Clinical Trials on Health Technology in United Kingdom

Total 32109 results

Pfizer

Completed

A Study to Assess Safety, Tolerability and Pharmacokinetics of Ceftaroline in Healthy Subjects

Healthy Volunteers

United Kingdom
Genentech, Inc.

Completed

Study to Investigate the Effect of Formulation and Food on the Pharmacokinetics of GDC-0810

Healthy Volunteer

United Kingdom
MedImmune LLC

Completed

A Study to Assess the Safety of MEDI7836 in Healthy Adults.

Healthy Adults

United Kingdom
Egalet Ltd

Completed

Tolerability, Safety and Pharmacokinetics of Four Formulations of Ketorolac Tromethamine in Healthy Volunteers

Healthy Volunteers

United Kingdom
Katarina Kos
University of Exeter

Terminated

Incretin and KATP Channels

Healthy Subjects

United Kingdom
Hoffmann-La Roche

Completed

A Study of RO5186582 Treatment on Cytochrome P450 (CYP) 3A4 Activity in Healthy Participants

Healthy Volunteer

United Kingdom
Hoffmann-La Roche

Completed

A Bioavailability and Pharmacokinetic Study of Subcutaneous and Intravenous RO6811135 in Healthy Volunteers

Healthy Volunteer

United Kingdom
Takeda

Completed

TAK-385 Phase I Absorption, Distribution, Metabolism, Excretion and Absolute Bioavailability Study

Healthy Volunteers

United Kingdom
Actelion

Completed

A Study to Assess the Safety and Pharmacokinetics of Lucerastat (OGT 923) in Healthy Subjects

Healthy Subjects

United Kingdom
Actelion

Completed

A Study to Assess the Safety, Tolerability and Pharmacokinetics of Lucerastat (CDP923) After Multiple Dosing in Healthy Subjects

Healthy Subjects

United Kingdom
AstraZeneca

Completed

To Assess Safety, Tolerability and Pharmacodynamics of Intravenous MEDI8111 After Single Ascending Doses.

Healthy Subjects

United Kingdom
Astellas Pharma Europe B.V.

Completed

A Study to Assess the Effects of Single Ascending Doses of ASP1707 in Healthy Young Japanese Male Subjects

Healthy Subjects

United Kingdom
LEO Pharma

Completed

LEO 32731 - A Study in Healthy Male Subjects

Healthy Subjects

United Kingdom
ProtAffin Biotechnologie AG

Terminated

A Phase 1, First in Human Study to Investigate the Safety and Tolerability of PA401

Healthy Volunteers

United Kingdom
AstraZeneca

Terminated

Double-blind Placebo-controlled 2-part Study Assessing the Safety, Tolerability and PK of AZD1386 in Healthy Volunteers

Healthy Volunteers

United Kingdom
AstraZeneca

Terminated

Assess Safety, Tolerability and Pharmacokinetic (PK) of AZD1704 in Healthy Japanese Male and Non-Fertile Female Volunteers

Healthy Volunteers

United Kingdom
Light Chain Bioscience - Novimmune SA

Completed

First in Human Study of NI-0701 in Healthy Volunteers

Healthy Volunteers

United Kingdom
AnaMar AB

Terminated

AMAP102 - Safety, Tolerability and Pharmacokinetics in Healthy Subjects

Healthy Volunteers

United Kingdom
Institute of Child Health

Unknown

Feeding Bottle Design, Milk Intake and Infant Growth

Healthy Infants

United Kingdom
University of Leicester
Medical Research Council; University Hospitals, Leicester; Loughborough University and other collaborators

Completed

Exhaled Breath Metabolomic Biomarkers in the Acutely Breathless Patient (EMBER)

Heart Failure | Healthy | Asthma | COPD | Community-acquired Pneumonia | Breathlessness

United Kingdom
Incyte Corporation

Active, not recruiting

A Study Assessing the Mass Balance, Pharmacokinetics, and Metabolite Profiles of a Single Oral Dose of [14C]INCB099280 in Healthy Male Participants

Healthy Participants

United Kingdom
University of Exeter
The University of Queensland

Completed

Microalgae as an Alternative Protein Source in Human Nutrition. (MAPS)

Nutrition, Healthy

United Kingdom
Imperial College London

Completed

Minimally Invasive Sensing of Beta-lactam Antibiotics (MISBL)

Healthy Volunteers

United Kingdom
King's College London

Completed

The Role of Gut Microbiome on Cardiovascular Health Benefits of Dietary Lignans (CardioFlax Study).

Healthy Volunteers

United Kingdom
University College, London

Completed

Stimulating Compassion UsingTranscutaneous Vagus Nerve Stimulation

Healthy Volunteers

United Kingdom
Biogen

Completed

Study of BIIB091 Formulations in Healthy Participants

Healthy Volunteers

United Kingdom
Genentech, Inc.

Completed

Study to Investigate the Absorption, Metabolism, and Excretion of [14C]-GDC-9545 Following a Single Oral Dose (Part 1) and to Evaluate the Absolute and Relative Bioavailability of Oral Capsule Formulations of GDC-9545 (Part 2) in Healthy Female Subjects of Non-Childbearing Potential

Healthy Volunteers

United Kingdom
Daiichi Sankyo, Inc.
Quotient Sciences

Completed

A Study to Determine the Absolute Oral Bioavailability of Quizartinib Using a Radiolabeled Microtracer in Healthy Subjects

Healthy Subjects

United Kingdom
Ipsen

Completed

A Comparative Study to Evaluate the Effects and Mechanism of Action of Dysport®, Botox® and Xeomin® in the Extensor Digitorum Brevis Model in Healthy Adult Male Participants

Healthy Participants

United Kingdom
AstraZeneca
Parexel

Completed

A Study to Assess the Pharmacokinetics of AZD4831 When Administered Alone and in Combination With Itraconazole

Healthy Volunteers

United Kingdom
H. Lundbeck A/S

Completed

A Study Investigating Lu AG06466 in Healthy Men

Healthy Volunteers

United Kingdom
AstraZeneca

Completed

Study to Assess the Effect of AZD4831 on the Pharmacokinetics (Drug Behavior in the Body) of Midazolam

Healthy Volunteers

United Kingdom
Spero Therapeutics
United States Department of Defense

Completed

Study to Assess the Intrapulmonary Pharmacokinetics of SPR206 in Healthy Volunteers

Healthy Volunteers

United Kingdom
Heptares Therapeutics Limited

Completed

Comparison of Blood Levels of HTL0016878 From an Oral Capsule and an Oral Solution

Healthy Subjects

United Kingdom
GlaxoSmithKline

Completed

Safety, Tolerability, Pharmacokinetics, Pharmacodynamics of GSK2330811 in Healthy Japanese Participants

Healthy Volunteers

United Kingdom
Heptares Therapeutics Limited

Completed

Measurement of HTL0016878 in Cerebrospinal Fluid

Healthy Subjects

United Kingdom
GlaxoSmithKline

Completed

Safety, Tolerability, Pharmacokinetics (PK) and Pharmacodynamics (PD) of GSK2831781 After an Intravenous (IV) Dose in Healthy Japanese and Caucasian Subjects, and a Subcutaneous (SC) Dose in Healthy Caucasian Subjects

Healthy Volunteers

United Kingdom
MedDay Pharmaceuticals SA
Quotient Sciences

Completed

Mass Balance Recovery, Metabolite Profile and Metabolite Identification of [14C]-MD1003 in Healthy Male Subjects

Healthy Volunteers

United Kingdom
Ixchelsis Limited

Completed

Relative Bioavailability and Food Effect Study of IX-01 Capsules in Healthy Men

Healthy Participants

United Kingdom
Affibody
Parexel

Terminated

A Study to Investigate the Safety, Tolerability and Pharmacokinetics of ABY-039

Healthy Volunteers

United Kingdom
AstraZeneca
Quotient Sciences

Completed

AZD4635 Relative Bioavailability Study (Rel Bio)

Healthy Volunteers

United Kingdom
King's College London

Unknown

The Relationship Between Dual-task Gait Performance, Physical Activity Levels, Sleep and Aging in Healthy Adults

Healthy | Adults

United Kingdom
Genentech, Inc.

Completed

Effect of Food, Rabeprazole, Methotrexate and Formulation on the Pharmacokinetics (PK) of GDC-0853 and the Effect of GDC-0853 on the PK of Methotrexate in Healthy Subjects (QCL117578)

Healthy Volunteer

United Kingdom
Celgene

Completed

A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Single and Multiple Doses of CC-99677 in Healthy Adult Subjects

Healthy Volunteer

United Kingdom
Helsinn Healthcare SA
Quotient Sciences

Completed

A Study In Healthy Male Volunteers Designed To Investigate How A Radiolabelled Medicine Is Broken Down And Removed From The Body

Healthy Subjects

United Kingdom
Imperial College London

Completed

Effect of Broccoli Sprout on Blood Levels of Sulforaphane to Reduce Responsiveness of Immune System

Healthy Volunteers

United Kingdom
Quantum Genomics SA
Quotient Sciences

Completed

Evaluation of the PK Profile of Firibastat Following Administration of Firibastat Prototype Tablet Formulations

Healthy Males

United Kingdom
ORIC Pharmaceuticals

Completed

Single and Multiple Dose Study of ORIC-101 in Adult Healthy Subjects

Healthy Volunteers

United Kingdom
Regeneron Pharmaceuticals

Completed

Study of the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of REGN3918 in Healthy Volunteers

Healthy Volunteers

United Kingdom
Idorsia Pharmaceuticals Ltd.

Terminated

A Study to Evaluate if AC-084 is Safe, Its Fate in the Body as Well as Its Potential Effects on the Body in Healthy Subjects

Healthy Subjects

United Kingdom

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