Clinical Trials on Gestational Diabetes Mellitus in South Africa

Total 1073 results

Novo Nordisk A/S

Terminated

A Trial Investigating the Efficacy and Safety of Insulin Detemir Versus Insulin NPH in Combination With Metformin and Diet/Exercise in Children and Adolescents With Type 2 Diabetes Insufficiently Controlled on Metformin With or Without Other Oral Antidiabetic Drug(s) With or Without Basal Insulin (iDEAt2)

Diabetes Mellitus, Type 2 | Diabetes

United States, India, Mexico, Israel, Taiwan, Malaysia, Hungary, Turkey, Morocco, Germany, South Africa, Portugal, Lebanon, Italy, Brazil, Croatia, Egypt, Spain, Russian Federation, Greece, Argentina, Korea, Republic of, Poland, Serbia
Novo Nordisk A/S

Completed

Comparison of NN1250 With Sitagliptin in Subjects With Type 2 Diabetes Never Treated With Insulin (BEGIN™)

Diabetes Mellitus, Type 2 | Diabetes

United States, India, Argentina, Turkey, Canada, South Africa, Mexico
Novo Nordisk A/S

Completed

Long Term Safety Trial to Compare Insulin Treatment With Preprandial Inhaled Human Insulin to s.c. Insulin Aspart Both Combined With NPH in Subjects With Type 1 Diabetes

Diabetes | Diabetes Mellitus, Type 1

Australia
Novo Nordisk A/S

Completed

Comparison of NN1250 With Insulin Glargine in Subjects With Type 2 Diabetes (BEGIN™)

Diabetes Mellitus, Type 2 | Diabetes

United States, Israel, Puerto Rico, Slovakia, Canada, South Africa, United Kingdom, Czech Republic
BioDelivery Sciences International

Completed

The Efficacy and Safety of Clonidine Hydrochloride Topical Gel, vs Clonidine Hydrochloride Gel Comparator to Treat Painful Diabetic Neuropathy

Neuropathy | Painful Diabetic Neuropathy | Diabetic Neuropathy

United States
Arcion Therapeutics Inc

Completed

Efficacy and Safety Study of ARC-4558 for Management of Pain Associated With Painful Diabetic Neuropathy

Painful Diabetic Neuropathy

United States
Novartis Pharmaceuticals

Terminated

Safety and Efficacy of EMA401 in Patients With Painful Diabetic Neuropathy (PDN) (EMPADINE)

Painful Diabetic Neuropathy

Belgium, Austria, Germany, Australia, United Kingdom, Bulgaria, Slovakia, Hungary, Spain, Portugal, France, Poland, Denmark, Norway, Canada, Finland
Janssen Research & Development, LLC
The George Institute for Global Health, Australia

Completed

Evaluation of the Effects of Canagliflozin on Renal and Cardiovascular Outcomes in Participants With Diabetic Nephropathy (CREDENCE)

Diabetes Mellitus, Type 2 | Diabetic Nephropathy

United States, Canada, France, Germany, Poland, Ukraine, United Kingdom, China, Taiwan, Spain, Argentina, Colombia, Mexico, Bulgaria, India, Malaysia, Romania, Serbia, South Africa, Japan, Australia, Korea, Republic of, Chile, New Zealand and more
Hoffmann-La Roche

Completed

Study to Determine the Efficacy, Safety, Tolerability & Pharmacokinetics of RO 205-2349 in Patients With Type 2 Diabetes Mellitus

Diabetes

United States, Panama, Mexico, Estonia, Bulgaria, Romania, Puerto Rico, Switzerland, United Kingdom
Novo Nordisk A/S

Completed

A Research Study to See How Well the New Weekly Medicine IcoSema, Which is a Combination of Insulin Icodec and Semaglutide, Controls Blood Sugar Level in People With Type 2 Diabetes Compared to Insulin Glargine Taken Daily With Insulin Aspart (COMBINE 3)

Diabetes Mellitus, Type 2

India, United States, Thailand, Japan, Germany, Turkey, Hungary, Malaysia, Poland, South Africa, Czechia, Italy, France, Slovenia
Eli Lilly and Company

Terminated

A Study of LY2599506 in Patients With Type 2 Diabetes

Diabetes Mellitus, Type 2

Russian Federation, Puerto Rico, Spain, United States, Australia
Takeda

Completed

Efficacy of Lapaquistat Acetate in Subjects Currently Treated With Lipid-Lowering Therapy.

Type 2 Diabetes

United States, Poland, United Kingdom, Germany, South Africa, Finland, Estonia, Slovakia, Czech Republic
Serodus AS

Completed

SER150 vs Placebo in Diabetic Kidney Disease

Diabetic Kidney Disease

Australia, New Zealand
Mylan Inc.
Mylan GmbH

Completed

Non-inferiority Study to Compare the Efficacy and Safety of Mylan's Insulin Glargine With Lantus® in Type 2 Diabetes Mellitus Patients (INSTRIDE 2) (INSTRIDE 2)

Type 2 Diabetes

United States, Jordan, Korea, Republic of, Slovakia, South Africa, Taiwan
AstraZeneca

Completed

Clinical Utility and Safety of Pramlintide in Subjects With Type 1 and Type 2 Diabetes Mellitus

Type 2 Diabetes Mellitus | Type 1 Diabetes Mellitus

United States
Johnson & Johnson Pharmaceutical Research & Development...

Terminated

A Study of Effectiveness and Safety of JNJ-42160443 in Patients With Diabetic Painful Neuropathy

Diabetic Neuropathy

United States
Ionis Pharmaceuticals, Inc.

Completed

Safety, Tolerability and Efficacy of ISIS-GCGRRx in Patients With Type 2 Diabetes

Type 2 Diabetes

United States
Hoffmann-La Roche

Completed

A Study of Aleglitazar in Combination With Metformin in Patients With Type 2 Diabetes Mellitus Who Are Inadequately Controlled With Sulfonylurea Alone or Sulfonylurea Plus Metformin Therapy

Diabetes Mellitus Type 2

Colombia, United States, Mexico, Guatemala, Argentina
AstraZeneca

Completed

Safety and Efficacy of Saxagliptin Plus Insulin With or Without Metformin

Type 2 Diabetes

Mexico, United States, Poland, Canada, Russian Federation, South Africa, France, Hungary, India, United Kingdom
3M

Completed

Evaluating the Ease of Use of a VAC GranuFoam Bridge Dressing on Diabetic Foot Ulcers Receiving VAC Negative Pressure Wound Therapy

Diabetic Foot Ulcers

United States
Daiichi Sankyo, Inc.

Completed

Colesevelam for Children With Type 2 Diabetes (WELKid DM)

Type 2 Diabetes Mellitus

United States
GlaxoSmithKline

Completed

A Phase 2 Clinical Study to Investigate Effects of Darapladib in Subjects With Diabetic Macular Edema

Retinopathy, Diabetic

Australia, Netherlands, Italy, Germany, Denmark
Marsden Eye Specialists

Completed

To Evaluate the Comparative Efficacy of Lucentis (Ranibizumab) 0.5mg Intravitreal Injection in Patients With Diabetic Macular Oedema (DME) With Well Controlled and Poorly Controlled Diabetes Mellitus (CONTROL)

Diabetic Macular Oedema

Australia
Medical University of South Carolina

Completed

Diabetic Retinopathy and Sickle Trait

Diabetic Retinopathy | Sickle Cell Trait

United States
Jaeb Center for Health Research
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK); National...

Completed

Effect of Diabetes Education During Retinal Ophthalmology Visits on Diabetes Control

Diabetes | Diabetic Retinopathy

United States
Oramed, Ltd.
Integrium

Completed

Phase II Safety and Efficacy Study of Oral ORMD-0801 in Patients With Type 2 Diabetes Mellitus

Diabetes Type 2

United States
AstraZeneca

Completed

A Study to Characterize Regimens of Basal Insulin Intensified With Either Symlin® or Rapid Acting Insulin in Patients With Type 2 Diabetes

Type 2 Diabetes Mellitus

United States
Regeneron Pharmaceuticals

Completed

Study of the Efficacy and Safety of Intravitreal (IVT) Aflibercept for the Improvement of Moderately Severe to Severe Nonproliferative Diabetic Retinopathy (NPDR) (PANORAMA)

Nonproliferative Diabetic Retinopathy

United States, Germany, Hungary, Japan, Puerto Rico, United Kingdom
Eli Lilly and Company
Boehringer Ingelheim

Completed

A Study in Painful Diabetic Neuropathy (COMBO-DN)

Diabetic Neuropathy, Painful

Germany, Italy, Netherlands, Croatia, Australia, France, Turkey, Spain, Canada, Poland, Korea, Republic of, United Kingdom, Sweden, Greece, Mexico, Switzerland
Novo Nordisk A/S

Recruiting

A Research Study to See How Well CagriSema Compared to Semaglutide, Cagrilintide and Placebo Lowers Blood Sugar and Body Weight in People With Type 2 Diabetes Treated With Metformin With or Without an SGLT2 Inhibitor (REIMAGINE 2)

Type 2 Diabetes Mellitus

Korea, Republic of, United States, Hungary, Serbia, Spain, China, Australia, Finland, United Kingdom, Italy, Denmark, Canada, Taiwan, Poland, Germany, Sweden, South Africa, Argentina, Brazil, Bulgaria, Japan, Mexico, Turkey, Greece, Col... and more
Johnson & Johnson Pharmaceutical Research & Development...

Completed

An Efficacy, Safety, and Tolerability Study of Canagliflozin (JNJ-28431754) in Patients With Type 2 Diabetes

Diabetes Mellitus, Type II | Diabetes Mellitus, Non Insulin Dependent

United States, Poland, Bulgaria, India, Malaysia, Romania, Canada, Russian Federation, Argentina, Puerto Rico, Czech Republic, United Kingdom, Mexico
Ligand Pharmaceuticals

Completed

A Study of LGD-6972 in Patients With Type 2 Diabetes Mellitus

Type 2 Diabetes Mellitus

United States
Novo Nordisk A/S

Recruiting

A Research Study to See How Well New Weekly Medicine IcoSema, Which is a Combination of Insulin Icodec and Semaglutide, Controls Blood Sugar Levels in People With Type 2 Diabetes (T2D), Compared to Daily Insulin Glargine (COMBINE 4) (COMBINE 4)

Type 2 Diabetes

United States, China, Italy, Japan, India, Poland, South Africa, Turkey, Greece, Puerto Rico
BioDelivery Sciences International

Completed

Study of Clonidine Hydrochloride Topical Gel, 0.1% in the Treatment of Pain Associated With Diabetic Neuropathy

Neuropathy | Painful Diabetic Neuropathy | Diabetic Neuropathy

United States
Ligand Pharmaceuticals

Completed

Safety, Tolerability, and Efficacy Study of MB07803 Administered to Patients With Type 2 Diabetes Mellitus

Type 2 Diabetes Mellitus

United States
Novo Nordisk A/S

Completed

A Research Study Looking at How Semaglutide Works in People With Type 2 Diabetes in United Kingdom, as Part of Local Clinical Practice (SURE UK) (SURE UK)

Diabetes Mellitus, Type 2

United Kingdom
Pacira Pharmaceuticals, Inc

Completed

Study to Assess the Effects of FX006 on Blood Glucose in Patients With OA of the Knee and Type 2 Diabetes

Type 2 Diabetes Mellitus | Osteoarthritis of the Knee

United States
Novo Nordisk A/S

Completed

A Research Study to Compare Two Types of Insulin, a New Weekly Insulin, Insulin Icodec and an Available Daily Insulin, Insulin Degludec, in People With Type 2 Diabetes Who Use Daily Insulin (ONWARDS 2)

Diabetes Mellitus, Type 2

Poland, United States, Japan, Korea, Republic of, Germany, Bulgaria, South Africa, Portugal, Ukraine
AstraZeneca

Completed

An Observational Study Evaluating SYMLIN® (Pramlintide Acetate) Injection Use in Insulin Using Patients With Type 2 and Type 1 Diabetes

Type 2 Diabetes Mellitus | Type 1 Diabetes Mellitus

United States
Novo Nordisk A/S

Completed

Efficacy and Safety of Oral Semaglutide Versus Liraglutide and Versus Placebo in Subjects With Type 2 Diabetes Mellitus (PIONEER 4)

Diabetes Mellitus, Type 2 | Diabetes

United States, Poland, Croatia, Japan, Slovakia, Germany, Latvia, South Africa, Czechia, United Arab Emirates, Hungary, Ukraine, Puerto Rico
Sanofi

Completed

Efficacy and Safety of Lixisenatide Versus Placebo on Top of Basal Insulin and/or Oral Antidiabetic Treatment in Older Type 2 Diabetic Patients (GetGoal-O)

Type 2 Diabetes

United States, Australia, Bulgaria, Canada, Denmark, Germany, Norway, Peru, Poland, South Africa, Spain, Sweden, United Kingdom
OcuTerra Therapeutics, Inc.
Parexel

Completed

Nesvategrast (OTT166) in Diabetic Retinopathy (DR)

Diabetic Retinopathy

United States, Puerto Rico
Novartis Pharmaceuticals

Completed

VERIFY:A Study to Compare Combination Regimen With Vildagliptin & Metformin Versus Metformin in Treatment-naïve Patients With Type 2 Diabetes Mellitus

Type 2 Diabetes Mellitus

Spain, Poland, South Africa, Taiwan, Hong Kong, Norway, Italy, Bulgaria, Latvia, Lithuania, Germany, Turkey, Argentina, Israel, Korea, Republic of, Dominican Republic, Guatemala, Brazil, Colombia, Peru, Philippines, Russian Federation and more
Garvan Institute of Medical Research

Completed

Optimising Health in Type 1 Diabetes

Diabetes Mellitus

Australia
Bristol-Myers Squibb

Completed

Safety Study of BMS-770767 in Subjects With Type 2 Diabetes

Diabetes Type 2

United States, Canada, Korea, Republic of, Australia
Eli Lilly and Company

Completed

A Study for Patients With Type 2 Diabetes Mellitus

Diabetes Mellitus, Type 2

Puerto Rico, United States, Romania, United Kingdom, Spain, Mexico, Austria, South Africa, Germany, Ukraine, India
Valo Health, Inc.

Active, not recruiting

Phase 2 Spectra Study to Evaluate the Safety and Efficacy of OPL-0401 in Patients With Diabetic Retinopathy (Spectra)

Proliferative Diabetic Retinopathy | Non-proliferative Diabetic Retinopathy

United States
Jaeb Center for Health Research
National Eye Institute (NEI); Genentech, Inc.

Completed

Prompt Panretinal Photocoagulation Versus Ranibizumab+Deferred Panretinal Photocoagulation for Proliferative Diabetic Retinopathy (Protocol S)

Proliferative Diabetic Retinopathy

United States
Hoffmann-La Roche

Completed

A Study of Taspoglutide Versus Exenatide for the Treatment of Patients With Type 2 Diabetes Mellitus Inadequately Controlled With Metformin, Thiazolidinedione or a Combination of Both.

Diabetes Mellitus Type 2

Sweden, United States, Mexico, South Africa, Russian Federation, France, Spain, Switzerland, Canada, Finland, New Zealand, Korea, Republic of, Thailand, Israel, Germany, Peru, Australia, Denmark, Italy, Ukraine, Greece, Puerto Rico, Guatemal... and more
Novo Nordisk A/S

Completed

Efficacy and Safety of Biphasic Insulin Aspart 30 in Subjects With Type 2 Diabetes

Diabetes Mellitus, Type 2 | Diabetes

Malaysia, Australia, Taiwan, Thailand, Hong Kong, Singapore, Philippines

Clinical Trials on Gestational Diabetes Mellitus in South Africa

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