Clinical Trials on Heart Failure and Impaired Kidney Function in United States

Total 4021 results

AstraZeneca

Recruiting

Study to Evaluate the Effect of Balcinrenone/Dapagliflozin in Patients With Heart Failure and Impaired Kidney Function (BalanceD-HF)

Heart Failure and Impaired Kidney Function

Spain, France, Germany, Italy, United States, Argentina, Czechia, Vietnam, Peru, China, Philippines, Saudi Arabia, Australia, Austria, Canada, Japan, Malaysia, Poland, Taiwan, Thailand, Israel, Brazil, Finland, Greece, Mexico, United Kingdom and more
Amgen

Completed

Study to Evaluate the Safety, Tolerability and Pharmacokinetics of AMG 986 Administered Orally to Healthy Volunteers and Participants With Severely Impaired Renal Function

Heart Failure

United States
Genta Incorporated

Completed

Pharmacokinetic Study of Genasense in Subjects With Normal Renal Function, Mildly Impaired Renal Function, and Moderately Impaired Renal Function

Normal Renal Function | Mildly Impaired Renal Function | Moderately Impaired Renal Function

United States
NicOx

Completed

A Pharmacokinetics and Safety Study of Naproxcinod in Subjects With Impaired Renal Function (HCT3012-X-106)

Renal Failure

United States
Stealth BioTherapeutics Inc.

Completed

A Phase 1 Study Investigating the Safety and Pharmacokinetics of Repeat-dose Intravenous Infusion of MTP-131 in Subjects With Impaired Renal Function

Normal and Impaired Renal Function

United States
Solvay Pharmaceuticals
Quintiles, Inc.

Terminated

Study to Evaluate the Effect of SLV320 in Addition to Chronic Furosemide Treatment on Renal Function in Subjects With Congestive Heart Failure and Impaired Renal Function

Congestive Heart Failure

United States, Argentina, Belgium, Czech Republic, Former Serbia and Montenegro, Germany, Poland, Russian Federation, South Africa, Spain
Allergan

Completed

Study of Ulipristal Acetate in Female Patients With Moderately or Severely Impaired Renal Function, Compared With Matched Healthy Female Subjects

Renal Function

United States
Novartis Pharmaceuticals

Completed

Evaluation of Renal Function Impairment on the Pharmacokinetics of LEE011

Impaired Renal Function | Normal Renal Function

United States, Germany, Bulgaria, Czechia
NGM Biopharmaceuticals, Inc

Completed

Study of Aldafermin (NGM282) in Participants With Impaired Renal Function

Impaired Renal Function

United States
Shire

Completed

Study of SSP-004184 (FBS0701) in Healthy Adults and Elderly Subjects and in Subjects With Impaired Renal Function

Impaired Renal Function

United States
Eloxx Pharmaceuticals, Inc.
Syneos Health

Completed

A Study to Evaluate the Effects of Renal Impairment on the Pharmacokinetics of ELX-02

Impaired Renal Function

United States
Astellas Pharma Europe B.V.
FibroGen

Completed

A Phase 1 Study of Roxadustat in Subjects With Different Degrees of Renal Function

Impaired Renal Function | Normal Renal Function

Germany, United Kingdom
Bausch Health Americas, Inc.

Completed

Pharmacokinetics, Safety, and Tolerability of Methylnaltrexone (MNTX) in Subjects With Impaired Renal Function

Renal Impairment

United States
Gilead Sciences

Completed

Pharmacokinetics of Lanraplenib in Adults With Impaired Renal Function

Inflammatory Disease

United States, New Zealand, Germany
Exelixis

Completed

A Single-Dose Study to Assess the Pharmacokinetics of Cabozantinib (XL184) Capsules in Subjects With Impaired Renal Function

Healthy | Renal Impairment

United States
GlaxoSmithKline

Completed

A Phase I Topotecan Study in Subjects With Cancer and Impaired Renal Function

Solid Tumours

United States, Korea, Republic of, Netherlands
VA New York Harbor Healthcare System
Daxor Corporation

Completed

Blood Volume Analysis and Renal Outcomes in Hemodialysis

Kidney Failure | End Stage Renal Failure on Dialysis | Actual Impaired Fluid Volume

United States
Bayer

Completed

A Study to Evaluate the Pharmacokinetics (How it Moves Into, Through and Out From the Body) of a New Gadolinium-based Contrast Agent (GBCA) After Injection and How Safe it is in Participants With Normal and Impaired Renal Function

Contrast Enhancement in Magnetic Resonance Imaging

United States
Novartis Pharmaceuticals

Completed

Study of the Safety, Tolerability, and Pharmacokinetics of LHW090 in Patients With Moderately Impaired Renal Function (LHW090)

Chronic Kidney Disease (CKD)

Germany, United States
Gilead Sciences

Completed

Pharmacokinetics of Bictegravir in Adults With Normal and Impaired Renal Function

HIV

United States, New Zealand
Virginia Commonwealth University

Completed

Chronic Kidney Disease and Heart Failure With Preserved Ejection Fraction: The Role of Mitochondrial Dysfunction

Renal Insufficiency, Chronic | Heart Failure With Preserved Ejection Fraction

United States
Massachusetts General Hospital
Roche Diagnostics GmbH

Recruiting

Biomechanical Precision Medicine Registry for Patients With and Without Heart Failure (PREFER-HF)

Cardiovascular Risk Factor | Heart Failure With Reduced Ejection Fraction | Heart Failure With Normal Ejection Fraction | Heart Failure, Right Sided | Heart Failure With Mid Range Ejection Fraction

United States
Eisai Inc.

Completed

An Open-Label Study to Assess the Pharmacokinetics and Safety of HALAVEN in Subjects With Cancer Who Also Have Impaired Renal Function

Unspecified Adult Solid Tumor, Protocol Specific

United States
Yale University

Completed

Validation of the Gated Blood Pool SPECT: ERNA vs 3D Echo

Congestive Heart Failure | Ventricular Function, Left

United States
Milton S. Hershey Medical Center

Withdrawn

Wearable Remote Monitoring of Heart Rate and Respiratory Rate for Heart Failure

Heart Failure | Heart Failure With Reduced Ejection Fraction | Heart Failure With Preserved Ejection Fraction

United States
Milton S. Hershey Medical Center

Completed

Electronic S3 Prediction of Hospital Readmissions for HF Exacerbation

Heart Failure | Heart Failure With Reduced Ejection Fraction | Heart Failure With Preserved Ejection Fraction

United States
Yale University

Recruiting

Real-Time Monitoring of Heart Failure Across the Yale New Haven Health System (Yale-HF)

Heart Failure | Heart Failure With Reduced Ejection Fraction | Heart Failure With Preserved Ejection Fraction | Heart Failure NYHA Class IV

United States
Medical University of South Carolina

Completed

LYmphangiogenesis FacTors in Heart Failure States (LYFT-HF)

Heart Failure | Heart Failure With Reduced Ejection Fraction | Heart Failure With Normal Ejection Fraction

United States
Massachusetts General Hospital
National Heart, Lung, and Blood Institute (NHLBI); Beth Israel Deaconess Medical... and other collaborators

Active, not recruiting

Circulating RNAs in Acute Congestive Heart Failure (CRUCiAL)

Heart Failure With Reduced Ejection Fraction | Heart Failure With Normal Ejection Fraction | Acute Congestive Heart Failure

United States
VA Eastern Colorado Health Care System
National Institute on Aging (NIA)

Completed

Balance, Aerobic Capacity, Mobility and Strength in Patients Hospitalized for Heart Failure (BAMS-HF) Program (BAMS-HF)

Heart Failure | Heart Failure, Diastolic | Heart Failure, Systolic | Heart Failure With Reduced Ejection Fraction | Heart Failure With Preserved Ejection Fraction | Heart Failure; With Decompensation | Heart Failure，Congestive | Heart Failure Acute

United States
Boehringer Ingelheim

Completed

Pradaxa Study in Non-valvular Atrial Fibrillation Patients With Severely Impaired Renal Function

Atrial Fibrillation

United States
Medical College of Wisconsin
Advancing a Healthier Wisconsin

Recruiting

Pilot Study Lp299v Supplementation in Chronic Heart Failure

Heart Failure | Heart Failure, Diastolic | Heart Failure, Systolic | Heart Failure With Reduced Ejection Fraction | Heart Failure With Preserved Ejection Fraction

United States
Board of Trustees of Illinois State University
University of Colorado, Denver; Abbott; University of North Carolina, Greensboro and other collaborators

Recruiting

Consistently Assess Signs and Symptom of Heart Failure (CLASS-HF)

Heart Failure | Heart Failure With Reduced Ejection Fraction | Heart Failure With Preserved Ejection Fraction

United States
MediBeacon

Completed

Pharmacokinetics of MB-102 and Use of the Non-invasive Optical Renal Function Monitor (ORFM) Device in Subjects With Normal and Impaired Renal Function and a Range of Skin Color Types

Acute Kidney Injury

United States
Paris Translational Research Center for Organ Transplantation

Unknown

Trajectories of Glomerular Filtration Rate and Progression to End Stage Renal Disease After Kidney Transplantation (TRAJAKT)

Kidney Transplant Failure | Kidney Function Issue

United States, Belgium, Croatia, France
Novartis Pharmaceuticals

Terminated

A Dose-escalation Pharmacokinetic Study of Intravenous ASA404 in Adult Advanced Cancer Patients With Impaired Renal Function and Patients With Normal Renal Function

Metastatic Cancer

United States
University of Oklahoma

Withdrawn

Magnesphere for Autonomic Alteration

Hart Failure With Reduced Ejection Fraction

United States
Memorial Hospital of Rhode Island
University of California, San Diego; National Heart, Lung, and Blood Institute... and other collaborators

Unknown

WHISH-2-Prevent Heart Failure

Heart Failure | Physical Activity | Elderly | Heart Failure With Reduced Ejection Fraction | Heart Failure With Normal Ejection Fraction | Women | Strength Training

United States
Northwestern University

Completed

Classification of Heart Failure With Preserved Ejection Fraction

Heart Failure With Preserved Ejection Fraction | Diastolic Heart Failure

United States
Novartis Pharmaceuticals

Completed

Safety and Tolerability Study of XXB750 in Heart Failure Participants With Reduced or Mildly Reduced Ejection Fraction (HFrEF/HFmrEF)

Heart Failure With Reduced Ejection Fraction (HFrEF) | or Heart Failure With Mildly Reduced Ejection Fraction (HFmrEF)

Netherlands, United States
US Department of Veterans Affairs

Completed

Extension of the MIME Robotic System for Stroke Rehabilitation

Stroke | Impaired Upper Extremity Function

United States
Beth Israel Deaconess Medical Center

Recruiting

Purinergic Signaling and the Postmenopausal Heart

Heart Failure With Preserved Ejection Fraction | Diastolic Heart Failure

United States
University of Alabama at Birmingham
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Left Ventricular Torsional Hysteresis: A Global Parameter for Diastolic Function

Heart Failure | Diastolic Heart Failure | Heart Failure With Normal Ejection Fraction

United States
Weill Medical College of Cornell University
National Institute on Aging (NIA)

Completed

Pilot Deprescribing N-of-1 Trials for Beta-blockers in HFpEF

Heart Failure | Heart Disease | Heart Failure, Diastolic | Heart Failure With Preserved Ejection Fraction | Cardiac Failure

United States
University of Michigan

Completed

Role of Exercise in Diastolic Heart Failure

Heart Failure With Preserved Ejection Fraction | Diastolic Heart Failure

United States
University of Virginia

Recruiting

Colchicine in Acutely Decompensated HFREF

Heart Failure | Decompensated Heart Failure | Heart Failure With Reduced Ejection Fraction

United States
Weill Medical College of Cornell University
The New York Community Trust

Completed

Impact of Beta-blockers on Physical Function in HFpEF

Heart Failure | Heart Disease | Heart Failure, Diastolic | Heart Failure With Preserved Ejection Fraction | Cardiac Failure

United States
Stanford University

Terminated

Quality of Life in Adults Impaired Functioning - A Randomized Controlled Trial of Bidet vs Usual Toileting

Toileting in Adults With Impaired Functional Status | Caregiver Burden for Those Who Care for Adults With Impaired Functional Status | UTI in Adults With Impaired Functional Status

United States
Mayo Clinic

Completed

Resistance Training in HFpEF

Heart Failure Preserved Ejection Fraction

United States
Sardocor Corp.

Recruiting

Modulation of SERCA2a of Intra-myocytic Calcium Trafficking in Heart Failure With Preserved Ejection Fraction (MUSIC-HFpEF)

Heart Failure, Diastolic | Heart Failure With Preserved Ejection Fraction

United States

Clinical Trials on Heart Failure and Impaired Kidney Function in United States

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