Clinical Trials on Genetic Disease in China

Total 31731 results

GeneScience Pharmaceuticals Co., Ltd.

Unknown

Phase IV Clinical Study of Pegylated Somatropin (PEG Somatropin) to Treat Growth Hormone Deficiency Children

Dwarfism, Pituitary

China
Wuhan Neurophth Biotechnology Limited Company

Recruiting

Gene Therapy Clinical Trial for the Treatment Of Leber's HereDitary Optic Neuropathy (GOLD)

Leber's Hereditary Optic Neuropathy (LHON)

China
Second Affiliated Hospital, School of Medicine,...

Unknown

The Pathophysiology of Tourette Syndrome: a Multimodal Study (PTS)

Tourette Syndrome

China
Anhui Medical University

Not yet recruiting

The Efficacy of Repetitive Transcranial Magnetic Stimulation With Precision Neuronavigation in Parkinson's Disease

Parkinson Disease | Transcranial Magenetic Stimualtion | Supplementary Motor Area

China
Beijing Institute of Heart, Lung and Blood Vessel...
Beijing Anzhen Hospital; Chinese Academy of Medical Sciences, Fuwai Hospital

Unknown

An Integrative-"Omics" Study of Cardiomyopathy Patients for Diagnosis and Prognosis in China (AOCC)

Dilated Cardiomyopathy | Hypertrophic Cardiomyopathy | Arrhythmogenic Right Ventricular Cardiomyopathy | Restrictive Cardiomyopathy | Left Ventricular Non-compaction

China
Tongji Hospital

Recruiting

Efficacy and Safety of Long Term Use of hCG or hCG Plus hMG in Males With Isolated Hypogonadotropic Hypogonadism (IHH) (IHH)

Infertility | Kallmann Syndrome | Isolated Hypogonadotropic Hypogonadism

China
Boehringer Ingelheim

Recruiting

A Study to Test Whether Spesolimab Helps People With a Skin Disease Called Netherton Syndrome

Netherton Syndrome

Belgium, United Kingdom, Australia, Germany, China, Malaysia, United States, Japan, France, Israel, Bulgaria, Italy, Switzerland, Netherlands, Portugal
Nanfang Hospital, Southern Medical University

Recruiting

A Single-arm, Open-label Study of Olverembatinib, CD3/CD19 Bispecific T-cell Engager, and Chidamide in Patients With Newly Diagnosed Ph+ALL (ABC)

Acute Lymphoblastic Leukemia | Philadelphia Chromosome | Adult ALL | Philadelphia-Positive ALL | IKZF1 Gene Mutation

China
Nanfang Hospital of Southern Medical University
Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University; First People's Hospital... and other collaborators

Completed

Influence of Molecular Abnormalities on Response of VAH vs. VEN+HMA in RR-AML

Refractory Acute Myeloid Leukemia | Relapsed Acute Myeloid Leukemia | Gene Abnormality | Cytogenetic Abnormality

China
Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University

Recruiting

Rasburicase Treatment in Chronic Gouty Arthritis

Chronic Gout

China
AstraZeneca

Recruiting

Observational Study to Evaluate the Effect and Safety of Selumetinib in Pediatric Patients With NF1-PNs (PEDIA)

Neurofibroma, Plexiform

China
Keymed Biosciences Co.Ltd

Completed

Subcutaneously CM310/Placebo in Patients With Moderate-to-Severe Atopic Dermatitis (AD)

Moderate-to-severe Atopic Dermatitis

China
Beijing Institute of Heart, Lung and Blood Vessel...

Unknown

Metabolomic Study of All-age Cardiomyopathy (MAC)

Dilated Cardiomyopathy | Hypertrophic Cardiomyopathy | Arrhythmogenic Right Ventricular Cardiomyopathy | Restrictive Cardiomyopathy | Left Ventricular Non-compaction

China
Second Affiliated Hospital, School of Medicine,...

Recruiting

Role for Biochemical Assays and Kayser-Fleischer Rings in Diagnosis of Wilson Disease

Wilson Disease

China
Shanghai Minimally Invasive Surgery Center

Unknown

Detect Microsatellite Instability Status in Blood Sample of Advanced Colorectal Cancer Patients by Next-Generation Sequencing

Colorectal Neoplasms

China
Shandong University

Not yet recruiting

Cold Snare Polypectomy for Small Bowel Polyps in Patients With Peutz-Jeghers Syndrome

Peutz-Jeghers Syndrome | Small Bowel Polyp

China
GeneCradle Inc

Recruiting

Evaluation of the Safety and Efficacy of Infantile-onset Pompe Disease Gene Therapy Drug

Pompe Disease Infantile-Onset

China
The First Affiliated Hospital of Zhejiang Chinese...

Recruiting

Peripheral Mechanisms of Humoral Immune Effector-mediated Tourette's Syndrome and the Role of Tuina Intervention

Inflammatory Response | Tourette Syndrome in Children | Food Intolerance

China
Xuanwu Hospital, Beijing

Recruiting

Spinal Cord Stimulation Therapy for Hereditary Spastic Paraplegias Patients

Gait | Motor Function

China
First Affiliated Hospital of Fujian Medical University

Recruiting

PCSK9 Inhibitor Treatment for Patients With SPG5

Hereditary Spastic Paraplegia Type 5

China
Southern Medical University, China

Unknown

Efficacy of Yinzhihuang Oral Liquid on Indirect Bilirubin of Neonates With Glucose-6-phosphate Dehydrogenase Deficiency

Neonatal Hyperbilirubinemia

China
Chia Tai Tianqing Pharmaceutical Group Co., Ltd.

Not yet recruiting

A Clinical Trial to Evaluate the Tolerability and Pharmacokinetics of TQ-B3234 in Patients With Type I Neurofibromatosis

Type I Neurofibromatosis

China
Sunshine Guojian Pharmaceutical (Shanghai) Co.,...

Recruiting

A Phase Ib/II Study of Recombinant Anti-IL-1β Humanized Monoclonal Antibody Injection in Chinese Participants With Acute Gout

Acute Gout

China
Nanfang Hospital of Southern Medical University
Peking University People's Hospital; Guangzhou First People's Hospital; Sun Yat-Sen... and other collaborators

Unknown

Effect of Prophylactic TKI Therapy Post-transplants on Ph+ ALL Undergoing Allo-HSCT With MRD Positive Pre-transplants

Allogeneic Hematopoietic Stem Cell Transplantation | Minimal Residual Disease | Philadelphia Chromosome Positive Acute Lymphocytic Leukemia | Tyrosine Kinase Inhibitor

China
Bioray Laboratories
Xiangya Hospital of Central South University; First Affiliated Hospital of... and other collaborators

Enrolling by invitation

Safety and Efficacy Evaluation of BRL-101 in Subjects With Transfusion-Dependent β-Thalassemia

Beta-Thalassemia

China
Peking University
National Natural Science Foundation of China; Institute of reproductive and...

Completed

Effects of Low-dose Complex B-vitamins on Homocysteine and Framingham Risk Score Among Chinese Elderly

Hyperhomocysteinemia

China
Beijing Friendship Hospital
Peking University First Hospital; Fudan University; Beijing YouAn Hospital; Beijing... and other collaborators

Recruiting

China Registry for Genetic / Metabolic Liver Diseases

Genetic/Metabolic Liver Diseases

China
Second Affiliated Hospital, School of Medicine,...

Active, not recruiting

Surgical Treatment of Marfan Syndrome With Subluxation Lens

Marfan Syndrome | Lens Subluxation or Dislocation

China
Jiangsu Gensciences lnc.

Completed

A Study to Evaluate the Pharmacokinetics，Safety and Tolerability of PEG Recombinant Human Coagulation Factor VIII-Fc Fusion Protein for Injection

Severe Hemophilia A

China
Chia Tai Tianqing Pharmaceutical Group Co., Ltd.

Unknown

Evaluate Efficacy and Safety of Recombinant Factor VIII （rFVIII）Treatment of Severe or Moderately Severe Hemophilia A

Hemophilia A

China
Second Affiliated Hospital, School of Medicine,...

Completed

Clinical Features and Outcome of Wilson's Disease With Generalized Epilepsy in Chinese Patients

Wilson Disease | Generalized Epilepsy

China
Third Affiliated Hospital, Sun Yat-Sen University

Unknown

Plasma Exchange and Continuous Hemodiafiltration in Treatment of Wilson's Disease-related Liver Failure

Liver Failure | Wilson Disease

China
Second Affiliated Hospital, School of Medicine,...

Recruiting

Clinical Features and Outcome in Patients With Osseomuscular Type of Wilson's Disease

Clinical Features and Outcome

China
Shengjing Hospital

Not yet recruiting

Combination Therapy of Anthracyclines for Children With Nephroblastoma

0.5-14 Year Old Children With Nephroblastoma

China
Innovent Biologics (Suzhou) Co. Ltd.

Active, not recruiting

IBI310 in Combination With Sintilimab in Patients With DNA Mismatch Repair Deficient (dMMR)/Microsatellite Instability High (MSI-H) Locally-advanced or Metastatic Colorectal Cancer

Colorectal Cancer

China
Bayer

Completed

Prophylaxis Versus on Demand Treatment for Children With Hemophilia A

Hemophilia A

China
Shanghai Kechow Pharma, Inc.

Recruiting

HL-085 in Adults With Neurofibromatosis Type 1 (NF1) and Inoperable Plexiform Neurofibromas

Neurofibromatosis 1 | Plexiform Neurofibromas

China
Shanghai Jiao Tong University School of Medicine

Not yet recruiting

Comparisons of Different Forms of Glucocorticoid on the Recovery of Reproductive Function in Patients With 21α-hydroxylase Deficiency (CGP21)

Congenital Adrenal Hyperplasia

China
Bioray Laboratories
Xiangya Hospital of Central South University; Sun Yat-Sen Memorial Hospital... and other collaborators

Not yet recruiting

Long-term Follow-up Study of BRL-101 for TDT

Thalassemia, Beta

China
Huazhong University of Science and Technology
Shiyan Taihe Hospital

Active, not recruiting

A Single Intravitreal Injection of rAAV2-ND4 for the Treatment of Leber's Hereditary Optic Neuropathy

Leber Hereditary Optic Neuropathy

China
Peking Union Medical College Hospital
the Second Affiliated Hospital of South China University; The Loudi Central...

Completed

A Clinical Trial of the Effectiveness and Safety of Software Assisting Diagnose the Intestinal Polyp Digestive Endoscopy by Analysis of Colonoscopy Medical Images From Electronic Digestive Endoscopy Equipment

Artificial Intelligence | Enteroscope | Intestinal Polyposis, Adenomatous

China
Cancer Institute and Hospital, Chinese Academy...

Unknown

Treatment Protocol of Children With Philadelphia Chromosome Negative High Risk Acute Lymphoblastic Leukemia

Childhood Acute Lymphoblastic Leukemia | B-cell Childhood Acute Lymphoblastic Leukemia | Philadelphia Chromosome, Ph^1^, Absent

China
Akeso

Not yet recruiting

A Phase II Study to Evaluate the Safety and Efficacy of AK120 in Subjects With Moderate to Severe Atopic Dermatitis

Atopic Dermatitis

China
Kaifeng Pharmaceutical (Group) Co., Ltd.
Beijing Furen Biomedical Research Institute Co., Ltd.

Unknown

A Study to Evaluate the Pharmacokinetics of Recombinant Human Coagulation Factor VIII-Fc Fusion Protein for Injection

Hemophilia A

China
Hospital Affiliated to the Institute of Neurology...

Not yet recruiting

Clinical Value of DWI-ADC Matching in the Short-term Prognosis of Wilson's Disease

Hepatolenticular Degeneration; Wilson

China
Sun Yat-sen University
Guangdong Provincial Hospital of Traditional Chinese Medicine; Fujian Cancer... and other collaborators

Recruiting

PD-1 Antibody for The Prevention of Adenomatous Polyps and Second Primary Tumors in Lynch Syndrome Patients

Lynch Syndrome

China
Shanghai Pulmonary Hospital, Shanghai, China

Unknown

Chromosomal Instability as a Surrogate Biomarker of Drug Resistance in Immunotherapy for Lung Cancer Patients (CINSBDRILCP)

Lung Cancer

China
Guangdong Provincial Hospital of Traditional Chinese...

Recruiting

Immediate Analgesic Effects of Cheek Acupuncture for Acute Gouty Arthritis (CAAGA)

Acute Pain | Acupuncture | Acute Gout Arthritis

China
Xijing Hospital of Digestive Diseases

Completed

Primary Chemoprevention of Familial Adenomatous Polyposis With Berberine Hydrochloride

Colorectal Adenomas

China
Reistone Biopharma Company Limited

Active, not recruiting

Evaluate the Efficacy and Safety of Topical SHR0302 Ointment in Patients With Mild-to-Moderate Atopic Dermatitis (MARBLE-23)

Atopic Dermatitis

China

Clinical Trials on Genetic Disease in China

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