Clinical Trials on HER2-positive in Switzerland

Total 94 results

OnkoZentrum Zürich AG
University of Zurich; Palleos Healthcare GmbH

Completed

HER2-directed Biosimilar in Breast Cancer: Real World ePRO (OGIPRO)

HER2-positive Breast Cancer | Biosimilar | Patient Reported Outcome

Switzerland
ETOP IBCSG Partners Foundation
Pfizer; Hoffmann-La Roche

Completed

To Reduce the Use of Chemotherapy in Postmenopausal Patients With ER-positive and HER2-positive Breast Cancer (TOUCH) (TOUCH)

Breast Cancer | HER2-positive Breast Cancer | Estrogen Receptor Positive Tumor

France, Switzerland, Belgium, Italy
AstraZeneca

Recruiting

Phase III Study to Assess AZD9833+ CDK4/6 Inhibitor in HR+/HER2-MBC With Detectable ESR1m Before Progression (SERENA-6) (SERENA-6)

ER-Positive HER2-Negative Breast Cancer

United States, Israel, Spain, Korea, Republic of, Italy, Poland, Belgium, Norway, Bulgaria, France, Germany, United Kingdom, Japan, Taiwan, Canada, Hungary, Australia, Austria, Portugal, Turkey, Russian Federation, Slovakia, Switzer...
Prof. Wolfgang Janni
Eli Lilly and Company

Recruiting

Combination of Abemaciclib and Endocrine Therapy in Hormone Receptor Positive HER2 Negative Locally Advanced or Metastatic Breast Cancer With Focus on Digital Side Effect Management (MINERVA)

Hormone Receptor-positive Metastatic Breast Cancer | HER2-negative Metastatic Breast Cancer

Germany, Switzerland
Seagen Inc.
Merck Sharp & Dohme LLC

Recruiting

A Study of Tucatinib or Placebo With Trastuzumab and Pertuzumab for Metastatic HER2+ Breast Cancer (HER2CLIMB-05)

HER2 Positive Breast Cancer

United States, Taiwan, Canada, Korea, Republic of, Austria, China, Spain, Japan, France, Italy, Switzerland, Australia, Belgium, Brazil, Germany, Portugal, United Kingdom, Netherlands, Czechia, Greece, Chile, Finland, Poland
Seagen Inc.

Recruiting

A Study of Tucatinib vs. Placebo in Combination With Ado-trastuzumab Emtansine (T-DM1) for Patients With Advanced or Metastatic HER2+ Breast Cancer

HER2-positive Breast Cancer

United States, Australia, Austria, Belgium, Canada, China, Denmark, France, Germany, Israel, Italy, Japan, Korea, Republic of, Netherlands, Singapore, Spain, Sweden, Switzerland, Taiwan, United Kingdom
AstraZeneca

Active, not recruiting

A Comparative Study of AZD9833 Plus Palbociclib Versus Anastrozole Plus Palbociclib in Patients With ER-Positive HER2 Negative Breast Cancer Who Have Not Received Any Systemic Treatment for Advanced Disease (SERENA-4)

ER-Positive HER2-Negative Breast Cancer

Austria, Belgium, France, Germany, Italy, United Kingdom, United States, Canada, India, Taiwan, Russian Federation, Korea, Republic of, Hungary, Japan, Mexico, Turkey, China, Malaysia, Spain, Czechia, Portugal, Poland, Norway, Bulgaria, Slovaki... and more
Seagen Inc.

Completed

A Study of Tucatinib vs. Placebo in Combination With Capecitabine & Trastuzumab in Patients With Advanced HER2+ Breast Cancer (HER2CLIMB)

HER2 Positive Breast Cancer

United States, Spain, Belgium, Germany, Israel, France, United Kingdom, Austria, Denmark, Italy, Australia, Canada, Czechia, Portugal, Switzerland
Shanghai Zhongshan Hospital
Fudan University; University Hospital, Basel, Switzerland; Zhongshan Hospital... and other collaborators

Recruiting

Individualized PEEP Titration on Postoperative Pulmonary Complications

Laparoscopic Surgery | Elderly | Postoperative Pulmonary Complications | Positive End-expiratory Pressure

China, Switzerland
University Children's Hospital Basel

Recruiting

Electrical Impedance Tomography for Identification of Optimal Positive End-expiratory Pressure in Newborn Infants

Positive End-expiratory Pressure (PEEP)

Switzerland
Hôpital Fribourgeois

Recruiting

Effect of Positive Therapeutic Communication on Pain (POPAIN)

Effect of Positive Therapeutic Communication on Pain

Switzerland
University of Zurich

Unknown

Daptomycin Pharmacokinetics in Critically Ill Patients Undergoing Continuous Veno-venous Hemodiafiltration, a Dose Finding Study

Gram-Positive Bacterial Infections

Switzerland
Jules Bordet Institute
Hoffmann-La Roche; Breast International Group; Institut Curie; International Drug...

Suspended

De-escalation Adjuvant Chemo in HER2+/ER-/Node-neg Early BC Patients Who Achieved pCR After Neoadjuvant Chemo & Dual HER2 Blockade (Decrescendo)

HER2-positive Breast Cancer | ER-Negative Breast Cancer | PR-Negative Breast Cancer | Node-negative Breast Cancer

Korea, Republic of, France, Israel, Belgium, Switzerland, Australia
GlaxoSmithKline

Completed

Safety and Immunogenicity of GSK Biological's Candidate Tuberculosis Vaccine Mtb72F/AS02A in Healthy PPD-positive Adults

Tuberculosis (TB)

Switzerland
University Hospital, Basel, Switzerland
Fachhochschule Nordwestschweiz

Withdrawn

miRNA in Sweat, a Novel Digital Biomarker for Detection of Active Tuberculosis (TB)

Active Tuberculosis

Switzerland
GlaxoSmithKline

Completed

Safety and Immunogenicity of a Candidate Tuberculosis (TB) Vaccine in HIV-positive Adults.

Tuberculosis

Switzerland
University Children's Hospital Basel

Terminated

Comparative Trial of Oral Penicillin Versus Cefuroxim for Treatment of Perianal Streptococcal Dermatitis

Streptococcal Infections

Switzerland
University Hospital, Basel, Switzerland

Completed

Diagnosing of Acute Tuberculosis (SwEaTB)

Tuberculosis

Switzerland
University Hospital, Geneva

Completed

An Ecological Analysis of Nontuberculous Mycobacteria in the Geneva Area (2015-2020)

Ecology of Nontubercuous Mycobacteria | Geneva Area

Switzerland
Aeras
Sanofi Pasteur, a Sanofi Company

Completed

A Study for Safety and Immunogenicity of BCG and AERAS-404 in HIV-Negative, TB-Negative, BCG-Naive Adults (C-013-404)

Tuberculosis

Switzerland
University of Zurich

Recruiting

Safety and Tolerability of Chlorquine in Addition to Anti-tuberculosis Therapy

Tuberculosis Infection

Switzerland
University Hospital, Geneva
Ligue Pulmonaire Genevoise

Completed

Results of an Interferon-Gamma Release Assay After Treatment for Tuberculosis

Tuberculosis

Switzerland
University Hospital, Geneva
Ligue Pulmonaire Genevoise

Completed

Use of a Gamma-IFN Assay in Contact Tracing for Tuberculosis in a Low-Incidence, High Immigration Area

Tuberculosis | Latent Tuberculosis Infection

Switzerland
University Hospital, Basel, Switzerland
propatient foundation Basel

Completed

Probability of Target Attainment With Standard Intermittent Bolus Administration of Cefazolin in Patients With Complicated Infections Caused by Staphylococcus Aureus (TARGET II)

Staphylococcus Aureus Infection

Switzerland
François Spertini
University of Oxford

Completed

ChAdOx1 85A Aerosol Versus Intramuscular Vaccination in Healthy Adults (TB039) (TB039)

Tuberculosis | Mycobacterium Tuberculosis, Protection Against

Switzerland
University Hospital, Basel, Switzerland

Completed

Prosthetic Valve and Graft Endocarditis With Mycobacterium Chimaera

Mycobacterium Chimaera Infections

Switzerland
University Hospital, Geneva
Swiss National Science Foundation; University of Applied Sciences of Western...

Completed

Maternal Positioning and Occipitoposterior Fetal Position

Dystocia | Maternal Distress in Labor | Persistent Occipitoposterior or Occipitoanterior Position | Fetal Position and Presentation Abnormalities

Switzerland
Benoit Guery

Recruiting

Fecal Microbiota Transplantation in Clostridioides Difficile Infection First Episode and First Recurrence (FENDER)

Clostridioides Difficile Infection

Switzerland
University Hospital, Basel, Switzerland
Stiftung Forschung Infektionskrankheiten, Basel, Switzerland

Completed

Simplified GBS Screening and Prevalence of ESBL in Pregnant Women

Group B Streptococcal Infection | Infection Due to ESBL Bacteria

Switzerland
Biofabri, S.L
Centre Hospitalier Universitaire Vaudois; TuBerculosis Vaccine Initiative; Universidad...

Completed

Dose-Escalation Study to Evaluate the Safety and Immunogenicity of MTBVAC Vaccine in Comparison With BCG Vaccine. (MTBVAC)

Healthy | Tuberculosis

Switzerland
Ligue Pulmonaire Genevoise

Completed

Interferon Gamma Release Assays (IGRA) Testing Versus Tuberculin Skin Test in Renal Transplant Recipients

Latent Tuberculosis Infection

Switzerland
University Hospital, Basel, Switzerland

Recruiting

Target Attainment of Continuous Infusion Flucloxacillin and Cefazolin Coupled With TDM vs. Standard of Care Treatment in Patients With Complicated S. Aureus Infection (TARGET III)

Complicated Staphylococcus Aureus (S. Aureus) Infections (CSAI)

Switzerland
Sanofi

Completed

Study of an Investigational Pneumococcal Vaccine in Healthy Adult Volunteers

Pneumococcal Infections | Pneumococcal Pneumonia

Switzerland
Innovative Medicines for Tuberculosis
Bill and Melinda Gates Foundation

Completed

Study to Evaluate the Safety, Tolerability and Pharmacokinetics of PBTZ169 in Multiple Dosing

Tuberculosis, Pulmonary

Switzerland
Andrej Trampuz
University of Lausanne Hospitals; Schulthess Klinik; Kantonsspital Liestal

Unknown

Daptomycin With Rifampin for Treatment of Staphylococcal Prosthetic Joint Infection (Dapto-Studie)

Staphylococcal Infections

Switzerland
Innovative Medicines for Tuberculosis
Bill and Melinda Gates Foundation

Completed

Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Ex-vivo Antitubercular Activity of PBTZ169 Formulation

Tuberculosis | Tuberculosis, Pulmonary

Switzerland
University of Applied Sciences of Western Switzerland
Swiss National Science Foundation; University of Lausanne Hospitals; Réseau d... and other collaborators

Completed

Impact of a Telenursing Service on Satisfaction and Health Outcomes of Children With Inflammatory Rheumatic Diseases

Inflammatory Rheumatism

Switzerland
Novartis Pharmaceuticals

Completed

Real-world Effectiveness of Asciminib and Treatment Patterns in Patients With Chronic Myeloid Leukemia With T315I Mutation - a Chart Review Study of Patients Treated in the Asciminib Managed Access Program (MAP)

Chronic Myeloid Leukemia With T315I Mutation

Switzerland
University of Zurich

Completed

Delayed Antibiotic Treatment in Community-acquired Pneumococcal Pneumonia.

Community-acquired Pneumonia

Switzerland
Juerg Hafner

Recruiting

Painless Sharp Wound Debridement With Lidocaine-23%-Tetra-caine-7% Gel Versus EMLA 5% Cream (LIDOTETRA)

Ulcer, Leg | Ulcus Cruris | Ulcer Venous | Ecthyma

Switzerland
Sanofi

Completed

Study of Two Investigational Pneumococcal Vaccines in Healthy Adults

Pneumococcal Infections | Streptococcus Pneumoniae Infections | Pneumococcal Pneumonia

Switzerland
MerLion Pharmaceuticals GmbH

Terminated

First Time in Man Trial for Friulimicin B

Staphylococcal Skin Infections | Community Acquired Pneumonia

Switzerland
Sanofi Pasteur, a Sanofi Company

Completed

Study of an Investigational Pneumococcal Vaccine at Three Dose Levels in Healthy Adults

Pneumococcal Infections | Streptococcus Pneumoniae Infections | Pneumococcal Pneumonia

Switzerland
University Children's Hospital Basel
University Hospital, Geneva; University Hospital Inselspital, Berne; Kantonsspital... and other collaborators

Recruiting

Diagnosis of Tuberculosis in Swiss Children (CITRUS)

Tuberculosis | Mycobacterium Tuberculosis

Switzerland
University Hospital, Geneva
Ligue Pulmonaire Genevoise

Completed

Detection of Latent Tuberculosis in Hemodialysis Patients

Chronic Renal Failure

Switzerland
University Hospital Inselspital, Berne
Instituto de Cardiología Paredes-Horna, Arequipa; Hospital Nacional Carlos...

Completed

Rheumatic Heart Disease in Peru: Prevalence and Cardiovascular Outcomes Among Schoolchildren

Rheumatic Heart Disease | Acute Rheumatic Fever

Peru, Switzerland
University Hospital, Basel, Switzerland
Swiss Tropical & Public Health Institute; Ifakara Health Institute

Completed

Prevalence of Chronic Kidney Disease (CKD) and Risk Factors in Sub-Saharan Africa (RenalOne)

HIV Infections | Hypertension | Diabetes Mellitus | Chronic Kidney Diseases | Tuberculosis | Schistosomiasis

Switzerland
Swiss Group for Clinical Cancer Research

Completed

Paclitaxel in Treating Patients With Refractory or Recurrent Acute Leukemia or Chronic Myelogenous Leukemia

Leukemia

Switzerland
ETOP IBCSG Partners Foundation
GlaxoSmithKline; Development Limited

Recruiting

Niraparib Added to Anti-PD-L1 Antibody Maintenance in SLFN11-positive, Extensive-disease SCLC (RAISE)

SCLC,Extensive Stage | SLFN11-positive

Switzerland, France, Spain, Italy
Thomas Pilgrim
B.P. Koirala Institute of Health Sciences

Recruiting

Echocardiographic Screening of Pregnant Women During Antenatal Care

Pregnancy Complications | Rheumatic Heart Disease | Valvular Heart Disease

Nepal, Switzerland

Clinical Trials on HER2-positive in Switzerland

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