Clinical Trials on Genetic Differences of Lipid Metabolism/Healthy Subjects

Total 1617 results

Wake Forest University Health Sciences
National Center for Complementary and Integrative Health (NCCIH); Office of...

Completed

Botanical Oils Study to Determine Genetic Differences in the Way Your Body Processes Fats in Edible Oils

Genetic Differences of Lipid Metabolism/Healthy Subjects

United States
GlaxoSmithKline

Completed

Study Of Pharmacokinetics and Pharmacodynamics Effects Of GSK256073A On Healthy Volunteers

Healthy Subjects | Dyslipidaemias

United States
GlaxoSmithKline

Completed

A Second Study to Determine the Effect of GSK256073A on HVTs

Healthy Subjects | Dyslipidaemias

United States
University of Surrey
Imperial College London; University of Reading

Completed

RISSCI-1 Blood Cholesterol Response Study (RISSCI-1)

Healthy | Lipid Metabolism | Lipids

United Kingdom
Inje University

Completed

The Effect of CYP3A Genetic Polymorphism on the Pharmacokinetics of Phosphodiesterase type5 Inhibitors in Male Subjects (CYP3APDE5I)

Healthy Subjects | Pharmacokinetics of Three PDE5Is | Genetic Polymorphic CYP3A5
Norwegian University of Science and Technology

Completed

Endothelial Dysfunction Induced by Postprandial Lipemia

Healthy Subjects

Norway
GlaxoSmithKline

Completed

Study To Evaluate The Effects Of GW856553 On Endothelial Function/Vascular Compliance In Subjects With Dyslipidaemia.

Healthy Subjects | Dyslipidaemia | Dyslipidaemias

United Kingdom
GlaxoSmithKline

Completed

A Study To See If GSK256073A Can Block Niacin-Induced Flushing In Healthy Volunteers

Healthy Subjects | Dyslipidaemias

United States
Daniel Doberer

Completed

Effects of Heme Arginate in Healthy Male Subjects (HEMAHS)

Healthy Subjects | Genetic Polymorphism | Heme Oxygenase

Austria
Astellas Pharma Global Development, Inc.

Completed

A Dose Escalation Study to Assess the Safety, Tolerability, and Pharmacokinetics of ASP2408 Following Single Intravenous Doses in Healthy Subjects

Healthy Subjects | Pharmacokinetics of ASP2408

United States
Astellas Pharma Europe B.V.

Completed

Drug to Drug Interaction Study With Ipragliflozin and Furosemide

Healthy Subjects | Pharmacokinetics of Ipragliflozin

United Kingdom
Astellas Pharma Inc

Completed

A Study to Assess the Safety, Tolerability and Pharmacokinetics of ASP015K

Healthy Subjects | Pharmacokinetics of ASP015K

United States
Astellas Pharma Europe B.V.

Completed

A Study to Assess the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of ASP6294 Administered Intravenously or Subcutaneously in Healthy Young Male and Female Subjects

Healthy Subjects | Pharmacokinetics of ASP6294

United Kingdom
Astellas Pharma Europe B.V.

Terminated

A Study to Assess the Safety, Tolerability and Pharmacokinetics of ASP2205 in Healthy Young Males and Females and Elderly Females and to Evaluate the Effect of Food on the Pharmacokinetics of a Single Dose of of ASP2205

Healthy Subjects | Pharmacokinetics of ASP2205

United Kingdom
Astellas Pharma Global Development, Inc.
Basilea Pharmaceutica International Ltd

Completed

A Study to Evaluate the Effect of Multiple Doses of Esomeprazole on the Pharmacokinetics of Isavuconazole

Healthy Subjects | Pharmacokinetics of Isavuconazole

United States
Astellas Pharma Europe B.V.

Completed

Absolute Bioavailability Study With Ipragliflozin

Healthy Subjects | Bioavailability of Ipragliflozin

United Kingdom
Astellas Pharma Global Development, Inc.
Cubist Pharmaceuticals LLC

Completed

A Study to Assess the Safety, Tolerability and Pharmacokinetics of Single and Multiple Ascending Doses of Fidaxomicin in Healthy Male Japanese and Caucasian Subjects

Healthy Subjects | Pharmacokinetics of Fidaxomicin

United States
Astellas Pharma Global Development, Inc.
Janssen Biotech, Inc.

Completed

A Study to Evaluate the Effect of Verapamil on the Pharmacokinetics of ASP015K in Healthy Adult Subjects

Healthy Subjects | Pharmacokinetics of ASP015K

United States
Astellas Pharma Inc

Completed

To Compare Blood and Urine Concentrations of Mirabegron (YM178) in Healthy Poor or Extensive Metabolizers for CYP2D6 and to Assess the Effect of Mirabegron on the Metabolism of Metoprolol

Healthy Subjects | Pharmacokinetics of Mirabegron

Netherlands
Astellas Pharma Inc

Completed

To Evaluate the Effect of Mirabegron (YM178) on Blood Levels of Desipramine When They Are Taken Together

Healthy Subjects | Pharmacokinetics of Mirabegron

France
Astellas Pharma Europe B.V.

Completed

A Study to Assess the Pharmacokinetics, Metabolism and Excretion Routes of ASP3652 in Man, After Administration of 14C Radio Labeled ASP3652

Healthy Subjects | Pharmacokinetics of ASP3652

United Kingdom
Astellas Pharma Global Development, Inc.
Janssen Biotech, Inc.

Completed

Drug-Drug Interaction Study Evaluating Effects of ASP015K on Rosuvastatin

Healthy Subjects | Pharmacokinetics of ASP015K

United States
Astellas Pharma Europe B.V.
Medivation, Inc.

Completed

A Study to Explore the Routes of Elimination of MDV3100

Healthy Subjects | Pharmacokinetics of MDV3100

Netherlands
Astellas Pharma Inc

Completed

A Study to Assess the Pharmacokinetics of ASP015K in Healthy Male Subjects

Healthy Subjects | Pharmacokinetics of ASP015K

United States
Astellas Pharma Europe B.V.

Terminated

A Study to Assess the Safety and Tolerability, Including Gastrointestinal Safety, Pharmacokinetics and Pharmacodynamics of ASP7657 in Caucasian Healthy Male and Female Subjects

Healthy Subjects | Pharmacokinetics of ASP7657 | Pharmacodynamics of ASP7657

United Kingdom
Astellas Pharma Europe B.V.

Completed

A Study to Assess the Safety, Tolerability, and Effects in and on the Body of Healthy Young and Elderly Male and Female Subjects of Ascending Multiple Oral Doses of ASP3652

Healthy Subjects | Pharmacokinetics of ASP3652 | Pharmacodynamics of ASP3652

Netherlands
Astellas Pharma Europe B.V.

Completed

A Study to Investigate the Appearance and Disappearance of ASP3652 in Blood and Spinal Fluid in Healthy Male Subjects

Healthy Subjects | Pharmacokinetics of ASP3652 | Pharmacodynamics of ASP3652

United Kingdom
Astellas Pharma Global Development, Inc.
Basilea Pharmaceutica International Ltd

Completed

A Study to Evaluate the Effect of Multiple Doses of Isavuconazole on the Pharmacokinetics of a Single Dose of Sirolimus in Healthy Subjects

Healthy Subjects | Pharmacokinetics of Isavuconazole | Pharmacokinetics of Sirolimus

United States
Danone Research

Completed

Pilot Study in the Cholesterol Absorption Reduction After Consumption of Low-fat, Drinkable Fermented Milk Enriched With Plant Sterols

Mildly Hypercholesterolemic Subjects

Canada
Danone Research

Completed

Effects of Fermented Milk Product Enriched With Plant Sterols and Policosanols in Mild Hypercholesterolaemic Adults

Mildly Hypercholesterolemic Subjects

United Kingdom
Danone Research

Completed

Effect of the Consumption of a Fermented Milk Enriched With Plant Sterols (Italy)

Mildly Hypercholesterolemic Subjects

Italy
Astellas Pharma Europe B.V.
FibroGen

Completed

A Study to Evaluate the Effects of Multiple Doses of FG-4592 on the Exposure, Safety and Tolerability and Effect of Warfarin in Healthy Subjects

Healthy Subjects | Pharmacokinetics of FG-4592

Germany
Astellas Pharma Inc

Completed

A Study to Assess the Safety, Tolerability and Pharmacokinetics of ASP015K

Healthy Subjects | Pharmacodynamics | Pharmacokinetics of ASP015K

United States
Astellas Pharma Global Development, Inc.
Basilea Pharmaceutica International Ltd

Completed

A Study to Evaluate the Effect of Multiple Doses of Isavuconazole on the Pharmacokinetics of Repaglinide and Caffeine

Healthy Subjects | Pharmacokinetics of Caffeine | Pharmacokinetics of Repaglinide

United States
Astellas Pharma Global Development, Inc.
Basilea Pharmaceutica International Ltd

Completed

A Study to Evaluate the Effect of Multiple Doses of Isavuconazole on the Pharmacokinetics of Metformin

Healthy Subjects | Pharmacokinetics of Isavuconazole | Pharmacokinetics of Metformin

United States
Astellas Pharma Global Development, Inc.
Basilea Pharmaceutica International Ltd

Completed

A Study to Evaluate the Effect of Multiple Doses of Isavuconazole on the Pharmacokinetics of a Single Dose of Prednisone in Healthy Adult Subjects

Healthy Subjects | Pharmacokinetics of Isavuconazole | Pharmacokinetics of Prednisolone

United States
Yung Shin Pharm. Ind. Co., Ltd.
Taichung Veterans General Hospital

Completed

Pharmacokinetics of Two Formulation of Tenofovir Disoproxil Fumarate

Pharmacokinetic of Tenofovir in Healthy Subjects

Taiwan
Astellas Pharma Inc

Completed

A Study to Evaluate Absorption, Distribution and Elimination of Mirabegron After Oral Administration to Non-elderly Healthy Chinese Subjects

Healthy Subjects | Plasma Concentration of Mirabegron

Japan
Shandong Luoxin Pharmaceutical Group Stock Co.,...

Completed

Mass Balance and Biotransformation Study of [14C]LXI-15028 in Humans

Healthy Subjects | Pharmacokinetics of 14C-labeled of LXI-15028

China
Radboud University Medical Center
Theia Foundation, Zilveren Kruis Achmea

Terminated

Women Abuse and the Role of the Family Doctor.

Improved Recognition of Partner Abuse | Gender Differences in Discussing Partner Abuse | Abused Women's Expectations,Experiences | Abused Women's Health Care Utilisation

Netherlands
Astellas Pharma Global Development, Inc.

Completed

A Dose Escalation Study to Assess the Safety, Tolerability, and Pharmacokinetics of ASP4058 Following Single Oral Doses

Healthy Subjects | Pharmacokinetics of ASP4058 | Food Effect of ASP4058

United States
Astellas Pharma Europe B.V.

Completed

A Study to Assess the Effect of Race on How a Single Dose of ASP3652 is Taken up, Metabolized and Distributed Through the Bodies of Young, Healthy Male and Female Subjects, and Its Safety and Tolerability

Healthy Subjects | Pharmacokinetics | Pharmacodynamics | Effect of Race

United Kingdom
Astellas Pharma Inc

Completed

Pharmacokinetic Interaction Study to Assess the Effect of ASP015K on Tacrolimus in Healthy Volunteers

Healthy Subjects | Drug Interactions | Pharmacokinetics of ASP015K

United States
University of Copenhagen

Completed

Biomarkers of Meats and Potatoes Intake. (MEPO)

Biomarkers of Food Intake in Healthy Subjects
Astellas Pharma Inc

Completed

To Evaluate if Multiple Doses of Rifampicin Change the Blood Concentration of YM150 (Darexaban)

Healthy Subjects | Pharmacokinetics of Darexaban and Metabolites

France
Astellas Pharma Global Development, Inc.
Basilea Pharmaceutica International Ltd

Completed

Study to Evaluate the Pharmacokinetics of 14C-labeled Isavuconazole Following a Single Oral Dose of 14C-labeled Prodrug Isavuconazonium Sulfate (BAL8557) in Healthy Male Subjects

Healthy Subjects | Pharmacokinetics of 14C-labeled Isavuconazole

United States
Astellas Pharma Inc

Completed

Pharmacokinetic Interaction Study to Assess the Effect of ASP015K on Mycophenolate Mofetil in Healthy Volunteers

Healthy Subjects | Drug Interactions | Pharmacokinetics of ASP015K

United States
Astellas Pharma Inc

Completed

To Evaluate if Multiple Doses of Ketoconazole Change the Blood Concentration of YM150 (Darexaban)

Healthy Subjects | Pharmacokinetics of Darexaban and Metabolites

France
Astellas Pharma Global Development, Inc.
Janssen Biotech, Inc.

Completed

A Study to Assess the Relative Bioavailability Between Two ASP015K Tablets and the Food Effect of a New Tablet in Healthy Adult Subjects

Healthy Subjects | Bioavailability of ASP015K | Pharmacokinetics of ASP015K | Food Effect of ASP015K

United States
University of Oslo
Oslo University Hospital; Mills DA

Completed

Postprandial Response After Intake of Meals With Different Fatty Acid Composition

Healthy | Familial Hypercholesterolemia

Norway

Clinical Trials on Genetic Differences of Lipid Metabolism/Healthy Subjects

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