Clinical Trials on Healthy Volunteers Pharmacokinetic Study in United Kingdom

Total 1807 results

Shionogi

Completed

Effect of Administration of Itraconazole on the Pharmacokinetics of S-309309 in Healthy Participants

Obesity | Healthy Volunteers

United States
Galmed Pharmaceuticals Ltd
Kramer Consulting, LLC; WCCT Global; Diamond Pharma Services Regulatory Affairs... and other collaborators

Completed

Pharmacokinetics of Single and Multiple Escalating Doses of Aramchol Administered Under Fed Conditions in Healthy Chinese Volunteers

Healthy Volunteers

United States
Janssen Research & Development, LLC

Completed

A Bioequivalence Study of the Fixed Dose Combination Tablets of Canagliflozin and Metformin Extended Release (XR) With Respect to the Individual Components

Healthy Volunteers

United States
Northwell Health

Terminated

A Pharmacokinetic Study to Compare the Dosing of Valproic Acid in Subjects With Different Body Weights

Healthy | Obesity | Pharmacokinetics

United States
Hoffmann-La Roche

Completed

A Study to Assess the Impact of Speed and Site of Subcutaneous Injection on Pain, Tolerability, Safety, and Pharmacokinetics of Gantenerumab in Healthy Participants

Healthy Volunteer

United States
Brown University
National Institute of Mental Health (NIMH)

Recruiting

Cognitive Control & the Functional Organization of the Frontal Cortex

Healthy Volunteers | Executive Function | Multitasking Behavior and Neural Representations Associated With Multitasking Ability

United States
Respiree Pte Ltd

Completed

Accuracy of Pulse Oximeters With Profound Hypoxia

Healthy Volunteers

United States
Genentech, Inc.

Completed

A Study to Investigate the Relative Bioavailability of Entrectinib Capsule Formulations F1 and F06 Under Fed Conditions in Healthy Participants

Healthy Volunteers

United States
Janssen Research & Development, LLC

Completed

Multiple Dose Pharmacokinetics of Canagliflozin/Metformin 150/1,000 mg Fixed Dose Combination

Healthy Volunteers

United States
Sanofi

Completed

A Food Effect and Relative Bioavailability Study of Rilzabrutinib in Healthy Participants

Healthy Volunteers | Autoimmune Disorder

United States
Pfizer

Completed

Effect Of Hepatic Impairment on the Pharmacokinetics, Safety and Tolerability of PF-06865571 In Subjects With Hepatic Impairment and in Healthy Subjects

Healthy Volunteers | Hepatic Impairment

United States
Jenny Tong, MD, MPH

Withdrawn

Effect of Ghrelin on Decision-Making

Obesity | Healthy Volunteers

United States
Mespere Lifesciences Inc.

Completed

Accuracy of Oximeters With Hypoxia and Methemoglobin or Carboxyhemoglobin

Healthy Volunteers

United States
Astellas Pharma Inc

Completed

A Single Oral Dose Study to Compare the Bioavailability Between Two Different Tablet Formulations and Assess if There is a Food Effect With the New Formulation

Healthy Subjects | Bioavailability of ASP015K | Pharmacokinetics of ASP015K

United States
Winston Laboratories

Completed

Civamide Patch Safety, Tolerability and PK Study

Healthy Volunteers

United States
AstraZeneca

Completed

AZD8683 Single Ascending Dose Study

Healthy Volunteers

United States
Mannkind Corporation

Completed

Comparison of 30 Units of TI (Technosphere® Insulin) Prepared With Insulin From Two Different Suppliers

Healthy Volunteers

United States
AbbVie

Completed

A Study to Assess the Adverse Events and How Oral ABBV-552 Capsules Moves Through the Body of Healthy Adult Japanese and Han Chinese Participants

Healthy Volunteers

United States
National Institute of Mental Health (NIMH)

Recruiting

Development of Magnetic Resonance Spectroscopic Imaging Techniques for Imaging Metabolites in Human Brain and Muscle

Healthy Volunteer | Brain Mapping

United States
GlaxoSmithKline

Completed

A Study to Evaluate the Safety and Tolerability, Pharmacokinetics (PK) and Pharmacodynamics (PD) of Melrilimab (GSK3772847) in Healthy Participants

Asthma | Healthy Volunteers

United States
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Collection of Blood and Bone Marrow From Healthy Volunteers and Patients for Research Purposes

Bone Marrow Diseases | Healthy Volunteers

United States
National Human Genome Research Institute (NHGRI)

Completed

Are Genetic Counselors Screening for Adolescent Suicide Risk?

Healthy Volunteers

United States
MedImmune LLC

Completed

Phase 1, Single Dose Study to Evaluate Safety, Pharmacokinetics, and Pharmacodynamics of MEDI5884

Healthy Volunteers

United States
Bayer

Recruiting

A Study to Learn About How BAY2927088 Affects the Level of Dabigatran or Rosuvastatin in the Blood When These Drugs Are Taken Together in Healthy Participants

Healthy Volunteers | Advanced Non-small Cell Lung Cancer | EGFR Mutation | HER2 Mutation

United Kingdom
Mannkind Corporation

Completed

Compare the Same Dosage of Insulin Using a Combination of Cartridges, 30 Units as 2 Cartridges vs. 1 Cartridge

Healthy Volunteers

United States
Mannkind Corporation

Completed

Pharmacokinetic Study in Healthy Volunteers

Healthy Volunteers

United States
AstraZeneca
Parexel

Recruiting

A Placebo-controlled Safety and Tolerability Study of Intravenous (IV) and Subcutaneous (SC) AZD1163 in Healthy Volunteers

Healthy Volunteers

United States, Germany
Amgen

Completed

Effect of Denosumab on Cellular Biomarkers in the Human Breast

Healthy Volunteer, Female, Breast

United States
Hoffmann-La Roche

Completed

A Molecular and Functional Brain Imaging Study in Individuals With Down Syndrome and Healthy Controls Following Single Dose RG1662

Healthy Volunteer, Down Syndrome

United Kingdom
Hoffmann-La Roche

Completed

A Screening Study To Assess The Cognition Status in Healthy Volunteers

Healthy Volunteer

United States, Germany, Poland
Pfizer

Completed

CP-690,550 and Midazolam Drug-Drug Interaction Study

Healthy Volunteer

United States
National Institute of Mental Health (NIMH)

Recruiting

Neurobiology of Suicide

Depression | Healthy Volunteers

United States
Kyowa Kirin, Inc.
PPD

Completed

Study to Assess Bioequivalence and Adhesion Properties Between Two Granisetron Transdermal Patches.

Healthy Volunteers

United States
National Institute of Diabetes and Digestive and...

Completed

Acute Effects of Canagliflozin, a Sodium Glucose Co-Transporter 2 (SGLT2) Inhibitor on Bone Metabolism in Healthy Volunteers

Healthy Volunteers

United States
Ohio State University Comprehensive Cancer Center

Active, not recruiting

Black Raspberry Confection in Preventing Oral Cancer in Healthy Volunteers

Healthy Volunteers

United States
National Institutes of Health Clinical Center (CC)

Completed

Impact of Steady State Cobicistat and Darunavir/Cobicistat on the Pharmacokinetics and Pharmacodynamics of Oral Anticoagulants (Rivaroxaban, Apixaban) in Health Volunteers

Healthy Volunteers

United States
National Institutes of Health Clinical Center (CC)

Completed

Impact of Weekly Administration of Rifapentine and Isoniazid on Steady State Pharmacokinetics of Tenofovir Alafenamide in Healthy Volunteers (YODA)

Healthy Volunteers

United States
Novartis Pharmaceuticals

Completed

Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of TAP311 in Healthy Subjects and Dyslipidemic Patients

Dyslipidemia | Healthy Volunteers

United States
Rempex Pharmaceuticals (a wholly owned subsidiary...

Completed

Safety, Tolerability, Pharmacokinetics of Intravenous RPX2003 (Biapenem) in Healthy Adult Subjects

Bacterial Infections | Healthy Volunteers

United States
Cellivery Therapeutics, Inc.
Labcorp Corporation of America Holdings, Inc

Suspended

iCP-NI - Safety, Tolerability, Pharmacokinetic, and Immunogenicity Study in Healthy Male and Female Subjects

Healthy Volunteers

United States
Sanofi Pasteur, a Sanofi Company

Completed

Immunogenicity and Safety of a Quadrivalent Meningococcal Conjugate Vaccine in Infants and Toddlers When Administered Concomitantly With Routine Pediatric Vaccines in the United Kingdom (MET52)

Healthy Volunteers (Meningococcal Infection)

United Kingdom
National Institute of Neurological Disorders and...

Completed

Spaced Versus Massed Skill Learning

Healthy Volunteer

United States
National Institute of Allergy and Infectious Diseases...

Completed

Systems Analyses of the Immune Response to the Seasonal Influenza Vaccine

Healthy Volunteer

United States
Sanofi Pasteur, a Sanofi Company

Completed

Study to Assess the Safety and Immunogenicity of Monovalent mRNA NA Vaccine in Adult Participants 18 Years of Age and Older

Healthy Volunteers | Influenza Immunization

United States
AstraZeneca

Completed

Drug-Drug Interaction Study With AZD9291 and Omeprazole in Healthy Volunteers

Healthy Volunteer

United States
National Institute of Diabetes and Digestive and...

Recruiting

The Effects of Increasing Caloric Intake on Diet-Induced Thermogenesis and 24h Energy Expenditure

Obesity | Healthy Volunteers | Normal Physiology

United States
National Institute of Diabetes and Digestive and...

Completed

Thyroid Hormones Homeostasis and Energy Metabolism Changes During Stimulation of Endogenously Secreted Bile Acids (BAs)

Healthy Volunteers

United States
Eunice Kennedy Shriver National Institute of Child...

Completed

Bone Marrow Cell Engraftment of the Uterus and Genetic Studies of Reproductive Functioning

Endometriosis | Healthy Volunteers | Stem Cell Transplant

United States
Mirum Pharmaceuticals, Inc.

Completed

Study to Assess the Relative Potency of Multiple Oral Doses of LUM001 and SHP626 in Overweight and Obese Adults as Assessed by Fecal Bile Acid Excretion

Healthy Volunteers

United States
Gannex Pharma Co., Ltd.

Completed

Safety, Tolerability, and Pharmacokinetics of ASC43F, a Fixed Dose Combination Tablet in Healthy Subjects

Healthy Volunteer

United States

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