Clinical Trials on Healthy, Hepatic Insufficiency in United Kingdom

Total 12967 results

Celgene

Completed

A Single Dose Oral Excretion Balance Study of [14C]-RPC1063 in Healthy Male Adults

Healthy Volunteers

United Kingdom
Hoffmann-La Roche

Completed

A Study of Aleglitazar in Combination With Oral Contraceptive Healthy Volunteers

Healthy Volunteer

United Kingdom
Hoffmann-La Roche

Completed

A Study of the Effect of RG1662 on Metformin in Healthy Volunteers

Healthy Volunteer

United Kingdom
Astellas Pharma Europe B.V.

Completed

A Combined Single and Multiple Ascending Dose Study of ASP6858 in Healthy Subjects

Healthy Volunteers

United Kingdom
Genentech, Inc.

Completed

A Safety, Tolerability, and Pharmacokinetic Study of GDC-3280 in Healthy Participants

Healthy Volunteer

United Kingdom
Ardelyx

Completed

AZD1722 Open Label, Absorption Distribution Metabolism and Excretion Study

Healthy Volunteers

United Kingdom
Astellas Pharma Europe B.V.

Completed

A Study to Investigate the Effect of Oral Doses of Pilocarpine on Salivary Secretion and Static Pupillometry in Healthy Subjects

Healthy Subjects

United Kingdom
Medicines for Malaria Venture

Completed

A Comparison of the Bioavailability of OZ439 When Delivered Directly to the Small Intestine, or Via the Oral Route

Healthy Volunteers

United Kingdom
UCB Celltech
Parexel

Completed

Study to Assess the Safety, Tolerability, Pharmacokinetic and Pharmacodynamic Profiles of UCB5857 in Healthy Subjects

Healthy Volunteers

United Kingdom
University of Manchester

Completed

Sunlight Exposure and Vitamin D Status of Children of South Asian Ethnicity Living in the UK

Healthy Volunteers

United Kingdom
H. Lundbeck A/S

Completed

Study Comparing the Gastro-intestinal Tolerability and Absorption Profile of Vortioxetine After Administration of Modified-release Formulations and Immediate-release Formulation in Healthy Women

Healthy Women

United Kingdom
Janssen Cilag N.V./S.A.

Completed

A Study to Investigate the Safety, Tolerability, and Pharmacokinetics of JNJ-38877618 in Healthy Male Participants

Healthy Volunteers

United Kingdom
Eli Lilly and Company

Completed

The Effects of Urinary pH Changes on an Investigational Compound in Healthy Subjects

Healthy Subjects

United Kingdom
Bristol-Myers Squibb

Completed

Comparability DE vs CD-CHO1

Healthy Subjects

United Kingdom
Incyte Corporation

Completed

A Study Assessing the Mass Balance, Pharmacokinetics, and Metabolite Profiles of a Single Oral Dose of [14C]INCB099280 in Healthy Male Participants

Healthy Participants

United Kingdom
University of Exeter
The University of Queensland

Completed

Microalgae as an Alternative Protein Source in Human Nutrition. (MAPS)

Nutrition, Healthy

United Kingdom
Imperial College London

Completed

Minimally Invasive Sensing of Beta-lactam Antibiotics (MISBL)

Healthy Volunteers

United Kingdom
King's College London

Completed

The Role of Gut Microbiome on Cardiovascular Health Benefits of Dietary Lignans (CardioFlax Study).

Healthy Volunteers

United Kingdom
University College, London

Completed

Stimulating Compassion UsingTranscutaneous Vagus Nerve Stimulation

Healthy Volunteers

United Kingdom
Biogen

Completed

Study of BIIB091 Formulations in Healthy Participants

Healthy Volunteers

United Kingdom
Genentech, Inc.

Completed

Study to Investigate the Absorption, Metabolism, and Excretion of [14C]-GDC-9545 Following a Single Oral Dose (Part 1) and to Evaluate the Absolute and Relative Bioavailability of Oral Capsule Formulations of GDC-9545 (Part 2) in Healthy Female Subjects of Non-Childbearing Potential

Healthy Volunteers

United Kingdom
Daiichi Sankyo, Inc.
Quotient Sciences

Completed

A Study to Determine the Absolute Oral Bioavailability of Quizartinib Using a Radiolabeled Microtracer in Healthy Subjects

Healthy Subjects

United Kingdom
Ipsen

Completed

A Comparative Study to Evaluate the Effects and Mechanism of Action of Dysport®, Botox® and Xeomin® in the Extensor Digitorum Brevis Model in Healthy Adult Male Participants

Healthy Participants

United Kingdom
AstraZeneca
Parexel

Completed

A Study to Assess the Pharmacokinetics of AZD4831 When Administered Alone and in Combination With Itraconazole

Healthy Volunteers

United Kingdom
H. Lundbeck A/S

Completed

A Study Investigating Lu AG06466 in Healthy Men

Healthy Volunteers

United Kingdom
AstraZeneca

Completed

Study to Assess the Effect of AZD4831 on the Pharmacokinetics (Drug Behavior in the Body) of Midazolam

Healthy Volunteers

United Kingdom
Spero Therapeutics
United States Department of Defense

Completed

Study to Assess the Intrapulmonary Pharmacokinetics of SPR206 in Healthy Volunteers

Healthy Volunteers

United Kingdom
Heptares Therapeutics Limited

Completed

Comparison of Blood Levels of HTL0016878 From an Oral Capsule and an Oral Solution

Healthy Subjects

United Kingdom
GlaxoSmithKline

Completed

Safety, Tolerability, Pharmacokinetics, Pharmacodynamics of GSK2330811 in Healthy Japanese Participants

Healthy Volunteers

United Kingdom
Heptares Therapeutics Limited

Completed

Measurement of HTL0016878 in Cerebrospinal Fluid

Healthy Subjects

United Kingdom
GlaxoSmithKline

Completed

Safety, Tolerability, Pharmacokinetics (PK) and Pharmacodynamics (PD) of GSK2831781 After an Intravenous (IV) Dose in Healthy Japanese and Caucasian Subjects, and a Subcutaneous (SC) Dose in Healthy Caucasian Subjects

Healthy Volunteers

United Kingdom
MedDay Pharmaceuticals SA
Quotient Sciences

Completed

Mass Balance Recovery, Metabolite Profile and Metabolite Identification of [14C]-MD1003 in Healthy Male Subjects

Healthy Volunteers

United Kingdom
Ixchelsis Limited

Completed

Relative Bioavailability and Food Effect Study of IX-01 Capsules in Healthy Men

Healthy Participants

United Kingdom
Affibody
Parexel

Terminated

A Study to Investigate the Safety, Tolerability and Pharmacokinetics of ABY-039

Healthy Volunteers

United Kingdom
AstraZeneca
Quotient Sciences

Completed

AZD4635 Relative Bioavailability Study (Rel Bio)

Healthy Volunteers

United Kingdom
King's College London

Unknown

The Relationship Between Dual-task Gait Performance, Physical Activity Levels, Sleep and Aging in Healthy Adults

Healthy | Adults

United Kingdom
Genentech, Inc.

Completed

Effect of Food, Rabeprazole, Methotrexate and Formulation on the Pharmacokinetics (PK) of GDC-0853 and the Effect of GDC-0853 on the PK of Methotrexate in Healthy Subjects (QCL117578)

Healthy Volunteer

United Kingdom
Celgene

Completed

A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Single and Multiple Doses of CC-99677 in Healthy Adult Subjects

Healthy Volunteer

United Kingdom
Helsinn Healthcare SA
Quotient Sciences

Completed

A Study In Healthy Male Volunteers Designed To Investigate How A Radiolabelled Medicine Is Broken Down And Removed From The Body

Healthy Subjects

United Kingdom
Imperial College London

Completed

Effect of Broccoli Sprout on Blood Levels of Sulforaphane to Reduce Responsiveness of Immune System

Healthy Volunteers

United Kingdom
Quantum Genomics SA
Quotient Sciences

Completed

Evaluation of the PK Profile of Firibastat Following Administration of Firibastat Prototype Tablet Formulations

Healthy Males

United Kingdom
ORIC Pharmaceuticals

Completed

Single and Multiple Dose Study of ORIC-101 in Adult Healthy Subjects

Healthy Volunteers

United Kingdom
Regeneron Pharmaceuticals

Completed

Study of the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of REGN3918 in Healthy Volunteers

Healthy Volunteers

United Kingdom
Idorsia Pharmaceuticals Ltd.

Terminated

A Study to Evaluate if AC-084 is Safe, Its Fate in the Body as Well as Its Potential Effects on the Body in Healthy Subjects

Healthy Subjects

United Kingdom
Debiopharm International SA

Completed

A Study to Investigate the Effect of Itraconazole on the Pharmacokinetics of Debio 1450 in Healthy Subjects

Healthy Participants

United Kingdom
Egalet Ltd

Completed

Open Label Study to Assess the Pharmacokinetics of Intranasal Ketorolac Tromethamine Following Fluticasone Propionate in Healthy Subjects

Healthy Subjects

United Kingdom
Hoffmann-La Roche

Completed

Basmisanil Positron Emission Tomography Study in Japanese Volunteers

Healthy Volunteer

United Kingdom
Guy's and St Thomas' NHS Foundation Trust
B&D Electromedical

Completed

EIT Study With Healthy Patients (EIT Step 1)

Healthy Participants

United Kingdom
Ixchelsis Limited

Completed

A Study of Multiple Oral Doses of IX-01 in Healthy Male Subjects

Healthy Volunteers

United Kingdom
Hoffmann-La Roche

Completed

A Study to Investigate the Effects of Rifampicin on the Pharmacokinetics of Aleglitazar in Healthy Volunteers

Healthy Volunteer

United Kingdom

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