection
Michael A. Gelfand, MD, PhD
Epilepsy Foundation

Completed

Novel Helmet Design in Patients With Seizures

Generalized Tonic Clonic Seizure | Drug Resistant Epilepsy | Drop Seizures | Complex Partial Seizure | Fall Due to Seizure

United States
Epicentre
Medecins Sans Frontieres, Netherlands; Minisitry of Public Health, Niger

Completed

Prevention of Nosocomial Infections (CleanKids) (CleanKids)

Severe Acute Malnutrition | Health Care Associated Infection | Multi Drug Resistant Organisms
NeuroPro Therapeutics, Inc.

Completed

Safety and Pharmacokinetic Study of NPT 2042 Soft-gelatin Capsules Administered Orally to Healthy Adult Subjects

Epilepsy | Alzheimer Disease | Epilepsy Intractable

United States
Hospital Universitari de Bellvitge
Hospital Clinic of Barcelona; Carlos III Health Institute; Public Health Agency...

Recruiting

The Impact of Air Pollution on the Consumption of Antimicrobials in the General Population (ONAIR)

Air Pollution | Community-acquired Pneumonia | Drug Resistance, Microbial

Spain
Thomas Jefferson University
Medtronic

Completed

Cardiac Rhythm Abnormalities in Patients With Refractory Epilepsy at High Risk for Sudden Death

Arrhythmia | Refractory Epilepsy | Sudden Death

United States
Glasgow Caledonian University
NHS Lothian; University of Strathclyde; NHS Lanarkshire; Nick Graves Independent...

Completed

Evaluation of Cost of Nosocomial Infection (ECONI)

Drug Resistance, Microbial | Crossing Infections

United Kingdom
Myat Htut Nyunt
Kangwon National University

Completed

Molecular Assessment of Artemisinin Resistance Markers in Eastern and Western Border Areas of Myanmar

Day-3 Positive of Parasitaemia | Prevalence of Drug Resistance Gene Mutation

Myanmar
Region Örebro County
University Hospital, Linkoeping

Completed

Local Collagen-Gentamicin and Extra Fixation of the Sternum for Prevention of Sternal Wound Infection in Cardiac Surgery (LOGIX)

Postoperative Wound Infection | Drug Resistance, Bacterial

Sweden
Hospital Italiano de Buenos Aires
International Club of Ascites

Active, not recruiting

Prediction of Multidrug-resistant Bacterial Infection in Patients With Cirrhosis

Liver Cirrhosis | Bacterial Infections | Drug Resistance, Multiple

Argentina
Nanjing First Hospital, Nanjing Medical University

Completed

Helicobacter Pylori 23S rRNA/gyrA Gene Mutation Detection Kit (Fluorescence PCR Fusion Curve Method)

Helicobacter Pylori Infection | Helicobacter Pylori gyrA Levofloxacin Resistance Mutation | Fecal Drug Resistance Gene Detection | Helicobacter Pylori Infection, Susceptibility to

China
Neuroelectrics Corporation

Recruiting

Pivotal-Safety and Therapeutic Measures of tDCS in Patients With Refractory Focal Epilepsy

Epilepsy | Seizures | Refractory Epilepsy | Epilepsy, Tonic-Clonic | Epilepsy in Children | Seizures, Focal | Focal Seizure

Spain, United States, France, Belgium
UMC Utrecht
ZonMw: The Netherlands Organisation for Health Research and Development

Completed

Burden of Antibiotic Resistance in Gram-Negative Infections in Dutch Hospitals (GRAND-ABC)

Infection Resistant to Drugs | Gram-Negative Bacterial Infection

Netherlands
Walter K. Kraft
Merck Sharp & Dohme LLC

Completed

Doravirine, Rifapentine and Isoniazid Interaction (DORIIS)

Latent Tuberculosis | Human Immunodeficiency Virus | Drug Interaction Potentiation | Rifamycins Causing Adverse Effects in Therapeutic Use

United States
Genelex Corporation

Completed

Drug & Gene Interaction Risk Analysis With & Without Genetic Testing Among Patients Undergoing MTM

Drug Metabolism, Poor, CYP2D6-RELATED | Drug Metabolism, Poor, CYP2C19-RELATED | Cytochrome P450 CYP2D6 Enzyme Deficiency | Cytochrome P450 CYP2C9 Enzyme Deficiency | Cytochrome P450 CYP2C19 Enzyme Deficiency | Poor Metabolizer Due to Cytochrome P450 CYP2D6 Variant | CYP2D6 Polymorphism | Ultrarapid... and other conditions

United States
Hat Yai Medical Education Center

Terminated

Aerosolized Plus Intravenous vs. Intravenous Colistin for VAP Due to Pandrugs-resistant A. Baumannii in Neonates

Pneumonia, Ventilator-Associated | Colistin Adverse Reaction | Infection Due to Multidrug Resistant Acinetobacter | Infection Resistant to Multiple Drugs

Thailand
Duke University
National Institute of Allergy and Infectious Diseases (NIAID)

Completed

Multi-Drug Resistant Organism Network (MDRO Network)

Bacterial Infections | Infections Resistant to Multiple Drugs

China, United States, Australia, Colombia
Danone Nutricia SpA Società Benefit

Recruiting

Effectiveness and Impact on the Quality of Life of Ketogenic Diet in Pediatric Patients

Autism Spectrum Disorder | Drug Resistant Epilepsy | Chronic Migraine | Brain Tumor, Pediatric

Italy
University of Sao Paulo

Unknown

Impact of Ketogenic Diet on Lipoproteins in Refractory Epilepsy (Ketonutri)

Epilepsy | Quality of Life | Cardiovascular Disease | Non-alcoholic Fatty Liver Disease

Brazil
Peking University Third Hospital
Beijing Friendship Hospital; Beijing Chao Yang Hospital

Enrolling by invitation

Epidemiological Investigation of Sepsis in Obstetrics Admitted to ICU

Intensive Care Units | Drug Resistance, Multiple | Maternal Sepsis

China
National Health Research Institutes, Taiwan
Kaohsiung Medical University Chung-Ho Memorial Hospital; Taipei Veterans General... and other collaborators

Unknown

The Emergence of RAS Mutations in Metastatic Colorectal Cancer Patients Receiving Cetuximab Treatment

Colorectal Cancer | Drug Resistance | Mass Spectrometry | RAS-RAF Pathway Deregulation

Taiwan
CENTOGENE GmbH Rostock

Withdrawn

Biomarker for Creatine Deficiency Syndromes (BioCDS) (BioCDS)

Intellectual Disability | Developmental Delay | Intractable Epilepsy | Movement Disorder | Behavioral Disorder

India, Sri Lanka, Egypt
Peking University People's Hospital
Peking University; Northwestern University

Unknown

Epigenetic Biomarker for Advanced Osteosarcoma Using Famitinib and Camrelizumab (EBAOFC)

Drug Resistance to Famitinib and Camrelizumab | Biomarkers for Efficacy and Toxicity

China
Mayo Clinic
National Cancer Institute (NCI)

Recruiting

Durvalumab and Lurbinectedin for the Treatment of Relapsed or Refractory Small Cell Lung Cancer

Platinum-Resistant Lung Small Cell Carcinoma | Platinum-Sensitive Lung Small Cell Carcinoma | Recurrent Extensive Stage Lung Small Cell Carcinoma | Refractory Extensive Stage Lung Small Cell Carcinoma

United States
Maimonides Medical Center

Completed

Oral Aspirin + Ketamine as Adjunct to Oral Antidepressant Therapy for Depression

Analgesia | Depressive Symptoms | Major Depressive Disorder | Treatment Resistant Depression | Ketamine | Physiological Effects of Drugs | Analgesics, Non-Narcotic | Peripheral Nervous System Agents | Central Nervous System Depressants | Neurotransmitter Agents | Sensory System Agents | Anti-Inflammatory Agents and other conditions

United States
IRCCS Eugenio Medea

Recruiting

Structural-functional Connectome in Drug-resistant Epilepsies and Neurodevelopmental Syndromes With Epilepsy

Epilepsy | Angelman Syndrome | Dup15q Syndrome

Italy
University Hospital, Strasbourg, France

Unknown

Study of Predictive Biomarkers for Rational Management of Drug-resistant Epilepsy Associated With Focal Cortical Dysplasia (SPREAD)

Focal Epilepsy | Refractory Epilepsy | Focal Cortical Dysplasia

France
The University of Queensland
University of California, Los Angeles; Monash University; University of Sydney; Griffith University and other collaborators

Active, not recruiting

Gonorrhoea Resistance Assessment by Nucleic Acid Detection (GRANDII) (GRANDII)

Gonorrhea | Antimicrobial Stewardship | Drug Resistance, Microbial

Australia
Northwell Health
Medtronic

Terminated

Long-term Cardiac Monitoring in Epilepsy (LOOP)

Generalized Epilepsy | Intractable Epilepsy | Focal Epilepsy | Epileptic Encephalopathy | Lennox Gastaut Syndrome | Symptomatic Epilepsy

United States
PENTA Foundation
ViiV Healthcare; Hospital Universitario 12 de Octubre; Cromsource; PHPT Foundation

Recruiting

Safety and Pharmacokinetics Evaluation of Fostemsavir + (OBT) in HIV-1 Infected Children and Adolescents Who Are Failing Their cART and Have Dual- or Triple-class Antiretroviral Resistance

HIV Infections With Multi Drug Resistant Virus

United States, South Africa, Mexico, Spain
Southeast University, China

Recruiting

Comparison of Epithelial Lining Fluid and Blood Pharmacokinetics and Pharmacodynamics of Intravenous and Intravenous Plus Nebulized Polymyxin B in Multidrug Resistant Bacteria Ventilator-associated Pneumonia Patients

Ventilator-associated Pneumonia | Multidrug Resistant Bacterial Infection | Polymyxin B | Pharmacogenomic Drug Interaction

China
Beijing Tiantan Hospital

Active, not recruiting

An Automated Navigation System for Deep Brain Electrode Implantation

Refractory Epilepsy | Obsessive-compulsive Disorder | Advanced Parkinson's Disease

China
National Institute of Allergy and Infectious Diseases...

Recruiting

A Trial of Anti-CD4 Antibody UB-421 in Combination With Optimized Background Antiretroviral Therapy in Patients With Multi-Drug Resistant HIV-1 Infection

Multi-Drug Resistant Hiv-1 Infection | HIV-1 Infection

United States
West China Hospital

Unknown

Docetaxel Versus Abiraterone as First-line Treatment in mCRPC Patients With Intraductal Carcinoma of the Prostate

Prostate Cancer | Castration-resistant Prostate Cancer | Drug
Bjorn H. Ebdrup

Completed

Treatment of Antipsychotic-associated Obesity With a GLP-1 Analogue (TAO)

Obesity | Schizophrenia | Metabolic Syndrome X | Drug-induced Obesity

Denmark
Mayo Clinic
National Cancer Institute (NCI)

Terminated

Perampanel for the Reduction of Seizure Frequency in Patients With High-grade Glioma and Focal Epilepsy

Malignant Glioma | WHO Grade 3 Glioma | Intractable Epilepsy | Seizure Disorder | WHO Grade 2 Glioma

United States
Ospedale Andrea Tortora di Pagani

Unknown

Evaluation of Cardiotoxicity and Hypertension in Patients With Non Metastatic Castration Resistant Prostatic Carcinoma (Apa-CARDIO1)

Castration-resistant Prostate Cancer

Italy
National Institute of Mental Health (NIMH)

Not yet recruiting

Natural History of Depression, Bipolar Disorder and Suicide Risk

Behavioral Symptoms | Suicide | Self-Injurious Behavior | Depressive Symptoms | Major Depressive Disorder | Treatment Resistant Depression | Ketamine | Molecular Mechanisms of Pharmacological Action | Depression, Unipolar | Depression, Bipolar | Physiological Effects of Drugs | Peripheral Nervous System Agents | Central Nervous System Depressants and other conditions

United States
Hospital Ruber Internacional
Zogenix, Inc.

Recruiting

Fenfluramine for the Treatment of Different Types of Developmental and Epileptic Encephalopathies: a Pilot Trial Exploring Epileptic and Non-epileptic Outcomes (FENDEEP)

Refractory Epilepsy | STXBP1 Encephalopathy With Epilepsy | SYNGAP1 Encephalopathy | Inv Dup(15) Encephalopathy | Multifocal or Bilateral Malformations of Cortical Development | Continuous Spike and Waves During Slow Sleep

Spain
Hospital Ruber Internacional

Recruiting

Galactose Supplementation for the Treatment of MOGHE (GATE)

Refractory Epilepsy | SLC35A2-CDG - Solute Carrier Family 35 Member A2 Congenital Disorder of Glycosylation

Spain
Yu-Li Hospital

Unknown

The Monitor of Serum Prolactin Level in a 3 Months Aripiprazole Trial

Schizophrenia, Tardive Dyskinesia, Metabolic Syndrome

Taiwan
Katarzyna Kotulska

Recruiting

Placebo Controlled Study to Assess the Efficacy and Safety of Rapamycin in Drug Resistant Epilepsy Associated With Tuberous Sclerosis Complex (RaRE-TS)

Tuberous Sclerosis Complex

Poland
Konya Numune Hospital

Completed

The Relationship Between Renal Functions and Multi Drug Resistant Organisms

Chronic Kidney Disease | Glomerular Filtration Rate | Drug Resistance

Turkey
Charite University, Berlin, Germany

Completed

Prospective Observational Pilot-study for the Evaluation of the Nephro- an Neurotoxicity in the Anti-infectious Therapy With Inhalative Colistin Therapy for Patients With Ventilator-associated Pneumonia (VAP) (LOKALE)

Infection Resistant to Multiple Drugs

Germany
Lawson Health Research Institute
Imperial College London; Queen's University; Northern Ontario School of Medicine

Completed

Efficacy Study of Panax Ginseng to Boost Antipsychotics Effects in Schizophrenia

Obesity | Schizophrenia | Schizoaffective Disorder | Insulin Resistance | Tardive Dyskinesia

Canada, United Kingdom

Clinical Trials on Extensively Drug Resistant Tuberculosis

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Mauritius

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Rare Diseases

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