Clinical Trials on GastroEsophageal Cancer

Total 52221 results

Imugene Limited

Active, not recruiting

A Study of IMU-131 (HER-Vaxx) in Combination With Chemotherapy or Pembrolizumab in Patients With Metastatic HER2/Neu Over-Expressing Gastric Cancer (nextHERIZON) (nextHERIZON)

Stomach Cancer | Gastric Cancer | Gastric Adenocarcinoma | Gastroesophageal Junction Adenocarcinoma | Cancer of Stomach | Stomach Adenocarcinoma

Taiwan, Australia
National Cancer Institute (NCI)

Completed

Sorafenib, Docetaxel, and Cisplatin in Treating Patients With Metastatic or Advanced Gastric or Gastroesophageal Junction Cancer

Metastatic Gastric Cancer | Adenocarcinoma of the Gastroesophageal Junction | Advanced Unresectable Gastric Cancer

United States
Shanghai Cancer Hospital, China
Fudan University; Ruijin Hospital; Xinhua Hospital, Shanghai Jiao Tong University... and other collaborators

Recruiting

PREACT Study: Locally Advanced Gastric Cancer, Chemoradiotherapy vs. Chemotherapy Followed by D2 Surgery and Adjuvant Chemotherapy (PREACT)

Adenocarcinoma | Chemoradiation | GastroEsophageal Cancer | Stomach Neoplasm | Locally Advanced Cancer

China
Academisch Medisch Centrum - Universiteit van Amsterdam...
UMC Utrecht

Active, not recruiting

The Effect of exeRcise And Diet on Quality of Life in Patients With Incurable Cancer of Esophagus and Stomach (RADICES) (RADICES)

GastroEsophageal Cancer | Incurable Disease

Netherlands
Merck Sharp & Dohme LLC

Active, not recruiting

Safety and Pharmacokinetics of Tucatinib (MK-7119) in Chinese Participants With Cancer (MK-7119-002)

Breast Neoplasms | Colorectal Cancer | Metastatic HER2+ Advanced Breast Cancer | Gastric or Gastroesophageal Junction Adenocarcinoma (GEC)

China
Vanderbilt University Medical Center

Completed

Assessment of Esophageal Epithelium Integrity With Mucosal Impedance

Gastroesophageal Reflux Disease (GERD) | Non-erosive Reflux Disease (NERD)

United States
Takeda

Completed

Safety and Quality of Life Study of Dexlansoprazole Modified Release Formulation to Treat Heartburn

Gastroesophageal Reflux Disease

United States
Phillip Brian Smith
The Emmes Company, LLC

Completed

PK Study With Pantoprazole in Obese Children and Adolescents (PAN01)

Gastroesophageal Reflux Disease

United States
AstraZeneca

Completed

Esomeprazole for Treatment of GERD in Pediatric Patients

Gastroesophageal Reflux Disease (GERD) | Erosive Esophagitis | Non-erosive Esophagitis

United States, France, Italy, Belgium
Midwest Biomedical Research Foundation
Kansas City Veteran Affairs Medical Center

Suspended

Narrow Band Imaging Project on Barrett's Esophagus

Gastroesophageal Reflux Disease | Barrett's Esophagus

Netherlands, United States, Germany
Mahidol University

Completed

Efficacy of Imipramine for Treatment of Patients With Esophageal Hypersensitivity/ Functional Heartburn

Gastroesophageal Reflux Disease

Thailand
Bristol-Myers Squibb

Withdrawn

An Investigational Immuno-therapy Study of Relatlimab Plus Nivolumab Compared to Various Standard-of-Care Therapies in Previously Treated Participants With Recurrent, Advanced or Metastatic Gastric Cancer or Gastroesophageal Junction Adenocarcinoma

Stomach Cancer | Gastric Cancer | Cancer of the Stomach | Gastroesophageal Junction

Brazil, Italy, United States, Argentina, Chile, Germany, Spain, Australia, Canada, Portugal, Mexico, Romania, Colombia, Puerto Rico
BeiGene

Completed

A Study to Investigate Sitravatinib as Monotherapy and in Combination With Tislelizumab in Participants With Unresectable Locally Advanced or Metastatic Hepatocellular Carcinoma (HCC) or Gastric/Gastroesophageal Junction Cancer (GC/GEJC)

Carcinoma, Hepatocellular | Gastric/Gastroesophageal Junction Cancer

China
Federal State Budgetary Scientific Institution...

Recruiting

Real-life Study of Changes of Gastroesophageal Reflux Disease Manifestations Due to Behavioural and Diet Adherence

Gastroesophageal Reflux Disease | GERD | Non-erosive Reflux Disease | Erosive Esophagitis | Non-Erosive Gastro-Esophageal Reflux Disease | Gastroesophageal Erosion

Russian Federation
Assistance Publique Hopitaux De Marseille

Recruiting

Anti-Reflux Mucosectomy in the Treatment of Refractory Gastro-esophageal Reflux (MARRGO)

Gastroesophageal Reflux Disease With Ulceration

France
HK inno.N Corporation

Recruiting

A Study to Evaluate the Efficacy and Safety of Tegoprazan in GERD Patients With Nighttime Heartburn

Gastroesophageal Reflux Disease

Korea, Republic of
Niguarda Hospital

Not yet recruiting

Reflux Disease After Gastric Bypass Versus Sleeve Gastrectomy in Morbid Obese Patients: an Italian Study (ReBvSS)

Obesity | Gastroesophageal Reflux Disease
NYU Langone Health
National Institute for Occupational Safety and Health (NIOSH/CDC)

Enrolling by invitation

Biomarkers of Airway Disease, Barrett's and Underdiagnosed Reflux Noninvasively (BADBURN)

Gastroesophageal Reflux Disease | Barrett Esophagus | Airway Disease

United States
Medtronic - MITG

Completed

PillCam® ESO 2 in Esophageal Pathologies (MA-76)

Gastroesophageal Reflux Disease | Barrett's Esophagus

United States
Matthias Paireder
Medtronic - MITG

Unknown

Radiofrequency Ablation in Patients With Barrett's Esophagus (RABE)

Gastroesophageal Reflux Disease | Barrett's Esophagus | Radiofrequency Ablation

Austria
Takeda

Completed

Efficacy and Safety of Dexlansoprazole on Heartburn Relief in Chinese Patients

Gastroesophageal Reflux Disease | Heartburn

China
University of North Carolina, Chapel Hill

Completed

Can E-cadherin Found in Tissue/Blood be Valuable in Identifying & Monitoring Patients With Post-proton Pump Inhibitor (PPI)-Responsive Heartburn

Gastroesophageal Reflux Disease | Heartburn

United States
AstraZeneca

Completed

Study to Compare Different Formulations of AZD3355

Gastroesophageal Reflux Disease

Sweden
University of Colorado, Denver

Recruiting

The Effect of PPI Therapy on Weight, Gut Microbiome, and Expression of GPR41 and GPR43

Obesity | Gastroesophageal Reflux Disease

United States
Reckitt Benckiser Healthcare (UK) Limited

Completed

Compound Sodium Alginate Double Action Chewable Tablet Symptomatic Relief Study

Dyspepsia | Gastroesophageal Reflux Disease

China
AstraZeneca

Completed

Study Comparing Esomeprazole Magnesium 40mg Once Daily Versus Lansoprazole 30 mg Twice Daily in Symptom Control of Subjects With Persistent Gastrooesophageal Reflux Disease (GERD)

Gastroesophageal Reflux Disease | Heartburn
Wuerzburg University Hospital

Recruiting

Hill-grade Knowledge Via Integrated Neural-network for Gastroscopy (HillKING)

Gastroesophageal Hernia

Germany
AstraZeneca

Completed

Investigate the Effect of Different Doses of Lesogaberan (AZD3355) as add-on to PPI in GERD Patients With Partial Response to PPI

Gastroesophageal Reflux Disease | Heartburn | Regurgitation

United States
Shen Lin
RemeGen Co., Ltd.

Not yet recruiting

Real-world Study of HER2-overexpressed Advanced Solid Tumors After Progression of First-line Standard Therapy

Advanced Solid Tumor | Advanced Gastric Cancer | Advanced Gastroesophageal Junction Adenocarcinoma | HER2

China
University of Pittsburgh
National Cancer Institute (NCI); National Institutes of Health (NIH)

Recruiting

Esophageal Cancer Risk Registry

Esophageal Cancer | Esophageal Diseases | Hiatal Hernia | Esophageal Achalasia | Gastroesophageal Reflux Disease (GERD)

United States
VA Office of Research and Development

Completed

Dietary Carbohydrate and GERD in Veterans (DietGERD)

Obesity | Gastroesophageal Reflux Disease

United States
University of North Carolina, Chapel Hill

Completed

Do Acid Sensing Ion Channels Contribute to Heartburn?

Gastroesophageal Reflux Disease | Heartburn

United States
Chang Gung Memorial Hospital

Completed

Efficacy and Safety of Sodium Alginate Oral Suspension to Treat Non-erosive Gastro-esophageal Reflux Disease

Gastroesophageal Reflux Disease | Heartburn

Taiwan
BioInvent International AB

Active, not recruiting

BI-1607 in Combination With Trastuzumab in Subjects With HER2-positive Advanced Solid Tumors (CONTRAST)

HER2-positive Breast Cancer | HER2-positive Gastric Cancer | Metastatic Gastric Adenocarcinoma | Metastatic Gastroesophageal Junction Adenocarcinoma | HER2-positive Metastatic Breast Cancer

Spain, United Kingdom, Germany
Fox Chase Cancer Center
AstraZeneca

Completed

A Trial of ZD6474, Paclitaxel, Carboplatin, 5-Fluorouracil, and Radiation Therapy Followed by Surgery

Cancer of the Esophagus | Adenocarcinoma of the Gastroesophageal Junction | Cancer of the Stomach

United States
Mayo Clinic
American College of Gastroenterology

Completed

Epidemiology of Barrett's Esophagus: A Population Based Study

Barrett's Esophagus | Gastroesophageal Reflux Disease (GERD) | Olmsted County Resident

United States
Universidade de Passo Fundo
Conselho Nacional de Desenvolvimento Científico e Tecnológico

Completed

Effect of Nortriptyline in Cortical Representation of Heartburn in Nonerosive Reflux Disease (NERD) Patients (NORGERD)

Gastroesophageal Reflux Disease

Brazil
FutureGen Biopharmaceutical (Beijing) Co., Ltd

Recruiting

M108 Plus CAPOX Versus Placebo Plus CAPOX as First-line Treatment for Claudin (CLDN) 18.2-Positive, HER2-Negative, PD-L1 CPS<5, Locally Advanced Unresectable or Metastatic Gastric or Gastroesophageal Junction (GEJ) Adenocarcinoma.

Locally Advanced Unresectable or Metastatic Gastric Cancer | Locally Advanced Unresectable or Metastatic Gastroesophageal Junction (GEJ) Adenocarcinoma

China
University of Southern California
National Cancer Institute (NCI); Ipsen

Withdrawn

MM-398 and Ramucirumab in Treating Patients With Gastric Cancer or Gastroesophageal Junction Adenocarcinoma

Gastric Adenocarcinoma | Metastatic Gastroesophageal Junction Adenocarcinoma | Unresectable Gastroesophageal Junction Adenocarcinoma | Gastroesophageal Junction Adenocarcinoma | Locally Advanced Unresectable Gastric Adenocarcinoma | Metastatic Unresectable Gastric Adenocarcinoma

United States
Beth Israel Deaconess Medical Center

Completed

Response to Supplement and Placebo in GERD

Dyspepsia | Heartburn | Gastroesophageal Reflux Disease (GERD)

United States
AstraZeneca

Completed

S-CEI of Nexium in Paediatric Patients

Peptic Ulcer, Gastroesophageal Reflux

Japan
Sichuan University

Unknown

Conversion Therapy With Sintilimab Plus CAPOX in Patients With Unresectable Locally Advanced or Limited Metastatic Adenocarcinoma of the Stomach or Esophagogastric Junction (CTSCAPOXSEA)

Metastatic Gastric Cancer | Gastroesophageal Junction Adenocarcinoma | Stomach Adenocarcinoma | Locally Advanced Unresectable Gastric Adenocarcinoma

China
Shanghai Zhongshan Hospital

Unknown

Early Diagnosis of Oxaliplatin-induced Portal Hypertension

Colorectal Cancer | Gastroesophageal Varices | Received Oxaliplatin-based Chemotherapy

China
China Medical University Hospital

Unknown

Effective Mechanisms of Wu-Chu-Yu Tang on Gastroesophageal Disorder

Gastroesophageal Reflux Disorder | Wu-Chu-Yu Tang | 24 Hours Esophageal PH and Multichannel Intraluminal Impedance Testing

Taiwan
Takeda

Completed

Safety and Efficacy of Dexlansoprazole Delayed-Release Capsules for Healing of Erosive Esophagitis and Maintenance of Healed Erosive Esophagitis and Relief of Heartburn in Adolescents

Gastroesophageal Reflux Disease | Erosive Esophagitis

United States, Poland, Belgium, Portugal, Italy, Hungary, Mexico, Brazil
Takeda

Completed

Sensory Evaluation of Dexlansoprazole Delayed-Release Orally Disintegrating Tablets

Gastroesophageal Reflux Disease | Heartburn | Erosive Esophagitis

United States
Mayo Clinic
National Cancer Institute (NCI)

Recruiting

Preoperative Hypofractionated Radiotherapy With FOLFOX for Esophageal or Gastroesophageal Junction Adenocarcinoma (PHOX)

Clinical Stage III Gastroesophageal Junction Adenocarcinoma AJCC v8 | Clinical Stage I Esophageal Adenocarcinoma AJCC v8 | Clinical Stage II Esophageal Adenocarcinoma AJCC v8 | Clinical Stage III Esophageal Adenocarcinoma AJCC v8 | Clinical Stage II Gastroesophageal Junction Adenocarcinoma... and other conditions

United States
National Cancer Institute (NCI)

Suspended

Nivolumab and Ipilimumab in Treating Patients With Esophageal and Gastroesophageal Junction Adenocarcinoma Undergoing Surgery

Esophageal Adenocarcinoma | Clinical Stage III Gastroesophageal Junction Adenocarcinoma AJCC v8 | Gastroesophageal Junction Adenocarcinoma | Clinical Stage II Esophageal Adenocarcinoma AJCC v8 | Clinical Stage III Esophageal Adenocarcinoma AJCC v8 | Clinical Stage IVA Esophageal Adenocarcinoma... and other conditions

United States
National Cancer Institute (NCI)

Completed

Combination Chemotherapy With or Without Vismodegib in Treating Patients With Advanced Stomach Cancer or Gastroesophageal Junction Cancer

Adenocarcinoma of the Gastroesophageal Junction | Stage IV Gastric Cancer | Recurrent Gastric Cancer | Adenocarcinoma of the Stomach | Stage IIIA Gastric Cancer | Stage IIIB Gastric Cancer | Stage IIIC Gastric Cancer

United States
University of Nebraska
National Cancer Institute (NCI)

Terminated

Panitumumab, Combination Chemotherapy, & Radiation Therapy in Esophageal or Gastroesophageal Junction Cancer

Esophageal Adenocarcinoma | Adenocarcinoma of the Gastroesophageal Junction | Stage IIB Esophageal Cancer | Stage IIA Esophageal Cancer

United States

Clinical Trials on GastroEsophageal Cancer

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