Clinical Trials on Focal Seizure in Italy

Total 115 results

Neurocrine Biosciences

Terminated

Extension Study to Evaluate the Safety and Tolerability of NBI-921352 When Used With Anti-seizure Medications in Adults With Focal Onset Seizures

Focal Onset Seizure | Focal Onset Epilepsy

Spain, Australia, Belgium, Czechia, France, Hungary, Italy
Neurocrine Biosciences

Completed

A Study to Investigate How Effective, Safe and Tolerable the Drug NBI-921352 is When Used With Anti-seizure Medications in Adults With Focal Onset Seizures

Focal Onset Seizure | Focal Onset Epilepsy

Spain, Belgium, Czechia, France, Italy, Australia, Hungary, United Kingdom
Aziende Chimiche Riunite Angelini Francesco S.p.A
Iqvia Pty Ltd

Recruiting

Cenobamate in Adults With Focal-Onset Seizures (BLESS)

Epilepsy | Neurological Disorder | Focal-Onset Seizure

Italy
Fondazione IRCCS Ca' Granda, Ospedale Maggiore...

Active, not recruiting

Neonatal Seizures: Semiology, Etiology, Therapy and Prognosis Correlations

Epilepsy | Neonatal Seizure

Italy
Xenon Pharmaceuticals Inc.
Worldwide Clinical Trials

Recruiting

A Randomized Study of XEN1101 Versus Placebo in Focal-Onset Seizures (X-TOLE3)

Focal Onset Seizures

United States, Spain, Italy, Croatia, Portugal, Poland, Chile, Argentina, Austria, Czechia
Jazz Pharmaceuticals

Completed

A Study of GWP42006 in People With Focal Seizures - Part B

Epilepsy | Focal Seizures

Italy, Poland, United Kingdom, Spain, Hungary, Czechia
Xenon Pharmaceuticals Inc.
Worldwide Clinical Trials

Recruiting

A Randomized Study of XEN1101 Versus Placebo in Focal-Onset Seizures (X-TOLE2)

Focal Onset Seizures

United States, Spain, Australia, Poland, Canada, Bulgaria, Italy, United Kingdom
Neuromed IRCCS

Recruiting

NEED: Neuromed Epilepsy EEG Database. A Large EEG Database of Epilepsy Patients for Research Community. (NEED)

Automatic Seizure Detection

Italy
Pfizer

Completed

To Evaluate Long-Term Safety and Efficacy of Pregabalin in Patients With Partial Seizures.

Seizure Disorder, Partial

Spain, France, Italy, Australia, United Kingdom, Germany, Belgium, Netherlands, Austria, Sweden, Finland, South Africa, Switzerland
UCB Biopharma S.P.R.L.

Completed

Study to Test the Efficacy and Safety of Padsevonil as Adjunctive Treatment of Focal-onset Seizures in Adults With Drug-resistant Epilepsy (ARISE)

Focal-Onset Seizures | Drug-resistant Epilepsy

United States, Australia, Belgium, Bulgaria, Canada, Czechia, France, Germany, Hungary, Italy, Japan, Lithuania, Mexico, Poland, Portugal, Slovakia, Spain, Turkey, United Kingdom
UCB Biopharma SRL

Terminated

A Study to Test the Efficacy and Safety of Padsevonil as Treatment of Focal-onset Seizures in Adult Subjects With Drug-resistant Epilepsy (DUET)

Drug-Resistant Epilepsy | Focal-Onset Seizures

United States, Australia, Belgium, Bosnia and Herzegovina, Bulgaria, Croatia, Czechia, Denmark, Estonia, Finland, France, Germany, Greece, Hungary, Ireland, Italy, Japan, Norway, Poland, Portugal, Romania, Serbia, Slovakia, Spain, Sweden, Switzerlan... and more
UCB Biopharma SRL

Terminated

Study to Test the Safety and Efficacy of Padsevonil as Adjunctive Treatment of Focal-onset Seizures in Adult Subjects With Drug-resistant Epilepsy

Drug-Resistant Epilepsy | Focal-Onset Seizures

United States, Australia, Belgium, Bosnia and Herzegovina, Bulgaria, Canada, Croatia, Czechia, Denmark, Estonia, Finland, France, Germany, Greece, Hungary, Ireland, Italy, Japan, Lithuania, Mexico, Poland, Romania, Serbia, Slovakia, Spain, Turk... and more
Fondazione Policlinico Universitario Agostino Gemelli...

Completed

Ropivacaine Plasma Concentration With or Without Epinephrine for Posterior Quadratus Lumborum Block

Anesthesia, Local | Local Anesthetic Systemic Toxicity

Italy
San Salvatore Hospital of L'Aquila

Completed

Anesthetic Efficacy of PECS II Block and Parasternal Block

Anesthesia, Local

Italy
University of Campania "Luigi Vanvitelli"

Completed

Efficacy of Differents Anaesthetics in Mandibular Third Molar Germectomy

Local Anesthetic Efficacy

Italy
Xenon Pharmaceuticals Inc.

Terminated

XEN496 (Ezogabine) in Children With KCNQ2 Developmental and Epileptic Encephalopathy (EPIK)

Brain Diseases | Central Nervous System Diseases | Nervous System Diseases | Epilepsy | Epileptic Syndromes | Disease | Epilepsy; Seizure | Epilepsy in Children

United States, Spain, Australia, Belgium, Italy
European e-Learning School in Obstetric Anesthesia

Completed

Epidural Catheter Location by Epidural Pressure Waveform

Anesthesia, Local

Italy
Eisai Limited

Completed

A Study to Assess the Efficacy and Safety of Adjunctive Zonisamide in Paediatric Partial Onset Seizures (CATZ Extension Study)

Partial Seizures

Italy
San Salvatore Hospital of L'Aquila

Recruiting

Thoracic Intervertebral Foramen Block

Anesthesia, Local | Anesthesia; Functional | Spinal Cord

Italy
Istituto Ortopedico Rizzoli

Completed

Impatto Emodinamico Dell'Anestesia Subaracnoidea Titrata Versus Tecnica Single-shot Nei Pazienti Sottoposti ad Artroprotesi d'Anca. RCT (NINO)

Anesthesia, Local | Anesthesia; Adverse Effect

Italy
Mario Negri Institute for Pharmacological Research
Agenzia Italiana del Farmaco

Completed

Rituximab in Multirelapsing Minimal Change Disease (MCD) or Focal Segmental Glomerulosclerosis (FSGS) (NEMO)

Nephrotic Syndrome

Italy
Genzyme, a Sanofi Company

Completed

Safety Study of GC1008 in Patients With Focal Segmental Glomerulosclerosis (FSGS) of Single Doses of GC1008 in Patients With Treatment Resistant Idiopathic FSGS

Focal Segmental Glomerulosclerosis

United States, Germany, United Kingdom, Italy
Genzyme, a Sanofi Company

Completed

A Study of Fresolimumab in Patients With Steroid-Resistant Primary Focal Segmental Glomerulosclerosis (FSGS) (FSGS)

Primary Focal Segmental Glomerulosclerosis

United States, Brazil, Germany, Italy, Spain
Azienda Ospedaliero Universitaria Maggiore della...

Unknown

Evaluation of Laryngeal Morbidity After Orotracheal Intubation by Vocal Analysis and Laryngostroboscopy

Intubation Complication | Vocal Cord Dysfunction | Intubation;Difficult | Vocal Tone Disorder

Italy
Regina Elena Cancer Institute

Recruiting

Prognostic Relevance of Coagulation Activation in RIsk Assessment and Stratification (ARIAS)

Local Cancer

Italy
Zogenix International Limited, Inc., a subsidiary...

Completed

A Trial of Two Fixed Doses of ZX008 (Fenfluramine HCl) in Children and Young Adults With Dravet Syndrome

Dravet Syndrome | Seizure Disorder

United States, United Kingdom, Australia, Belgium, Canada, Denmark, France, Germany, Italy, Japan, Spain
IRCCS San Raffaele

Not yet recruiting

Cognitive Impairment in Drug-resistant and Drug-responsive Focal Cryptogenic Epilepsy

Epilepsy | Focal Epilepsy

Italy
University of Roma La Sapienza
Ipsen

Unknown

Motor and Non-motor Symptoms in Cervical Dystonia (Royal)

Dystonia, Focal

Italy
Eisai Inc.

Completed

Evaluation of the Efficacy and Safety of Adjunctive Zonisamide vs Replacement With Zonisamide of the Last Added Antiepileptic Drug

Partial Seizures

Italy
Fondazione Policlinico Universitario Agostino Gemelli...

Completed

Voice Telerehabilitation

Vocal Fold Palsy

Italy
Meyer Children's Hospital
IRCCS Azienda Ospedaliero-Universitaria di Bologna; Azienda Ospedaliera Universitaria... and other collaborators

Terminated

Ketamine in Refractory Convulsive Status Epilepticus (KETASER01)

Status Epilepticus

Italy
Fondazione Policlinico Universitario Agostino Gemelli...

Recruiting

Non-phonatory Exercises in Patients With Unilateral Vocal Fold Paralysis Post-thyroidectomy (ENFP)

Unilateral Vocal Cord Paralysis

Italy
UCB Biopharma SRL

Terminated

A Study to Test the Pharmacokinetics, Efficacy, and Safety of Brivaracetam in Newborns With Repeated Electroencephalographic Seizures

Electroencephalographic Neonatal Seizures

Belgium, France, Germany, Ireland, United Kingdom, Czechia, Italy
Azienda Sanitaria-Universitaria Integrata di Udine

Completed

Propofol-remifentanyl Versus Dexmedetomidine in Awake Craniotomy: Impact on Electroclinical Seizure Activity

Seizures | Dexmedetomidine | Craniotomy | Propofol | Remifentanil | Cerebral Tumor | Neurophysiology

Italy
Aziende Chimiche Riunite Angelini Francesco S.p.A
Hippocrates Research

Recruiting

Adjunctive Anti-seizure Medication (ASM) Real World Evidence (RWE) Study

Epilepsy

Italy
Maastricht University Medical Center

Completed

Percutaneous Tibial Nerve Stimulation in the Treatment of Fecal Incontinence

Fecal Incontinence

Netherlands, France, Italy
Pfizer

Terminated

A Study to Evaluate PF-06730512 in Adults With Focal Segmental Glomerulosclerosis (FSGS) (PODO)

Focal Segmental Glomerulosclerosis (FSGS)

United States, Spain, Czechia, Canada, France, Germany, United Kingdom, Poland, Japan, Mexico, Italy, Slovakia
University of Padova

Withdrawn

Comparison of Erector Spinae Plane Block With PECS II Block in Patients Undergoing Breast Cancer Surgery

Breast Cancer | Anesthesia, Local

Italy
Jazz Pharmaceuticals

Terminated

Efficacy and Safety of GWP42003-P Oral Solution in Children With Epilepsy With Myoclonic-atonic Seizures

Seizures Associated With EMAS

United States, Italy
University of Turin, Italy

Recruiting

Ropivacaine Plasma Concentrations After Fascial Blocks in Elective Cardio-thoracic and Abdominal Surgery

Postoperative Pain | Regional Anesthesia Morbidity | Local Anesthetic Toxicity

Italy
University of Padova

Recruiting

ESP Block Versus Wound Infiltration for Laminectomy

Pain, Postoperative | Anesthesia, Local | Surgery | Opioid Use

Italy
Empatica, Inc.

Active, not recruiting

Generalized Seizure Detection And Alerting In The EMU With The Empatica Embrace Watch And Smartphone-Based Alert System

Epilepsy

United States, Italy
Eisai Limited

Terminated

A Study to Evaluate the Safety and Tolerability and Explore the Efficacy of Zonisamide as add-on Therapy in Elderly Patients With Refractory Partial Seizures

Epilepsy

United Kingdom, Germany, Hungary, Switzerland, Italy, Netherlands, Poland
Fondazione Policlinico Universitario Agostino Gemelli...

Completed

Erector Spinae Plane Block (ESPB) Versus Quadratus Lumborum Block (QLB) for Postoperative Analgesia After Caesarean Section

Anesthesia, Local | Cesarean Section Complications | Pain, Post Operative | Obstetric Anesthesia Problems

Italy
Xenon Pharmaceuticals Inc.
Worldwide Clinical Trials

Recruiting

A Study to Evaluate XEN1101 as Adjunctive Therapy in Primary Generalized Tonic-Clonic Seizures (X-ACKT)

Primary Generalized Tonic-Clonic Seizures

United States, Australia, Spain, United Kingdom, Bulgaria, Poland, Czechia, Canada, Portugal, Croatia, Italy
Sándor Beniczky
University of Pavia; Thomas Jefferson University; Shiraz University of Medical... and other collaborators

Completed

Validation Study of the Simplified Seizure Classification Algorithm (VASSCA)

Epilepsy

United States, Iran, Islamic Republic of, Denmark, Italy
Travere Therapeutics, Inc.

Completed

Randomized, Double-Blind, Safety and Efficacy Study of RE-021 (Sparsentan) in Focal Segmental Glomerulosclerosis (DUET)

Focal Segmental Glomerulosclerosis

United States, Italy, Czechia
MaaT Pharma

Completed

Treatment of Steroid Refractory Gastro-intestinal Acute GVHD afteR AllogeneiC HSCT With fEcal Microbiota tranSfer (HERACLES)

Fecal Microbiota Transplantation

France, Italy, Poland
Ospedale Misericordia e Dolce

Unknown

Single Dose Steroid Before Thyroidectomy for Benign Disease to Improve Postoperative Nausea, Pain, and Vocal Function

Postoperative Pain | Thyroidectomy | Postoperative Nausea and Vomit | Postoperative Vocal Function

Italy
ChemoCentryx
Medpace, Inc.

Completed

A Study of CCX140-B in Subjects With FSGS

Focal Segmental Glomerulosclerosis | FSGS | Glomerulosclerosis

United States, France, Italy, Australia, United Kingdom, Canada, New Zealand, Poland

Clinical Trials on Focal Seizure in Italy

Sponsors and Collaborators

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