Clinical Trials on Glioblastoma Multiforme/Anaplastic Astrocytoma

Total 1705 results

Mashhad University of Medical Sciences

Unknown

Efficacy of Two Temozolomide Regimens in Adjuvant Treatment of Patients With Brain High Grade Glioma

Glioblastoma Multiforme of Brain | Anaplastic Astrocytoma of Brain

Iran, Islamic Republic of
Northwell Health

Completed

Super-Selective Intraarterial Cerebral Infusion of Cetuximab (Erbitux) for Treatment of Relapsed/Refractory GBM and AA

GBM | Anaplastic Astrocytoma | Glioblastoma Multiforme (GBM) | ANAPLASTIC ASTROCYTOMA (AOA)

United States
University of Alabama at Birmingham
National Cancer Institute (NCI)

Active, not recruiting

Genetically Engineered HSV-1 Phase 1 Study for the Treatment of Recurrent Malignant Glioma (M032-HSV-1)

Recurrent Glioblastoma Multiforme | Progressive Glioblastoma Multiforme | Anaplastic Astrocytoma or Gliosarcoma

United States
Lawrence Recht
Nektar Therapeutics

Completed

Phase II NKTR-102 In Bevacizumab-Resistant High Grade Glioma

Anaplastic Astrocytomas | Glioblastomas (GBM) | Anaplastic Oligodendrogliomas

United States
Children's Hospital Medical Center, Cincinnati

Terminated

Treatment of Newly Diagnosed Brain Tumors With Chemotherapy and Radiation Using Cells Modified for Chemoprotection and an Experimental Drug to Decrease the Tumor Cell Resistance to Chemotherapy

Glioblastoma Multiforme (WHO Grade IV) | Anaplastic Astrocytoma (WHO Grade III)

United States
Ohio State University Comprehensive Cancer Center

Completed

Temozolomide and Radiation Therapy in Treating Patients With Newly Diagnosed Glioblastoma Multiforme or Anaplastic Astrocytoma

Glioblastoma Multiforme/Anaplastic Astrocytoma

United States
Amgen

Completed

AMG 595 First-in-Human in Recurrent Gliomas

Glioblastoma Multiforme | Advanced Malignant Glioma | Anaplastic Astrocytomas

United States, Australia
Weill Medical College of Cornell University
Eisai Inc.

Withdrawn

Examination of Changes on Magnetic Resonance Imaging (MRI) and Magnetic Resonance Spectroscopy (MRS) in Patients Who Receive Gliadel Wafers During Initial Surgery for Glioblastoma Multiforme. Response or Failure to Gliadel Wafers for Subjects With Glioblastoma Multiforme. (Gliadel-MRS)

Glioblastoma Multiforme | Anaplastic Astrocytoma | Anaplastic Oligodendroglioma

United States
National Taiwan University Hospital

Withdrawn

Photodynamic Therapy in the Treatment of Malignant Intracranial Tumors

Glioblastoma Multiforme | Anaplastic Ependymoma | Anaplastic Astrocytomas | Anaplastic Oligodendrogliomas | Malignant Intracranial Tumors

Taiwan
Teva Branded Pharmaceutical Products R&D, Inc.
National Cancer Institute (NCI)

Terminated

Phase 2 Trial Using Talampanel in Patients With Recurrent High Grade Gliomas

Glioblastoma Multiforme | Anaplastic Astrocytoma | Anaplastic Oligodendroglioma | Anaplastic Mixed Oligoastrocytoma
Annick Desjardins
Bristol-Myers Squibb

Withdrawn

Ph. I Dasatinib/Protracted Temozolomide in Recurrent Malignant Glioma

Glioma | Glioblastoma Multiforme | Gliosarcoma | Anaplastic Astrocytoma | Anaplastic Oligodendroglioma

United States
Tocagen Inc.

Completed

Study of a Retroviral Replicating Vector Given Intravenously to Patients Undergoing Surgery for Recurrent Brain Tumor

Glioblastoma Multiforme | Anaplastic Oligoastrocytoma | Anaplastic Astrocytoma | Anaplastic Oligodendroglioma

United States
Tocagen Inc.

Completed

Study of a Retroviral Replicating Vector Combined With a Prodrug to Treat Patients Undergoing Surgery for a Recurrent Malignant Brain Tumor

Glioblastoma Multiforme | Anaplastic Oligoastrocytoma | Anaplastic Astrocytoma | Anaplastic Oligodendroglioma

United States
University of Alabama at Birmingham

Not yet recruiting

Re-Administration of C134 in Patients With Recurrent GBM (C134-HSV-1)

Recurrent Malignant Glioma | Glioblastoma Multiforme of Brain | Anaplastic Astrocytoma of Brain | Gliosarcoma of Brain

United States
National Cancer Institute (NCI)

Terminated

(11C)dLop as a Marker of P-Glycoprotein Function in Patients With Gliomas

Glioblastoma Multiforme | Oligoastrocytoma | Anaplastic Astrocytoma | Anaplastic Oligodendroglioma | Low Grade Glioma

United States
National Cancer Institute (NCI)

Completed

A Randomized Phase II Trial of Vandetanib (ZD6474) in Combination With Carboplatin Versus Carboplatin Alone Followed by Vandetanib Alone in Adults With Recurrent High-Grade Gliomas

Glioblastoma Multiforme | Gliosarcoma | Anaplastic Astrocytoma | Anaplastic Oligodendroglioma | Anaplastic Mixed Oligoastrocytoma

United States
Northwell Health
Feinstein Institute for Medical Research; Hofstra North Shore

Completed

Super-Selective Intraarterial Cerebral Infusion Of Temozolomide (Temodar) For Treatment Of Newly Diagnosed GBM And AA

Glioblastoma Multiforme | Anaplastic Astrocytoma

United States
Pediatric Brain Tumor Consortium
National Cancer Institute (NCI); American Lebanese Syrian Associated Charities...

Active, not recruiting

INCB7839 in Treating Children With Recurrent/Progressive High-Grade Gliomas

Glioblastoma Multiforme | Anaplastic Astrocytoma | Anaplastic Oligodendroglioma | DIPG | High-grade Astrocytoma NOS | CNS Primary Tumor, NOS (Malignant Glioma)

United States
Vanquish Oncology, Inc.
University of Illinois at Chicago

Terminated

Procaspase Activating Compound-1 (PAC-1) in the Treatment of Advanced Malignancies - Component 2

Glioblastoma Multiforme | Anaplastic Astrocytoma

United States
Northwell Health
Feinstein Institute for Medical Research

Recruiting

Repeated Super-selective Intraarterial Cerebral Infusion of Bevacizumab (Avastin) for Treatment of Relapsed GBM and AA

Glioblastoma Multiforme | Anaplastic Astrocytoma

United States
Northwell Health

Suspended

Repeated Super-selective Intraarterial Cerebral Infusion Of Bevacizumab Plus Carboplatin For Treatment Of Relapsed/Refractory GBM And Anaplastic Astrocytoma

Glioblastoma Multiforme | Anaplastic Astrocytoma

United States
University of Erlangen-Nürnberg Medical School

Completed

Immunophenotyping From Blood of Patients With Malignant Gliomas

Glioblastoma Multiforme | Anaplastic Astrocytoma

Germany
Northwell Health

Completed

Super-Selective Intraarterial Intracranial Infusion of Avastin (Bevacizumab)

Glioblastoma Multiforme | Anaplastic Astrocytoma

United States
University Hospital, Brest

Unknown

FET-PET and Multiparametric MRI for High-grade Glioma Patients Undergoing Radiotherapy (IMAGG)

Glioblastoma Multiforme | Anaplastic Astrocytoma | Radiotherapy

France
Drexel University

Unknown

Access Protocol for MAB-425 Radiolabeled With I-125 for High Grade Gliomas

Glioblastoma Multiforme | Astrocytoma Anaplastic Foci
Candel Therapeutics, Inc.

Completed

Phase 1b Study of AdV-tk + Valacyclovir Combined With Radiation Therapy for Malignant Gliomas (BrTK01)

Glioblastoma Multiforme | Malignant Glioma | Anaplastic Astrocytoma

United States
Haukeland University Hospital
University of Bergen

Terminated

The Effect of Radiotherapy and Temozolomide on the Tumor Vasculature and Stem Cells in Human High-grade Astrocytomas (Gliomstudien)

Glioblastoma Multiforme | Anaplastic Astrocytoma | Tumor Angiogenesis

Norway
National Cancer Institute (NCI)

Completed

AZD8055 for Adults With Recurrent Gliomas

Glioblastoma Multiforme | Malignant Glioma | Anaplastic Astrocytoma | Anaplastic Oligodendroglioma | Brainstem Glioma

United States
INSYS Therapeutics Inc

Completed

Imaging Study of the Distribution of IL13-PE38QQR Infused Before and After Surgery in Adult Patients With Recurrent Malignant Glioma

Glioblastoma Multiforme | Malignant Glioma | Anaplastic Astrocytoma | Anaplastic Oligodendroglioma | Mixed Oligoastrocytoma

United States
Ann & Robert H Lurie Children's Hospital of Chicago
Northwestern University

Terminated

Trial of Heat Shock Protein Peptide Complex-96 (HSPPC-96) Vaccine

Glioblastoma Multiforme | Ependymoma | Anaplastic Ependymoma | Astrocytoma, Grade III | Clear Cell Ependymoma

United States
Northwestern University
National Cancer Institute (NCI)

Completed

Neural Stem Cell Based Virotherapy of Newly Diagnosed Malignant Glioma

Glioma | Brain Cancer | Glioblastoma Multiforme | Anaplastic Oligoastrocytoma | Anaplastic Astrocytoma | Anaplastic Oligodendroglioma | Astrocytoma, Grade III | Astrocytoma, Grade IV

United States
Guoqiang Yu
National Cancer Institute (NCI); Bioptics Technology LLC; Kentucky Small Business...

Recruiting

Loupe-Based Intraoperative Fluorescence Imaging

Glioblastoma Multiforme | Anaplastic Astrocytoma

United States
Pediatric Brain Tumor Consortium
National Cancer Institute (NCI); Treovir, LLC; American Lebanese Syrian Associated...

Not yet recruiting

HSV G207 With a Single Radiation Dose in Children With Recurrent High-Grade Glioma

Neoplasms | Malignant Glioma of Brain | Glioblastoma Multiforme | High Grade Glioma | Giant Cell Glioblastoma | High-grade Glioma | Anaplastic Astrocytoma of Brain | Anaplastic Glioma

United States
Tocagen Inc.

Terminated

The Toca 5 Trial: Toca 511 & Toca FC Versus Standard of Care in Patients With Recurrent High Grade Glioma (Toca5)

Glioblastoma Multiforme | Anaplastic Astrocytoma

United States, Korea, Republic of, Canada, Israel
National Cancer Institute (NCI)

Terminated

Genetic Analysis of Brain Tumors

Glioma | Astrocytoma | Glioblastoma Multiforme | Anaplastic Astrocytoma | Oligodendroglioma

United States
University of Colorado, Denver

Withdrawn

Fluorescein vs. iMRI in Resection of Malignant High Grade Glioma

Glioblastoma Multiforme | Anaplastic Astrocytoma | High Grade Malignant Neoplasm

United States
Light Sciences Oncology

Completed

Phase IIa Safety and Light Dose-escalation Study in Patients With Primary or Recurrent/High-grade Glioma Using the Litx™ System to Confirm the Zone of Tumor Destruction During the Intraoperative Treatment of Glioma

Glioma | Glioblastoma Multiforme | Anaplastic Astrocytoma

Serbia
University of Alabama at Birmingham
National Cancer Institute (NCI); Gateway for Cancer Research

Recruiting

Trial of C134 in Patients With Recurrent GBM (C134-HSV-1)

Glioblastoma Multiforme of Brain | Anaplastic Astrocytoma of Brain | Gliosarcoma of Brain

United States
All India Institute of Medical Sciences, Bhubaneswar

Not yet recruiting

Ga-68 Prostate Specific Membrane Antigen PET/CT in Gliomas

Glioma | Astrocytoma | Glioblastoma Multiforme | Anaplastic Astrocytoma | Oligodendroglioma

India
Candel Therapeutics, Inc.

Completed

Phase 2a Study of CAN-2409 With Standard Radiation Therapy for Malignant Glioma (BrTK02)

Glioblastoma Multiforme | High Grade Glioma | Malignant Glioma | Anaplastic Astrocytoma

United States
Maastricht Radiation Oncology

Withdrawn

Re-irradiation of High Grade Gliomas: a Quality of Life Study

Glioblastoma Multiforme | Anaplastic Oligoastrocytoma | Anaplastic Astrocytoma

Netherlands
University of Alabama at Birmingham

Recruiting

Study of Pembrolizumab and M032 (NSC 733972)

Glioblastoma Multiforme | Gliosarcoma | Anaplastic Astrocytoma

United States
Macarena De La Fuente, MD

Completed

Dendritic Cell (DC) Vaccine for Malignant Glioma and Glioblastoma

Glioblastoma Multiforme | High Grade Glioma | Malignant Glioma | Anaplastic Astrocytoma

United States
INSYS Therapeutics Inc

Completed

Histologic Effect/Safety of Pre/Post-Operative IL13-PE38QQR in Recurrent Resectable Supratentorial Malignant Glioma Patients

Glioblastoma Multiforme | Malignant Glioma | Anaplastic Astrocytoma | Mixed Oligoastrocytoma | Malignant Astrocytoma

United States
INSYS Therapeutics Inc

Completed

IL13-PE38QQR Infusion After Tumor Resection, Followed by Radiation Therapy With or Without Temozolomide in Patients With Newly Diagnosed Malignant Glioma

Glioblastoma Multiforme | Oligoastrocytoma | Anaplastic Astrocytoma

United States
Sidney Kimmel Comprehensive Cancer Center at Johns...

Completed

Low Dose Radiation Therapy for Glioblastoma Multiforme

High Grade Glioma

United States
Northwell Health
Genentech, Inc.

Completed

Oral Tarceva Study for Recurrent/Residual Glioblastoma Multiforme and Anaplastic Astrocytoma

Glioblastoma Multiforme | Anaplastic Astrocytoma

United States
Northwestern University

Terminated

Efficacy of Hypofractionated XRT w/Bev. + Temozolomide for Recurrent Gliomas

Adult Anaplastic Astrocytoma | Adult Anaplastic Ependymoma | Adult Anaplastic Oligodendroglioma | Adult Giant Cell Glioblastoma | Adult Glioblastoma

United States
OncoSynergy, Inc.
Infuseon Therapeutics, Inc.

Terminated

Convection-enhanced Delivery of OS2966 for Patients With High-grade Glioma Undergoing a Surgical Resection

Glioblastoma | Glioblastoma Multiforme | High Grade Glioma | Anaplastic Astrocytoma | Glioma, Malignant

United States
INSYS Therapeutics Inc

Completed

Pre-operative IL13-PE38QQR in Patients With Recurrent or Progressive Malignant Glioma

Glioblastoma Multiforme | Malignant Glioma | Anaplastic Astrocytoma | Mixed Oligoastrocytoma

United States, Germany, Israel

Clinical Trials on Glioblastoma Multiforme/Anaplastic Astrocytoma

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Malta

Conditions

Rare Diseases

Drug Interventions

Dietary Supplements

Sponsor/Collaborators

Locations