Clinical Trials on Grade IV Malignant Glioma in United Kingdom

Total 962 results

H. Lee Moffitt Cancer Center and Research Institute
Merck Sharp & Dohme LLC

Completed

Hypofractionated Stereotactic Irradiation (HFSRT) With Pembrolizumab and Bevacizumab for Recurrent High Grade Gliomas

Malignant Glioma

United States
University of Florida

Completed

Study of Capecitabine to Treat Recurrent High Grade Gliomas

Malignant Glioma

United States
Sidney Kimmel Comprehensive Cancer Center at Johns...
National Cancer Institute (NCI)

Terminated

Determining Dose of Regadenoson Most Likely to Transiently Alter the Integrity of the Blood-Brain Barrier in Patients With High Grade Gliomas

Glioblastoma | High Grade Glioma | Anaplastic Astrocytoma | Anaplastic Oligodendroglioma

United States
National Cancer Institute (NCI)

Terminated

Geldanamycin Analogue in Treating Patients With Advanced Solid Tumors or Non-Hodgkin's Lymphoma

Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue | Nodal Marginal Zone B-cell Lymphoma | Recurrent Adult Burkitt Lymphoma | Recurrent Adult Diffuse Large Cell Lymphoma | Recurrent Adult Diffuse Mixed Cell Lymphoma | Recurrent Adult Diffuse Small Cleaved Cell Lymphoma and other conditions

United States
Sanofi

Completed

Study of the Poly (ADP-ribose) Polymerase-1 (PARP-1) Inhibitor BSI-201 in Patients With Newly Diagnosed Malignant Glioma

Glioblastoma

United States
Northwest Biotherapeutics

Active, not recruiting

Study of a Drug [DCVax®-L] to Treat Newly Diagnosed GBM Brain Cancer (GBM)

Glioma | Glioblastoma | Brain Cancer | Brain Tumor | Glioblastoma Multiforme | GBM | Grade IV Astrocytoma

United States, Germany, Canada, United Kingdom
Marcela V. Maus, M.D.,Ph.D.

Recruiting

CARv3-TEAM-E T Cells in Glioblastoma

Glioblastoma | Malignant Glioma | Recurrent Glioblastoma | Recurrent Glioma

United States
Duke University
GlaxoSmithKline; Genentech, Inc.

Completed

Avastin/Radiation (XRT)/Temozolomide (Temodar) Followed by Avastin/Temodar/Topotecan for Glioblastoma

Glioblastoma | Malignant Glioma | Gliosarcoma

United States
Sidney Kimmel Comprehensive Cancer Center at Johns...
Bristol-Myers Squibb; National Cancer Institute (NCI); Candel Therapeutics, Inc.

Active, not recruiting

GMCI, Nivolumab, and Radiation Therapy in Treating Patients With Newly Diagnosed High-Grade Gliomas (GMCI)

Glioma, Malignant

United States
Pediatric Brain Tumor Consortium
National Cancer Institute (NCI); American Lebanese Syrian Associated Charities...

Recruiting

A Trial of Dabrafenib, Trametinib and Hydroxychloroquine for Patients With Recurrent LGG or HGG With a BRAF Aberration

Low Grade Glioma (LGG) of Brain With BRAF Aberration | High Grade Glioma (HGG) of the Brain With BRAF Aberration | Low Grade Glioma of Brain With Neurofibromatosis Type 1

United States
National Cancer Institute (NCI)

Completed

Rituximab Plus Interleukin-2 in Treating Patients With Hematologic Cancer

Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue | Nodal Marginal Zone B-cell Lymphoma | Recurrent Adult Burkitt Lymphoma | Recurrent Adult Diffuse Large Cell Lymphoma | Recurrent Adult Diffuse Mixed Cell Lymphoma | Recurrent Adult Diffuse Small Cleaved Cell Lymphoma and other conditions

United States
Stony Brook University

Active, not recruiting

Effect H2 Water on QoL of Patients Receiving Radiotherapy for High Grade Gliomas.

Malignant Glioma

United States
Candel Therapeutics, Inc.

Completed

Phase 1b Study of AdV-tk + Valacyclovir Combined With Radiation Therapy for Malignant Gliomas (BrTK01)

Glioblastoma Multiforme | Malignant Glioma | Anaplastic Astrocytoma

United States
Frank Lieberman
Oncovir, Inc.

Completed

Vaccination-Dendritic Cells With Peptides for Recurrent Malignant Gliomas

Malignant Glioma

United States
H. Lee Moffitt Cancer Center and Research Institute
Cephalon

Terminated

Nuvigil or Placebo in Newly Diagnosed Malignant Glioma

Malignant Glioma

United States
Sidney Kimmel Comprehensive Cancer Center at Johns...

Completed

Low Dose Radiation Therapy for Glioblastoma Multiforme

High Grade Glioma

United States
Dana-Farber Cancer Institute

Withdrawn

GROW (Glioma Specialists Reaching Out With Support) Support

Low-grade Glioma | Survivorship | Care Giving Burden

United States
Patrick Y. Wen, MD
Massachusetts General Hospital; Northwestern University; Novartis; Beth Israel... and other collaborators

Completed

LBH589 and Bevacizumab in Patients With Recurrent High Grade Glioma

Malignant Glioma

United States
Eli Lilly and Company

Completed

A Study of LY317615 in Patients With Brain Tumors

Malignant Glioma

United States
Duke University
Pfizer

Completed

Ph. II Treatment of Adults w Primary Malignant Glioma w Irinotecan + Temozolomide

Glioblastoma

United States
National Cancer Institute (NCI)

Terminated

(11C)dLop as a Marker of P-Glycoprotein Function in Patients With Gliomas

Glioblastoma Multiforme | Oligoastrocytoma | Anaplastic Astrocytoma | Anaplastic Oligodendroglioma | Low Grade Glioma

United States
National Cancer Institute (NCI)

Completed

Temozolomide and O6-Benzylguanine in Treating Children With Recurrent Brain Tumors

Recurrent Childhood Medulloblastoma | Recurrent Childhood Ependymoma | Childhood Choroid Plexus Tumor | Childhood Craniopharyngioma | Childhood Ependymoblastoma | Childhood Grade I Meningioma | Childhood Grade II Meningioma | Childhood Grade III Meningioma | Childhood High-grade Cerebellar Astrocytoma | Childhood High-grade Cerebral Astrocytoma and other conditions

United States
National Cancer Institute (NCI)

Completed

Cilengitide in Treating Children With Refractory Primary Brain Tumors

Recurrent Childhood Medulloblastoma | Recurrent Childhood Ependymoma | Childhood Choroid Plexus Tumor | Childhood Craniopharyngioma | Childhood Ependymoblastoma | Childhood Grade I Meningioma | Childhood Grade II Meningioma | Childhood Grade III Meningioma | Childhood High-grade Cerebellar Astrocytoma | Childhood High-grade Cerebral Astrocytoma and other conditions

United States
Darell Bigner
Rockefeller University

Recruiting

Phase 1 Trial of D2C7-IT in Combination With 2141-V11 for Recurrent Malignant Glioma

Glioma, Malignant

United States
University of Michigan Rogel Cancer Center
Phase One Foundation

Completed

Combined Cytotoxic and Immune-Stimulatory Therapy for Glioma

Glioblastoma Multiforme | Malignant Glioma

United States
Duke University
Genentech, Inc.

Completed

Radiosurgery and Avastin for Recurrent Malignant Gliomas

Malignant Glioma

United States
Wake Forest University Health Sciences
National Cancer Institute (NCI)

Terminated

Adherence Monitoring System in Managing Myelosuppression in Patients With Newly Diagnosed Malignant Gliomas Receiving Temozolomide and Radiation Therapy

Malignant Glioma | Myelosuppression

United States
Pfizer

Terminated

First in Patient Study for PF-06840003 in Malignant Gliomas

Astrocytoma | Malignant Glioma | Oligodendroglioma

United States
Mayo Clinic
National Cancer Institute (NCI)

Completed

Intrapleural Measles Virus Therapy in Patients With Malignant Pleural Mesothelioma

Recurrent Malignant Mesothelioma | Stage IA Malignant Mesothelioma | Stage IB Malignant Mesothelioma | Stage II Malignant Mesothelioma | Stage III Malignant Mesothelioma | Stage IV Malignant Mesothelioma

United States
National Cancer Institute (NCI)

Completed

Valproic Acid With Temozolomide and Radiation Therapy to Treat Brain Tumors

Brain Tumors | High Grade Gliomas

United States
NanoPharmaceuticals LLC

Recruiting

Safety and Tolerability of Fb-PMT in Recurrent Glioblastoma

Glioma, Malignant

United States
Duke University

Recruiting

The PCSK9i Inhibitor Evolocumab - a Surgical Trial of Pharamcodynamics and Kinetics Evaluation

Glioblastoma | Malignant Glioma

United States
Case Comprehensive Cancer Center

Terminated

Lenalidomide And Rituximab as Maintenance Therapy in Treating Patients With B-Cell Non-Hodgkin Lymphoma

Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue | Nodal Marginal Zone B-cell Lymphoma | Recurrent Adult Burkitt Lymphoma | Recurrent Adult Diffuse Large Cell Lymphoma | Recurrent Adult Diffuse Mixed Cell Lymphoma | Recurrent Adult Diffuse Small Cleaved Cell Lymphoma and other conditions

United States
Eben Rosenthal
National Institutes of Health (NIH)

Active, not recruiting

Panitumumab-IRDye800 in Diagnosing Participants With Malignant Glioma Undergoing Surgery

Malignant Glioma | Malignant Brain Neoplasm

United States
Dana-Farber Cancer Institute
Memorial Sloan Kettering Cancer Center; Massachusetts General Hospital; University... and other collaborators

Withdrawn

MK-2206 for Recurrent Malignant Glioma

Malignant Glioma

United States
MediGene
National Cancer Institute (NCI)

Completed

G207 Followed by Radiation Therapy in Malignant Glioma

Malignant Glioma

United States
National Cancer Institute (NCI)

Active, not recruiting

Telaglenastat With Radiation Therapy and Temozolomide in Treating Patients With IDH-Mutated Diffuse Astrocytoma or Anaplastic Astrocytoma

Astrocytoma, IDH-Mutant, Grade 2 | Astrocytoma, IDH-Mutant, Grade 3

United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Active, not recruiting

Ultra Low Dose Orbital Radiation Therapy in Treating Patients With Stage I-IV Indolent B-cell Lymphoma or Mantle Cell Lymphoma

Ann Arbor Stage I Grade 1 Follicular Lymphoma | Ann Arbor Stage I Grade 2 Follicular Lymphoma | Ann Arbor Stage II Grade 1 Follicular Lymphoma | Ann Arbor Stage II Grade 2 Follicular Lymphoma | Ann Arbor Stage IV B-Cell Non-Hodgkin Lymphoma | Ann Arbor Stage I B-Cell Non-Hodgkin Lymphoma | Ann... and other conditions

United States
National Cancer Institute (NCI)
Children's Oncology Group

Active, not recruiting

Tazemetostat in Treating Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders With EZH2, SMARCB1, or SMARCA4 Gene Mutations (A Pediatric MATCH Treatment Trial)

Recurrent Hodgkin Lymphoma | Refractory Hodgkin Lymphoma | Rhabdoid Tumor | Advanced Malignant Solid Neoplasm | Refractory Malignant Solid Neoplasm | Ann Arbor Stage III Hodgkin Lymphoma | Ann Arbor Stage IV Hodgkin Lymphoma | Recurrent Ependymoma | Recurrent Ewing Sarcoma | Recurrent Hepatoblastoma | Recurrent... and other conditions

United States, Puerto Rico
St. Jude Children's Research Hospital

Completed

Study of the Combination of Crizotinib and Dasatinib in Pediatric Research Participants With Diffuse Pontine Glioma (DIPG) and High-Grade Glioma (HGG)

Diffuse Intrinsic Pontine Glioma | High-grade Glioma

United States
Dana-Farber Cancer Institute
National Institutes of Health (NIH); Candel Therapeutics, Inc.

Recruiting

A Study of the Treatment of Recurrent Malignant Glioma With rQNestin34.5v.2 (rQNestin)

Glioma | Glioblastoma | Astrocytoma | Malignant Glioma of Brain | Brain Cancer | Brain Tumor | Glioblastoma Multiforme | Ependymoma | Ganglioglioma | Oligodendroglioma | Malignant Astrocytoma | Anaplastic Oligodendroglioma of Brain (Diagnosis) | Mixed Oligo-Astrocytoma | Pylocytic/Pylomyxoid Astrocytoma

United States
Annick Desjardins
Symphogen A/S

Completed

Phase 2 Study of Sym004 for Adult Patients With Recurrent Glioblastoma

Malignant Glioma

United States
OHSU Knight Cancer Institute
National Cancer Institute (NCI)

Completed

Ferumoxytol in Improving MR Imaging in Patients With High-Grade Brain Tumors or Cerebral Metastases

Malignant Glioma | Metastatic Malignant Neoplasm in the Brain | Central Nervous System Lymphoma

United States
Gary Archer Ph.D.
Bristol-Myers Squibb; Duke Cancer Institute

Completed

Nivolumab With DC Vaccines for Recurrent Brain Tumors (AVERT)

Glioblastoma | Astrocytoma | Malignant Glioma

United States
Katy Peters
Amgen

Completed

AMG 102 and Avastin for Recurrent Malignant Glioma

Glioblastoma Multiforme | Gliosarcoma

United States
National Cancer Institute (NCI)

Completed

FAU in Treating Patients With Advanced Solid Tumors or Lymphoma

Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue | Nodal Marginal Zone B-cell Lymphoma | Recurrent Adult Burkitt Lymphoma | Recurrent Adult Diffuse Large Cell Lymphoma | Recurrent Adult Diffuse Mixed Cell Lymphoma | Recurrent Adult Diffuse Small Cleaved Cell Lymphoma and other conditions

United States
Baylor Research Institute
National Cancer Institute (NCI); National Institutes of Health (NIH)

Completed

IL15 Dendritic Cell Vaccine for Patients With Resected Stage III (A, B or C) or Stage IV Melanoma

Malignant Melanoma Stage III | Malignant Melanoma Stage IV

United States
Oncolytics Biotech

Completed

Safety and Efficacy Study of REOLYSIN® in the Treatment of Recurrent Malignant Gliomas

Malignant Glioma

United States
Nader Sanai
AstraZeneca; Barrow Neurological Institute; Ivy Brain Tumor Center

Recruiting

AZD1390 in Recurrent and Newly Diagnosed WHO Grade 4 Glioma Patients

Glioma | Glioblastoma | Glioblastoma Multiforme | Glioma, Malignant

United States
Eudocia Quant Lee, MD
University of California, San Diego; Beth Israel Deaconess Medical Center; Dartmouth-Hitchcock... and other collaborators

Completed

A Randomized Placebo-Controlled Trial of Armodafinil (Nuvigil) for Fatigue in Patients With Malignant Gliomas

Malignant Glioma

United States

Clinical Trials on Grade IV Malignant Glioma in United Kingdom

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