Clinical Trials on Gastric Cardia Adenocarcinoma

Total 20828 results

Shanghai Zhongshan Hospital

Not yet recruiting

Synergistic Effects of PD-1 Antibody and Chemotherapy Followed by Surgery in Limited-metastatic G/GEJ Adenocarcinoma (ROSETTE)

Gastric Cancer | GastroEsophageal Cancer

China
Royal Marsden NHS Foundation Trust
Gilead Sciences

Not yet recruiting

Peri-operative Zimberelimab (Anti-PD-1) vs Zimberelimab in Combination With Domvanalimab (Anti-TIGIT) in Resectable Mismatch Repair Deficient/Micro-satellite Unstable Gastric and Gastro-oesophageal Junctional Adenocarcinoma (ZODIAC) (ZODIAC)

Metastatic Gastric Cancer | Metastatic Esophageal Cancer
Arbele Pty Ltd

Recruiting

Treatment of Cabotamig (ARB202) in Advanced Gastrointestinal Cancer Patients

Gastric Cancer | Pancreatic Cancer | Cholangiocarcinoma | Esophageal Adenocarcinoma | Gastrointestinal Cancer | Liver Cancer | Colorectal Adenocarcinoma | Gastroesophageal Junction

Hong Kong, Australia
MedImmune LLC

Completed

A Phase 1b/2 Study of MEDI4736 With Tremelimumab, MEDI4736 or Tremelimumab Monotherapy in Gastric or GEJ Adenocarcinoma

Gastric or Gastroesophageal Junction Adenocarcinoma

Canada, United States, Taiwan, Korea, Republic of, Japan, Singapore
MedImmune LLC

Completed

A Study to Evaluate the Safety and Tolerability of MEDI-565 in Adults With Gastrointestinal Adenocarcinomas

Gastrointestinal Adenocarcinomas

United States
Leap Therapeutics, Inc.
Merck Sharp & Dohme LLC

Completed

A Study of DKN-01 in Combination With Paclitaxel or Pembrolizumab (P102)

Esophageal Neoplasms | Gastric Adenocarcinoma | Adenocarcinoma of the Gastroesophageal Junction | Squamous Cell Carcinoma | Gastroesophageal Cancer

United States
Peking University
Chia Tai Tianqing Pharmaceutical Group Co., Ltd.

Not yet recruiting

Anlotinib, TQB2450 (PD-L1 Inhibitor), and Albumin-bound Paclitaxel Regimens in the Treatment of GC/GEJA

Gastric Cancer | Adenocarcinoma of Esophagogastric Junction

China
Novartis Pharmaceuticals

Completed

A Phase II Study to Evaluate Efficacy and Safety of Dovitinib (TKI258) in Advanced Scirrhous Gastric Carcinoma Patients

Neoplasms | Neoplasms by Site | Stomach Neoplasms | Stomach Diseases | Adenocarcinoma, Scirrhous | Linitis Plastica

Japan
Fujian Medical University

Not yet recruiting

Study Evaluating Neoadjuvant Immunotherapy Increasing CD8+ Cell Infiltration in Advance Gastric Adenocarcinoma

Advanced Gastric Carcinoma | Neoadjuvant Immunotherapy | CD8+ Tumor Infiltrating Lymphocytes
University Hospital, Essen
GWT-TUD GmbH

Active, not recruiting

Perioperative Immunotherapy vs. Chemo-immunotherapy in Patients With Advanced GC and AEG (IMAGINE)

Gastric Cancer | Adenocarcinoma of the Esophagogastric Junction

Germany
iOMEDICO AG

Recruiting

Registry Platform Gastric/Esophageal Cancer (SAPHIR) (SAPHIR)

Gastric Adenocarcinoma | Esophageal Adenocarcinoma | Esophageal Squamous Cell Carcinoma | Gastroesophageal Junction Adenocarcinoma

Germany
Cancer Trials Ireland
Southampton Clinical Trials Unit; Region H Rigshospitalet; Centre Hospitalier...

Completed

NEOadjuvant Trial in Adenocarcinoma of the oEsophagus and oesophagoGastric Junction International Study (Neo-AEGIS)

Oesophageal Cancer | Adenocarcinoma of the Oesophagus | Adenocarcinoma of the Oesophago-gastric Junction | Oesophageal Tumours | Junctional Tumours

Ireland, United Kingdom, Denmark, France, Sweden
Wu Jun

Not yet recruiting

Efficacy and Safety of Sintilimab Combined With Nab-paclitaxel and Tegio (aTS) as First-line Treatment of Unresectable Locally Advanced, Recurrent or Metastatic Adenocarcinoma of Gastric and Gastroesophageal Junction，a Phase II Clinical Study

Adenocarcinoma | Gastric Cancer | GastroEsophageal Cancer

China
The First Hospital of Jilin University

Recruiting

A Prospective, Single Center Clinical Study of Toripalimab Combined With FLOT Regimen for Perioperative Treatment of PD-L1 Positive Locally Advanced Resectable Gastric Cancer or Gastroesophageal Junction Adenocarcinoma (GEJ)

PD-L1 Positive Locally Advanced Patients With Resectable Gastric Cancer

China
Sixth Affiliated Hospital, Sun Yat-sen University

Recruiting

Docetaxel, Oxaliplatin and 5-FU for Gastric Cancer With Inoperable Malignant Bowel Obstruction

Peritoneal Carcinomatosis | Metastatic Gastric Adenocarcinoma | Metastatic Gastroesophageal Junction Adenocarcinoma

China
Ashwin Somasundaram
EMD Serono; University of North Carolina, Chapel Hill

Completed

Trial of mFOLFOX6 + Trastuzumab + Avelumab in Gastric and Esophageal Adenocarcinomas

Gastric Adenocarcinoma | Metastasis | Esophageal Adenocarcinoma | HER-2 Gene Amplification

United States
Gulam Manji
Merck Sharp & Dohme LLC

Completed

Perioperative Chemo and Pembrolizumab in Gastric Cancer

Gastric Cancer | Adenocarcinoma of the Gastroesophageal Junction

United States
Apollo Therapeutics Ltd

Not yet recruiting

A Study to Investigate APL-5125 in Adults With Advanced Solid Tumors

Colorectal Cancer | Pancreatic Adenocarcinoma | Ovarian Cancer | Prostate Cancer | Gastric Adenocarcinoma | Cholangiocarcinoma | Triple Negative Breast Cancer | Endometrial Adenocarcinoma | Appendiceal Adenocarcinoma
H. Lee Moffitt Cancer Center and Research Institute

Terminated

Selinexor in Combination With Irinotecan in Adenocarcinoma of Stomach and Distal Esophagus

Gastric Cancer | Esophageal Cancer

United States
Hvidovre University Hospital

Unknown

Band to Bypass - Metabolism Kinetics in Gastric Bypass and Banding

Gastric Bypass | Gastric Banding

Denmark
AstraZeneca

Recruiting

AZD0901 in Participants With Advanced Solid Tumours Expressing Claudin18.2

Gastric Cancer | Pancreatic Adenocarcinoma | Gastroesophageal Junction Cancer

United States, Spain, United Kingdom, Korea, Republic of, Canada, Japan, Malaysia, Taiwan, Singapore, Moldova, Republic of, Australia, Poland, Georgia
Washington University School of Medicine
Xcovery Holding Company, LLC

Terminated

Vorolanib (X-82) Combined With Checkpoint Inhibitors in Patients With Solid Tumors

Hepatocellular Carcinoma | Gastric Cancer | Solid Tumor | Gastroesophageal Junction Adenocarcinoma

United States
Guangdong Zhongsheng Pharmaceutical Co., Ltd.

Unknown

A Phase 1 Study of ZSP1241 in Participants With Advanced Solid Tumors

Hepatocellular Carcinoma | Gastric Cancer | Colorectal Cancer | Esophageal Cancer | Cholangiocarcinoma

China
Eli Lilly and Company

No longer available

Ramucirumab Use in Combination With Paclitaxel in Gastric or Gastroesophageal Junction Adenocarcinoma; Temporary Authorization for Use (ATU) in France

Gastric Cancer | Gastroesophageal Junction Adenocarcinoma
Stony Brook University
University of Iowa; Ipsen; Barbara Ann Karmanos Cancer Institute

Completed

Phase I Trial HIPEC With Nal-irinotecan

Gastric Cancer | Colorectal Cancer | Mesothelioma | Pseudomyxoma Peritonei | Peritoneal Cancer | Mucinous Adenocarcinoma | Primary Peritoneal Carcinoma | Mucinous Tumor

United States
I-Mab Biopharma Co. Ltd.

Recruiting

Study of TJ033721 in Subjects With Advanced or Metastatic Solid Tumors

Gastric Cancer | Solid Tumor | Metastatic Cancer | Advanced Cancer | Esophageal Adenocarcinoma | Gastroesophageal Junction Carcinoma

United States, China
Hoffmann-La Roche

Terminated

A Study to Explore the Efficacy and Safety of Atezolizumab Plus Tiragolumab and Chemotherapy in 1st Line HER2 Negative Unresectable, Recurrent or Metastatic Gastric Cancer or Adenocarcinoma of Gastroesophageal Junction (GEJ)

Stomach Neoplasms | Gastric Cancer | Gastroesophageal Junction Adenocarcinoma

China
University of Washington
National Center for Complementary and Integrative Health (NCCIH); National...

Recruiting

Feasibility of Auricular Acupressure for Appetite and Weight in Patients With Stage II-IV Gastric, Esophageal, and Pancreatic Cancer

Stage II Pancreatic Cancer AJCC v8 | Stage III Pancreatic Cancer AJCC v8 | Stage IV Pancreatic Cancer AJCC v8 | Clinical Stage III Gastric Cancer AJCC v8 | Clinical Stage IV Gastric Cancer AJCC v8 | Clinical Stage II Esophageal Adenocarcinoma AJCC v8 | Clinical Stage II Esophageal Squamous Cell... and other conditions

United States
Merck Sharp & Dohme LLC

Active, not recruiting

Study of Pembrolizumab (MK-3475) Plus Chemotherapy Versus Placebo Plus Chemotherapy in Participants With Gastric or Gastroesophageal Junction (GEJ) Adenocarcinoma (MK-3475-585/KEYNOTE-585)

Gastric Cancer | Gastroesophageal Junction Cancer

United States, Belgium, Brazil, Canada, Chile, China, Estonia, France, Germany, Guatemala, Israel, Italy, Japan, Korea, Republic of, Latvia, Lithuania, Malaysia, Philippines, Poland, Russian Federation, Singapore, Taiwan, Ukraine, United...
Nanchong Central Hospital

Recruiting

Proximal Gastrectomy Anterior Anastomosis With Pyloroplasty Versus Esophagogastric Anastomosis for Gastric Cancer

Gastric Cancer | Gastroesophageal Reflux Disease | Proximal Gastric Adenocarcinoma

China
Johannes Gutenberg University Mainz
AIO-Studien-gGmbH

Completed

Efficacy of Cetuximab in Combination With Irinotecan and 5- FU/FA in Treatment of Metastatic Gastric Cancer (GC-CIF-2005)

Adenocarcinoma of Stomach or Esophagogastric Junction

Germany
Western Sydney Local Health District

Recruiting

The Australia and New Zealand Multicentre Upper Gastrointestinal Endoscopic Tissue Resection Study (ANZ UGI)

Gastric Cancer | Esophageal Neoplasms | Neuroendocrine Tumors | Gastric Adenocarcinoma | Cancer of Stomach | Oesophageal Cancer | Gastric Neoplasm | GIST | GI Cancer

Australia
Merck Sharp & Dohme LLC

Active, not recruiting

Study of Pembrolizumab (MK-3475) Plus Chemotherapy Versus Placebo Plus Chemotherapy in Participants With Gastric or Gastroesophageal Junction (GEJ) Adenocarcinoma (MK-3475-585/KEYNOTE-585)-China Extension

Gastric Cancer | Gastroesophageal Junction Cancer

China
Memorial Sloan Kettering Cancer Center
Weill Medical College of Cornell University; McMaster University

Completed

Impact of Roux-En-Y Pouch Reconstruction Compared With Conventional Roux-En-Y Reconstruction on Health-Related Quality of Life in Patients Undergoing Total Gastrectomy for Adenocarcinoma

Gastric Cancer

United States
University of Roma La Sapienza
Andrea Laghi

Active, not recruiting

Radiomics and Molecular Expression Predictive Model for Esophago-Gastric Junction and Gastric Cancer TRG

Gastric Cancer | Adenocarcinoma of the Stomach

Italy, Netherlands
Curegenix Inc.
Guangzhou Curegenix Co. Ltd.

Unknown

Phase 1 Dose Escalation Study of CGX1321 in Subjects With Advanced Gastrointestinal Tumors

Hepatocellular Carcinoma | Pancreatic Adenocarcinoma | Gastric Adenocarcinoma | Gastrointestinal Cancer | Esophageal Carcinoma | Colorectal Adenocarcinoma | Bile Duct Carcinoma

China
Boehringer Ingelheim

Recruiting

Beamion BCGC-1: A Study to Find a Suitable Dose of Zongertinib in Combination With Trastuzumab Deruxtecan or With Trastuzumab Emtansine and to Test Whether it Helps People With Different Types of HER2+ Cancer That Has Spread

Metastatic Breast Cancer | Esophageal Adenocarcinoma | Metastatic Gastric Adenocarcinoma | Gastroesophageal Junction Adenocarcinoma

United States
Grupo Espanol Multidisciplinario del Cancer Digestivo

Completed

Study of Oxaliplatin and Sorafenib Combination to Treat Gastric Cancer Relapsed After a Cisplatin Based Treatment

Advanced or Metastatic Gastric or Gastroesophageal Junction Adenocarcinoma (Relapsed After a Cisplatin Based Treatment)

Spain
Zhejiang Provincial People's Hospital
Zhejiang University; Hangzhou RonGu Biotechnology Limited Company

Not yet recruiting

Clinical Study of Cord Blood-Derived CAR-NK Cells in Gastric Cancer and Pancreatic Cancer

Gastric Cancer | Pancreas Adenocarcinoma

China
Memorial Sloan Kettering Cancer Center
Merck Sharp & Dohme LLC; Genentech, Inc.

Recruiting

A Study of Pembrolizumab With Trastuzumab and Chemotherapy in People With Esophagogastric Cancer

Esophageal Cancer | Gastric Adenocarcinoma | HER2 Gene Mutation

United States
SOFIE

Recruiting

Study of [18F]FAPI-74 PET in Patients With Gastrointestinal Cancers (18F-FAPI-74 GI)

Hepatocellular Carcinoma | Gastric Cancer | Colorectal Cancer | Cholangiocarcinoma | Pancreatic Ductal Adenocarcinoma | Gastrointestinal Cancers

United States
Washington University School of Medicine
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Completed

To Define the Role of GLP-1 for Improving Glucose Homeostasis in Humans Following Gastric Bypass Surgery

Roux-en-Y Gastric Bypass | Bariatric Surgery | Vertical Sleeve Gastrectomy | Gastric Banding | Bypass, Gastric

United States
Fujian Medical University
Fujian Medical University Union Hospital

Completed

A Novel Online Calculator to Predict Long-term Survival and Recurrence Risk of Patients With Gastric Adenocarcinoma

Gastric Cancer

China
Sun Yat-sen University

Recruiting

Neoadjuvant Immunotherapy Plus Chemotherapy in Borrmann Type 4 and Large Type 3 Gastric Cancer (Neo-ICEBOAT)

Stomach Neoplasms | Gastric Cancer | Linitis Plastica of Stomach

China
Tianjin Medical University Cancer Institute and...

Recruiting

Continuation of Serplulimab Plus Chemotherapy After First Progression in Advanced Gastric or Gastro-oesophageal Junction Adenocarcinoma: an Open-label, Randomised Phase II Trial

Gastric Cancer (GC) Gastroesophageal Junction Cancer (GEJ)

China
Fujian Medical University

Completed

A Recurrence Nomogram for Hepatoid Adenocarcinoma of the Stomach

Gastric Cancer

China
Changhai Hospital
Peking Union Medical College Hospital; Chinese PLA General Hospital; RenJi Hospital and other collaborators

Completed

Magnetic-controlled Capsule Endoscopy vs. Gastroscopy for Detection of Gastric Diseases (MCE)

Chronic Gastritis | Gastric Diseases, | Gastric Ulcer, | Gastric Polyps, | Early Gastric Cancer,

China
Greg O'Grady

Active, not recruiting

Non-invasive Measurement of Gastric Motility

Adults,Gastric Symptoms,Suspected Gastric Motility Disorders

New Zealand
Groupe Hospitalier Paris Saint Joseph

Withdrawn

Retrospective Analysis of the Expression of the Neurotensin Receptor by Metastatic Lung Adenocarcinomas (NTS)

Metastatic Lung Adenocarcinomas
RemeGen Co., Ltd.

Recruiting

Perioperative Disitamab Vedotin Plus Toripalimab and XELOX in Gastric or Gastroesophageal Junction Adenocarcinoma.

Gastric Cancer | Gastroesophageal Junction Adenocarcinoma

China

Clinical Trials on Gastric Cardia Adenocarcinoma

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