Clinical Trials on H3 K27M in South Africa

Total 8 results

  • Chimerix
    Recruiting
    ONC201 in H3 K27M-mutant Diffuse Glioma Following Radiotherapy (the ACTION Study) (ACTION)
    Glioma | H3 K27M
    United States, Australia, Canada, Spain, Switzerland, Israel, Germany, Italy, United Kingdom, Korea, Republic of, Netherlands, Denmark, Austria
  • University of California, San Francisco
    National Institute of Neurological Disorders and Stroke (NINDS); The Chad-Tough... and other collaborators
    Recruiting
    Combination Therapy for the Treatment of Diffuse Midline Gliomas
    Diffuse Intrinsic Pontine Glioma | Diffuse Midline Glioma, H3 K27M-Mutant | Recurrent Diffuse Intrinsic Pontine Glioma | Recurrent Diffuse Midline Glioma, H3 K27M-Mutant | Recurrent WHO Grade III Glioma | WHO Grade III Glioma
    United States, Israel, Australia, Netherlands, Switzerland, New Zealand
  • Oblato, Inc.
    Available
    Expanded Access to OKN-007 for Patients With Diffuse Midline Glioma, H3 K27-altered
    Diffuse Intrinsic Pontine Glioma | Diffuse Midline Glioma, H3 K27M-Mutant
    United States
  • Nationwide Children's Hospital
    Novartis
    Not yet recruiting
    Study of Ribociclib and Everolimus in HGG and DIPG
    Glioblastoma | Glioblastoma Multiforme | High Grade Glioma | Anaplastic Astrocytoma | Diffuse Intrinsic Pontine Glioma | Diffuse Midline Glioma, H3 K27M-Mutant | WHO Grade III Glioma | Metastatic Brain Tumor | WHO Grade IV Glioma
    United States, Australia, United Kingdom, Canada, Germany, Netherlands
  • Nationwide Children's Hospital
    Not yet recruiting
    Targeted Pediatric High-Grade Glioma Therapy
    Glioblastoma | Glioblastoma Multiforme | High Grade Glioma | Anaplastic Astrocytoma | Diffuse Intrinsic Pontine Glioma | Diffuse Midline Glioma, H3 K27M-Mutant | WHO Grade III Glioma | Metastatic Brain Tumor | WHO Grade IV Glioma
    United States, Australia, United Kingdom, Canada, Germany, Netherlands
  • National Cancer Institute (NCI)
    Suspended
    A Study of the Drug Selinexor With Radiation Therapy in Patients With Newly-Diagnosed Diffuse Intrinsic Pontine (DIPG) Glioma and High-Grade Glioma (HGG)
    Glioblastoma | Malignant Glioma | Anaplastic Astrocytoma | Anaplastic Astrocytoma, Not Otherwise Specified | Diffuse Intrinsic Pontine Glioma | Diffuse Midline Glioma, H3 K27M-Mutant | Glioblastoma, Not Otherwise Specified
    United States, Canada, Australia, New Zealand
  • Rigel Pharmaceuticals
    Nationwide Children's Hospital
    Not yet recruiting
    Study of Olutasidenib and Temozolomide in HGG
    Astrocytoma | High Grade Glioma | Oligodendroglioma | Diffuse Intrinsic Pontine Glioma | Diffuse Midline Glioma, H3 K27M-Mutant | WHO Grade III Glioma | Metastatic Brain Tumor | Spinal Tumor | Astrocytoma, Grade III | Astrocytoma, Grade IV | IDH1 Mutation | WHO Grade IV Glioma | Thalamus Tumor | IDH1 R132 | IDH1 R132C | IDH1 R132H and other conditions
    United States, Australia, United Kingdom, Canada, Germany, Netherlands
  • Aminex Therapeutics, Inc.
    Recruiting
    Oral AMXT 1501 Dicaprate in Combination With IV DFMO
    Melanoma | Cervical Cancer | Cancer | Breast Cancer | Head and Neck Cancer | Gastric Cancer | Colorectal Cancer | Esophageal Cancer | Solid Tumor | Endometrial Cancer | Advanced Cancer | Diffuse Midline Glioma, H3 K27M-Mutant | Papillary Thyroid Cancer | Solid Carcinoma | Mesotheliomas Pleural | Glioma, Malignant | Ovary Cancer and other conditions
    United States, Australia

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