Clinical Trials on Gram-Negative Bacterial Infections

Total 7947 results

GlaxoSmithKline

Completed

The Long-term Antibody Persistence of GSK Biologicals' Meningococcal Vaccine GSK134612 in Healthy Toddlers

Infections, Meningococcal

United States
GlaxoSmithKline

Completed

Meningococcal Quadrivalent CRM-197 Conjugate Vaccine Pregnancy Registry

Pregnancy | Meningococcal Disease | Infections, Meningococcal

United States
Novartis
Novartis Vaccines

Completed

Immunogenicity, Safety and Tolerability, of Chiron Meningococcal C Conjugate Vaccine Administered to Healthy Premature and Non Premature Children of 3 Months of Age

Prevention of Meningococcal Infection

Italy
London School of Hygiene and Tropical Medicine

Completed

Impact Evaluation of Urban Water Supply Improvements on Cholera and Other Diarrhoeal Diseases in Uvira, Democratic Republic of Congo

Diarrhea | Cholera

Congo, The Democratic Republic of the
International Vaccine Institute
International Centre for Diarrhoeal Disease Research, Bangladesh; Christian... and other collaborators

Terminated

Safety and Immunogenicity of Peru-15 Vaccine When Given With Measles Vaccine in Healthy Indian and Bangladeshi Infants

Diarrhea | Cholera | Vibrio Infections

Bangladesh, India
Johns Hopkins University
National Institutes of Health (NIH)

Recruiting

Biodistribution and Pathophysiology Study of 18F-Fluorodeoxysorbitol (18F-FDS) in Diseased Patients

Invasive Fungal Infections | Inflammatory Disease | Oncologic Disease | Enterobacterial Infections

United States
University Hospital, Basel, Switzerland
Stiftung Forschung Infektionskrankheiten, Basel, Switzerland

Completed

Simplified GBS Screening and Prevalence of ESBL in Pregnant Women

Group B Streptococcal Infection | Infection Due to ESBL Bacteria

Switzerland
Hunazine Biotech S.L.

Recruiting

Assessment of a Novel Fixed-dose Combination (FDC) Drug VR-AD-1005 for the Treatment of Acute Watery Diarrhea in Cholera

Cholera

Bangladesh
International Centre for Diarrhoeal Disease Research...
Stanford University; Centers for Disease Control and Prevention

Recruiting

Immunogenicity of Co-administered Oral Polio Vaccine and Oral Cholera Vaccine

Vaccine Reaction

Bangladesh
Brigham and Women's Hospital
Harvard Medical School (HMS and HSDM); National Institute of Allergy and Infectious... and other collaborators

Completed

Evaluation of a Pilot Program to Introduce Cholera Vaccine in Haiti as Part of Global Cholera Control Efforts

Diarrhea | Cholera

Haiti
PATH

Terminated

High Amylose Maize Starch for Treatment of Cholera (RESTORS)

Diarrhea

Bangladesh
Dalhousie University
National Institute of Allergy and Infectious Diseases (NIAID); Vanderbilt University... and other collaborators

Recruiting

Establishing a Controlled Human Infection Model of Bordetella Pertussis

Pertussis

Canada
Sanofi Pasteur, a Sanofi Company

Completed

Safety and Immunogenicity of a Quadrivalent Meningococcal Tetanus Protein Conjugate Vaccine in Toddlers

Meningitis | Meningococcal Infection

Australia
National Institute of Allergy and Infectious Diseases...

Completed

Trial of Azithromycin vs. Doxycycline for the Treatment of Rectal Chlamydia in MSM

Anal Chlamydia Infection

United States
Arkansas Children's Hospital Research Institute

Withdrawn

Chlamydia Trachomatis Persistence in the Female Gastrointestinal Tract

Chlamydia Infection

United States
University of California, San Francisco
University of Alabama at Birmingham

Completed

Self-Obtained Vaginal Swabs for Chlamydia and Gonorrhea Testing (SOVS-CTG)

Gonococcal Infection | Chlamydial Infection

United States
Eunice Kennedy Shriver National Institute of Child...

Terminated

Hormonal Contraception and Risk of Chlamydia and Gonorrhea

Chlamydia Infection | Neisseriaceae Infection
University of Pittsburgh

Completed

Community - Associated Extended-spectrum Beta-lactamases (ESBL)

Infection | Proteus Infections | Klebsiella Infections | E Coli Infections

United States
Sir Run Run Shaw Hospital

Unknown

Epidemiology of Klebsiella Pneumoniae in China

Klebsiella Pneumoniae Infection

China
U.S. Army Medical Research and Development Command

Enrolling by invitation

Continued Safety and Immunogenicity Study of a Live Francisella Tularensis Vaccine

Tularemia

United States
GlaxoSmithKline
Biological E. Limited

Recruiting

Safety and Immunogenicity of a Novel Conjugate Vaccine Against Salmonella Typhi and Salmonella Paratyphi A in Healthy Adults

Typhoid Fever

Belgium
GlaxoSmithKline
Bill and Melinda Gates Foundation; Wellcome Trust; Biomedical Advanced Research... and other collaborators

Recruiting

A Study to Evaluate Safety, Reactogenicity, and Immune Response of GVGH iNTS-TCV Vaccine Against Invasive Nontyphoidal Salmonella and Typhoid Fever

Salmonella Infections

Belgium, Malawi
EuBiologics Co.,Ltd

Completed

Non-inferiority and Safety Study of EuTCV Compared to Typbar-TCV in Healthy 6 Months-45 Years Aged Participants

Typhoid Fever

Philippines
Novartis Vaccines

Completed

Persistence Of Antibody Responses Among Children Who Previously Received Novartis MenACWY Conjugate Vaccine or Meningococcal C Conjugate Vaccine

Meningococcal Disease

Germany
Novartis
Novartis Vaccines

Completed

Safety and Immunogenicity of Novartis Meningococcal B Vaccine When Administered to Immunocompromised Children and Adolescents Compared to Healthy Subjects.

Meningococcal Disease

Italy, Poland, Russian Federation, Spain, United Kingdom
Novartis Vaccines
Novartis

Completed

Safety and Immunogenicity Study of Two Doses of Novartis Meningococcal Serogroup B Recombinant Vaccine in Adolescents Aged 11-17 Years.

Meningococcal Disease

Korea, Republic of
Novartis Vaccines

Completed

Safety Surveillance of MenACWY-CRM Vaccine in Children

Meningococcal Disease

United States
National Institute of Allergy and Infectious Diseases...

Completed

CVD 909 Vi Prime Boost Study

Typhoid Fever

United States
Novartis

Completed

Extension Study of H01_04TP to Evaluate the Booster Response Induced by Vi-CRM197 in Adults

Typhoid Fever

Belgium
Novartis

Completed

Safety and Immunogenicity of Vi-CRM197 Vaccine Against S. Typhi in Adult (18-40 Years Old)

Typhoid Fever

Belgium
GlaxoSmithKline

Completed

Effectiveness of GlaxoSmithKline Biologicals S.A's Meningococcal Group B and Combined ABCWY Vaccines in Healthy Adolescents and Young Adults

Infections, Meningococcal

United States, Australia, Finland, Estonia, Canada, Turkey, Czechia
GlaxoSmithKline

Completed

Study to Assess the Safety and Immunogenicity of a Single Dose of GlaxoSmithKline's (GSK) Meningococcal MenACWY-CRM Vaccine (Menveo), Administered to Subjects 15 Through 55 Years of Age, Approximately 4-6 Years After Primary ACWY Vaccination

Infections, Meningococcal

United States, Puerto Rico
GlaxoSmithKline

Completed

Safety and Immunogenicity of GlaxoSmithKline Biologicals Meningococcal Group B Vaccine When Administered Concomitantly With GlaxoSmithKline Biologicals MenACWY Conjugate Vaccine to Healthy Infants

Infections, Meningococcal

Mexico, Argentina
National Institute of Allergy and Infectious Diseases...

Recruiting

Phase 2 Shigella Vaccine and Challenge

Immunisation | Shigella Infection

United States
Canadian Paediatric Society
GlaxoSmithKline; Pfizer

Recruiting

Enhanced Population-based Core Surveillance of Meningococcal Invasive Infections at Participating Centers Across Canada

Invasive Meningococcal Disease

Canada
Bavarian Nordic
Emergent BioSolutions

Completed

Phase 4 Study To Assess The Safety Of Vivotif At Different Release Titers Among Travelers

Typhoid Fever

United States
Canadian Immunization Research Network
University of British Columbia; Canadian Institutes of Health Research (CIHR); Alberta Health services and other collaborators

Completed

Adolescent MenACWY Booster Study

Meningococcal Disease, Invasive

Canada
Eunice Kennedy Shriver National Institute of Child...

Completed

Long Term Protection by and Persistence of Vi Antibodies Induced by Vi-rEPA Conjugate Vaccines in Vietnamese Children Injected at 2-5 Years or at 5-8 Years of Age

Typhoid Fever

United States, Vietnam
Novartis Vaccines

Completed

Persistence of Immunogenicity of MenACWY Conjugate Vaccine 5 Years After Childhood Vaccination, and Immune Response to a Booster Dose

Meningococcal Disease

United States, Ukraine
Novartis

Completed

Safety and Immunogenicity of Vi-CRM197 Vaccine Against S. Typhi in Adults, Children, Older Infants and Infants

Typhoid Fever

Pakistan, India
Novartis

Completed

Safety and Immunogenicity of Vi-CRM197 Vaccine Against S. Typhi in Children, Older Infants and Infants

Typhoid Fever

Philippines
Center for Vaccine Development - Mali
University College, London; University of Oxford; Public Health England; University... and other collaborators

Recruiting

A Human Controlled Infection Study With Neisseria Lactamica in Malian Adults

Meningitis, Meningococcal

Mali
Johns Hopkins Bloomberg School of Public Health
National Institute of Allergy and Infectious Diseases (NIAID); International... and other collaborators

Recruiting

Cholera-Hospital-Based-Intervention-for-7-Days (CHoBI7) Water, Sanitation, and Hygiene (WASH) Case Area Targeted Intervention (CATI)

Diarrhea | Cholera

Bangladesh
University of Florida
National Institute of Allergy and Infectious Diseases (NIAID)

Recruiting

Next Generation ORS: Controlled Trial Comparing ORS With Calcium vs Standard ORS in Reducing Severity of Acute Watery Diarrhea (ORS)

Diarrhea | Cholera

Bangladesh
Institut Pasteur

Recruiting

Study of the Incidence of Jarisch-Herxheimer Reaction in Leptospirosis Patients in New Caledonia (LEPJARNC)

Leptospirosis | Jarisch Herxheimer Reaction

New Caledonia
PATH

Completed

PK Study of iOWH032 in Adult Male/Female Healthy Volunteers & Adult Males With Cholera (PISCES)

Diarrhea | Cholera

Bangladesh
International Vaccine Institute
Indian Council of Medical Research; Institute of Child Health; National Institute... and other collaborators

Unknown

Safety and Immunogenicity of a Killed Oral Cholera Vaccine in Infants

Diarrhea | Cholera | Vibrio Infections

India
International Vaccine Institute
National Institute of Cholera and Enteric Diseases, India; Shantha Biotechnics...

Completed

Randomized Controlled Trial of Killed Oral Cholera Vaccine in Kolkata

Diarrhea | Cholera | Vibrio Infections

India
International Vaccine Institute
Bill and Melinda Gates Foundation; World Health Organization; National Institute... and other collaborators

Completed

Mass Oral Cholera Vaccination in Zanzibar

Diarrhea | Cholera

Tanzania
International Vaccine Institute
National Institute of Cholera and Enteric Diseases, India; Shantha Biotechnics...

Completed

Immunogenicity of One Versus Two Doses of Killed Oral Cholera Vaccine

Diarrhea | Cholera | Vibrio Infections

India

Clinical Trials on Gram-Negative Bacterial Infections

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CROs in Netherlands

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Rare Diseases

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