Clinical Trials on Genu Valgus

Total 1027 results

N.N. Blokhin National Medical Research Center of...

Recruiting

Osimertinib for Russian EGFR T790M Mutation-positive NSCLC Patients Who Progressed on or After EGFR TKI Therapy (TRUST)

Non Small Cell Lung Cancer | EGFR Gene Mutation | T790M

Russian Federation
Biogen

Recruiting

A Study of BIIB067 (Tofersen) Initiated in Clinically Presymptomatic Adults With a Confirmed Superoxide Dismutase 1 Mutation (ATLAS)

Amyotrophic Lateral Sclerosis Associated With a SOD1 Gene Mutation

United States, Canada, Spain, Australia, Germany, Italy, Japan, Korea, Republic of, United Kingdom, Belgium, Brazil, France, Poland, Sweden
Xcovery Holding Company, LLC

Available

Expanded Access to Ensartinib for Participants With ALK+ NSCLC

Non-Small Cell Lung Cancer | ALK Gene Rearrangement Positive

United States
Fudan University

Unknown

Almonertinib/Pemetrexed/Carboplatin in EGFR T790M+ Advanced Lung Cancer (APPEAL)

Lung Cancer, Non-small Cell | EGFR Gene Mutation | EGFR T790M

China
Merck Sharp & Dohme LLC

Completed

A Study to Assess the Safety, Tolerability, and Effects of MK-0974 (Telcagepant) on Exercise Tolerance in Patients With Stable Angina (MK-0974-014)

Angina Pectoris | Coronary Heart Disease | Calcitonin Gene-related Peptide Receptor
Medical University of Vienna

Recruiting

Vagus Stimulation in Female Long COVID Patients. (Vagus)

Vagus Nerve Diseases | Post-COVID-19 Syndrome | Long COVID | Long Covid19 | Post COVID-19 Condition | Post-COVID Syndrome | Post COVID Condition

Austria
Nanfang Hospital of Southern Medical University
Shenzhen Hospital of Southern Medical University

Unknown

Comparison of Endoscopic and Laparoscopic Resection for Small Gastric Gastrointestinal Stromal Tumor (CELSGIST)

Therapeutic Value of Endoscopic and Laparoscopic Resection for Small Gastric Gastrointestinal Stromal Tumor

China
China Medical University Hospital

Not yet recruiting

Nintedanib Plus EGFR TKI In EGFR-mutated Non-small Cell Lung Cancer Patients

Non-small Cell Lung Cancer | EGFR Gene Mutation | EGFR-TKI Resistant Mutation
University Hospital Schleswig-Holstein
Michael J. Fox Foundation for Parkinson's Research

Recruiting

Sensorimotor Integration in Monogenic Parkinson-dystonia Syndromes (SensoMo-PD)

Dystonia | Parkinson | Dystonia, Familial | DYT3 | DYT5 | PINK1 Gene Deletion

Germany
Massachusetts General Hospital
LUNGevity Foundation; Addario Lung Cancer Medical Institute

Recruiting

Immune and Genomic Markers in ALK+ NSCLC

Non-Small Cell Lung Cancer | Anaplastic Lymphoma Kinase Gene Translocation

United States
Tulane University School of Medicine
BioMarin Pharmaceutical

Completed

Evaluation of Behavior, Executive Function, Neurotransmitter Function and Genomic Expression Kuvan Nonresponders (IST)

Phenylketonuria | Behavior and Behavior Mechanisms | PAH Gene Expression

United States
Sohag University

Not yet recruiting

Thyroid Functions in Children With Congenital Heart Diseases

Value of Thyroid Functions in Children With Congenital Heart Diseases

Egypt
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Recruiting

Olaparib With Cediranib or AZD6738 for the Treatment of Advanced or Metastatic Germline BRCA Mutated Breast Cancer

Anatomic Stage III Breast Cancer AJCC v8 | Anatomic Stage IIIA Breast Cancer AJCC v8 | Anatomic Stage IIIB Breast Cancer AJCC v8 | Anatomic Stage IIIC Breast Cancer AJCC v8 | Prognostic Stage III Breast Cancer AJCC v8 | Prognostic Stage IIIA Breast Cancer AJCC v8 | Prognostic Stage IIIB Breast... and other conditions

United States
Aspira Women's Health

Terminated

Multifactorial Risk Assessment for Breast & Ovarian Cancer Risk Detection (OVA360)

Hereditary Breast and Ovarian Cancer | Adnexal Mass | Germline BRCA1 Gene Mutation | Germline BRCA2 Gene Mutation

United States
Assistance Publique - Hôpitaux de Paris
Institut National de la Santé Et de la Recherche Médicale, France; ANSES

Not yet recruiting

Impact of Environmental Exposures on Tumor Risk in Subjects at Risk of Hereditary SDHx Paraganglioma (PGL-EXPO-1)

Environmental Exposure | Genetic Predisposition | SDH Gene Mutation
BioMarin Pharmaceutical

Active, not recruiting

Gene Therapy Study in Severe Hemophilia A Patients With Antibodies Against AAV5 (GENEr8-AAV5+)

Hemophilia A | Gene Therapy | Blood Disorder | Clotting Disorders

Taiwan, Korea, Republic of, United Kingdom, South Africa
Kymera Therapeutics, Inc.

Suspended

Safety, PK/PD, and Clinical Activity of KT-413 in Adult Patients With Relapsed or Refractory B-cell NHL

Non Hodgkin Lymphoma | Diffuse Large B Cell Lymphoma | DLBCL | MYD88 Gene Mutation

United States, United Kingdom
Qilu Hospital of Shandong University

Enrolling by invitation

Rapid Identification of MINOCA Based on Novel Biomarkers

Copeptin | Prognosis | Myocardial Infarction With Non-obstructive Coronary Arteries | Grow Stimulation Expressed Gene 2 | Identification

China
National Taiwan University Hospital

Unknown

Genotyping of Non-small Cell Lung Cancer

Non-small Cell Lung Cancer | Gene Abnormality

Taiwan
Prelude Therapeutics

Recruiting

PRT3789 Monotherapy and in Combo w/Docetaxel in Participants w/Advanced or Metastatic Solid Tumors w/SMARCA4 Mutation

Advanced Solid Tumor | Metastatic Solid Tumor | Non-small Cell Lung Cancers | SMARCA4 Gene Mutation

United States, France, Spain, Singapore, Netherlands
Center Trials & Treatment

No longer available

Expanded Access for Pembrolizumab (MK-3475)

Glioblastoma Multiforme | Melanoma (Skin) | Melanoma Recurrent | Glioma of Brain | Glioblastoma by Gene Expression Profile

Hong Kong, Belarus, Tajikistan, Uzbekistan
Natera, Inc.

Completed

Concurrent Single Gene and 24 Chromosome Aneuploidy Preimplantation Genetic Diagnosis (PGD) (IVF008)

Any Single Gene Disorder (Cystic Fibrosis, Tay-Sachs)

United States
Cliniques universitaires Saint-Luc- Université...

Recruiting

Early UVFP Management Based on Neurological Evidences (ION-UVFP) - Preliminary Study

Unilateral Vocal Cord Paralysis | Central Auditory Processing Disorder

Belgium
Nanfang Hospital of Southern Medical University
Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University; First People's Hospital... and other collaborators

Completed

Influence of Molecular Abnormalities on Response of VAH vs. VEN+HMA in RR-AML

Refractory Acute Myeloid Leukemia | Relapsed Acute Myeloid Leukemia | Gene Abnormality | Cytogenetic Abnormality

China
Shirish Gadgeel
Merck Sharp & Dohme LLC

Withdrawn

Study of Pembrolizumab With Single Agent Chemotherapy in Elderly Patients With Advanced NSCLC (HFHS 21-01)

Non Small Cell Lung Cancer | PD-L1 Gene Mutation | Advanced Lung Non-Small Cell Carcinoma
TriHealth Inc.
TriHealth Cancer Institute; TriHealth Surgical Institute; TriHealth Ultrasound... and other collaborators

Withdrawn

Neoadjuvant Use of Talimogene Laherparepvec and BRAF/MEK Inhibitor for Advanced Nodal BRAF Mutant Melanoma

Melanoma (Skin) | Tumor Skin | BRAF Gene Mutation | Melanoma Stage IIIb-IVM1a | Metastasis Skin

United States
Hospices Civils de Lyon

Unknown

Interest of the Dosage of Ferritin / Glycosylated Ferritin in COVID-19

the Prognostic Value of Ferritin | Glycosylated Ferritin in SARS-CoV-2 Infection in Hospitalized COVID-19 Patients

France
Centro di Riferimento Oncologico - Aviano

Recruiting

A Study to Evaluate the Combination of Platinum-pemetrexed Based Chemotherapy Plus Lorlatinib in ALK Positive Non-Small Cell Lung Cancer (NSCLC) With Exclusively Extracranial Disease Progression on Lorlatinib (ALK-PPL)

Non Small Cell Lung Cancer Metastatic | ALK Gene Mutation

Italy
Fudan University

Recruiting

Gene Abnormalities and Prognosis in Diffuse Large B-cell Lymphoma

Diffuse Large B Cell Lymphoma, Gene Mutation

China
David Williams

Active, not recruiting

Phase I/II Trial of Lentiviral Gene Transfer for SCID-X1 With Low Dose Targeted Busulfan Conditioning

Gene Therapy | Severe Combined Immunodeficiency, X Linked

United States, United Kingdom
Xiuning Le
M.D. Anderson Cancer Center; Eli Lilly and Company

Active, not recruiting

Study of Osimertinib With and Without Ramucirumab in Locally Advanced or Metastatic Non-Small Cell Lung Cancer (NSCLC)

Non Small Cell Lung Cancer | Metastatic Cancer | Advanced Cancer | EGFR Gene Mutation

United States
Turning Point Therapeutics, Inc.

Terminated

A Study of TPX-0131, a Novel Oral ALK Tyrosine Kinase Inhibitor, in Patients With ALK+ Advanced or Metastatic NSCLC

Non-Small Cell Lung Cancer | NSCLC | Non Small Cell Lung Cancer | Advanced Solid Tumor | Metastatic Solid Tumor | ALK Gene Mutation

United States, Australia, Korea, Republic of
Escape Bio, Inc.
Momentum Pharma; Science 37

Terminated

A Natural History Study of Patients With G2019S LRRK2 Parkinson's Disease

Patients With Parkinson's Disease (PD) Caused by the p.Gly2019Ser (G2019S) Pathogenic Mutation of the Leucine-Rich Repeat Kinase 2 (LRRK2) Gene

United States
The Cleveland Clinic

Completed

Genomic Sequencing in Patients With HCM Undergoing Septal Myectomy

Hypertrophic Cardiomyopathy | Genetic Disease | Gene Product Sequence Variation

United States
Nanfang Hospital, Southern Medical University

Recruiting

A Single-arm, Open-label Study of Olverembatinib, CD3/CD19 Bispecific T-cell Engager, and Chidamide in Patients With Newly Diagnosed Ph+ALL (ABC)

Acute Lymphoblastic Leukemia | Philadelphia Chromosome | Adult ALL | Philadelphia-Positive ALL | IKZF1 Gene Mutation

China
Second Xiangya Hospital of Central South University
The First Affiliated Hospital of Nanchang University; Xiangya Hospital of Central... and other collaborators

Recruiting

Exploring the Mechanism of Primary Resistance to Third-generation EGFR-TKIs as First-line Treatment in EGFR-positive Advanced NSCLC (PRECISE Study) (PRECISE)

Lung Cancer, Non-small Cell | Circulating Tumor DNA | EGFR Gene Mutation | EGFR-TKI Resistant Mutation | Primary Resistance

China
Alliance for Clinical Trials in Oncology
National Cancer Institute (NCI); GlaxoSmithKline; Genentech, Inc.; Brain Science...

Recruiting

Vismodegib, FAK Inhibitor GSK2256098, Capivasertib, and Abemaciclib in Treating Patients With Progressive Meningiomas

Intracranial Meningioma | Recurrent Meningioma | NF2 Gene Mutation

United States
SwanBio Therapeutics, Inc.

Active, not recruiting

Study of Disease Progression in Adults With Inherited Forms of Spastic Paraplegia (CYGNET)

AMN | AMN Gene Mutation | X-ALD

United States, Netherlands, Germany
Smith & Nephew, Inc.

Completed

S&P of Q-Fix™ All-Suture Anchor System

Bankart Lesion | Acetabular Labrum Tear | SLAP Lesion | Acromioclavicular Sprain | Capsular Shift/Capsulolabral Reconstruction | Deltoid Repair | Rotator Cuff Repair | Bicep Tendinitis | Extra-capsular Repair | Medial Collateral Ligament | Lateal Collateral Ligament | Posterior Oblique Ligament | IBT | Vastus Medialis and other conditions

United States
Intergroupe Francophone de Cancerologie Thoracique

Completed

Description of Clinical Anatomical Features and Long Term Follow-up for Patients With ALK Rearrangements (CLINALK)

Non-small Cell Lung Cancer | Anaplastic Lymphoma Kinase Gene Mutation

France
Calithera Biosciences, Inc

Terminated

A Study of Sapanisertib in Relapsed/Refractory NFE2L2-Mutated and Wild-Type Squamous Non-Small Cell Lung Cancer

Non-Small Cell Lung Cancer | Squamous Non-small-cell Lung Cancer | NFE2L2 Gene Mutation | Squamous Non-Small Cell Neoplasm of Lung

United States
Hellenic Cooperative Oncology Group

Completed

The Molecular Epidemiology of Epidermal Growth Factor Receptor (EGFR) Mutations in Patients With Advanced EGFR Mutation-positive Non-small Cell Lung Cancer Treated With Afatinib

Non Small Cell Lung Cancer | EGF-R Positive Non-Small Cell Lung Cancer | EGFR Gene Mutation
Eli Lilly and Company

Completed

Observational Study of Somatropin Treatment in Children (GeNeSIS)

Growth Hormone (GH) Deficiency | Short Stature Homeobox Containing Gene (SHOX) Deficiency | SHOX Deficiency-related Disorder | Non-GH-deficient Growth Disorders
Peking University Cancer Hospital & Institute

Completed

Gene Expression Profiling of Breast Cancer Cells Predict the Response of Malignant Pleural Effusion (GMPE)

Breast Neoplasms | Neoplasm Metastasis | Immunotherapy | Gene Expression Profiling

China
American British Cowdray Medical Center

Completed

Meta-Analysis of Stress Myocardial Perfusion Imaging

Coronary Disease | Magnetic Resonance Imaging | Predictive Value of Tests | Hemodynamics | Positron Emission Tomography | Echocardiography | Coronary Angiography | Multidetector Computed Tomography | Echocardiography, Stress | Fractional Flow Reserve, Myocardial | Myocardial Perfusion Imaging | Humans | Perfusion | Single Photon Emission Computed Tomography

Mexico
Shanghai Chest Hospital

Recruiting

Prediction of Anastomotic Complications and Recurrent Laryngeal Nerve Injury Based on Postoperative Early Endoscopic Evaluation

Anastomotic Leak | Esophageal Neoplasm | Anastomotic Stenosis | Recurrent Laryngeal Nerve Injuries | Endoscopic Evaluation

China
Regeneron Pharmaceuticals

Not yet recruiting

First in Human (FIH) Study of ALN-SOD in Adult Participants With Amyotrophic Lateral Sclerosis Associated With Mutation in the SOD1 Gene (SOD1-ALS)

Amyotrophic Lateral Sclerosis (ALS) | Mutation in the Superoxide Dismutase-1 (SOD1) Gene
Morten Mau-Sørensen
Odense University Hospital; Aarhus University Hospital; Aalborg University Hospital

Recruiting

Trastuzumab and Standard Treatment With Chemo- and Immunotherapy as First Line Treatment for HER2 Positive Esophageal Squamous Cell Carcinoma Patients (HERES)

Esophageal Squamous Cell Carcinoma | HER-2 Gene Amplification | HER-2 Protein Overexpression

Denmark
Memorial Sloan Kettering Cancer Center

Recruiting

A Study of Oral Erdafitinib in People With Recurrent Non-Invasive Bladder Cancer

Bladder Cancer | Recurrent Bladder Cancer | FGFR3 Gene Mutation

United States
Hospices Civils de Lyon

Recruiting

Molecular, Pathologic Intra Tumoral Heterogeneity in Malignant Pleural Mesothelioma (SCITH-MESO)

Mesothelioma, Malignant | Pleural Mesothelioma | Gene Abnormality

France

Clinical Trials on Genu Valgus

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Papua New Guinea

Conditions

Rare Diseases

Drug Interventions

Dietary Supplements

Sponsor/Collaborators

Locations