Clinical Trials on Fibrosis in United Kingdom

Total 2335 results

Manchester University NHS Foundation Trust

Completed

The Use of Novel Diagnostic Tools to Increase Detection of Early Fibrosis in Cystic Fibrosis Related Liver Disease to Improve Clinical Management

Cystic Fibrosis | Liver Fibroses | Cystic Fibrosis Liver Disease

United Kingdom
Royal Brompton & Harefield NHS Foundation Trust

Unknown

Assessment of Heart and Heart-Lung Transplant Patient Outcomes Following Pulmonary Rehabilitation

Lung Diseases | Bronchiectasis | Emphysema | Cystic Fibrosis | Alveolitis, Fibrosing

United Kingdom
Theravance Biopharma

Terminated

TD-1058 First-In-Human Study in Healthy Subjects and Subjects With Idiopathic Pulmonary Fibrosis

Idiopathic Pulmonary Fibrosis (IPF)

United Kingdom
Olympus Corporation of the Americas
Geisinger Clinic

Completed

The EUS ShearWave Elastography Liver Fibrosis Study

Liver Fibroses

United States
Royal Brompton & Harefield NHS Foundation Trust

Completed

Morphine Sulfate/Placebo for the Treatment of PulmonAry Fibrosis Cough (PAciFy Cough)

Idiopathic Pulmonary Fibrosis

United Kingdom
GlaxoSmithKline

Completed

A Proof of Mechanism Study With GSK2126458 in Patients With Idiopathic Pulmonary Fibrosis (IPF)

Idiopathic Pulmonary Fibrosis

United Kingdom
GlaxoSmithKline

Terminated

A Validation and Dosimetry Study of GSK2634673F PET Ligand

Idiopathic Pulmonary Fibrosis

United Kingdom
Kingston University
University College London Hospitals; St. George's Hospital, London

Completed

Toward Self-management in ILD

Idiopathic Pulmonary Fibrosis | Interstitial Lung Disease | Chronic Hypersensitivity Pneumonitis | Connective Tissue Related ILD | Fibrotic Lung Disease

United Kingdom
Blade Therapeutics

Withdrawn

Safety, Pharmacodynamics, and Pharmacokinetics of Orally Administered BLD-2660 in Subjects With IPF

Idiopathic Pulmonary Fibrosis

United Kingdom
GlaxoSmithKline

Terminated

Single Doses of GSK3008348 in Idiopathic Pulmonary Fibrosis (IPF) Participants Using Positron Emission Tomography (PET) Imaging

Idiopathic Pulmonary Fibrosis

United Kingdom
University of Nottingham
GlaxoSmithKline; McMaster University; Medical Research Council; CRAFT Consortium

Completed

Prospective Study of Fibrosis In the Lung Endpoints (PROFILE - Central England) (PROFILE)

Idiopathic Pulmonary Fibrosis

United Kingdom
GlaxoSmithKline

Completed

First Time in Human (FTIH) Study of GSK3008348 in Healthy Volunteers and Idiopathic Pulmonary Fibrosis Patients

Idiopathic Pulmonary Fibrosis

United Kingdom
Royal Brompton & Harefield NHS Foundation Trust
GlaxoSmithKline

Completed

IPF Drug Deposition Study (TOPICAL-IPF)

Idiopathic Pulmonary Fibrosis

United Kingdom
University of Michigan
Children's Hospital Medical Center, Cincinnati

Completed

Increased Liver Stiffness: A Study of Acoustic Radiation Force Impulse (ARFI) Elastography

Liver Fibroses

United States
Indalo Therapeutics, Inc.

Terminated

A Study of Safety & Blood Levels of IDL-2965 in Healthy Subjects and Patients With a Special Type of Pulmonary Fibrosis

Idiopathic Pulmonary Fibrosis | Healthy Volunteers

United Kingdom
Imperial College London
The Leeds Teaching Hospitals NHS Trust; Norfolk and Norwich University Hospitals... and other collaborators

Completed

Idiopathic Pulmonary Fibrosis Job Exposures Study (IPFJES)

Idiopathic Pulmonary Fibrosis | IPF

United Kingdom
Manchester University NHS Foundation Trust

Recruiting

Longitudinal Changes in Serum KL-6 in IPF (LOCK-IPF)

Idiopathic Pulmonary Fibrosis

United Kingdom
Royal Brompton & Harefield NHS Foundation Trust
National Institute for Health Research, United Kingdom

Completed

Responsiveness and MID of 4 Metre Gait Speed in Idiopathic Pulmonary Fibrosis (IPFRESP)

Idiopathic Pulmonary Fibrosis

United Kingdom
Royal Brompton & Harefield NHS Foundation Trust
National Institute for Health Research, United Kingdom

Completed

The Predictive Ability of 4MGS in IPF (IPFMORT)

Idiopathic Pulmonary Fibrosis

United Kingdom
Royal Brompton & Harefield NHS Foundation Trust
Kings Clinical Trials Unit

Completed

Muscle Stimulation in Advanced Idiopathic Pulmonary Fibrosis (MUST-IPF)

Idiopathic Pulmonary Fibrosis

United Kingdom
University Hospital Southampton NHS Foundation...

Unknown

Using Cardiovascular Magnetic Resonance Tissue Characterisation and Wearable Technology to PREDICT Clinical Outcomes, Response to Therapy and Arrhythmias in Hospitalised Heart Failure Patients (PREDICT-HF)

Heart Failure | Arrythmia | Diffuse Fibrosis | Focal Fibrosis

United Kingdom
Hepion Pharmaceuticals, Inc.

Active, not recruiting

Single Dose ADME Study of [14C]-Rencofilstat in Healthy Male Subjects

NASH With Fibrosis

United Kingdom
Raymond Chung
University of Texas Southwestern Medical Center

Recruiting

Safety and Efficacy of Atorvastatin v. Placebo on HCC Risk (TORCH)

Cirrhosis | Liver Fibroses

United States
University Hospitals Coventry and Warwickshire...

Unknown

Comparing Measurements Made in an Incremental Shuttle Walk Test and a Cardiopulmonary Exercise Test in Patients With IPF

Idiopathic Pulmonary Fibrosis

United Kingdom
University of East Anglia

Completed

Exhaled Breath Condensate Biomarkers and Cough in IPF

Idiopathic Pulmonary Fibrosis

United Kingdom
Royal Brompton & Harefield NHS Foundation Trust
National Institute for Health Research, United Kingdom

Completed

Reliability of the 4 Metre Gait Speed in Idiopathic Pulmonary Fibrosis (IPFREL)

Idiopathic Pulmonary Fibrosis

United Kingdom
Norfolk and Norwich University Hospitals NHS Foundation...
Norwich Clinical Trials Unit

Recruiting

Treating People With Idiopathic Pulmonary Fibrosis With the Addition of Lansoprazole (TIPAL)

Idiopathic Pulmonary Fibrosis

United Kingdom
Royal Brompton & Harefield NHS Foundation Trust

Active, not recruiting

Changes in iOS in IPF

Idiopathic Pulmonary Fibrosis

United Kingdom
Nottingham University Hospitals NHS Trust

Recruiting

Prospective Single Centre Observational Study to Compare the Diagnostic Yield of Different Modalities of Liver Biopsy

Liver Diseases | Liver Fibrosis

United Kingdom
University of Leeds
The Leeds Teaching Hospitals NHS Trust

Unknown

Functional MRI to Determine Severity of Cirrhosis

Liver Cirrhosis | Liver Fibrosis

United Kingdom
Manchester University NHS Foundation Trust
University of Nottingham; University of Manchester; Innovate UK

Recruiting

Integrated Diagnostics for Early Diagnosis of Liver Disease (ID LIVER)

Alcoholic Liver Disease | Non-Alcoholic Fatty Liver Disease | Non-alcoholic Steatohepatitis | Liver Fibroses

United Kingdom
University of Nottingham

Completed

Magnetic Resonance Imaging in the Evaluation of Liver Fibrosis (Mrker)

Liver Fibrosis

United Kingdom
Lung Therapeutics, Inc

Completed

Safety, Tolerability and Pharmacokinetic Study of LTI-03 in Healthy Adult Subjects

Idiopathic Pulmonary Fibrosis

United Kingdom
King's College Hospital NHS Trust
Samsung Medison

Recruiting

Effectiveness of Ultrasound in Liver Stiffness and Fat Quantification

Hepatitis | Liver Fat | NAFLD | Fibrosis, Liver | Liver Disease Chronic | Liver Steatoses | NASH With Fibrosis

United Kingdom
Hull University Teaching Hospitals NHS Trust
Chiesi Farmaceutici S.p.A.

Completed

Effect of Fostair® on Biomarkers of Platelet Adhesion in Idiopathic Pulmonary Fibrosis

Idiopathic Pulmonary Fibrosis

United Kingdom
University of Edinburgh
NHS Lothian

Completed

Novel MRI Strategies as a Non-invasive Biomarker in Women With Uterine Fibroids

Leiomyoma | Fibroid

United Kingdom
Children's Hospital Medical Center, Cincinnati

Terminated

Methods to Detect Liver Fibrosis

Hepatic Steatosis | Liver Fibroses

United States
Royal Brompton & Harefield NHS Foundation Trust
University of Nottingham; GlaxoSmithKline; University College, London

Completed

Prospective Observation of Fibrosis in the Lung Clinical Endpoints Study (PROFILE)

Idiopathic Pulmonary Fibrosis | Idiopathic Non-specific Interstitial Pneumonitis

United Kingdom
University of Portsmouth
University Hospital Southampton NHS Foundation Trust; Loughborough University; Queen Alexandra Hospital

Terminated

A CFit Study - Baseline

Cystic Fibrosis (CF) | Cystic Fibrosis-related Diabetes

United Kingdom
University of East Anglia
InterMune

Unknown

Modelling of Quality Life, Clinical and Physiological Measures in Idiopathic Pulmonary Fibrosis

Depression | Anxiety | Idiopathic Pulmonary Fibrosis | Dyspnoea

United Kingdom
Newcastle-upon-Tyne Hospitals NHS Trust
Newcastle University

Completed

Pilot Trial Of Omeprazole in Idiopathic Pulmonary Fibrosis (IPF) (PPIPF)

Idiopathic Pulmonary Fibrosis

United Kingdom
Owlstone Ltd
Clinical Research and Trials Unit (Norfolk & Norwich University Hospital,... and other collaborators

Not yet recruiting

Early Liver Disease Breath Detection

Liver Diseases | Liver Fibrosis | NASH

United Kingdom
Papworth Hospital NHS Foundation Trust
LifeArc

Not yet recruiting

Early Detection of Pulmonary Exacerbations in Non-cystic Fibrosis Bronchiectasis (Bronch-EX)

Non-cystic Fibrosis Bronchiectasis

United Kingdom
University College, London
National Institute for Health Research, United Kingdom

Recruiting

PentoxIfylline and Tocopherol for the Treatment of Post-radiotherapy Fibrosis in Head and Neck Cancer Patients (PITSTOP)

Head and Neck Fibrosis

United Kingdom
University of Oxford
Oxford University Hospitals NHS Trust

Completed

Oxygen Nanobubble Drink Impact on Exercise in Pulmonary Fibrosis

Pulmonary Fibrosis

United Kingdom
Liminal BioSciences Ltd.

Completed

A Healthy Volunteer Study of PBI-4050

Fibrosis | Inflammation

United Kingdom
University Hospital Southampton NHS Foundation...

Completed

Structured Exercise Training Programme in Idiopathic Pulmonary Fibrosis (Rehab-IPF)

Quality of Life | Idiopathic Pulmonary Fibrosis | Breathlessness

United Kingdom
University of Pennsylvania
National Cancer Institute (NCI)

Terminated

Impact of Transjugular Intrahepatic Portosystemic Shunts on Liver Stiffness

Portal Hypertension | Liver Fibroses

United States
Renovo

Unknown

Juvista (Avotermin) in the Prevention or Improvement of Scar Appearance Following Scar Revision Surgery.

Cicatrix

United Kingdom
Imperial College London

Completed

Auto-titrating Oxygen in Chronic Respiratory Failure (ASI1)

Chronic Obstructive Pulmonary Disease | Idiopathic Pulmonary Fibrosis

United Kingdom

Clinical Trials on Fibrosis in United Kingdom

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