Clinical Trials on Heart Valve Disease

Total 381112 results

Technische Universität Dresden
Zentrum für Klinische Studien Leipzig; University Medical Center Mainz; KKS Dresden

Recruiting

Treatment of Concomitant Mitral Regurgitation by Mitral Valve Clipping in Patients With Successful Transcatheter Aortic Valve Implantation. (MITAVI)

Aortic Stenosis | Mitral Regurgitation

Germany
Admedus Regen Pty Ltd.

Completed

CardioCel Tri-leaflet Repair Study (CTRS)

Aortic Stenosis | Aortic Insufficiency

Belgium
Sorin Group USA, Inc.

Completed

Freedom SOLO Stentless Heart Valve Study (SOLO)

Aortic Stenosis | Aortic Insufficiency

United States, Canada
Gruppo di Ricerca GISSI

Completed

Investigation of Patients With BAV Requiring Valve and/or Aortic Repair (GISSI Outliers VAR) (VAR)

Aortic Regurgitation | Bicuspid Aortic Valve | Aortic Dilatation

Italy
Papworth Hospital NHS Foundation Trust

Recruiting

Quality of Life After Cardiac Surgery (QUACS)

Aortic Valve Stenosis | Coronary Artery Bypass Graft | Mitral Valve Disease | Tricuspid Valve Disease | Aorta Disease

United Kingdom
Deutsches Herzzentrum Muenchen
Department of Cardiovascular Surgery, German Heart Center Munich

Recruiting

TriRec - Trileaflet Reconstruction of the Aortic Valve With Autologous Pericardium (TriRec)

Alternative Surgical Treatment for Aortic Valve Disease

Germany
Centre Chirurgical Marie Lannelongue
Easy-CRF

Recruiting

European Multicentre Registry of Percutaneous Paravalvular Leak Closure (EuroPVL)

Quality of Life | Cardiac Valve Disease | Outcomes | Paravalvular Aortic Regurgitation | Paravalvular Mitral Regurgitation | Paravalvular Leak

Belgium, France, Poland, United Kingdom, Czechia, Greece, Italy, Latvia, Lithuania, Mexico, Spain, Turkey
Sahajanand Medical Technologies Limited
Qmed Consulting A/S

Recruiting

Hydra Single-centre Experience - Copenhagen, Denmark

Aortic Valve Stenosis

Denmark
Fundación EPIC

Recruiting

Evaluation of the Viability and Safety of Early Discharge Protocol After TAVI Implantation (FAST TRACK)

Aortic Valve Stenosis | Aortic Valve Disease | Heart Valve Diseases

Spain
Ole De Backer

Recruiting

Re-hospitalisation After Transcatheter Aortic Valve Implantation (HOSPITAVI)

Aortic Valve Stenosis | Aortic Valve Disease

Denmark
Guilherme Attizzani, MD

Recruiting

MRI in Transcatheter Aortic Valve Replacement Patients (MRI in TAVR)

Aortic Valve Stenosis

United States
Leipzig Heart Science gGmbH
Heart Center Leipzig - University Hospital

Recruiting

RanDOmized stUdy Comparing Both Latest Generation Self-Expanding Valves and a Minimalist approaCH vs. Standard Of Care In transCathEter Aortic Valve Implantation (DOUBLE-CHOICE)

Aortic Valve Stenosis

Germany
Universitätsklinikum Hamburg-Eppendorf

Recruiting

Hamburg AoRtic Valve cOhoRt (HARbOR)

Aortic Valve Stenosis

Germany
Seung-Jung Park
CardioVascular Research Foundation, Korea

Recruiting

Evaluation of Effectiveness and Safety of Aortic Valve Replacement in Routine Clinical Practice (IRIS AVR)

Aortic Valve Stenosis | Aortic Valve Disease

Korea, Republic of
Ho-Jin Kim
CardioVascular Research Foundation, Korea

Recruiting

ASAN Medical Center Aortic Valve Replacement Registry (ASAN-AVR)

Aortic Valve Stenosis

Korea, Republic of
Corcym S.r.l

Active, not recruiting

PERCEVAL S Valve Clinical Study for Chinese Registration (PERFECT)

Aortic Valve Stenosis | Aortic Valve Disease

China
University Hospital, Montpellier
Edwards Lifesciences

Completed

TAVI Without Balloon Predilatation (of the Aortic Valve ) SAPIEN 3 (DIRECTAVI)

Aortic Valve Stenosis

France
University Hospital, Basel, Switzerland

Completed

Sizing of the PERCEVAL® Sutureless Aortic Valve Prosthesis Using the CT: a Feasibility Study

Aortic Valve Stenosis

Switzerland
Aesculap AG
B.Braun Surgical SA

Completed

PremiCron Suture for Cardiac Valve Repair (PremiValve)

Aortic Valve Stenosis

Spain, Germany
Medtronic Cardiovascular

Completed

The Medtronic TAVR 2.0 US Clinical Study

Aortic Valve Stenosis

United States
University Hospital, Bordeaux

Completed

Safety Profile Evaluation of TICagrelor Alone Compared to a Combination of Lysine Acetylsalicylate-Clopidogrel in the Context of Transcatheter Aortic Valve Implantation (TAVI) (TICTAVI)

Aortic Valve Stenosis

France
Leipzig Heart Institute GmbH

Completed

Randomized Comparison of Catheter-based Strategies for Interventional Access Site Closure During Transfemoral Transcatheter Aortic Valve Implantation (CHOICE-CLOSURE)

Aortic Valve Stenosis

Germany
Karolinska University Hospital
Karolinska Institutet

Completed

Bleeding in Partial Upper Hemisternotomy Versus Full Sternotomy Aortic Valve Replacement

Aortic Valve Stenosis | Heart Valve Diseases

Sweden
University Hospital, Montpellier

Active, not recruiting

Follow-up After TAVR Without Systematic Intensive Care Unit Admission (TAVICU)

Aortic Valve Stenosis

France
University of Athens

Completed

A Trial to Assess the Safety and Efficacy of Prophylactic TicagrelOr With Acetylsalicylic Acid Versus CLopidogrel With Acetylsalicylic Acid in the Development of Cerebrovascular EMbolic Events During TAVI (PTOLEMAIOS)

Aortic Valve Stenosis

Greece
Karolinska University Hospital

Unknown

Vascular Closure Device in Transcatheter Aortic Valve Replacement

Aortic Valve Stenosis

Sweden
Edwards Lifesciences

Completed

PREVAIL-TA: Placement of Aortic Balloon Expandable Transcatheter Valves Trial (Europe)

Aortic Valve Stenosis

United Kingdom, Germany, France, Austria
CVPath Institute Inc.
Boston Scientific Corporation

Completed

Sentinel Low Risk Registry

Aortic Valve Stenosis

United States
Ceric Sàrl
Symetis SA

Completed

Safety and Efficacy Comparison Of Two TAVI Systems in a Prospective Randomized Evaluation II (SCOPE II)

Aortic Valve Stenosis

Germany, France, Spain, United Kingdom, Denmark, Italy
Medtronic Cardiovascular

Completed

CoreValve™ Evolut R™ FORWARD Study (FORWARD)

Aortic Valve Stenosis

Netherlands, Saudi Arabia, Italy, Germany, Sweden, Spain, Australia, France, United Kingdom, Belgium, Greece, Hungary, Israel, Canada, Colombia, South Africa, Czechia, Norway, Panama, Poland, Portugal
Medical University of Gdansk

Completed

Analgesia in Patients Undergoing Transfemoral Transcatheter Aortic Valve Implantation (TF-TAVI) (TF-TAVI)

Aortic Valve Stenosis

Poland
Medtronic Cardiovascular
Medtronic Australasia

Completed

CoreValve® System Australia/New Zealand Clinical Study

Aortic Valve Stenosis

New Zealand, Australia
Region Örebro County

Terminated

Characterization and Role of Mutations in Sodium-phosphate Cotransporters in Patients With Calcific Aortic Valve Disease

Aortic Valve Stenosis

Sweden
Boston Scientific Corporation

Withdrawn

REPRISE EDGE 29 mm EU Study

Aortic Valve Stenosis
Medtronic Bakken Research Center

Completed

Clinical Evaluation of Percutaneous Implantation of the Medtronic CoreValve Aortic Valve Prosthesis (18Fr-Study)

Aortic Valve Stenosis

Netherlands, Canada, United Kingdom, Germany
Abbott Medical Devices

Completed

Long Term Follow-up of the 23mm Portico™ Aortic Valve Implant and the St. Jude Medical Transfemoral Delivery System

Aortic Valve Stenosis

Canada
Medtronic Bakken Research Center

Completed

Transapical Implantation of the Medtronic Engager Transcatheter Aortic Valve Implantation System - The Engager European Pivotal Trial

Aortic Valve Stenosis

Germany, Israel, Belgium, Switzerland
Medtronic Bakken Research Center

Completed

Engager Direct Aortic Clinical Study

Aortic Valve Stenosis

United Kingdom, Germany, Czechia
BC Centre for Improved Cardiovascular Health
University of British Columbia

Completed

The Multidisciplinary, Multimodality, But Minimalist Approach to Transfemoral Transcatheter Aortic Valve Replacement (3MTAVR)

Aortic Valve Stenosis

Canada
Institut für Pharmakologie und Präventive Medizin

Completed

Balloon Expandable Transcatheter Aortic Valve Implantation Without Predilation of the Aortic Valve (EASE-IT)

Aortic Valve Stenosis

Germany
Medtronic Bakken Research Center

Completed

Engager Align Post-market Clinical Study

Aortic Valve Stenosis

Netherlands
Institut für Pharmakologie und Präventive Medizin

Completed

CGA-TAVI Registry to Evaluate the Predictive Value of a CGA in Predicting TAVI Outcomes (CGA-TAVI)

Aortic Valve Stenosis

Canada, Italy, Netherlands
C. R. Bard

Completed

Evaluation of the BARD® True™ Flow Valvuloplasty Perfusion Catheter for Aortic Valve Dilatation (True™Flow)

Aortic Valve Stenosis

Germany
University of Michigan

Terminated

Non-Contrast Magnetic Resonance Angiography Assessment of Patients Referred for Transcatheter Aortic Valve Implantation

Aortic Valve Stenosis

United States
Direct Flow Medical, Inc.

Unknown

TranScatheter Aortic Valve RepLacement System US Feasibility Trial (SALUS)

Aortic Valve Stenosis

United States
InterValve, Inc.

Completed

Impact of Postdilatation With the InterValve V8 Aortic Valvuloplasty Balloon Following TAVI Procedure (PostCorE)

Aortic Valve Stenosis
Keystone Heart

Completed

DEFLECT III: A Prospective, Randomized Evaluation of the TriGuard™ HDH Embolic Deflection Device During TAVI (TAVI)

Aortic Valve Stenosis

Netherlands, Israel, United Kingdom, Germany, France, Italy
Keystone Heart

Completed

DEFLECT II: A Study to Evaluate the Safety and Performance of the TriGuard™HDH in Patients Undergoing TAVR

Aortic Valve Stenosis

Netherlands
Universiteit Antwerpen

Recruiting

Belgian Mitraclip Registry

Mitral Valve Insufficiency

Belgium
Boston Scientific Corporation

Completed

Annular Reshaping of the Mitral Valve for Patients With Mitral Regurgitation Using the Millipede IRIS System

Mitral Valve Insufficiency

Brazil, Paraguay

Clinical Trials on Heart Valve Disease

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Malawi

Conditions

Rare Diseases

Drug Interventions

Dietary Supplements

Sponsor/Collaborators

Locations