Clinical Trials on Healthy Volunteer Smokers in United Kingdom

Total 8763 results

Helsinn Healthcare SA
Celerion

Completed

Study to Evaluate the Food Effect of Single-dose Bioavailability of Pracinostat in Healthy Adult Subjects (HVFE)

Healthy Volunteers | Non-smokers | Moderate to Heavy Smokers

United States
Helsinn Healthcare SA

Completed

Evaluate the Effects of Itraconazole and Ciprofloxacin on Single-Dose PK of Pracinostat in Healthy Nonsmoking Subjects

Healthy Volunteers | Non-smokers

United States
Imperial College London
GlaxoSmithKline

Withdrawn

Biomarkers of iNOS Activity in COPD, Asthma, Healthy Control

Healthy Smokers | Healthy Non-smokers | Patients With Mild Asthma | Patints With COPD (GOLD II)

United Kingdom
Imperial College London
AstraZeneca

Withdrawn

Effect of Symbicort on HAT and HDAC in Sputum Macrophages of COPD

Chronic Obstructive Pulmonary Disease (COPD) | Age Matched Healthy Volunteers (Non-smokers)

United Kingdom
Mitsubishi Tanabe Pharma America Inc.

Completed

Mass Balance Study With MT-7117 (MT-7117 MB)

Healthy Volunteer

United Kingdom
Imperial College London
AstraZeneca

Withdrawn

Markers for Chronic Obstructive Pulmonary Disease (COPD)

COPD Patients | Current Smokers | Healthy Non-smokers

United Kingdom
Genentech, Inc.

Completed

Effect of Food, Rabeprazole, Methotrexate and Formulation on the Pharmacokinetics (PK) of GDC-0853 and the Effect of GDC-0853 on the PK of Methotrexate in Healthy Subjects (QCL117578)

Healthy Volunteer

United Kingdom
Celgene

Completed

A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Single and Multiple Doses of CC-99677 in Healthy Adult Subjects

Healthy Volunteer

United Kingdom
Hoffmann-La Roche

Completed

Basmisanil Positron Emission Tomography Study in Japanese Volunteers

Healthy Volunteer

United Kingdom
Hoffmann-La Roche

Completed

A Study to Investigate the Effects of Rifampicin on the Pharmacokinetics of Aleglitazar in Healthy Volunteers

Healthy Volunteer

United Kingdom
Hoffmann-La Roche

Completed

A Pharmacokinetics Study of Aleglitazar in Combination With Digoxin in Healthy Volunteers

Healthy Volunteer

United Kingdom
Hoffmann-La Roche

Completed

A Study of RO6926496 in Healthy Volunteers

Healthy Volunteer

United Kingdom
Hoffmann-La Roche

Completed

A Pharmacodynamic Study to Evaluate Neutrophil Distribution Kinetics and Function Following Single-Dose RoActemra/Actemra (Tocilizumab) in Healthy Volunteers

Healthy Volunteer

United Kingdom
AstraZeneca

Completed

Study to Investigate the Safety, Tolerability and Pharmacokinetics of Single Doses of AZD8566.

Healthy Volunteer

United Kingdom
Emalex Biosciences Inc.
Covance

Completed

Study of the Absorption, Metabolism, and Excretion of [14C]-Ecopipam in Healthy Male Subjects

Healthy Volunteer

United Kingdom
University of Edinburgh
Royal College of Surgeons of Edinburgh; Translational Medicine Research Collaboration

Completed

Cell Tracking Using Superparamagnetic Particles of Iron Oxide (SPIO) and Magnetic Resonance Imaging (MRI) - A Pilot Study

Healthy Volunteer

United Kingdom
PCI Biotech AS

Completed

Study to Assess Safety, Tolerability and Immune Response of Fimaporfin-induced Photochemical Internalisation of Antigen/Adjuvant

Healthy Volunteer

United Kingdom
Genentech, Inc.

Withdrawn

A Study to Assess the Relative Bioavailability And Food Effect of a Tablet Formulation of GDC-0276 in Healthy Participants

Healthy Volunteer

United Kingdom
Genentech, Inc.

Completed

Study to Investigate the Effect of Formulation and Food on the Pharmacokinetics of GDC-0810

Healthy Volunteer

United Kingdom
Hoffmann-La Roche

Completed

A Study of RO5186582 Treatment on Cytochrome P450 (CYP) 3A4 Activity in Healthy Participants

Healthy Volunteer

United Kingdom
Hoffmann-La Roche

Completed

A Bioavailability and Pharmacokinetic Study of Subcutaneous and Intravenous RO6811135 in Healthy Volunteers

Healthy Volunteer

United Kingdom
Moleculin Biotech, Inc.

Completed

Study to Assess the Safety and Pharmacokinetics of WP1122 in Healthy Volunteers

Healthy Volunteer

United Kingdom
AstraZeneca
Quotient Sciences

Completed

A Study to Investigate the Absolute Bioavailability, Absorption, Metabolism, Distribution and Excretion of [14C]AZD5363 (Capivasertib)

Healthy Volunteer

United Kingdom
Celgene

Completed

A Study to Evaluate Potential Cytochrome P450 and Transporter Protein Interactions With CC-99677

Healthy Volunteer

United Kingdom
MedImmune LLC

Completed

Phase 1 Single-ascending Dose Study to Evaluate Safety and Tolerability of MEDI4920 in Healthy Adults

Healthy Volunteer

United Kingdom
Aquinox Pharmaceuticals (Canada) Inc.
Quotient Clinical

Completed

Phase 1 Absorption Distribution Metabolism and Excretion of AQX-1125 (ADME)

Healthy Volunteer

United Kingdom
Hoffmann-La Roche

Completed

A Study of Aleglitazar in Combination With Oral Contraceptive Healthy Volunteers

Healthy Volunteer

United Kingdom
Hoffmann-La Roche

Completed

A Study of the Effect of RG1662 on Metformin in Healthy Volunteers

Healthy Volunteer

United Kingdom
Genentech, Inc.

Completed

A Safety, Tolerability, and Pharmacokinetic Study of GDC-3280 in Healthy Participants

Healthy Volunteer

United Kingdom
Roswell Park Cancer Institute
National Institute on Drug Abuse (NIDA); National Cancer Institute (NCI)

Completed

Nicotine Delivery From Novel Non-Tobacco Electronic System in Smokers (ENDS)

Current Smoker | Healthy Subject | Cigarette Smoker

United States
GlaxoSmithKline

Completed

An Evaluation of Two Novel Nasal Strip Prototypes on Nasal Patency

Healthy Volunteer

United Kingdom
Mitsubishi Tanabe Pharma America Inc.

Completed

Mass Balance Study With MT-8554 (MT-8554 MB)

Healthy Volunteer

United Kingdom
Aegerion Pharmaceuticals, Inc.
Richmond Pharmacology Limited

Completed

Phase I Study of the Safety, Tolerability, PK & PD of Lomitapide in Japanese and Caucasian Subjects With Elevated LDL-C

Healthy Volunteer

United Kingdom
AstraZeneca

Completed

AZD8566 Food Effect/Microtracer Study

Healthy Volunteer Study

United Kingdom
Mitsubishi Tanabe Pharma America Inc.

Completed

Definitive QT Study With MT-8554 (MT-8554 DQT)

Healthy Volunteer

United Kingdom
AstraZeneca

Completed

AZD2423 Single Ascending Dose Study in Healthy Japanese Subjects (JSAD)

Healthy Volunteer

United Kingdom
University of Oxford

Completed

The Effect of D-cycloserine on Emotional Processing

Healthy Volunteer | Cycloserine

United Kingdom
Exicure, Inc.

Completed

A Study of AST-008 in Healthy Subjects

Healthy Volunteer Study

United Kingdom
Reckitt Benckiser Healthcare (UK) Limited

Completed

Ibuprofen Suspension Bioequivalence Study

Healthy Volunteer Study

United Kingdom
BenevolentAI Bio

Completed

Study Investigating the Safety, Tolerability, PK and Food Effect of BEN8744.

Healthy Volunteer Study

United Kingdom
GlaxoSmithKline

Completed

At What Time Therapeutic Plasma Concentrations of Paracetamol Are Achieved in Two Marketed Formulations

Healthy Volunteer

United Kingdom
Simbec Research

Completed

A Study Comparing Three Formulations of Ibuprofen in Healthy Subjects

Healthy Volunteer Study

United Kingdom
Trident Pharmaceuticals Inc

Completed

Safety Study of Four Doses of the Study Drug, HF1020 in Healthy Volunteers

Healthy Volunteer Study

United Kingdom
AstraZeneca
Parexel

Completed

A Study to Assess the Effect of Fluvoxamine and Smoking on Pharmacokinetics ( the Movement of Drugs Within the Body) of AZD4635 in Healthy Volunteers

Healthy Volunteer/DDI Study

United Kingdom
Denovo Biopharma LLC

Completed

A Study of LY2140023 in Healthy Participants

Healthy Volunteer Study

United Kingdom
Imperial College London

Completed

Minimally Invasive Sensing of Beta-lactam Antibiotics (MISBL)

Healthy Volunteers

United Kingdom
King's College London

Completed

The Role of Gut Microbiome on Cardiovascular Health Benefits of Dietary Lignans (CardioFlax Study).

Healthy Volunteers

United Kingdom
University College, London

Completed

Stimulating Compassion UsingTranscutaneous Vagus Nerve Stimulation

Healthy Volunteers

United Kingdom
Biogen

Completed

Study of BIIB091 Formulations in Healthy Participants

Healthy Volunteers

United Kingdom
Genentech, Inc.

Completed

Study to Investigate the Absorption, Metabolism, and Excretion of [14C]-GDC-9545 Following a Single Oral Dose (Part 1) and to Evaluate the Absolute and Relative Bioavailability of Oral Capsule Formulations of GDC-9545 (Part 2) in Healthy Female Subjects of Non-Childbearing Potential

Healthy Volunteers

United Kingdom

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