Clinical Trials on HIV -1 Infection

Total 70470 results

The Crofoot Research Center, Inc.
Janssen Scientific Affairs, LLC

Completed

Rapid Reinitiation of a Single Tablet Antiretroviral Therapy Using Symtuza® in HIV-1 Infected Treatment-Experienced Patients Off Therapy. (ReSTART) (ReSTART)

HIV-1-infection

United States
Merck Sharp & Dohme LLC

Completed

Doravirine/Islatravir (DOR/ISL) in Heavily Treatment-Experienced (HTE) Participants for Human Immunodeficiency Virus Type 1 (HIV-1) Infection (MK-8591A-019)

HIV-1 Infection

United States, Australia, Canada, Chile, Colombia, France, Germany, Italy, Japan, Korea, Republic of, Peru, Portugal, Puerto Rico, Russian Federation, South Africa, Spain, Ukraine, United Kingdom
University of Roma La Sapienza

Unknown

Infectious Diseases and Movement Program: Study of the Effects of Physical Activity on HIV Infection (PRIMO)

HIV-1-infection

Italy
Janssen Pharmaceutica N.V., Belgium

Completed

Study to Assess the Acceptability of Darunavir/Cobicistat/Emtricitabine/Tenofovir Alafenamide (D/C/F/TAF) Fixed-Dose Combination (FDC) Tablets in Human Immunodeficiency Virus Type 1 (HIV-1) Infected Pediatric Participants, Using Matching Placebo Tablets

HIV-1

United States, Spain
Merck Sharp & Dohme LLC

Completed

A Study of Islatravir (MK-8591) in Anti-Retroviral Therapy-Naive, Human Immunodeficiency Virus-1 Infected Participants (MK-8591-003)

HIV-1
Janssen Research & Development, LLC

Completed

Study to Assess the Acceptability/Swallowability of DRV-Containing FDC Tablets in HIV-1 Infected Adolescents, Using Matching Placebo Tablets

HIV-1

United States
Janssen-Cilag Ltd.

Completed

Early Access to Low-dose Ritonavir (TMC114/r) and Other Antiretrovirals (ARVs) for Treatment-naive or Early Treatment Experienced in HIV-1 Patients

HIV-1

Taiwan
Bristol-Myers Squibb

Completed

Korean Post-marketing Surveillance for Reyataz®

HIV-1

Korea, Republic of
Ratiopharm GmbH

Completed

Multiple Dose BE Study With Nevirapine 400mg PR Tablets

HIV-1

United Kingdom
Fundacion para la Investigacion Biomedica del Hospital...
Pfizer

Completed

Effect Of A CCR5 Coreceptor Antagonist On The Latency And Reservoir Of HIV-1

HIV-1

Spain
Pfizer
ViiV Healthcare

Completed

A Study in Asymptomatic HIV Infected Patients to Investigate Pharmacodynamics, Pharmacokinetics, Safety and Toleration of UK-453,061

HIV-1

Germany
ViiV Healthcare
Pfizer

Completed

Trial of Maraviroc (UK-427,857) in Combination With Zidovudine/Lamivudine Versus Efavirenz in Combination With Zidovudine/Lamivudine (MERIT)

HIV-1

United States, Canada, United Kingdom, Netherlands, Argentina, Australia, Belgium, South Africa, Switzerland, Italy, Puerto Rico, Brazil, Mexico, Poland
Gilead Sciences

Completed

ROCKET II - Randomized Open Label Switch for Cholesterol Elevation on Kivexa + Kaletra Evaluation Trial (ROCKET II)

HIV-1

Austria, Germany, Italy, Spain
Swedish Institute for Infectious Disease Control
The Swedish Research Council; European Union; Läkare mot AIDS Forskningsfond

Completed

Dermal HIV-1 Immunization During Anti-retroviral Therapy Followed by Repeated Treatment Interruptions (Vac09)

HIV-1

Sweden
Eunice Kennedy Shriver National Institute of Child...

Completed

Interventions to Decrease the Risk of Mother-to-Child Transmission of HIV in India

HIV-1

United States
ANRS, Emerging Infectious Diseases
Bristol-Myers Squibb

Completed

Pilot Study to Assess the Efficacy of and Tolerance to a QUadruple Therapy to Treat HIV-HCV Coinfected Patients Previously Null Responders (QUADRIH)

HCV-HIV Co-Infection

France
Pfizer

Terminated

A Phase 2B Multicenter, Randomized, Comparative Trial Of UK-453,061 Versus Etravirine In Combination With Darunavir/Ritonavir And A Nucleos(t)Ide Reverse Transcriptase Inhibitor For The Treatment Of Antiretroviral Experienced HIV-1 Infected Subjects With Evidence Of NNRTI Resistant HIV-1

HIV-1

Spain, United Kingdom, Malaysia, United States, Portugal, Brazil, Germany, Italy, Poland, Puerto Rico, South Africa, Taiwan, Ukraine
University of Oxford
Medical Research Council

Terminated

Safety and Immunogenicity of MVA.HIVconsv in HIV-1 Seropositive Adults on HAART

HIV-1

United Kingdom
Christoph Stephan
University Hospital Heidelberg

Completed

Impact of Raltegravir on HIV-1 cDNA Slope Following Antiretroviral Therapy (ART) Initiation

HIV-1

Germany
ViiV Healthcare
Pfizer

Terminated

Comparative Trial Of Maraviroc Versus Emtricitabine/Tenofovir Both With Darunavir/Ritonavir In Antiretroviral-Naive Patients Infected With CCR5 Tropic HIV 1 (MODERN)

HIV-1

United States, Netherlands, Spain, Puerto Rico, Canada, Australia, Germany, Sweden, Poland, Portugal, Switzerland, France, Denmark, Italy, Belgium, United Kingdom, Hungary, Austria, Finland
Tibotec Pharmaceuticals, Ireland

Completed

The TMC125-C214 Study Provides Early Access to TMC125 for HIV-1 Infected Patients Who Have Failed Multiple Antiretroviral Regimens and Will Also Gather Information on the Long-term Safety and Tolerability of TMC125 Combined With Other Antiretroviral Drugs

HIV-1

United States, Belgium, Germany, Taiwan, Spain, Mexico, Turkey, Canada, Netherlands, Denmark, Greece, Sweden, Korea, Republic of, Russian Federation, Puerto Rico, Luxembourg
Juan A. Arnaiz

Completed

Metabolic Effects of Atazanavir/Ritonavir Versus Darunavir/Ritonavir in Combination With Tenofovir/Emtricitabine in naïve HIV-1 Infected Patients

HIV-1

Spain
GlaxoSmithKline

Terminated

Open Label Study of 908/RTV in Combination With Other PIs for the Treatment of Multi PI-Experienced HIV Subjects

HIV-1

Australia, Belgium, Canada, France, Germany, Greece, Italy, Spain, United Kingdom
Rigshospitalet, Denmark
Horizon 2020 - European Commission; IrsiCaixa

Not yet recruiting

The MISTRAL Study: Gut Microbiome Correlates of Serious AIDS and Non-AIDS Events (MISTRAL)

Inflammation | HIV-1-infection | AIDS

Spain, United Kingdom, Denmark, France, Israel, Germany, Belgium, Croatia, Czechia, Greece, Hungary, Italy, Luxembourg, Poland
ANRS, Emerging Infectious Diseases
Imperial College London; University College, London; Fred Hutchinson Cancer Center and other collaborators

Terminated

An HIV Vaccine Trial in Individuals Who Started ART During Primary or Chronic Infection (EHVAT01)

HIV-1-infection

Switzerland, United Kingdom
Lund University
Ethiopian Public Health Institute; Armauer Hansen Research Institute, Ethiopia and other collaborators

Recruiting

HIV Transmission in the Era of Scaling up Antiretroviral Therapy in Ethiopia (THESA)

Antiretroviral Therapy | HIV-1-infection

Ethiopia
Henry M. Jackson Foundation for the Advancement...
US Military HIV Research Program; Janssen Vaccines & Prevention B.V.

Withdrawn

Safety and Efficacy of Neutralizing Antibodies and Vaccination for Induction of HIV Remission (RV582)

HIV-1-infection

Thailand
The Wistar Institute
University of Pennsylvania; Merck Sharp & Dohme LLC

Completed

Pilot Peg-Interferon-a2b in Decreasing Viral DNA in HIV

HIV-1 Infection

United States
Gilead Sciences

Completed

Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Efficacy of E/C/F/TAF Fixed Dose Combination (FDC) in HIV-1 Infected Adults on Chronic Hemodialysis

HIV-1 Infection

United States, France, Austria, Germany
Abbott

Completed

Multicountry, Multicenter Post-Marketing Observational Study of Clinical, Biological and Virological Outcomes, Compliance and Tolerability of Kaletra® in Routine Clinical Use (KaleEAST)

HIV-1 Patients

Czech Republic, Georgia, Israel, Latvia, Lithuania, Poland, Romania, Russian Federation, Serbia, Slovakia, Slovenia, Ukraine
Institute of Tropical Medicine, Belgium
University Hospital, Ghent; Universitair Ziekenhuis Brussel; Agentschap voor... and other collaborators

Completed

Analytical Treatment Interruption in HIV Positive Patients (ISALA)

HIV-1 Infection

Belgium
Mount Sinai Hospital, Canada
CIHR Canadian HIV Trials Network

Unknown

Progesterone Supplementation for HIV-positive Pregnant Women on Anti-Retrovirals (ProSPAR)

HIV-1 Infection

Canada
University of Washington
National Institute of Allergy and Infectious Diseases (NIAID); National Center...

Enrolling by invitation

Comparing Immune Activation and Latent HIV Reservoir Size Between People Living With HIV on Tenofovir-containing Versus NRTI-free ART

Inflammation | HIV | HIV-1-infection | HIV Disease Progression

United States
Gilead Sciences

Not yet recruiting

A Study to Provide Continued Access to Study Drug to Children and Adolescents Who Have Completed Clinical Studies Involving Gilead HIV Treatments

HIV-1-infection
Gilead Sciences

Recruiting

Study to Compare Bictegravir/Lenacapavir Versus Current Therapy in People With HIV-1 Who Are Successfully Treated With Biktarvy (ARTISTRY-2)

HIV-1-infection

United States
Advancing Clinical Therapeutics Globally for HIV...
National Institute of Allergy and Infectious Diseases (NIAID)

Not yet recruiting

Antiretrovirals Combined With Antibodies for HIV-1 Cure In Africa (ACACIA)

HIV-1-infection
Jean-Pierre Routy
St. Joseph's Health Care London

Not yet recruiting

Fecal Microbiota Translantation (FMT) to Reduce Inflammation in PLWH: The Gutsy Pilot Study (Gutsy)

HIV-1-infection
Gilead Sciences

Recruiting

Study of Novel Antiretrovirals in Participants With HIV-1

HIV-1-infection

United States, Thailand, Dominican Republic
Chelsea and Westminster NHS Foundation Trust

Recruiting

Efficacy of Doravirine + Dolutegravir Dual Therapy in the Context of Antiretroviral Therapy Switch (DORDOL)

HIV-1-infection

United Kingdom
University Hospital, Ghent
ViiV Healthcare

Recruiting

2DR Versus 3DR in a Prospective Randomized Controlled Switch Trial (2DR)

HIV-1-infection

Belgium
IrsiCaixa

Completed

Impact of Raltegravir Intensification on HIV-1-infected Subjects With Complete Viral Suppression Under Monotherapy With Protease Inhibitors

HIV-1 Infection

Spain
MSD Pharmaceuticals LLC

Completed

ART First-line Treatment Durability in Russia

HIV-1-infection

Russian Federation
University of Washington
National Institute on Drug Abuse (NIDA); Makerere University

Active, not recruiting

Uganda PrEP and Harm Reduction Evaluation

HIV-1-infection

Uganda
University of Florida
National Institute on Alcohol Abuse and Alcoholism (NIAAA)

Completed

ANCHORS Study: UH2 Project (ANCHORS)

HIV-1-infection

United States
Quest Clinical Research
Gilead Sciences

Completed

Bictegravir/Emtricitabine/Tenofovir Alafenide Plus Doravirine

HIV-1-infection

United States
Centre Hospitalier Universitaire Dijon

Completed

Optimization of HIV-1 DNA Genotyping by High Throughput Sequencing to Document Antiretroviral Resistant Mutations (Mutapro)

HIV-1-infection

France
Gilead Sciences
Merck Sharp & Dohme LLC

Active, not recruiting

Study Evaluating the Safety and Efficacy of Islatravir in Combination With Lenacapavir in Virologically Suppressed People With HIV

HIV-1 Infection

United States
National Institute of Allergy and Infectious Diseases...
National Institutes of Health (NIH); Department of Health and Human Services

Active, not recruiting

Trial to Evaluate the Safety and Immunogenicity of Priming Regimens of 426c.Mod.Core-C4b Adjuvanted With 3M-052-AF + Alum in Healthy, HIV-1 Uninfected Adult Participants

HIV-1-infection

United States
Radboud University Medical Center
Erasmus Medical Center; Elisabeth-TweeSteden Ziekenhuis; Onze Lieve Vrouwe Gasthuis

Completed

2000HIV Trained Innate Immunity in HIV Elite Controllers (2000HIVTrained)

HIV-1-infection

Netherlands
TaiMed Biologics Inc.
Westat

Completed

Study of the Safety of Trogarzo™ Administered as an Undiluted "IV Push" or an Intramuscular Injection

HIV-1-infection

United States

Clinical Trials on HIV -1 Infection

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