Clinical Trials on HIV and Tuberculosis Co-infection in Brazil

Total 1554 results

ANRS, Emerging Infectious Diseases

Recruiting

Tnf Inhibitors to Reduce Mortality in HIV-1 Infected PAtients With Tuberculosis meNIngitis (TIMPANI)

Tuberculous Meningitis | HIV I Infection

Mozambique, Brazil, Zambia
BioMérieux

Completed

Performance Evaluation of the VIDAS TB-IGRA Assay.

Active Tuberculosis | Latent Tuberculosis Infection | Non-Tuberculous Mycobacterial (NTM) Pneumonia

United States, France, United Kingdom, India, Brazil, Georgia, Italy, Mexico, South Africa
Oswaldo Cruz Foundation
Abbott

Completed

An Evaluation of the Pharmacological Interaction of Lopinavir/r and Rifampin (A06-295)

HIV Infection | Tuberculosis

Brazil
Stanford University
National Institute of Allergy and Infectious Diseases (NIAID); Federal University... and other collaborators

Recruiting

Point-of-care Pharmacogenomic Testing to Optimize Isoniazid Dosing for Tuberculosis Prevention

Tuberculosis Infection | Isoniazid Adverse Reaction

Brazil
Stanford University

Terminated

A Study to Determine the Best Dose of Antivirals in Patients With Both TB and HIV (OPTI-NNRTI)

HIV Infections | Tuberculosis

Brazil
National Institute of Allergy and Infectious Diseases...

Recruiting

Trial of a Six-Month Regimen of High-Dose Rifampicin, High-Dose Isoniazid, Linezolid, and Pyrazinamide Versus a Standard Nine-Month Regimen for the Treatment of Adults and Adolescents With Tuberculous Meningitis

Tuberculous Meningitis

South Africa, Zimbabwe, India, Kenya, Malawi, Mexico, Peru, Brazil, Philippines, Tanzania, Thailand, Vietnam
ANRS, Emerging Infectious Diseases
Merck Sharp & Dohme LLC; Ministry of Health, Brazil

Completed

Raltegravir Versus Efavirenz in Naive HIV-1-infected Patients Receiving Rifampin for Active Tuberculosis (REFLATE TB2)

Tuberculosis | HIV-1 Infection

France, Vietnam, Brazil, Côte D'Ivoire, Mozambique
Johns Hopkins University
Bill and Melinda Gates Foundation; Communicable Disease Program, Brazil; Consortium...

Completed

TB (Tuberculosis) Preventive Therapy for HIV Patients With Access to HAART (Highly Active Antiretroviral Therapy)

HIV Infections | Tuberculosis

Brazil
ViiV Healthcare
GlaxoSmithKline

Completed

Open-label Study of Dolutegravir (DTG) or Efavirenz (EFV) for Human Immunodeficiency Virus (HIV) - Tuberculosis (TB) Co-infection

HIV Infections | Infection, Human Immunodeficiency Virus

Mexico, Peru, Thailand, South Africa, Russian Federation, Argentina, Brazil
Federal University of Mato Grosso
Stanford University; Oswaldo Cruz Foundation

Withdrawn

BCG Re-vaccination for Primary Tuberculosis Prophylaxis in the Prison Population (PPT-BCG)

Latent Tuberculosis

Brazil
McGill University
Canadian Institutes of Health Research (CIHR)

Completed

Rifampin Versus Isoniazid for the Treatment of Latent Tuberculosis Infection in Children (P4v9)

Latent Tuberculosis Infection

Canada, Australia, Benin, Brazil, Ghana, Guinea, Indonesia
AIDS Clinical Trials Group
National Institute of Allergy and Infectious Diseases (NIAID)

Terminated

Rifampin-Based Tuberculosis Treatment Versus Rifabutin-Based Tuberculosis Treatment in Persons With HIV

HIV Infection | Tuberculosis

Peru, Brazil, South Africa, Haiti, Kenya
Oswaldo Cruz Foundation
Ministry of Health, Brazil

Terminated

Randomized Clinical Trial to Assess the Efficacy and Safety of Concomitant Use of Rifampicin and Efavirenz 600 X 800mg (IPEC-EFV)

HIV Infections | Tuberculosis

Brazil
McGill University
Canadian Institutes of Health Research (CIHR)

Completed

Randomized Clinical Trial Comparing 4RIF vs. 9INH for LTBI Treatment-effectiveness

Latent Tuberculosis Infection

Canada, Australia, Benin, Brazil, Ghana, Indonesia, Guinea, Korea, Republic of, Saudi Arabia
McGill University Health Centre/Research Institute...
Canadian Institutes of Health Research (CIHR)

Completed

GXT - GeneXpert or Chest-X-ray or Tuberculin Skin Testing for Household Contact Assessment

Latent Tuberculosis

Benin, Brazil
Fundação de Medicina Tropical Dr. Heitor Vieira...

Unknown

RIPE vs RIPE Plus N-acetylcysteine in Patients With HIV/TB Co-infection (RIPENACTB)

HIV/AIDS | Tuberculosis, Pulmonary

Brazil
Centers for Disease Control and Prevention
US Department of Veterans Affairs

Completed

Three Months of Weekly Rifapentine and Isoniazid for M. Tuberculosis Infection (PREVENT TB)

Tuberculosis

United States, Canada, Spain, Brazil
AIDS Clinical Trials Group
National Institute of Allergy and Infectious Diseases (NIAID)

Completed

REMEMBER: Reducing Early Mortality & Morbidity by Empiric Tuberculosis (TB) Treatment (REMEMBER)

HIV Infection

Peru, Malawi, Uganda, South Africa, India, Haiti, Zambia, Zimbabwe, Brazil, Kenya
AIDS Clinical Trials Group
National Institute of Allergy and Infectious Diseases (NIAID)

Completed

Immediate Versus Deferred Start of Anti-HIV Therapy in HIV-Infected Adults Being Treated for Tuberculosis (STRIDE)

HIV Infection | Tuberculosis

United States, Peru, Kenya, Malawi, Uganda, Brazil, South Africa, Zimbabwe, India, Thailand, Botswana, Haiti, Zambia
Hospital de Clinicas de Porto Alegre
Federal University of Rio Grande do Sul

Completed

Intervention in the Management of Post-high Tuberculosis Hospital Through Educational Strategy and Oversight Distance

Pulmonary Tuberculosis | Extra Pulmonary Tuberculosis

Brazil
Federal University of Uberlandia

Completed

Structural and Functional Repercussions of Pulmonary Tuberculosis Sequelae

Pulmonary Tuberculosis

Brazil
National Institute of Allergy and Infectious Diseases...

Completed

A Cluster-Randomized Trial of DOTS vs DOTS Plus Active Case Finding

Mycobacterium Tuberculosis

Brazil
National Institute of Allergy and Infectious Diseases...

Completed

Brief Rifapentine-Isoniazid Evaluation for TB Prevention (BRIEF TB)

HIV Infections | Tuberculosis

Brazil, United States, Kenya, Peru, South Africa, Thailand, Botswana, Haiti, Malawi, Zimbabwe
Ataulpho de Paiva Foundation
Bill and Melinda Gates Foundation

Completed

Xpert MTB/Rif, a New Tool for the Diagnosis of Pulmonary Tuberculosis in Two Municipalities in Brazil

Tuberculosis

Brazil
ANRS, Emerging Infectious Diseases
Merck Sharp & Dohme LLC; Gilead Sciences

Completed

Efficacy and Safety of 2 Raltegravir Doses in Naive HIV-1-infected Patients Receiving Rifampin for Active Tuberculosis

HIV Infections | Tuberculosis

France, Brazil
Johns Hopkins University
Universidade Federal do Rio de Janeiro

Terminated

Rifapentine Plus Moxifloxacin for Treatment of Pulmonary Tuberculosis

Tuberculosis

Brazil
Universidade Federal de Goias

Completed

Profile of HIV Seropositive Patients (PHSP)

HIV Infections | HIV Infection

Brazil
National Institute of Allergy and Infectious Diseases...

Completed

Early Bactericidal Activity of Linezolid, Gatifloxacin, Levofloxacin, Isoniazid (INH) and Moxifloxacin in HIV Negative Adults With Initial Episodes of Sputum Smear-Positive Pulmonary Tuberculosis

Tuberculosis

United States, Brazil
AIDS Clinical Trials Group
National Institute of Allergy and Infectious Diseases (NIAID); National Institute...

Completed

Observational Study of Specificity of Mycobacterium Tuberculosis Screening and Diagnostics in HIV-Infected Individuals

HIV Infections | Tuberculosis

Peru, South Africa, Botswana, Brazil, India, Malawi, Zimbabwe
Federal University of Mato Grosso
Oswaldo Cruz Foundation

Terminated

Prevention of Tuberculosis in Prisons

Tuberculosis, Pulmonary | Antibiotic Prophylaxis

Brazil
Universidade Federal do Rio de Janeiro

Recruiting

Cardiopulmonary Function and Quality of Life in Pulmonary Tuberculosis

Quality of Life | Tuberculosis, Pulmonary | Physical Disability

Brazil
Federal University of São Paulo
Fundação de Amparo à Pesquisa do Estado de São Paulo; Conselho Nacional de... and other collaborators

Completed

Multi Interventional Study Exploring HIV-1 Residual Replication: a Step Towards HIV-1 Eradication and Sterilizing Cure

HIV | Chronic Infection

Brazil
Johns Hopkins University
Universidade Federal do Rio de Janeiro

Completed

Innovative Approaches to Tuberculosis Control

Tuberculosis

Brazil
Oswaldo Cruz Foundation

Completed

A Bioequivalence Study of Two Different Dosages of Isoniazid Tablet Formulations in Human Healthy Volunteers

Tuberculosis

Brazil
National Institute of Allergy and Infectious Diseases...

Completed

A Randomized Trial of DOTS Versus Enhanced DOTS for Community Control of Tuberculosis

Tuberculosis

Brazil
Sociedade Cearense de Infectologia

Completed

Study of Health Personnel and the Assistance to Patients With Tuberculosis in Hospital Environment

Tuberculosis | Health Care Professionals | Hospital Environment

Brazil
National Institute of Allergy and Infectious Diseases...
Eunice Kennedy Shriver National Institute of Child Health and Human Development... and other collaborators

Recruiting

Study of a Single Dose of Pretomanid Added to an Optimized Background Regimen in Children With Rifampicin-Resistant Tuberculosis

Tuberculosis | Rifampicin Resistant Tuberculosis

Brazil, India, South Africa, Tanzania, Thailand
National Institute of Allergy and Infectious Diseases...
Eunice Kennedy Shriver National Institute of Child Health and Human Development... and other collaborators

Recruiting

Protecting Households On Exposure to Newly Diagnosed Index Multidrug-Resistant Tuberculosis Patients (PHOENIx MDR-TB)

Tuberculosis, MDR

Haiti, Tanzania, Thailand, Botswana, Brazil, India, Kenya, Peru, Philippines, South Africa, Uganda, Zimbabwe, Vietnam
National Institute of Allergy and Infectious Diseases...
Bristol-Myers Squibb

Completed

Safety and Effectiveness of a Three-Drug Combination Treatment for Recently Infected or Converted HIV Patients

HIV Infections

United States, Brazil
AIDS Clinical Trials Group
National Institute of Allergy and Infectious Diseases (NIAID)

Completed

Pharmacokinetic Study to Evaluate Double-Dose Levonorgestrel Emergency Contraception in Combination With Efavirenz-Based Antiretroviral Therapy or Rifampicin-Containing Anti-Tuberculosis Therapy

HIV Infections | Tuberculosis

United States, South Africa, Malawi, Brazil, Kenya, Thailand, Botswana
University of Miami
Oswaldo Cruz Foundation

Terminated

Pharmacokinetic Study of Super-boosted Lopinavir/Ritonavir Given With Rifampin

Tuberculosis | AIDS

Brazil
Evandro Chagas National Institute of Infectious...
Valdiléa Veloso dos Santos, Ph.D.; Beatriz Grinzstejn, MD, PhD; Brenda Hoagland... and other collaborators

Completed

Seroincidence Study Among Men Who Have Sex With Men and Transgender Women - The ImPrEP Seroincidence Study (Seroincidence)

HIV Infections | Risk Behavior | HIV Seropositivity | Risk Reduction | STD | HIV Infection Primary | Risky Health Behavior

Brazil
Global Alliance for TB Drug Development

Completed

Trial to Evaluate the Efficacy, Safety and Tolerability of BPaMZ in Drug-Sensitive (DS-TB) Adult Patients and Drug-Resistant (DR-TB) Adult Patients

Tuberculosis | Tuberculosis, Pulmonary | Tuberculosis, Multidrug-Resistant | Tuberculosis, MDR | Drug-Resistant Tuberculosis

Tanzania, Georgia, Russian Federation, Brazil, Malaysia, Philippines, South Africa, Uganda
ANRS, Emerging Infectious Diseases
MSD France

Not yet recruiting

DORAvirine Versus DOlutegravir Based Antiretroviral Regimens in Treatment-naïve People Living With HIV-1 Infection (ELDORADO)

HIV-1-infection

Brazil, Cambodia, Cameroon, Côte D'Ivoire, France, Mozambique
New York State Psychiatric Institute
National Institute of Mental Health (NIMH)

Completed

Testing an HIV Prevention Intervention for Psychiatric Patients in Brazil

HIV Infections | HIV Infection

Brazil
Janssen Infectious Diseases BVBA

Withdrawn

A Study to Evaluate the Efficacy and Safety of TMC207 in Patients With Pulmonary Infection With Multi-drug Resistant Mycobacterium Tuberculosis

Multi-drug Resistant Tuberculosis

China, Ukraine, Taiwan, Korea, Republic of, Peru, Brazil, Estonia, Latvia, Philippines, Russian Federation, South Africa, Thailand, Turkey, Georgia, Mexico, Cambodia, Ethiopia
Wyeth is now a wholly owned subsidiary of Pfizer

Completed

A Third-Party Blinded, Placebo Controlled Comparative Study of AS-101 Administered Intravenously in HIV Positive Patients With Advanced Disease

HIV Infections

Brazil
Hospital de Clinicas de Porto Alegre
Coordenação de Aperfeiçoamento de Pessoal de Nível Superior.

Completed

Folinic Acid and Vascular Reactivity in HIV

Human Immunodeficiency Virus (HIV) Infection

Brazil
Johns Hopkins University

Completed

Moxifloxacin As Part of a Multi-Drug Regimen For Tuberculosis

Tuberculosis

Brazil
University Medical Center Groningen

Unknown

Feasibility of Centralized Therapeutic Drug Monitoring of Fluoroquinolones in Multi-Drug Resistant Tuberculosis Patients (PERFECT)

Tuberculosis, Multidrug-Resistant

Sweden, United Kingdom, Australia, Belarus, Brazil, Greece, Italy, Latvia, Mexico, Netherlands, Portugal, South Africa, Tanzania

Clinical Trials on HIV and Tuberculosis Co-infection in Brazil

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