Clinical Trials on Fatty Liver

Total 13431 results

BioMarin Pharmaceutical

Recruiting

A Study of BMN 255 in Participants With Non-Alcoholic Fatty Liver Disease And Hyperoxaluria

Nonalcoholic Fatty Liver Disease | Kidney Stone | Hyperoxaluria

United States
James King
University of Nottingham; Nottingham University Hospitals NHS Trust; University...

Completed

Diabetes, Exercise and Liver Fat (DELIVER) ((DELIVER))

Liver Diseases | Glucose Metabolism Disorders | Obesity | Diabetes Mellitus | Type 2 Diabetes Mellitus | Fatty Liver | Insulin Resistance | Glucose Intolerance | Non-Alcoholic Fatty Liver Disease | Metabolic Disease

United Kingdom
Ningbo No. 1 Hospital

Completed

Alcohol Consumption and Type 2 Diabetes Mellitus Risk in Nonalcoholic Fatty Liver Disease

Nonalcoholic Fatty Liver Disease | Type2 Diabetes Mellitus | Light-to-moderate Alcohol Consumption

China
University of Roma La Sapienza

Unknown

Prospective Clinical Study of the Role of the Immune Response, in Relation to Diet, in Patients Affected by Either Chronic Hepatitis C Virus (HCV) Infection or Non Alcoholic Fatty Liver Disease (NAFLD)

Non Alcoholic Fatty Liver Disease | Chronic Hepatitis C Virus

Italy
University of Sistan and Baluchestan
Niloofar Zareie Mohammad Zadeh

Completed

Hybrid Training and Middle Age

Metabolic Syndrome | Non-alcoholic Fatty Liver Disease | Women's Health | Middle Aged | Hybrid Training

Iran, Islamic Republic of
Histogen

Completed

Emricasan, an Oral Caspase Inhibitor, in Subjects With NASH Cirrhosis and Severe Portal Hypertension (ENCORE-PH)

Cirrhosis | Portal Hypertension | Non-alcoholic Steatohepatitis

United States, Germany, Spain
Hadassah Medical Organization
NasVax Ltd

Completed

Safety and Efficacy of Oral Administration of Anti-CD3 Monoclonal Antibody (mAb)in Patients With the Metabolic Syndrome

Nonalcoholic Steatohepatitis

Israel
First Affiliated Hospital Xi'an Jiaotong University

Not yet recruiting

Canagliflozin on Liver Inflammation Damage in Type 2 Diabetes Patients With Nonalcoholic Fatty Liver Disease

Type 2 Diabetes Mellitus With Complication
Shandong New Time Pharmaceutical Co., LTD

Completed

A Phase IV Study of Huazhi Rougan Granule

A Phase IV Trial to Investigate the Efficacy and Safety of Huazhi Rougan Granule in the Treatment of Non-alcoholic Simple Fatty Liver

China
Gilead Sciences

Completed

Pharmacokinetics and Pharmacodynamics of Cilofexor in Adults With Normal and Impaired Hepatic Function

Nonalcoholic Steatohepatitis (NASH) | Primary Sclerosing Cholangitis (PSC)

United States, New Zealand
Association pour la Recherche sur les Maladies...

Completed

A One-Year, Randomized, Double-Blind, Placebo-Controlled Trial of Rosiglitazone in Non-Alcoholic Steatohepatitis (FLIRT)

Non Alcoholic Steatohepatitis

France
Bettina Mittendorfer
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK); National...

Not yet recruiting

Harnessing Macrophage Lysosomal Lipid Metabolism in Obesity (ATM)

Healthy | Obesity | Diabetes Type 2 | Nonalcoholic Fatty Liver

United States
Metacrine, Inc.

Active, not recruiting

Study to Evaluate MET409 Alone or in Combination With Empagliflozin in Patients With Type 2 Diabetes and NASH

Diabetes | Fatty Liver | Type 2 Diabetes | NAFLD | NASH - Nonalcoholic Steatohepatitis | Diabetes Type 2 | NASH | Fatty Liver, Nonalcoholic

United States
Stanford University

Completed

Correlation of Ultrasound Based Measurements of Liver Stiffness and Steatosis With MRI

Liver Cirrhosis | Liver Steatoses

United States
King's College London

Unknown

Metabolic Surgery for Steato-Hepatitis (MeSH)

Non-alcoholic Fatty Liver Disease (NAFLD) | Non-Alcoholic Steato-Hepatitis (NASH)

United Kingdom
Ain Shams University

Not yet recruiting

Effect of CoQ10 on the Outcome of MAFLD Patients

Fatty Liver | NAFLD
Mayo Clinic

Completed

EUS Guided Core Liver Biopsy and IGB Placement for the Diagnosis and Management of NASH and Obesity

Obesity | Non-Alcoholic Steatohepatitis
University of Lorraine
Central Hospital, Nancy, France

Recruiting

Epigenetic Mechanisms and Severe Obesity (Biological Tissue Collection) (OBESEPI)

Metabolic Diseases | Obesity | Diabetes | Non-alcoholic Fatty Liver Disease

France
University of Sao Paulo

Unknown

Impact of Ketogenic Diet on Lipoproteins in Refractory Epilepsy (Ketonutri)

Epilepsy | Quality of Life | Cardiovascular Disease | Non-alcoholic Fatty Liver Disease

Brazil
Boehringer Ingelheim

Recruiting

A Study to Test Whether Survodutide Helps People Living With Obesity or Overweight and With a Confirmed or Presumed Liver Disease Called Non-alcoholic Steatohepatitis (NASH) to Reduce Liver Fat and to Lose Weight

Obesity | Non-Alcoholic SteatoHepatitis (NASH)

United States
Columbia University

Completed

Effect of Alpelisib in Healthy Volunteers

Insulin Resistance | Dyslipidemias | Hyperinsulinemia

United States
Imperial College London

Active, not recruiting

PET-MR Study of Fatty Liver (iDOSH)

Steatohepatitis

United Kingdom
Fudan University
Shanghai Changzheng Hospital; Shanghai 6th People's Hospital; Shanghai Minhang... and other collaborators

Completed

Exenatide Compared With Insulin Glargine to Change Liver Fat Content in Type 2 Diabetes

Diabetes Mellitus, Type 2 | Non-alcoholic Fatty Liver Disease

China
Universidade Federal do Rio de Janeiro
Rio de Janeiro State Research Supporting Foundation (FAPERJ)

Completed

Efficacy Study of Diacerein on Glycemic Control and Liver Fat in Type 2 Diabetes Subjects (DGCLFT2DM)

Diabetes Mellitus, Type 2 | Non-alcoholic Fatty Liver Disease

Brazil
Xin Gao
Pfizer

Unknown

Atorvastatin Versus Vitamin E in Treatment of Non-alcoholic Fatty Liver Disease

Diabetes Mellitus | Fatty Liver | Dyslipidemias

China
McGill University Health Centre/Research Institute...
CIHR Canadian HIV Trials Network

Completed

Nonalcoholic Steatohepatitis in HIV Mono-infection: Exploring Non-invasive Methods for Diagnosis and the Therapeutic Role of Vitamin E

HIV Mono Infection

Canada
University Hospital, Angers

Completed

Screening in Primary Care of Advanced Liver Fibrosis in NAFLD and/or Alcoholic Patients (IMPROVE Study) (IMPROVE)

NAFLD | Liver Fibrosis | Alcohol-Related Disorder

France
Assiut University

Not yet recruiting

Screening for Pancreatic Exocrine Insufficieny in Metabolic Associated Fatty Liver Disease Patients

Pancreatic Exocrine Insufficiency
The Deutsche Diabetes Forschungsgesellschaft e.V.
Boehringer Ingelheim

Completed

Effects of Empagliflozin on Liver Fat Content, Energy Metabolism and Body Composition in Patients With Type 2 Diabetes (EmLiFa)

Type 2 Diabetes | Non-alcoholic Fatty Liver Disease

Germany
University of Alabama at Birmingham

Completed

A Carbohydrate-restricted Diet to Reverse Fatty Liver in Adolescents With Obesity

Insulin Resistance | Non-alcoholic Fatty Liver Disease | Childhood Obesity

United States
Yonsei University

Completed

A 24 Week, Multicenter, Prospective, Open-labeled, Single-arm, Exploratory Phase 4 Clinical Trial to Evaluate the Safety and Efficacy of Lobeglitazone in Decreasing Intrahepatic Fat Contents in Type 2 Diabetes With NAFLD

Type 2 Diabetes | Non-alcoholic Fatty Liver Disease

Korea, Republic of
Stanford University
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Recruiting

Longitudinal Multi-Omic Profiles to Reveal Mechanisms of Obesity-Mediated Insulin Resistance

Obesity | Diabetes Mellitus, Type 2 | Insulin Resistance | PreDiabetes | Diet Modification | Nonalcoholic Steatohepatitis | Nonalcoholic Fatty Liver

United States
Corcept Therapeutics

Completed

Study to Evaluate the Effects of a Cytochrome P450 2C19 Inhibitor on the Pharmacokinetics of Miricorilant

Non-alcoholic Steatohepatitis (NASH) | Antipsychotic Induced Weight Gain

United States
Axcan Pharma

Completed

Pilot Study of Ursodesoxycholic Acid in Non-Alcoholic Steatohepatitis (URSONASH)

Serum Levels of ALAT Transaminases | Serum Markers for Fibrosis and Hepatic Inflammation

France
Humanity and Health Research Centre

Recruiting

Follow-up of Chronic Hepatitis B Patients With Comorbid Nonalcoholic Fatty Liver Disease

Chronic Hepatitis B | Nonalcoholic Fatty Liver Disease

China
Johns Hopkins University
ResMed Foundation

Completed

The Sleep, Liver Evaluation and Effective Pressure Study (SLEEP)

Obstructive Sleep Apnea | Non Alcoholic Fatty Liver Disease

United States
University of Toronto
Canadian Institutes of Health Research (CIHR); The Physicians' Services Incorporated... and other collaborators

Unknown

Meta-analyses of the Effect of Sucrose Versus High Fructose Corn Syrup on Cardiometabolic Risk

Hypertension | Obesity | Cardiovascular Disease | Dyslipidemia | Prediabetes | Gout | Non-Alcoholic Fatty Liver Disease | Dysglycemia

Canada
Franciscus Gasthuis
Erasmus Medical Center; Academisch Medisch Centrum - Universiteit van Amsterdam... and other collaborators

Not yet recruiting

The Franciscus Obesity NASH Study (FONS)

NAFLD | Obesity, Morbid | NASH - Nonalcoholic Steatohepatitis

Netherlands
University Hospital, Lille
Région Nord-Pas de Calais, France; RHU PreciNASH Task 1.4

Recruiting

Diagnostic Accuracy of the "LLIFT", a Novel Non-invasive Biomarker for the Diagnosis of Non Alcoholic Fatty Liver (NAFL) and SteatoHepatitis (NASH) in a Population With High Risk of Metabolic Syndrome" (LLIFT)

Obesity | NASH - Nonalcoholic Steatohepatitis

France
Perspectum
King's College Hospital NHS Trust; University of Coimbra; Liverpool University... and other collaborators

Completed

Non-invasive Rapid Assessment of NAFLD Using Magnetic Resonance Imaging With LiverMultiScan (RADIcAL1)

Metabolic Syndrome | NAFLD | NASH - Nonalcoholic Steatohepatitis

United Kingdom, Germany, Netherlands, Portugal
Indiana University School of Medicine

Terminated

Vitamin E for NASH Treatment in HIV Infected Individuals

HIV Infections | NAFLD | NASH - Nonalcoholic Steatohepatitis

United States
Fondazione Policlinico Universitario Agostino Gemelli...

Active, not recruiting

Fibrosis Reduction in Non Alcoholic Steatohepatitis (FRIN)

Weight Loss | Bariatric Surgery Candidate | NASH With Fibrosis

Italy
McMaster University
Neptune

Unknown

Omega-3 vs Very Low Calorie Diet for Liver Size Reduction

Obesity | NAFLD | Obesity, Morbid | NASH - Nonalcoholic Steatohepatitis
University of Iowa

Recruiting

Effect of VLCD on the Reduction of Liver Steatosis and Fibrosis in Subjects With Obesity and NAFLD

NAFLD

United States
Mayo Clinic
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Completed

Transforming Non-Invasive Liver Disease Detection by MRE: The Hepatogram

Obesity | Fatty Liver

United States
Neuraly, Inc.

Recruiting

A Phase 1 Study of DD01 in Overweight/Obese Subjects With T2DM and NAFLD

NAFLD | Overweight and Obesity | Type2 Diabetes

United States, Puerto Rico
University Hospital of Cologne

Unknown

24-h-ambulatory Blood Pressure Monitoring and Pulse Wave Analysis in NAFLD Patients (HyperNAFLD)

NAFLD; Hypertension, White-coat Hypertension, Masked Hypertension

Germany
Fondazione Policlinico Universitario Agostino Gemelli...

Active, not recruiting

DIAbetes and NAFLD (DIANA)

Diabetes | NAFLD | Fibrosis, Liver | Cirrhosis, Liver | Liver Cancer | NASH

Italy
Imperial College London
Novo Nordisk A/S

Completed

The Effect of Growth Hormone Replacement on Liver Fat

Fatty Liver | Growth Hormone, Recombinant

United Kingdom
Bram Brouwers
Dutch Diabetes Research Foundation

Completed

Optimizing the Beneficial Health Effects of Exercise for Diabetes: Focus on the Liver!

Obesity | Diabetes Mellitus, Type 2 | Non-alcoholic Fatty Liver Disease

Netherlands

Clinical Trials on Fatty Liver

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