Clinical Trials on Fetal Alcohol Spectrum Disorders

Total 8900 results

Akcea Therapeutics
Ionis Pharmaceuticals, Inc.

Completed

Study of ISIS 703802 in Participants With Hypertriglyceridemia, Type 2 Diabetes Mellitus, and Nonalcoholic Fatty Liver Disease

Diabetes Mellitus, Type 2 | NAFLD | Hypertriglyceridemia | Fatty Liver, Nonalcoholic

United States, Canada
Centre Hospitalier Universitaire de Saint Etienne
Ministry of Health, France

Completed

Influence of a Multi-parametric Optimization Strategy for General Anesthesia on Postoperative Morbidity and Mortality (OPTI-AGED)

Heart Failure | Stroke | Alcoholism | Diabetes | Cancer | Renal Insufficiency | Pulmonary Disease, Chronic Obstructive | Peripheral Vascular Diseases | Respiratory Insufficiency | Arrhythmias, Cardiac | Dementia | Coronary; Ischemic

France
University of Aarhus

Unknown

Characterization of Patients With Non-surgical Hypoparathyroidism and Pseudohypoparathyroidism

Pseudohypoparathyroidism | Idiopathic Hypoparathyroidism | Autosomal Dominant Hypocalcaemia

Denmark
St. Jude Children's Research Hospital
National Heart, Lung, and Blood Institute (NHLBI)

Terminated

Stroke With Transfusions Changing to Hydroxyurea

Hematologic Diseases | Anemia, Sickle Cell | Cerebrovascular Accident | Hemochromatosis

United States
The Deutsche Diabetes Forschungsgesellschaft e.V.
Boehringer Ingelheim

Completed

Effects of Empagliflozin on Liver Fat Content, Energy Metabolism and Body Composition in Patients With Type 2 Diabetes (EmLiFa)

Type 2 Diabetes | Non-alcoholic Fatty Liver Disease

Germany
Oramed, Ltd.
Integrium

Completed

A Study to Assess the Safety and Efficacy of Oral Insulin in T2DM Patients With Nonalcoholic Steatohepatitis (NASH)

Diabetes Mellitus, Type 2 | NASH - Nonalcoholic Steatohepatitis

United States, Israel
University of Missouri-Columbia
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK); American...

Completed

De Novo Lipogenesis in Severity of NAFLD

Obesity, Morbid | Bariatric Surgery Candidate | Nonalcoholic Fatty Liver Disease | Nonalcoholic Steatohepatitis

United States
Yonsei University

Completed

A 24 Week, Multicenter, Prospective, Open-labeled, Single-arm, Exploratory Phase 4 Clinical Trial to Evaluate the Safety and Efficacy of Lobeglitazone in Decreasing Intrahepatic Fat Contents in Type 2 Diabetes With NAFLD

Type 2 Diabetes | Non-alcoholic Fatty Liver Disease

Korea, Republic of
Azienda Ospedaliero-Universitaria di Modena

Recruiting

"Iron Overload and Endocrinological Diseases"

Iron Overload | Hemochromatosis | Thalassemia Major | Thalassemia Intermedia | Endocrinopathy

Italy
Haukeland University Hospital
Novartis

Withdrawn

Treatment of Iron Overload With Deferasirox (Exjade) in Hereditary Hemochromatosis and Myelodysplastic Syndrome (DefeHEMY)

Myelodysplastic Syndromes | Hemochromatosis

Norway
Boston Children's Hospital
Novartis

Completed

Pilot Study for Patients With Poor Response to Deferasirox

Sickle Cell Disease | Thalassemia Major | Transfusion-dependent Hemachromatosis

United States
German Diabetes Center

Recruiting

Metabolic Phenotyping and Follow-Up of Patients With and Without Diabetes After New Onset of STEMI (DISTEMI)

Diabetes Mellitus | Insulin Resistance | Non-Alcoholic Fatty Liver Disease | ST-segment Elevation Myocardial Infarction (STEMI)

Germany
Bettina Mittendorfer
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK); National...

Not yet recruiting

Harnessing Macrophage Lysosomal Lipid Metabolism in Obesity (ATM)

Healthy | Obesity | Diabetes Type 2 | Nonalcoholic Fatty Liver

United States
Karolinska University Hospital

Enrolling by invitation

Low Calorie Diet and Diabetes (LCD)

Obesity | Dyslipidemia | Non-alcoholic Fatty Liver Disease | Diabetes Mellitus Type 2

Sweden
University of Alabama at Birmingham

Recruiting

Pulmonary Function Using Non-invasive Forced Oscillometry (PUFFOR)

Infant, Newborn, Diseases | Infant, Premature, Diseases | Respiratory Distress Syndrome, Newborn | Bronchopulmonary Dysplasia | Meconium Aspiration Syndrome | Transient Tachypnea of the Newborn

United States
Benha University

Completed

Impact Of Maternal Spinal Anesthesia-Induced Hypotension At Scheduled Cesarean Delivery On Risk Development Of Transient Tachypnea Of Newborn And Fetal Acidosis

Transient Tachypnea of Newborn and Fetal Acidosis

Egypt
Kyowa Kirin Pharmaceutical Development Ltd

Completed

A Study to Describe the Lived Experience of XLH for Adolescents at End of Skeletal Growth

X-Linked Hypophosphatemia

France, United Kingdom, Spain, Germany, Netherlands
Kyowa Kirin, Inc.
Kyowa Kirin Co., Ltd.

Completed

Study of KRN23 in Adults With X-linked Hypophosphatemia (XLH)

X-linked Hypophosphatemia

United States, Korea, Republic of, Japan, Ireland, United Kingdom, France, Italy
Kyowa Kirin Co., Ltd.
Kyowa Hakko Kirin Pharma, Inc.

Completed

A Study of KRN23 in X-linked Hypophosphatemia

X-linked Hypophosphatemia

United States
Ultragenyx Pharmaceutical Inc
Kyowa Kirin Co., Ltd.

Available

Expanded Access to Burosumab

X-linked Hypophosphatemia | Tumor-Induced Osteomalacia
Kyowa Kirin, Inc.
Kyowa Kirin Co., Ltd.

Completed

Study of KRN23 (Burosumab), a Recombinant Fully Human Monoclonal Antibody Against Fibroblast Growth Factor 23 (FGF23), in Pediatric Subjects With X-linked Hypophosphatemia (XLH)

X-linked Hypophosphatemia

Netherlands, United States, United Kingdom, France
Orthopedic Hospital Vienna Speising

Completed

Foot Disorders in X-linked Hypophosphatemia

X-linked Hypophosphatemia

Austria
Yale University
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)

Completed

Calcitonin for Treating X-linked Hypophosphatemia

Hypophosphatemic Rickets, X Linked Dominant

United States
Assistance Publique - Hôpitaux de Paris

Not yet recruiting

Prevention of Spontaneous Dental Abscesses in Children With X-linked Hypophosphatemia : a RCT (PRADEX)

X-linked Hypophosphatemia (XLH)
Kyowa Kirin Co., Ltd.

Completed

A Study of KRN23 in Pediatric Patients With X-linked Hypophosphatemic Rickets/Osteomalacia

X-linked Hypophosphatemic Rickets/Osteomalacia

Japan
Inozyme Pharma
Engage Health Inc.; GACI Global

Completed

Understanding the Spectrum of ENPP1 Deficiency and Acute ABCC6 Deficiency

Generalized Arterial Calcification in Infancy | Autosomal Recessive Hypophosphatemic Rickets Type 2

United States
Children's Mercy Hospital Kansas City

Completed

Effect of Cinacalcet on Parathyroid Hormone Secretion in Children and Adolescents With Hypophosphatemic Rickets

Hypophosphatemic Rickets, X-Linked Dominant

United States
Kyowa Kirin Co., Ltd.

Completed

A Study of KRN23 in Subjects With X-linked Hypophosphatemic Rickets/Osteomalacia

X-linked Hypophosphatemic Rickets/Osteomalacia

Japan, Korea, Republic of
University of Aarhus

Completed

Characterising Pain, QoL, Body Composition, Arterial Stiffness, Muscles and Bones in Adult Persons With XLH and Healthy Controls

X-linked Hypophosphatemia | Hereditary Hypophosphatemia

Denmark
Kyowa Kirin Pharmaceutical Development Ltd

Completed

A UK Multicentre, Health-Related Quality of Life Study for Children and Adolescents With XLH

X-Linked Hypophosphataemia

United Kingdom
National Nutrition and Food Technology Institute

Completed

The Effects of Coffee Main Constituents (Caffeine and Chlorogenic Acid) Supplementation on Inflammatory, Metabolic Factors, Hepatic Steatosis and Fibrosis in None- Alcoholic Fatty Liver Patients With Type 2 Diabetes

Type 2 Diabetes Nonalcoholic Fatty Liver

Iran, Islamic Republic of
Mayo Clinic

Recruiting

Investigating the Link Between Type 2 Immunity and NAFLD in Human Obesity

Obesity, Morbid | Chronic Inflammation | NASH - Nonalcoholic Steatohepatitis

United States
University of Lorraine
Central Hospital, Nancy, France

Recruiting

Epigenetic Mechanisms and Severe Obesity (Biological Tissue Collection) (OBESEPI)

Metabolic Diseases | Obesity | Diabetes | Non-alcoholic Fatty Liver Disease

France
Shiraz University of Medical Sciences

Completed

Effects of Ginger on Nonalcoholic Fatty Liver Disease in T2DM (GinLivDM)

Diabetes Mellitus, Type 2 | Fatty Liver

Iran, Islamic Republic of
University of Sao Paulo

Unknown

Impact of Ketogenic Diet on Lipoproteins in Refractory Epilepsy (Ketonutri)

Epilepsy | Quality of Life | Cardiovascular Disease | Non-alcoholic Fatty Liver Disease

Brazil
Ziekenhuis Oost-Limburg

Active, not recruiting

Prevalence of NAFLD in T2DM Patients (PAD2ZOL)

Type 2 Diabetes | NAFLD | Fatty Liver, Nonalcoholic | T2D

Belgium
Xijing Hospital
Second Affiliated Hospital of Xi'an Jiaotong University; Shangluo Central Hospital and other collaborators

Completed

Efficacy of Pioglitazone Hydrochloride and Metformin Hydrochloride Tablets on the Patients With Newly Diagnosed Type 2 Diabetes Mellitus Combined With Non-alcoholic Fatty Liver Disease

Type 2 Diabetes Mellitus | Non-alcoholic Fatty Liver Disease | Efficacy

China
University of Florida

Terminated

RCT of Caloric Restriction vs. Alternate-Day Fasting in Non-Alcoholic Fatty Liver Disease

Obesity | Diabetes Mellitus, Type 2 | NAFLD

United States
Assistance Publique - Hôpitaux de Paris

Completed

Inhibitory rTMS in Dystonic Wilson Patients (WILSTIM)

Movement Disorders | Wilson Disease | Repetitive Transcranial Magnetic Stimulation

France
Ain Shams University

Unknown

Study Of Efficacy,Safety of Combined Deferasirox and Deferiprone Versus Combined Deferiprone and Desferal In Conditions of Iron Overload

Sickle Cell Disease | Beta-thalassemia Major | Iron Hemosiderosis

Egypt
Kyowa Kirin Co., Ltd.
Kyowa Kirin Co., Ltd.

Completed

A Repeated Study of KRN23 in Adults With X-Linked Hypophosphatemia

X-linked Hypophosphatemia

United States, Canada
Ultragenyx Pharmaceutical Inc
Kyowa Kirin Co., Ltd.

Active, not recruiting

X-linked Hypophosphatemia Disease Monitoring Program

X-linked Hypophosphatemia | Hypophosphatemic Rickets

United States, Brazil, Argentina, Canada, Chile, Colombia
Kyowa Kirin, Inc.
Kyowa Kirin Co., Ltd.

Completed

Long-Term Extension Study of KRN23 in Adult Subjects With X-Linked Hypophosphatemia (XLH)

X-Linked Hypophosphatemia

United States
Wuerzburg University Hospital
Kyowa Kirin, Inc.

Active, not recruiting

Burden of Disease and Functional Impairment in XLH (IdeFIX)

X Linked Hypophosphatemia

Germany
Bicetre Hospital

Unknown

Burosumab in Children and Adolescents With X-linked Hypophosphatemia

Rare Diseases | X-linked Hypophosphatemia

France
Redwood Dermatology Sciences
Ultragenyx Pharmaceutical Inc

Completed

Open Label Trial Assessing Safety and Efficacy of Burosumab (KRN23), in a Patient With ENS and Hypophosphatemic Rickets

Pain, Chronic | Hypophosphatemia | Hypophosphatemic Rickets

United States
Indiana University

Completed

Iron Therapy for Autosomal Dominant Hypophosphatemic Rickets: A Pilot Project.

Autosomal Dominant Hypophosphatemic Rickets

United States
LMC Diabetes & Endocrinology Ltd.

Recruiting

Clinical Outcomes From Enhanced SCREENing Strategies for NASH in Type 2 Diabetes (SCREEN NASH T2D)

Type 2 Diabetes | Nonalcoholic Steatohepatitis

Canada
Getz Pharma

Recruiting

Effect of Oral Anti-diabetic Medication on Liver Fat in Subjects With Type II Diabetes and Non-alcoholic Fatty Liver

Diabetes Mellitus, Type 2 | NAFLD | NASH - Nonalcoholic Steatohepatitis

Pakistan
The University of Texas Medical Branch, Galveston

Terminated

Fatty Liver Study in Patients With Type II Diabetes

Type II Diabetes | Nonalcoholic Fatty Liver

United States

Clinical Trials on Fetal Alcohol Spectrum Disorders

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