Clinical Trials on Gastroesophageal Reflux

Total 1805 results

Elevar Therapeutics

Terminated

A Study to Evaluate Safety, Tolerability, and Efficacy Profile of Rivoceranib With Paclitaxel in Advanced Gastric or Gastroesophageal Junction Cancer

Gastric Cancer | Gastroesophageal Junction Adenocarcinoma

Korea, Republic of
Medical University of Lublin

Unknown

Efficacy and Safety Study of the Combined Modality Therapy in Adenocarcinoma of the Esophago-gastric Junction

Adenocarcinoma of the Gastroesophageal Junction

Poland
Vanderbilt University Medical Center

Completed

Biology in Patients With Reflux Esophagitis (BENCH)

GERD

United States
The Affiliated Nanjing Drum Tower Hospital of Nanjing...

Recruiting

Tislelizumab in Combination With Pre-operative CRT Versus SOC for Locally Advanced G/GEJ Adenocarcinoma

Gastric Cancer | Gastroesophageal-junction Cancer

China
Sun Yat-sen University

Completed

Study of Porcine Fibrin Sealant in Preventing Cervical Anastomotic Leakage for Esophageal or Junctional Carcinoma. (PLACE020)

Esophageal Cancer | Anastomotic Leak | Gastroesophageal Junction Cancer

China
Vanderbilt University

Completed

Cough Monitoring Study

Cough | Reflux

United States
Hull University Teaching Hospitals NHS Trust

Completed

No Reflow Phenomenon Incidence and Predictors (NORM-PPCI)

STEMI | No Reflow Phenomenon

United Kingdom
Milton S. Hershey Medical Center

Recruiting

Autonomic Control of the Circulation and VDR (VDR)

Blood Pressure | Venous Distension Reflex

United States
TC Erciyes University

Completed

Intranasal Dexmedetomidine vs Midazolam-ketamine Combination for Premedication of Pediatric Patients

Oculocardiac Reflex | Premedication

Turkey
National Cancer Institute (NCI)

Recruiting

Immunotherapy Combination: Irradiated PD-L1 CAR-NK Cells Plus Pembrolizumab Plus N-803 for Subjects With Recurrent/Metastatic Gastric or Head and Neck Cancer

Gastroesophageal Junction (GEJ) Cancers | Advanced HNSCC

United States
Celularity Incorporated

Active, not recruiting

CYNK-101 in Combination With Trastuzumab and Pembrolizumab in Patients With Locally Advanced Unresectable or Metastatic HER2-Positive Gastric or Gastroesophageal Junction (G/GEJ) Adenocarcinoma

Metastatic HER2 Positive Gastroesophageal Junction Cancer

United States
Yvonne Romero
Bausch Health Americas, Inc.

Completed

Impact of Timing on the Efficacy of Zegerid 40 mg in Healing Reflux Esophagitis: A Pilot Study

Erosive Esophagitis

United States
CSPC ZhongQi Pharmaceutical Technology Co., Ltd.

Recruiting

A Study of Docetaxel for Injection (Albumin-bound) in Patients With Gastric Cancer

Gastric Adenocarcinoma | Adenocarcinoma of Gastroesophageal Junction

China
ImmVirx Pty Ltd

Recruiting

Study of Intratumoral IVX037 in Patients With Advanced or Metastatic Solid Tumours

Colorectal Cancer | Ovarian Cancer | Gastroesophageal Cancer

Australia
Asan Medical Center

Recruiting

A Study of Trastuzumab in Combination With Capecitabine and Cisplatin in Patients With Tissue HER2- But Serum HER2+ AGC

Gastric or Gastroesophageal Junction(GEJ) Adenocarcinoma

Korea, Republic of
Shanghai Zhongshan Hospital
Eastern Hepatobiliary Surgery Hospital; Xinhua Hospital, Shanghai Jiao Tong... and other collaborators

Unknown

The Effect of Hepatic Vein Pressure Gradient(HVPG)-Guided Therapy in Cirrhotic Patients With Esophagogastric Varices

Cirrhosis | Gastroesophageal Varices

China
Jiangsu HengRui Medicine Co., Ltd.

Recruiting

SHR-A1811 for Subjects With Her2-positive Gastric Cancer and Gastroesophageal Junction Adenocarcinoma After Progression on or After First-line Anti-HER2 Therapy-containing Regimen

HER2-positive Advanced Gastric Cancer or Gastroesophageal Junction Adenocarcinoma

China
Chong Kun Dang Pharmaceutical

Completed

The Study to Evaluate Efficacy and Safety of Newrabell® Tab.(Rabeprazole Sodium) 10mg b.i.d in Refractory GERD

Reflux Esophagitis

Korea, Republic of
Takeda

Completed

Efficacy and Safety of Dexlansoprazole MR and Lansoprazole on Healing of Erosive Esophagitis

Esophagitis, Peptic | Esophagitis, Reflux

United States, Poland, Bulgaria, India, Canada, Peru, Russian Federation, Australia, New Zealand, Czech Republic, Slovakia, South Africa, Latvia, Lithuania, Colombia, Germany
Takeda

Completed

Efficacy and Safety of Dexlansoprazole MR on Maintaining Healing in Subjects With Healed Erosive Esophagitis

Esophagitis, Peptic | Esophagitis, Reflux

United States
Takeda

Completed

Comparison of Dexlansoprazole MR to Placebo on the Ability to Maintain Healing in Subjects With Healed Erosive Esophagitis

Esophagitis, Peptic | Esophagitis, Reflux

United States
STEBA France

Suspended

Efficiency Study of S-Tenatoprazole-Na to Treat Erosive or Ulcerative Esophagitis

Esophagitis, Reflux

Canada
Xiyuan Hospital of China Academy of Chinese Medical...

Unknown

Study on the Rule and Mechanism of Treating Functional Gastrointestinal Diseases From the Perspective of Liver and Spleen

Non-erosive Reflux Disease/Diarrheal Irritable Bowel Syndrome

China
Rosenfeld, William E., M.D.
UCB Biopharma S.P.R.L.; PRA Health Sciences; Utrecht University; Comprehensive...

Completed

Does BRV Have Faster Onset Time & Greater Effect Than LEV in Epilepsy Pts Using PPR Pharmacodynamic Efficacy Endpoint

Photosensitive Epilepsy

United States
Idorsia Pharmaceuticals Ltd.

Completed

A Study to Evaluate the Effect of ACT-709478 in Photosensitive Epilepsy Patients

Photosensitive Epilepsy

France, Germany
Novartis Pharmaceuticals

Completed

Effect of BGG492 on EEG in Patients With Photosensitive Epilepsy

Photosensitive Epilepsy

Germany
AstraZeneca
Daiichi Sankyo Co., Ltd.

Active, not recruiting

Study of T-DXd Monotherapy in Patients With HER2-expressing Locally Advanced or Metastatic Gastric or GEJ Adenocarcinoma Who Have Received 2 or More Prior Regimens (DG-06)

Gastric or Gastroesophageal Junction (GEJ) Adenocarcinoma

China
Institut für Klinische Krebsforschung IKF GmbH...

Active, not recruiting

Modified FOLFOX Plus/Minus Nivolumab and Ipilimumab vs. FLOT Plus Nivolumab in Patients With Previously Untreated Advanced or Metastatic Gastric Cancer

GastroEsophageal Cancer | Adenocarcinoma of the Stomach

Germany
University of Utah
Elevar Therapeutics

Terminated

Apatinib With Pembrolizumab in Previously Treated Advanced Malignancies (APPEASE)

Urothelial Carcinoma | Advanced Malignancies | Gastric or Gastroesophageal Junction (GEJ) Adenocarcinoma | MSI-H or dMMR Solid Tumors

United States
Sixth Affiliated Hospital, Sun Yat-sen University

Not yet recruiting

Camrelizumab Combined With Apatinib Versus Apatinib Alone in the Third-line Treatment of Metastatic Gastric Cancer

Metastatic Gastric Adenocarcinoma | Metastatic Gastroesophageal Junction Adenocarcinoma

China
University of Colorado, Denver
National Cancer Institute (NCI)

Recruiting

Induction FLOT With CROSS CRT for Esophageal Cancer

Adenocarcinoma of the Gastroesophageal Junction | Adenocarcinoma Esophagus

United States
P. C. Thuss-Patience

Recruiting

Avelumab + Paclitaxel/ Ramucirumab (RAP) as Second Line Treatment in Gastro-esophageal Adenocarcinoma (AIO-STO-0218)

Gastroesophageal Junction Adenocarcinoma | Adenocarcinoma of the Stomach

Germany
Taiho Oncology, Inc.

Active, not recruiting

Futibatinib in Patients With Specific FGFR Aberrations

Advanced or Metastatic Solid Tumor | Advanced or Metastatic Gastric or Gastroesophageal Cancer | Myeloid or Lymphoid Neoplasms (MLN)

United States, Spain, Turkey, Hong Kong, Korea, Republic of, Belgium, Japan, Netherlands, France, Germany, Italy, Sweden, United Kingdom, Portugal, Singapore
Vall d'Hebron Institute of Oncology

Active, not recruiting

Phase II Study of Avelumab Plus Chemotherapy in the Peri-operative Treatment for Patients With Resectable Gastric Cancer (GC) or Gastroesophageal Junction Cancer (GEJC) (MONEO)

Stomach Neoplasms | Gastroesophageal Junction Adenocarcinoma

Spain
Institut für Klinische Krebsforschung IKF GmbH...

Completed

Ramucirumab Plus TAS-102 in Patients With Advanced or Metastatic Gastric Adenocarcinoma or the Gastroesophageal Junction (RE-ExPEL)

Gastric Adenocarcinoma | Metastatic Adenocarcinoma of the Gastroesophageal Junction

Germany
Weill Medical College of Cornell University
Sanofi

Completed

Phase II Study of Cabazitaxel in Refractory Metastatic Gastric or Gastroesophageal Adenocarcinoma

Gastric Adenocarcinoma | Gastroesophageal Adenocarcinoma | Distal Esophageal Adenocarcinoma

United States
UMC Utrecht
Takeda

Unknown

On-Demand Use of Pantoprazole: Determinants for Chronic Use of Acid Suppressive Medication

Peptic Ulcer | GERD | GORD | Reflux | Chronic Use of Acid Suppressive Medication
Duke University

Not yet recruiting

Biobanking Upper Gastrointestinal Tumors to Evaluate Response (BURGER With BACON)

GastroEsophageal Cancer

United States
Suzhou Transcenta Therapeutics Co., Ltd.

Not yet recruiting

Combination of TST001, Nivolumab and Chemotherapy as First-line Therapy in Advanced or Metastatic GC/GEJ Adenocarcinoma

Gastric Cancer | Advanced Cancer | Gastroesophageal-junction Cancer
Wuhan Union Hospital, China

Recruiting

Tislelizumab Combined With S-1 Plus Oxaliplatin as a Neoadjuvant Treatment in Patients With GC/GEJC

Advanced Gastric Cancer | Advanced Gastroesophageal Junction Adenocarcinoma

China
Zhou Fuxiang
Hubei Cancer Hospital; Henan Provincial People's Hospital; Huangshi Central Hospital...

Recruiting

Apatinib Plus Camrelizumab Combined With Docetaxel and S1 in First-line Treatment for Metastatic Gastric Cancer

Metastatic Gastric Adenocarcinoma | Metastatic Gastroesophageal Junction Adenocarcinoma

China
Bristol-Myers Squibb
Ono Pharmaceutical Co. Ltd

Active, not recruiting

Efficacy Study of Nivolumab Plus Ipilimumab or Nivolumab Plus Chemotherapy Against Chemotherapy in Stomach Cancer or Stomach/Esophagus Junction Cancer (CheckMate649)

Gastric Cancer | Esophageal Adenocarcinoma | Gastroesophageal Junction Cancer

United States, Argentina, Australia, Brazil, Canada, Chile, China, Colombia, Czechia, France, Germany, Greece, Hong Kong, Hungary, Israel, Italy, Japan, Korea, Republic of, Mexico, Peru, Poland, Portugal, Romania, Russian Federation, Si... and more
Yonsei University

Completed

Effects of Parental Holding on Pain Response in Young Children During Cystometry

Vesico-Ureteral Reflux | Filum Terminale Lipoma

Korea, Republic of
Vanderbilt University Medical Center
Abbott

Completed

Effect of Valproic Acid Concentration on Photic Response

Photosensitive Epilepsy

United States
Radboud University Medical Center
Stichting Bevordering Tandheelkundige Kennis of the Nederlands Tijdschrift...

Completed

7 Year Follow up Analysis on the Speed of Progression of Tooth Wear Using 3D Subtraction

Reflux Acid | Bruxism | Tooth Wear

Netherlands
Wu Jun

Not yet recruiting

Efficacy and Safety of Sintilimab Combined With Nab-paclitaxel and Tegio (aTS) as First-line Treatment of Unresectable Locally Advanced, Recurrent or Metastatic Adenocarcinoma of Gastric and Gastroesophageal Junction，a Phase II Clinical Study

Adenocarcinoma | Gastric Cancer | GastroEsophageal Cancer

China
Ruijin Hospital

Recruiting

MCCE in Assessing Efficacy of Gastro-oesophageal Varices

Gastroesophageal Varices

China
NYU Langone Health

Completed

A Phase II a Study of Lenvatinib, a Multi-targeted Tyrosine Kinase Inhibitor, Combined With Pembrolizumab (PD-1 Inhibitor) for the Treatment of Metastatic Gastroesophageal Cancer Patients Who Have Progressed on First or Subsequent Line Therapies

Gastric Cancer | GastroEsophageal Cancer

United States
Jiangsu HengRui Medicine Co., Ltd.

Completed

A Study of SHR-1210 in Combination With Capecitabine + Oxaliplatin or Apatinib in Treatment of Advanced Gastric Cancer

Gastric Cancer | GastroEsophageal Cancer

China
Jiangsu HengRui Medicine Co., Ltd.

Active, not recruiting

A Study to Evaluate SHR-1210 in Combination With Capecitabine + Oxaliplatin Sequenced by SHR-1210 + Apatinib as First-line Therapy in Treatment of Advanced Gastric Cancer

Gastric Cancer | GastroEsophageal Cancer

China

Clinical Trials on Gastroesophageal Reflux

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Drug Interventions

CROs by country

CROs in Mozambique

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