Clinical Trials on Gastrointestinal Failure in New Zealand

Total 3598 results

Southwest Oncology Group
National Cancer Institute (NCI)

Completed

S1013: Validation of Cancer Questionnaire for Skin Toxicities in Patients With Colorectal Cancer or Lung Cancer Receiving Cetuximab, Panitumumab, or Erlotinib Hydrochloride

Colorectal Cancer | Lung Cancer | Dermatologic Complications | Therapy-related Toxicity

United States
GlaxoSmithKline

Completed

Study Of Women With Severe Diarrhea-Predominant Irritable Bowel Syndrome Having Failed Conventional Therapy

Irritable Bowel Syndrome (IBS) | Irritable Colon

United States, Australia
Bausch Health Americas, Inc.

Completed

Randomized Placebo-Controlled Trial of Budesonide Multi-Matrix System (MMX®) 9 Milligrams (mg) in Participants With Ulcerative Colitis Currently on a 5-Aminosalicylic Acid (5-ASA)

Ulcerative Colitis

United States, Bulgaria, Canada, Czechia, Estonia, Hungary, Latvia, Lithuania, Poland, Russian Federation, Ukraine
Shire

Completed

A Study in Adolescents and Adults With Eosinophilic Esophagitis (EoE) Measuring Histologic Response and Determine if Reduction in Dysphagia is Achieved

Eosinophilic Esophagitis (EoE)

United States
Zealand Pharma

Recruiting

Evaluation of Long Term Safety and Efficacy of Glepaglutide in Treatment of SBS (EASE SBS 2)

Short Bowel Syndrome

United States, France, Belgium, Denmark, United Kingdom, Germany, Canada, Italy, Netherlands, Poland
Children's Hospital of Philadelphia
Eunice Kennedy Shriver National Institute of Child Health and Human Development...

Active, not recruiting

VIRTUUS Children's Study (VIRTUUS)

End Stage Renal Disease | Nephropathy | Renal Transplant Rejection | Pediatric Kidney Disease | BK Virus (Nephropathy) | Antibody-mediated Rejection | Acute Cellular Graft Rejection

United States, Canada
AstraZeneca

Completed

ASTERIX: Low Dose ASA and Nexium

Gastroesophageal Reflux

Bulgaria, Italy, South Africa, Spain, Hungary, Canada, Hong Kong, Greece, Germany, Australia, United Kingdom
Ironwood Pharmaceuticals, Inc.
Forest Laboratories

Completed

An Open-label, Long-term Safety Study of Linaclotide in Patients With Chronic Constipation or Irritable Bowel Syndrome With Constipation

Irritable Bowel Syndrome With Constipation | Chronic Constipation

United States
Eisai Inc.

Completed

Rabeprazole Extended-Release 50 mg Versus Esomeprazole 40 mg for Healing and Symptomatic Relief of Moderate to Severe Erosive Gastroesophageal Reflux Disease (GERD)

Gastroesophageal Reflux Disease (GERD)

Canada, Chile, Hungary, Bulgaria, Estonia, Latvia, United States, Croatia, Australia, India, Argentina, France, Germany
AstraZeneca

Terminated

A Study of Benralizumab in Patients With Eosinophilic Esophagitis (MESSINA)

Eosinophilic Esophagitis

United States, Italy, Spain, Canada, Poland, Germany, Japan, Netherlands, France, Israel, Russian Federation, United Kingdom
Abbott

Completed

Efficacy and Safety of Adalimumab in Subjects With Moderately to Severely Acute Ulcerative Colitis

Ulcerative Colitis

United States, Austria, Belgium, Canada, Czech Republic, Germany, Hungary, Italy, Netherlands, Poland, Puerto Rico, Slovakia, Sweden
Merck Sharp & Dohme LLC

Active, not recruiting

Study of Pembrolizumab (MK-3475) Versus Placebo in Participants With Esophageal Carcinoma Who Are Receiving Chemotherapy and Radiation Therapy (MK-3475-975/KEYNOTE-975)

Esophageal Squamous Cell Carcinoma (ESCC) | Gastroesophageal Junction Carcinoma (GEJC) | Esophageal Adenocarcinoma (EAC)

China, Canada, United States, Argentina, Belgium, Brazil, Chile, Czechia, Denmark, Estonia, France, Germany, Guatemala, Hong Kong, Hungary, Italy, Japan, Korea, Republic of, Mexico, Peru, Philippines, Portugal, Romania, Russian Federation and more
UCB Pharma

Completed

Follow-up to Welcome Study C87042 [NCT00308581] Examining Certolizumab Pegol (CDP870) in Subjects With Crohn's Disease (Welcome2)

Crohn's Disease

United States, France, Italy, United Kingdom, Belgium, Germany, Spain, Switzerland, Canada, Netherlands, Austria, Sweden
Volastra Therapeutics, Inc.

Recruiting

A Phase I/II Study of VLS-1488 in Subjects With Advanced Cancer

Gastric Adenocarcinoma | Uterine Carcinosarcoma | Triple Negative Breast Cancer | Advanced Solid Tumor | Head and Neck Squamous Cell Carcinoma | Esophageal Adenocarcinoma | Esophageal Squamous Cell Carcinoma | Transitional Cell Carcinoma of Bladder | Colorectal Adenocarcinoma | Gastroesophageal Junction... and other conditions

United States
Fate Therapeutics

Completed

FT500 as Monotherapy and in Combination With Immune Checkpoint Inhibitors in Subjects With Advanced Solid Tumors

Melanoma | Lymphoma | Renal Cell Carcinoma | Cervical Cancer | Head and Neck Cancer | Small Cell Lung Cancer | Hepatocellular Carcinoma | Gastric Cancer | Colorectal Cancer | NSCLC | Advanced Solid Tumors | HER2-positive Breast Cancer | Pancreas Cancer | Urothelial Carcinoma | Merkel Cell Carcinoma | Microsatellite Instability and other conditions

United States
Logical Therapeutics
PRA Health Sciences

Completed

Rates of Gastric Ulcer by Endoscopy in Knee Osteoarthritis Patients Receiving LT-NS001 Versus Naprosyn®

Osteoarthritis

United States
A2 Biotherapeutics Inc.
Tempus AI

Recruiting

A Study to Evaluate the Safety and Efficacy of A2B530, a Logic-gated CAR T, in Subjects With Solid Tumors That Express CEA and Have Lost HLA-A*02 Expression (EVEREST-1)

Cancer | Colorectal Neoplasms | Colorectal Cancer | Pancreatic Neoplasms | Pancreatic Cancer | NSCLC | Solid Tumor | Non Small Cell Lung Cancer | Colorectal Cancer Metastatic | Pancreas Cancer | Colorectal Adenocarcinoma | Solid Tumor, Adult | CRC | NSCLC, Recurrent | Non Small Cell Lung Cancer Recurrent | Non-Small Cell...

United States
Furiex Pharmaceuticals, Inc

Completed

Efficacy, Safety, and Tolerability of Eluxadoline in the Treatment of Participants With Diarrhea-Predominant Irritable Bowel Syndrome (IBS-d)

Irritable Bowel Syndrome

United States, Canada, Puerto Rico, United Kingdom
C. R. Bard

Recruiting

Post-market Surveillance Study of the BD® WavelinQ™ EndoAVF System (CONNECT-AV)

Arteriovenous Fistula | End-stage Renal Disease | Kidney Disease, End-Stage

United States
Lycera Corp.

Completed

An Efficacy and Safety Study of LYC-30937-EC in Subjects With Active Ulcerative Colitis

Colitis, Ulcerative

United States, Czechia, Hungary, Netherlands, Poland, Serbia, Canada
Pfizer

Completed

Pharmacokinetics/Pharmacodynamics Biomarker Study in Active Ulcerative Colitis Patients

Colitis, Ulcerative

Canada, United States, France, Netherlands, Germany, Spain, Austria, Hungary, Bulgaria, Poland, Romania
AbbVie (prior sponsor, Abbott)
North America Pediatric Renal Trials and Collaborative Studies (NAPRTCS)

Terminated

Study to Evaluate Safety of Vitamin D Receptor Activators in Patients Ages 0 to 16 With Chronic Kidney Disease Stage 5 Receiving Peritoneal Dialysis Within Current Clinical Practice

End-Stage Renal Disease | Secondary Hyperparathyroidism

United States
Janssen Research & Development, LLC

Recruiting

A Study of JNJ-77242113 in Participants With Moderately to Severely Active Ulcerative Colitis (ANTHEM-UC)

Colitis, Ulcerative

Korea, Republic of, Canada, United States, Australia, Malaysia, Germany, Turkey, Japan, Belgium, Hungary, Italy, Spain, China, Poland, United Kingdom, Brazil, France, Argentina, Czechia, Romania, India
Pfizer
Athersys, Inc

Completed

A Study To Investigate The Safety And Possible Clinical Benefit Of Multistem(r) In Patients With Moderate To Severe Ulcerative Colitis

Colitis, Ulcerative

United States, Canada, Germany, Italy, Hungary, Belgium, Slovakia, Sweden
Eli Lilly and Company
Merck Sharp & Dohme LLC; Loxo Oncology, Inc.

Recruiting

Study of LY3537982 in Cancer Patients With a Specific Genetic Mutation (KRAS G12C)

Carcinoma, Non-Small-Cell Lung | Colorectal Neoplasms | Pancreatic Neoplasms | Ovarian Neoplasms | Endometrial Neoplasms | Biliary Tract Neoplasms

Canada, United States, Japan, Australia, France, Korea, Republic of
AstraZeneca

Terminated

Placebo-Controlled Study of Brazikumab in Participants With Moderately to Severely Active Ulcerative Colitis (Expedition)

Ulcerative Colitis | IBD

United States, Italy, Taiwan, Korea, Republic of, Germany, Spain, Russian Federation, Japan, South Africa, Hungary, Poland, Israel, Puerto Rico, Czechia, Ukraine, United Kingdom, Canada, India, Slovakia
Bristol-Myers Squibb

Completed

A Study of Abatacept in Patients With Active Ulcerative Colitis

Ulcerative Colitis

United States, Australia, India, Korea, Republic of, Poland, Canada, France, Brazil, Mexico, Puerto Rico, Belgium, Switzerland, Italy, Netherlands, Germany, Ireland, South Africa, United Kingdom, Czech Republic
Shire

Completed

Safety and Efficacy Study of Teduglutide in Subjects With Short Bowel Syndrome

Short Bowel Syndrome

United States, France, Germany, Canada, Netherlands, Poland, Denmark, Belgium, United Kingdom
Ocera Therapeutics

Completed

Safety and Efficacy of AST-120 in Mild to Moderate Crohn's Patients With Fistulas

Intestinal Fistula | Inflammatory Bowel Disease

United States, Israel, Canada, United Kingdom, Germany, Belgium, Hungary, France, Austria, Czech Republic, Netherlands, Poland
Takeda

Recruiting

A Study of Vedolizumab With Tofacitinib in Adults With Ulcerative Colitis (UC)

Ulcerative Colitis

United States, Canada
Sanofi

Terminated

Efficacy and Safety of SAR339658 in Patients With Moderate to Severe Ulcerative Colitis (FUSCIA)

Ulcerative Colitis

United States, Austria, Canada, France, Germany, Italy, Poland
PDL BioPharma, Inc.

Terminated

An Observational Follow-up Study for Subjects Receiving Salvage Therapy After Previous Treatment in a Visilizumab Study for Intravenous Steroid-Refractory Ulcerative Colitis

Ulcerative Colitis

Belgium, France, United States, Italy, Australia, Czech Republic, Netherlands, Ireland, Norway, Canada, Austria, Germany, Hungary, Ukraine
Galapagos NV
Gilead Sciences

Active, not recruiting

Filgotinib in Long-Term Extension Study of Adults With Ulcerative Colitis (SELECTIONLTE)

Ulcerative Colitis

United States, Netherlands, Israel, Spain, Taiwan, Australia, Italy, Hong Kong, Singapore, Korea, Republic of, Canada, Germany, United Kingdom, New Zealand, Ireland, Poland, Romania, Croatia, Belgium, Japan, India, Malaysia, Sweden, F... and more
University of Washington, the Collaborative Health...
Cystic Fibrosis Foundation

Recruiting

Colorectal Cancer Screening in Cystic Fibrosis (NICE-CF)

Colorectal Cancer | Adenoma | Cystic Fibrosis

United States
Celgene

Active, not recruiting

A Study to Evaluate the Efficacy and Safety of CC-93538 in Adult and Adolescent Participants With Eosinophilic Esophagitis

Eosinophilic Esophagitis

Australia, United States, Argentina, Austria, Belgium, Canada, Germany, Israel, Italy, Japan, Poland, Portugal, Spain, Switzerland, United Kingdom
Chimerix

Terminated

Dociparstat for the Treatment of Severe COVID-19 in Adults at High Risk of Respiratory Failure

Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) | Acute Lung Injury | Coronavirus Disease 2019 (COVID-19)

United States
GlaxoSmithKline

Terminated

Safety, Tolerability, Efficacy and Dose-response of GSK2831781 in Ulcerative Colitis

Colitis, Ulcerative

United States, Netherlands, Ukraine, Estonia, Poland, France, Japan, Russian Federation, Slovakia, South Africa, United Kingdom, India, Bulgaria, Czechia, Serbia
Shire

Completed

Ability to Maintain or Achieve Clinical and Endoscopic Remission With MMX Mesalamine Once Daily in Adults With Ulcerative Colitis

Ulcerative Colitis

United States, France, Spain, Ireland, Czechia, Poland, Colombia, Canada, Romania, India, United Kingdom, South Africa, Belgium, Germany, Hungary
RayzeBio, Inc.

Active, not recruiting

Study of RYZ101 Compared With SOC in Pts w Inoperable SSTR+ Well-differentiated GEP-NET That Has Progressed Following 177Lu-SSA Therapy (ACTION-1)

Neuroendocrine Tumors | Carcinoid Tumor | Gastroenteropancreatic Neuroendocrine Tumor | Carcinoid | GEP-NET | Gastroenteropancreatic Neuroendocrine Tumor Disease | Pancreatic NET

Canada, Spain, United States, Netherlands, Belgium, France, Brazil
Denver Health and Hospital Authority
University of Colorado, Denver; University of Miami; Beth Israel Deaconess Medical... and other collaborators

Completed

Fibrinolytic Therapy to Treat ARDS in the Setting of COVID-19 Infection

Severe Acute Respiratory Syndrome | Respiratory Failure | Acute Respiratory Distress Syndrome

United States
Shire

Completed

Selective 5-HT4 Receptor Agonist and Proton Pump Inhibitor (PPI) in Subjects With Gastroesophageal Reflux Disease (GERD)

Gastroesophageal Reflux Disease

United States, Czechia, Germany, Latvia, Poland, Romania
National Cancer Institute (NCI)
NRG Oncology

Completed

Radiation Therapy, Paclitaxel, and Carboplatin With or Without Trastuzumab in Treating Patients With Esophageal Cancer

Esophageal Adenocarcinoma | Gastroesophageal Junction Adenocarcinoma | Stage IIA Esophageal Cancer AJCC v7 | Stage IIB Esophageal Cancer AJCC v7 | Stage IIIA Esophageal Cancer AJCC v7 | Stage IIIB Esophageal Cancer AJCC v7 | Stage IB Esophageal Cancer AJCC v7

United States
Abivax S.A.

Recruiting

ABTECT-1 - ABX464 Treatment Evaluation for Ulcerative Colitis Therapy -1

Ulcerative Colitis

Belgium, United States, Korea, Republic of, Australia, Austria, Italy, Netherlands, Spain, United Kingdom, China, France, Greece, Germany, Switzerland, Canada, India, Turkey, Portugal, Poland, Hungary, Bulgaria, Argentina, Czechia
AbbVie

Recruiting

Study to Explore the Therapeutic Effect of Eluxadoline in Treating Irritable Bowel Syndrome With Diarrhea in Children

Irritable Bowel Syndrome

United States, Poland, United Kingdom, Hungary, Bulgaria, Canada, Netherlands
AbbVie
Ironwood Pharmaceuticals, Inc.

Completed

Linaclotide Safety and Efficacy in Pediatric Participants, 6 to 17 Years of Age, With Irritable Bowel Syndrome With Constipation (IBS-C) or Functional Constipation (FC) (LINZESS)

Irritable Bowel Syndrome With Constipation | Functional Constipation

United States, Belgium, Bulgaria, Canada, Estonia, Israel, Italy, Netherlands, Poland, Puerto Rico, Spain, Ukraine, United Kingdom, Germany
Pfizer

Recruiting

A Study of PF-07820435 as a Single Agent and in Combination in Participants With Advanced Solid Tumors

Melanoma | Neoplasms | Renal Cell Carcinoma | Non-small-cell Lung Cancer | Squamous Cell Carcinoma of the Head and Neck | Urothelial Carcinoma | Colorectal Carcinoma | Ovarian Carcinoma

United States, Japan, Puerto Rico
Genzyme, a Sanofi Company

Completed

Study of Safety and Efficacy of Doxercalciferol in Patients With Chronic Kidney Disease, Stage 3 or 4, and Secondary Hyperparathyroidism

Renal Failure | Secondary Hyperparathyroidism | Chronic Renal Insufficiency

United States, Puerto Rico
New York Medical College

Completed

Human Placental-Derived Stem Cell Transplantation (HPDSC)

Mucopolysaccharidosis I | Myelodysplastic Syndrome | Acute Lymphocytic Leukemia | Acute Myelogenous Leukemia | Niemann-Pick Disease | Mucopolysaccharidosis VI | Wolman Disease | Adrenoleukodystrophy | Batten Disease | Metachromatic Leukodystrophy | Diamond-Blackfan Anemia | Severe Aplastic Anemia | Fucosidosis | Gaucher... and other conditions

United States
Allergan

Terminated

Diabetic Gastroparesis Study 05

Gastroparesis

United States, Spain, Italy, Australia, Russian Federation, Canada, India, Thailand, France, Malaysia, Denmark, Korea, Republic of, Bulgaria, Germany, Poland, Singapore, Mexico, Israel, Philippines, Ukraine, Belgium, South Africa, A... and more
Regeneron Pharmaceuticals
Sanofi

Completed

Study to Determine the Efficacy and Safety of Dupilumab in Adult and Adolescent Patients With Eosinophilic Esophagitis (EoE)

Eosinophilic Esophagitis

United States, Australia, Belgium, Canada, France, Germany, Italy, Netherlands, Spain, Sweden, Switzerland, United Kingdom

Clinical Trials on Gastrointestinal Failure in New Zealand

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Burkina Faso

Conditions

Rare Diseases

Drug Interventions

Dietary Supplements

Sponsor/Collaborators

Locations