Clinical Trials on Gastrointestinal Tolerance

Total 24572 results

Aroa Biosurgery Limited

Recruiting

Myriad™ Augmented Soft Tissue Reconstruction Registry (MASTRR)

Hidradenitis Suppurativa | Anal Fistula | Pressure Injury | Pilonidal Sinus | Necrotizing Soft Tissue Infection | Abdominal Wound Dehiscence | Lower Extremity Wound

United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Recruiting

Infliximab or Vedolizumab in Treating Immune Checkpoint Inhibitor-Related Colitis in Patients With Genitourinary Cancer or Melanoma

Malignant Solid Neoplasm | Melanoma | Colitis | Lung Non-Small Cell Carcinoma | Malignant Genitourinary System Neoplasm

United States
Lund University
Rigshospitalet, Denmark; University of Iceland; Skane University Hospital; Arba...

Enrolling by invitation

eHealth as an Aid for Facilitating and Supporting Self-management in Families With Long-term Childhood Illness (eChildHealth)

Preterm Birth | Congenital Heart Disease | Pediatric Cancer | Hirschsprung Disease | Nutrition Disorder, Child | Congenital Malformation

Denmark, Sweden
University Health Network, Toronto
University of Florida; National Institute on Deafness and Other Communication...

Completed

Physiological Flow of Liquids Used in Dysphagia Management (Neuro)

Parkinson Disease | Amyotrophic Lateral Sclerosis | Dysphagia

United States
Nanfang Hospital of Southern Medical University

Completed

Research on the Application and Mechanism of New Biological Probes in Biomedicine

Digestive System Diseases | Cardiovascular Diseases | Metabolic Diseases | Nervous System Diseases | Immune System Diseases | Endocrine System Diseases | Infectious Diseases | Tumors | Respiratory System Diseases | Urinary System Diseases | Blood Diseases

China
AbbVie

Completed

Post-marketing Observational Study to Evaluate the Incremental Impact of AbbVie's Patient Support Program on Patient Reported Outcomes and Health Resource Utilization in Inflammatory Arthritis, Psoriasis and Inflammatory Bowel Diseases in Hungary (VALUE) (VALUE)

Rheumatoid Arthritis | Psoriasis | Crohn's Disease | Ulcerative Colitis | Psoriatic Arthritis | Ankylosing Spondylitis
University Health Network, Toronto

Terminated

Trial of Best Supportive Care and Either Cisplatin or Paclitaxel to Treat Patients With Primary Ovarian Cancer, Primary Peritoneal Cancer or Fallopian Tube Cancer and Inoperable Malignant Bowel Obstruction

Ovarian Cancer | Fallopian Tube Cancer | Peritoneal Cancer | Bowel Obstruction

Canada
Danone Research

Terminated

Effect of the Consumption of a Fermented Milk on Common Infections in Adults Submitted to Multi-stressor Situation

Gastroenteritis | Sinusitis | Otitis | Bronchitis | Upper Respiratory Tract Infections | Sore Throat | Flu | Lower Respiratory Tract Infections | Rhinopharyngitis | Pneumopathy | Flu-like Syndromes

France
AstraZeneca

Completed

Nexium Capsules Helicobacter Pylori Specific Clinical Experience Investigation

Early Gastric Cancer | Gastric Ulcer | Duodenal Ulcer | Gastric Mucosa-associated Lymphoid Tissue (MALT) | Lymphoma Idiopathic Thrombocytopenic Purpura

Japan
Jonathann Kuo, MD

Active, not recruiting

Dual Sympathetic Blocks for Patients Experiencing Sympathetically-Mediated Symptoms From Long COVID (DSBLongCOVID)

SARS-CoV2 Infection | Post-COVID-19 Syndrome | Dysautonomia | Post Acute COVID-19 Syndrome | Long COVID | Long Covid19 | COVID-19 Recurrent | Post-Acute COVID-19 | Post-Acute COVID-19 Infection | Post Acute Sequelae of COVID-19 | Dysautonomia Like Disorder | Dysautonomia Orthostatic Hypotension Syndrome | Post... and other conditions

United States
University of Ulm

Recruiting

Monocyte Profiles in Critically Ill Patients With Pseudomonas Aeruginosa Sepsis (MIPSA)

Sepsis | Critically Ill | Pseudomonas Infections | Sepsis, Severe | Pseudomonas Septicemia | Pseudomonas; Pneumonia | Pseudomonal Bacteraemia | Pseudomonas Urinary Tract Infection | Pseudomonas Gastrointestinal Tract Infection

Germany
MuReva Phototherapy Inc.

Active, not recruiting

Photobiomodulation to Demonstrate Safety and Reduce the Incidence of Oral Mucositis in Adult Head & Neck Cancer Patients

Head and Neck Cancer | Oral Mucositis (Ulcerative) | Oral Mucositis (Ulcerative) Due to Radiation | Oral Mucositis (Ulcerative) Due to Antineoplastic Therapy

United States
University College, London
Versus Arthritis

Active, not recruiting

Mycophenolate in Limited Cutaneous Systemic Sclerosis (MINIMISE-Pilot) (MINIMISE)

Systemic Sclerosis | Limited Cutaneous Systemic Sclerosis

United Kingdom
Biogen

Completed

A Real-world Study of Imraldi® Use (PROPER)

Arthritis, Rheumatoid (RA) | Arthritis, Psoriatic (PsA) | Crohn's Disease (CD) | Colitis, Ulcerative (UC) | Axial Spondyloarthritis (axSpA)

Italy, United Kingdom, Germany, Belgium, Spain, Ireland
Huazhong University of Science and Technology
Qingdao University; Southern Medical University, China; Centers for Disease Control...

Unknown

Diet and Lifestyle Intervention Study in Postpartum Women in China

Constipation | Anemia | Fever | Hemorrhoids | Anal Fissure | Puerperal Infection | Breast Disease | Oral Ulcers

China
University of Cincinnati
Wyeth is now a wholly owned subsidiary of Pfizer

Completed

Study of Pantoprazole for Sleepiness Associated With Acid Reflux and Sleep Apnea

Obstructive Sleep Apnea | Acid Reflux Disease

United States
Pfizer

Completed

Azithromycin in the Treatment of Cryptosporidiosis in Patients With Acquired Immune Deficiency Syndrome (AIDS): A Randomized, Multi-Center, Placebo-Controlled, Double-Blind Study

HIV Infections | Cryptosporidiosis

United States
Tempus AI

Recruiting

Tempus Priority Study: A Pan-tumor Observational Study

Lymphoma | Leukemia | Breast Cancer | Pancreatic Cancer | Ovarian Cancer | Fallopian Tube Cancer | Lung Cancer | Prostate Cancer | Brain Cancer | Bladder Cancer | Cancer of Head and Neck | Peritoneal Cancer | Cancer of Liver | Cancer of Stomach | Cancer of Cervix | Cancer of Colon | Cancer of Rectum | Cancer of Gastrointestinal... and other conditions

United States
Rapa Therapeutics LLC

Recruiting

RAPA-201 Therapy of Solid Tumors

Breast Cancer | Head and Neck Cancer | Gastric Cancer | Solid Tumor | Bladder Cancer | Triple Negative Breast Cancer | Esophageal Adenocarcinoma | Esophageal Squamous Cell Carcinoma | Malignant Melanoma | Carcinoma of Unknown Primary | Squamous Cell Carcinoma of Larynx | Squamous Cell Carcinoma of Oral Cavity | Squamous Cell Carcinoma of Nasopharynx and other conditions

United States
GI Innovation, Inc.
Merck Sharp & Dohme LLC

Recruiting

GI-101 as a Single Agent or in Combination With Pembrolizumab, Lenvatinib or Local Radiotherapy in Advanced Solid Tumors

Melanoma | Sarcoma | Renal Cell Carcinoma | Cervical Cancer | Urinary Bladder Cancer | Vulvar Cancer | Advanced Solid Tumor | Metastatic Solid Tumor | Non-small Cell Lung Cancer | Head and Neck Squamous Cell Carcinoma | Esophageal Squamous Cell Carcinoma | Merkel Cell Carcinoma | Vaginal Cancer | Microsatellite Stable...

Korea, Republic of, United States
City of Hope Medical Center
National Cancer Institute (NCI)

Recruiting

Self-Management Survivorship Care in Stage I-III Non-small Cell Lung Cancer or Colorectal Cancer

Lung Non-Small Cell Carcinoma | Stage III Lung Cancer AJCC v8 | Stage II Lung Cancer AJCC v8 | Stage IIA Lung Cancer AJCC v8 | Stage IIB Lung Cancer AJCC v8 | Stage IIIA Lung Cancer AJCC v8 | Stage IIIB Lung Cancer AJCC v8 | Stage III Colorectal Cancer AJCC v8 | Stage IIIA Colorectal Cancer AJCC v8 | Stage... and other conditions

United States
Duke University

Recruiting

Onco-primary Care Networking to Support TEAM-based Care (ONE TEAM)

Hypertension | Diabetes Mellitus | Diabetes | Cancer | Blood Pressure | Hypercholesterolemia | Non Small Cell Lung Cancer | Cancer of Head and Neck | Cancer of Liver | Cancer, Breast | Cancer of Pancreas | Cancer Colorectal | Cancer of Prostate | Cancer of Esophagus | Cancer, Endometrial | CVD - Cardiovascular Disease | Cancer... and other conditions

United States
Fate Therapeutics

Completed

FT500 as Monotherapy and in Combination With Immune Checkpoint Inhibitors in Subjects With Advanced Solid Tumors

Melanoma | Lymphoma | Renal Cell Carcinoma | Cervical Cancer | Head and Neck Cancer | Small Cell Lung Cancer | Hepatocellular Carcinoma | Gastric Cancer | Colorectal Cancer | NSCLC | Advanced Solid Tumors | HER2-positive Breast Cancer | Pancreas Cancer | Urothelial Carcinoma | Merkel Cell Carcinoma | Microsatellite Instability and other conditions

United States
University of California, San Francisco
Bristol-Myers Squibb Foundation

Completed

Patient Portal and Navigation Program in Providing Information for Asian American Cancer Patients

Stage III Lung Cancer AJCC v8 | Stage II Lung Cancer AJCC v8 | Stage IIA Lung Cancer AJCC v8 | Stage IIB Lung Cancer AJCC v8 | Stage IIIA Lung Cancer AJCC v8 | Stage IIIB Lung Cancer AJCC v8 | Malignant Neoplasm | Stage III Colorectal Cancer AJCC v8 | Stage IIIA Colorectal Cancer AJCC v8 | Stage IIIB Colorectal... and other conditions

United States
University of Wisconsin, Madison
National Cancer Institute (NCI)

Completed

Motexafin Gadolinium and Doxorubicin in Treating Patients With Advanced Cancer

Lymphoma | Leukemia | Breast Cancer | Head and Neck Cancer | Chronic Myeloproliferative Disorders | Colorectal Cancer | Small Intestine Cancer | Lung Cancer | Prostate Cancer | Unspecified Adult Solid Tumor, Protocol Specific | Multiple Myeloma and Plasma Cell Neoplasm | Myelodysplastic/Myeloproliferative Diseases

United States
University of Arkansas

Withdrawn

Pancreatic Cancer Screening of High-Risk Individuals in Arkansas

Pancreatic Neoplasms | Colorectal Neoplasms, Hereditary Nonpolyposis | BRCA1 Gene Mutation | BRCA2 Gene Mutation | Hereditary Pancreatitis | Ataxia Telangiectasia | Peutz-Jegher's Syndrome | Familial Atypical Mole-Malignant Melanoma Syndrome

United States
Merrimack Pharmaceuticals

Unknown

A Study Evaluating MM-310 in Patients With Solid Tumors

Soft Tissue Sarcoma | Small Cell Lung Cancer | Ovarian Cancer | Squamous Cell Carcinoma of the Head and Neck | Triple Negative Breast Cancer | Non-small Cell Lung Cancer | Gastric Carcinoma | Solid Tumors | Pancreatic Ductal Adenocarcinoma | Endometrial Carcinoma | Urothelial Carcinoma | Prostate Adenocarcinoma

United States
Cancer Research UK
Royal Marsden NHS Foundation Trust; Hoffmann-La Roche; University of Manchester; University of Birmingham

Recruiting

DETERMINE Trial Treatment Arm 04: Trastuzumab in Combination With Pertuzumab in Adult, Teenage/Young Adult and Paediatric Patients With Cancers With HER2 Amplification or Activating Mutations (DETERMINE)

Colorectal Neoplasms | Ovarian Neoplasms | Solid Tumor | Gallbladder Neoplasms | Prostatic Neoplasm | Pancreatic Neoplasm | Lung Neoplasm | Haematological Malignancy | Urinary Bladder Neoplasm | Skin Neoplasm | Salivary Gland Neoplasm

United Kingdom
Cancer Research UK
Royal Marsden NHS Foundation Trust; Hoffmann-La Roche; University of Manchester; University of Birmingham

Recruiting

DETERMINE Trial Treatment Arm 05: Vemurafenib in Combination With Cobimetinib in Adult Patients With BRAF Positive Cancers. (DETERMINE)

Glioma | Melanoma | Carcinoma, Non-Small-Cell Lung | Multiple Myeloma | Colorectal Neoplasms | Ovarian Neoplasms | Solid Tumor | Thyroid Cancer, Papillary | Thyroid Carcinoma, Anaplastic | Laryngeal Neoplasms | Erdheim-Chester Disease | Haematological Malignancy

United Kingdom
City of Hope Medical Center
National Cancer Institute (NCI)

Recruiting

Time-Restricted Eating Versus Nutritional Counseling for the Reduction of Radiation or Chemoradiation Tx Side Effects in Patients With Prostate, Cervical, or Rectal Cancers

Malignant Solid Neoplasm | Recurrent Prostate Carcinoma | Localized Prostate Carcinoma | Stage I Prostate Cancer AJCC v8 | Stage II Prostate Cancer AJCC v8 | Stage IIA Cervical Cancer FIGO 2018 | Stage IIB Cervical Cancer FIGO 2018 | Stage IIIA Cervical Cancer FIGO 2018 | Stage IIIB Cervical Cancer... and other conditions

United States
Pfizer

Not yet recruiting

A Post-marketing Surveillance to Assess the Safety and Effectiveness of Zirabev in Domestic Patients With Various Cancer

Cervical Cancer | Metastatic Colorectal Cancer | Fallopian Tube Cancer | Metastatic Breast Cancer | Epithelial Ovarian Cancer | Non-small Cell Lung Cancer | Primary Peritoneal Cancer | Metastatic Kidney Cancer
OHSU Knight Cancer Institute
National Cancer Institute (NCI); Oregon Health and Science University

Recruiting

Identifying and Caring for Individuals With Inherited Cancer Syndrome

Malignant Solid Neoplasm | Lynch Syndrome | Hematopoietic and Lymphoid System Neoplasm | Breast Ductal Carcinoma In Situ | Hereditary Neoplastic Syndrome | BRCA1/2-Associated Hereditary Breast and Ovarian Cancer Syndrome

United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Recruiting

Microwave Ablation or Wedge Resection for the Treatment of Lung, Sarcoma and Colorectal Lesions, ALLUME Study

Stage IVA Lung Cancer AJCC v8 | Stage IVB Lung Cancer AJCC v8 | Lung Non-Small Cell Carcinoma | Stage III Lung Cancer AJCC v8 | Stage IV Lung Cancer AJCC v8 | Stage II Lung Cancer AJCC v8 | Stage IIA Lung Cancer AJCC v8 | Stage IIB Lung Cancer AJCC v8 | Stage IIIA Lung Cancer AJCC v8 | Stage IIIB Lung... and other conditions

United States
Quadriga Biosciences, Inc.
Novotech (Australia) Pty Limited

Completed

Dose Escalation Study to Assess the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of QBS10072S

Melanoma | Sarcoma | Kidney Cancer | Cervical Cancer | Breast Cancer | Head and Neck Cancer | Astrocytoma | Gastric Cancer | Colorectal Cancer | Pancreatic Cancer | Ovarian Cancer | Thymic Carcinoma | Lung Cancer | Prostate Cancer | Brain Cancer | Cholangiocarcinoma | Bladder Cancer | Liver Cancer | Brain Metastases | Tongue Cancer | Esophagus... and other conditions

Australia
National Cancer Institute (NCI)

Withdrawn

Nivolumab or Expectant Observation Following Ipilimumab, Nivolumab, and Surgery in Treating Patients With High Risk Localized, Locoregionally Advanced, or Recurrent Mucosal Melanoma

Cervical Carcinoma | Recurrent Melanoma | Vaginal Carcinoma | Esophageal Carcinoma | Mucosal Melanoma | Mucosal Melanoma of the Head and Neck | Oral Cavity Mucosal Melanoma | Stage II Vulvar Cancer AJCC v7 | Stage III Vulvar Cancer AJCC v7 | Stage IIIA Vulvar Cancer AJCC v7 | Stage IIIB Vulvar Cancer AJCC v7 and other conditions

United States
National Cancer Institute (NCI)

Completed

Cixutumumab, Everolimus, and Octreotide Acetate in Treating Patients With Advanced Low to Intermediate Grade Neuroendocrine Carcinoma

Lung Carcinoid Tumor | Metastatic Digestive System Neuroendocrine Tumor G1 | Paraganglioma | Pancreatic Polypeptide Tumor | Pancreatic Glucagonoma | Pancreatic Insulinoma | Recurrent Merkel Cell Carcinoma | Somatostatin-Producing Neuroendocrine Tumor | Stage IV Merkel Cell Carcinoma | Recurrent Digestive... and other conditions

United States
Odense University Hospital
Aarhus University Hospital; University of Copenhagen; University Hospital Ostrava

Recruiting

Sacral Neuromodulation for Neurogenic Lower Urinary Tract, Bowel and Sexual Dysfunction

Quality of Life | Multiple Sclerosis | Sexual Dysfunction | Bowel Dysfunction | Neurogenic Dysfunction of the Urinary Bladder | Sacral Neuromodulation

Denmark
Zhong Wang

Recruiting

Xuefu-Zhuyu Capsule for the Treatment of "Qizhi Xueyu Zheng" (Qi Stagnation and Blood Stasis Syndrome)

Endometriosis | Headache | Chronic Insomnia | Chinese Medicine | Stable Coronary Heart Disease

China
Seoul National University Hospital

Completed

Risk Factors of Meconium Obstruction and Respiratory Distress Syndrome in Preterm Infants

Respiratory Distress Syndrome in Premature Infant | Meconium Obstruction of Prematurity

Korea, Republic of
The Hospital for Sick Children

Terminated

A Physiological Study to Determine the Enteral Threonine Requirements in Infants Aged 1 to 6 Months (INFORALTHR)

Tracheoesophageal Fistula | Diaphragmatic Hernia | Surgical Infants on NG/NJ/J/G-tube Feeds | Pierre-Robin Syndrome

Canada
University of Nottingham

Completed

Monitoring of Inflammatory Conditions

Rheumatoid Arthritis | Psoriasis | Crohn Disease | Inflammatory Arthritis | Ulcerative Colitis | Psoriatic Arthritis | Reactive Arthritis | Inflammatory Disease | System; Lupus Erythematosus

United Kingdom
InnoCon Medical
Odense University Hospital; Aarhus University Hospital; Herlev Hospital

Completed

Safety and Performance of UCon for the Treatment of the Symptoms of Overactive Bladder (OAB) / Bowel Dysfunction (BD)

Urinary Incontinence | Fecal Incontinence | Urge Incontinence | Urinary Incontinence, Urge | Nocturia | Urinary Frequency More Than Once at Night | Incontinence, Nighttime Urinary | Bowel Disorders Functional

Denmark
Regeneron Pharmaceuticals

Available

Compassionate Use of Dupilumab

Bullous Pemphigoid | Pediatric Asthma | Pediatric Eosinophilic Esophagitis (EoE) | Pediatric and Adolescent Chronic Rhinosinusitis With Nasal Polyps (CRSwNP)
Seoul National University Hospital
Coloplast A/S

Enrolling by invitation

The Role of Active Administration of Peristeen Bowel Evacuation for the Management of Urinary Tract Infection

Urinary Incontinence | Neurogenic Bowel | Fecal Incontinence | Neurogenic Bladder | Spina Bifida | Fecal Impaction

Korea, Republic of
Rigshospitalet, Denmark

Active, not recruiting

Functional Outcome After Treatment for Oropharyngeal Squamous Cell Carcinoma

Quality of Life | Pain | Oropharynx Cancer | Human Papilloma Virus | Swallowing Disorder | Saliva Altered

Denmark
UCB Biopharma S.P.R.L.

Completed

Study to Test the Safe and Effective Use of an e-Device for the Self-injection of Certolizumab Pegol Solution by Subjects With Moderate to Severe Active Rheumatoid Arthritis, Active Ankylosing Spondylitis, Active Psoriatic Arthritis, or Moderately to Severely Active Crohn's Disease

Moderate and Severe Active Rheumatoid Arthritis | Active Psoriatic Arthritis | Active Ankylosing Spondylitis | Moderately to Severely Active Crohn's Disease

United States
NYU Langone Health

Completed

Effect of Nasal Continuous Positive Airway Pressure on The Pharyngeal Swallow in Neonates

Respiratory Aspiration | Deglutition Disorders | Respiratory Distress Syndrome In Premature Infants | Newborn, Premature
The Pelvic Floor Institute
Cystosure; Innovative Research Inc.

Unknown

Bladder Morphology Using 2 Different Catheter Designs

Urologic Diseases | Urinary Incontinence | Urinary Tract Infections | Pelvic Floor Disorders | Catheter-Related Infections | Catheter; Infection (Indwelling Catheter) | Urologic Injuries | Bladder Infection | Mucosal Inflammation | Mucosal Infection | Bladder Injury | Catheter Complications

United States
AstraZeneca
PHARMO Institute for Drug Outcome Research

Completed

Drug Utilization and Safety Events Among Children Using Esomeprazole, Other Proton Pump Inhibitors or H2-receptor Antagonists

Pneumonia | Gastroenteritis | Seizures | Failure to Thrive | Hospitalized Cases of Angioneurotic Oedema | Acute Interstitial Nephritis and Thrombocytopenia

Netherlands
The University of Texas Health Science Center,...

Completed

The Role of Anti-Reflux Surgery for Gastroesophageal Reflux Disease in Premature Infants With Bronchopulmonary Dysplasia (GERD-BPD)

Gastroesophageal Reflux Disease | Bronchopulmonary Dysplasia

United States

Clinical Trials on Gastrointestinal Tolerance

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CROs in Congo, DR of

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