Clinical Trials on Hepatic Insufficiency

Total 12705 results

Third Affiliated Hospital, Sun Yat-Sen University

Unknown

Prognosis Scoring System for Acute-on-Chronic Liver Failure

Liver Failure
Bristol-Myers Squibb

Completed

An Investigational Study of Experimental Medication BMS-986231 Given in Participants With Different Levels of Liver Function

Congestive Heart Failure | Liver Dysfunction | Heart Decompensation | Cardiac Failure | Liver Insufficiency | Myocardial Failure | Hepatic Failure

Hungary, Poland
Ningbo Medical Center Lihuili Hospital

Recruiting

Fecal Microbiota Transplantation for Liver Failure

Liver Failure

China
Sun Yat-sen University

Completed

The Efficacy and Safety of Thymosin-α1 in Patients With HBV-related ACLF

Liver Failure

China
University Hospital Inselspital, Berne

Terminated

Terlipressin Administration in Patients Undergoing Major Liver Resection

Liver Failure | Liver Resection

Switzerland
Eli Lilly and Company

Completed

A Pharmacokinetic Study of Baricitinib in Participants With Liver Disease

Liver Diseases | Hepatic Insufficiency

United States
Puma Biotechnology, Inc.

Completed

Study Evaluating The PK And Safety Of Neratinib In Healthy Subjects And Subjects With Chronic Liver Disease

Hepatic Insufficiency

Russian Federation
William Lee
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Completed

A Multi-Center Trial to Study Acute Liver Failure in Adults (ALFSG)

Acute Liver Failure | Fulminant Hepatic Failure | Acute Liver Injury

United States, Canada
Groupe Hospitalier Pitie-Salpetriere

Completed

Monitoring the HePAtological TOXicity of Drugs (HePATOX) (HePATOX)

Liver Diseases | Liver Failure | Liver Dysfunction | Hepatotoxicity

France
Sun Yat-sen University

Unknown

Allogenic Bone Marrow Stem Cell Transplantation in Liver Failure

Liver Failure

China
Jinnah Postgraduate Medical Centre

Not yet recruiting

Efficacy of L-Ornithine L-Aspartate and Polyethylene Glycol in Cirrhotic Patients With Overt Hepatic Encephalopathy

Hepatic Encephalopathy Stage 2 | Hepatic Encephalopathy Stage 3 | Hepatic Encephalopathy Stage 4

Pakistan
University Hospital Birmingham NHS Foundation Trust

Completed

Myocardial Perfusion Imaging in Liver Transplantation Candidates (ExSPECT)

Liver Failure | Myocardial Perfusion Imaging
Nhat Nhat Pharmaceutical Company

Unknown

TONKA Versus Legalon for Lowering Hepatic Enzymes in Liver Function Disorder Patients.

Liver Function Failure

Vietnam
Beijing 302 Hospital

Unknown

Safety and Efficacy of Human Mesenchymal Stem Cells for Treatment of Liver Failure

Liver Failure | Mesenchymal Stem Cells

China
Third Affiliated Hospital, Sun Yat-Sen University

Unknown

Umbilical Cord Mesenchymal Stem Cells Transplantation Combined With Plasma Exchange for Patients With Liver Failure

Liver Failure

China
Sun Yat-sen University

Unknown

Allogeneic Bone Marrow Mesenchymal Stem Cells Transplantation in Patients With Liver Failure Caused by Hepatitis B Virus (HBV)

Liver Failure
Sherief Abd-Elsalam
Tanta University

Unknown

Nitazoxanide Plus Lactulose Versus Lactulose Alone Treatment of Hepatic Encephalopathy

Encephalopathy, Hepatic

Egypt
University of Cincinnati

Completed

Telemedicine Based Remote Home Monitoring After Liver Transplantation (TelehealthOLT)

Liver Failure | Liver Transplant; Complications
Institute of Liver and Biliary Sciences, India

Withdrawn

High Volume Plasmapheresis for Refractory Hepatic Encephalopathy in Liver Intensive Care Unit.

Refractory Hepatic Encephalopathy

India
Tel-Aviv Sourasky Medical Center

Unknown

A Nutritional Approach to Minimal Hepatic Encephalopathy

Minimal Hepatic Encephalopathy

Israel
University of Edinburgh
NHS Lothian

Not yet recruiting

Biomarkers in Liver Failure

Acute on Chronic Hepatic Failure | Acute Liver Failure | Acute Liver Injury
Medical University of South Carolina
Emory University

Completed

Study to Evaluate if the Drug Vasopressin Protects the Kidneys for Patients Undergoing Liver Transplant

Liver Failure

United States
Shanghai Changzheng Hospital

Enrolling by invitation

Utility of the Clamping Bean Test (CBT) for Covert Hepatic Encephalopathy Screening

Hepatic Encephalopathy | Covert Hepatic Encephalopathy

China
Bausch Health Americas, Inc.

Completed

Rifaximin Soluble Solid Dispersion (SSD) Tablets Plus Lactulose for the Treatment of Overt Hepatic Encephalopathy (OHE) (OHE)

Overt Hepatic Encephalopathy

United States
Shanghai Changzheng Hospital

Completed

Low-dose Rifaximin in the Treatment of Covert Hepatic Encephalopathy

Covert Hepatic Encephalopathy

China
Fondazione Policlinico Universitario Agostino Gemelli...

Completed

Transcranial Doppler Ultrasound and Minimal Hepatic Encephalopathy

Minimal Hepatic Encephalopathy

Italy
Imperial College London

Completed

Adult Stem Cell Therapy in Liver Insufficiency

Liver Cirrhosis

United Kingdom
The University of Texas Medical Branch, Galveston

Terminated

Evaluation of Mechanisms Responsible for Coma in Patients Affected by Fulminant, Acute and Chronic Hepatic Failure

Acute and Chronic Hepatic Failure With Developing Coma

United States
Ain Shams University

Completed

Reversibility of Minimal Hepatic Encephalopathy Following Liver Transplantation

Minimal Hepatic Encephalopathy
Mansoura University

Completed

Antioxidants and Zinc Improving Minimal Hepatic Encephalopathy In Truck Drivers; a Pilot Study

Minimal Hepatic Encephalopathy

Egypt
Nanfang Hospital, Southern Medical University

Recruiting

Evaluating the Association Between Sphingolipid Metabolites and Post-hepatectomy Liver Failure

Post-hepatectomy Liver Failure

China
Novartis Pharmaceuticals

Completed

Pharmacokinetics of Everolimus in Subjects With Hepatic Insufficiency

Hepatic Insufficiency

Germany, Russian Federation, Singapore
Karolinska University Hospital

Completed

Early Postoperative Extracorporal Liver Support Therapy (ELS) as a Tool to Manage Post Hepatectomy Liver Failure (PLF)

Post Hepatectomy Liver Failure

Sweden
Shanghai Zhongshan Hospital

Unknown

The Effect of Terlipressin on Recovery of Liver Function After Hepatectomy

Liver Failure | Acute Kidney Injury | Ascites Hepatic | Terlipressin Adverse Reaction

China
Eastern Hepatobiliary Surgery Hospital

Not yet recruiting

A Prospective Cohort Study on the Prediction of PHLF by Comparing the Prediction Model Based on VEGFA and PEDF With Indocyanine Green Clearance Test

Liver Failure After Operative Procedure
Gilead Sciences

Recruiting

Study of Sacituzumab Govitecan in Participants With Advanced or Metastatic Solid Tumor and Moderate Liver Impairment

Liver Failure | Advanced or Metastatic Solid Tumor

France, United States
Ira Fox

Withdrawn

Hepatocyte Transplantation for Acute Decompensated Liver Failure

Liver Failure Acute

United States
Hunter Holmes Mcguire Veteran Affairs Medical Center
Instituto Grifols, S.A.; McGuire Research Institute

Completed

HEAL STUDY (Hepatic Encephalopathy and Albumin Study) (HEAL)

Hepatic Encephalopathy | Cirrhosis | Minimal Hepatic Encephalopathy | Covert Hepatic Encephalopathy

United States
Instituto Nacional de Ciencias Medicas y Nutricion...

Completed

Hyperproteic Diet Plus Lactobacillus Reuteri and Nitazoxanide in Minimal Hepatic Encephalopathy

Hepatic Cirrhosis | Minimal Hepatic Encephalopathy

Mexico
Institute of Liver and Biliary Sciences, India

Not yet recruiting

Efficacy of L-ornithine L-aspartate and Therapeutic Plasma Exchange Versus Plasma Exchange Alone in Lowering Ammonia and Improving Outcomes in Pediatric Acute Liver Failure.

Liver Failure, Acute

India
Quell Therapeutics Limited

Recruiting

Safety and Clinical Activity of QEL-001 in A2-mismatch Liver Transplant Patients (LIBERATE)

Liver Diseases | Liver Failure | Rejection; Transplant, Liver

Belgium, United Kingdom, Spain
Boehringer Ingelheim

Completed

Study to Evaluate the Effects of Underlying Renal or Hepatic Dysfunction on the Pharmacokinetics of Nevirapine

Hepatic Insufficiency | Renal Insufficiency
Consorci Sanitari de l'Alt Penedès i Garraf

Withdrawn

GELSECTAN® and Covert Hepatic Encephalopathy (GELSECTAN)

Covert Hepatic Encephalopathy

Spain
Pere Gines
Clinica Universidad de Navarra, Universidad de Navarra

Terminated

Allogenic Bone Marrow Mesenchymal Stem Cell Therapy in Acute-on-chronic Liver Failure (Liveradvance)

Acute on Chronic Hepatic Failure

Spain
Virginia Commonwealth University
National Center for Complementary and Integrative Health (NCCIH)

Completed

Probiotic Lactobacillus GG (LGG) in Patients With Minimal Hepatic Encephalopathy

Minimal Hepatic Encephalopathy

United States
Assiut University

Recruiting

Throid Dysfunction in Liver Failure and Its Eddects Upon Outcome

Hepatic Encephalopathy | Hypothyroidism | Hepatic Impairment | Hepatic Failure

Egypt
Mallinckrodt

Completed

MNK6106 for Liver Disease (Hepatic Cirrhosis) That in the Past Has Affected the Brain (Hepatic Encephalopathy)

Hepatic Cirrhosis | Hepatic Encephalopathy (HE)

United States, Puerto Rico
Javelin Pharmaceuticals

Completed

Open-Label, Single-Dose Study to Evaluate the Safety and PK of DIC075V in Subjects With Renal Insufficiency and Hepatic Impairment Compared to Healthy Subjects and Evaluate the Safety and Pharmacokinetics of HPβCD When Administered in DIC075V Compared to Sporanox® in Healthy Subjects

Hepatic Insufficiency | Healthy | Renal Insufficiency, Chronic

United States, United Kingdom
Institutul Clinic Fundeni

Completed

Perioperative Lactate Kinetics in Patient Undergoing Major Liver Surgery

Liver Failure, Acute

Romania
Shanghai East Hospital
Chinese Academy of Sciences

Unknown

Safety and Efficacy of hiHep Bioartificial Liver Support System to Treat Acute Liver Failure

Liver Failure, Acute

Clinical Trials on Hepatic Insufficiency

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