Clinical Trials on Hepatic Encephalopathy

Total 3499 results

Assiut University

Unknown

Implication of Fluid Strategies Upon Hepatic Outcome in Hepatobiliary Surgery

Hepatic Complication
Novartis Pharmaceuticals

Completed

Pharmacokinetic Study of Icenticaftor in Participants With Hepatic Impairment

Hepatic Failure

United States
Daiichi Sankyo, Inc.

Completed

A Study of Quizartinib Pharmacokinetics in Participants With Moderate Hepatic Impairment

Hepatic Impairment | Moderate Impaired Hepatic Function

United States
Mitsubishi Tanabe Pharma Corporation

Completed

PK Study in Subjects With Severe Hepatic Impairment (MCI-186-E05 HP)

Healthy | Severe Hepatic Impairment

Czechia, Hungary, Slovakia
Drexel University

Completed

Pharmacokinetics of Ampicillin in Neonates With Moderate to Severe Hypoxic-Ischemic Encephalopathy

Hypothermia

United States
University of Mississippi Medical Center

Terminated

Eclampsia and Posterior Reversible Encephalopathy Syndrome (PRES): (PRESIDEX)

Eclampsia

United States
Neurocrine Biosciences

Enrolling by invitation

Extension Study to Evaluate NBI-827104 in Pediatric Participants With Epileptic Encephalopathy With Continuous Spike-and-Wave During Sleep (Steamboat 2)

Epileptic Encephalopathy | Continuous Spike and Wave During Sleep

United States, Denmark, Spain, Switzerland, United Kingdom
Medical University of Vienna
Bodychillz Ltd

Withdrawn

Prehospital Non-invasive Cooling of Comatose Patients After Cardiac Arrest

Cardiac Arrest | Postresuscitation Encephalopathy

Austria
Liaocheng People's Hospital

Unknown

Treatment of Human Cord Blood Mononuclear Cell for Delayed Encephalopathy After Carbon Monoxide Poisoning

Delayed Encephalopathy After Carbon Monoxide Poisoning

China
KBP Biosciences
Covance

Completed

Pharmacokinetics of KBP-5074 in Patients With Moderate Hepatic Impairment

Healthy | Moderate Hepatic Impairment

United States
Centre Hospitalier Universitaire de Nice

Completed

Pyrophosphate Homeostasis and Hepatic Expression of ABCC6.Pyro-TH (Pyro-TH)

Hepatic Failure

France
Rennes University Hospital

Completed

Comparison of the Variability of Hepatic Load Quantification in Iron and Fat Estimated by MRI at 1.5 and 3 Tesla (HEMOCOMPARE)

Iron Hepatic Overload | Fat Hepatic Overload

France
Biotie Therapies Inc.
Acorda Therapeutics

Terminated

Study to Investigate the Influence of Hepatic Insufficiency on the Pharmacokinetics of Tozadenant

Hepatic Impairment

United States
Tibotec BVBA

Completed

A Study of TMC207 in Patients With Moderately Impaired Hepatic Function

Moderate Hepatic Impairment
Pfizer
Medivation, Inc.

Completed

Study To Evaluate The Pharmacokinetics, Safety, And Tolerability Of Dimebon [Pf-01913539] In Subjects With Hepatic Impairment And Normal Hepatic Function

Hepatic Failure

United States
Jazz Pharmaceuticals

Completed

Assessment of the Single Dose Pharmacokinetics and Tolerability of Sativex in Patients With Impaired Hepatic Function and Healthy Patients

Hepatic Impairment

United States
Seagen Inc.

Completed

A Safety Study of Tucatinib in Healthy and Hepatically-Impaired Subjects

Hepatic Impairment

United States
Mansoura University

Completed

Clamp-crush Technique Versus Harmonic Scalpel in Living Donor Hepatectomy (KK_HS)

Hepatic Transplantation

Egypt
Nuh Rahbari

Completed

Stapler Hepatectomy for Elective Liver Resection (CRUNSH)

Hepatic Resection

Germany
AdventHealth

Completed

Endoscopic Ultrasound Guided Liver Biopsy

Hepatic Cancer | Hepatic Carcinoma | Hepatic Neoplasm

United States
Thayyil, Sudhin
Wayne State University

Active, not recruiting

Optimising the Duration of Cooling in Mild Encephalopathy (COMET)

Neonatal Encephalopathy | Magnetic Resonance Spectroscopy | Hypothermia Neonatal

United Kingdom, United States, Italy
Hospital Ruber Internacional
Zogenix, Inc.

Recruiting

Fenfluramine for the Treatment of Different Types of Developmental and Epileptic Encephalopathies: a Pilot Trial Exploring Epileptic and Non-epileptic Outcomes (FENDEEP)

Refractory Epilepsy | STXBP1 Encephalopathy With Epilepsy | SYNGAP1 Encephalopathy | Inv Dup(15) Encephalopathy | Multifocal or Bilateral Malformations of Cortical Development | Continuous Spike and Waves During Slow Sleep

Spain
The Hospital for Sick Children

Not yet recruiting

Early Virtual Intervention for Infants With CP Following HIE Diagnosis (RECOVER)

Cerebral Palsy | Brain Injuries | Hypoxic-Ischemic Encephalopathy | Perinatal Hypoxia

Canada
Semmelweis University

Completed

Hydrocortisone Treatment In Systemic Low Blood Pressure During Hypothermia in Asphyxiated Newborns (CORTISoL)

Asphyxia | Hypoxic-Ischemic Encephalopathy

Hungary
Albany Medical College
Medtronic

Terminated

The Ability of NIRS to Predict Brain Injury in Hypoxic Ischemic Encephalopathy

HIE - Perinatal Hypoxic - Ischemic Encephalopathy

United States
Semmelweis University

Completed

Hypoxic-Ischemic Encephalopathy Therapy Optimization in Neonates for Better Neuroprotection With Inhalative CO2 (HENRIC)

Perinatal Asphyxia | Hypocapnia | Hypoxic-Ischaemic Encephalopathy

Hungary
Children's Hospital Medical Center, Cincinnati
The Gerber Foundation

Completed

Protein Supplementation in Infants With Brain Injury

Perinatal Stroke | White Matter Injury | Hypoxic-ischemic Encephalopathy

United States
Sunshine Lake Pharma Co., Ltd.

Completed

To Evaluate the Pharmacokinetics and Safety of Yimitasvir Phosphate Capsules in Subjects With Moderate and Severe Liver Function Impairment and in Healthy Subjects

Hepatic Impairment

China
Central Hospital, Nancy, France

Completed

Hepatic Artery From Origin to Segmental Branching: a 500 Case CT Study

Hepatic Artery

France
Janssen Research & Development, LLC

Withdrawn

A Study to Investigate the Pharmacokinetics, Safety, and Tolerability of Odalasvir and AL-335 Alone and in Combination With Simeprevir in Participants With Moderately Impaired Hepatic Function

Hepatic Impairment
University of Saskatchewan

Active, not recruiting

Cannabidiol in Children With Refractory Epileptic Encephalopathy (CARE-E)

Epileptic Encephalopathy

Canada
University of Florida
Thrasher Research Fund

Recruiting

Melatonin as a Neuroprotective Therapy in Neonates With HIE Undergoing Hypothermia

Hypoxic Ischemic Encephalopathy

United States
Dunjin Chen

Not yet recruiting

Long-term Consequences of Neuroimaging and Perceived Cognitive Dysfunction in oPRES

Cognitive Dysfunction | Neuroimaging | Posterior Reversible Encephalopathy Syndrome

China
Assistance Publique - Hôpitaux de Paris

Completed

Build a Decision Aid Tool to Help Emergency Intensive Care Specialists in the Context of Hypoxic Ischemic Encephalopathy (NewbornDS)

Encephalopathy

France
National Institute of Mental Health (NIMH)

Completed

PET Imaging in Chronic Traumatic Encephalopathy

Brain Disease | Brain Mapping

United States
University of Florida
American Heart Association

Completed

Clinical Utility of Serum Biomarkers for the Management of Neonatal Hypoxic Ischemic Encephalopathy (Control Levels)

Hypoxic Ischemic Encephalopathy

United States
Vanderbilt University
National Institutes of Health (NIH)

Withdrawn

MRI Thermal Imaging of Infants Undergoing Cooling for Hypoxic Ischemic Encephalopathy(HIE)

Hypoxic Ischemic Encephalopathy

United States
Hebei Medical University

Unknown

Umbilical Cord Derived Mesenchymal Stem Cells Therapy in Hypoxic Ischemic Encephalopathy

Hypoxic Ischemic Encephalopathy

China
BeiGene

Completed

Safety and Pharmacokinetics of Zanubrutinib (BGB-3111) in Healthy Subjects and Those With Impaired Liver Function

Hepatic Insufficiency & Healthy Subjects

United States
National Taiwan University Hospital

Unknown

Oxidative Stress and Microcirculation in Patient With Hepatic Failure Undergoing Liver Support Treatment

Liver Failure | Critical Care

Taiwan
Children's Hospital of Philadelphia
Bracco Diagnostics, Inc

Recruiting

CEUS Evaluation of Hypoxic Ischemic Injury

Hypoxic-Ischemic Encephalopathy | Brain Ischemia Hypoxia

United States
Asan Medical Center

Unknown

Targeted Temperature Management After In-Hospital Cardiac Arrest (TTM36-IHCA)

Hypoxic Ischemic Encephalopathy

Korea, Republic of
Charite University, Berlin, Germany

Completed

The Neurological Pupil Index (NPi) on Intensive Care Unit (ICU) Trial (NPI-ON-ICU)

Hypoxic Encephalopathy

Germany
Pfizer

Completed

A Study To Describe The Effect Of Impaired Hepatic Function Of The Pharmacokinetics Of Palbociclib

Healthy, Hepatic Insufficiency

United States
Neurocrine Biosciences

Recruiting

Study to Evaluate NBI-921352 as Adjunctive Therapy in Subjects With SCN8A Developmental and Epileptic Encephalopathy Syndrome (SCN8A-DEE)

SCN8A Developmental and Epileptic Encephalopathy Syndrome

United States
Neurocrine Biosciences

Enrolling by invitation

Extension Study to Evaluate How Safe and Tolerable NBI-921352 is as an Adjunctive Therapy for Participants With SCN8A-DEE

SCN8A Developmental and Epileptic Encephalopathy Syndrome

United States
ReAlta Life Sciences, Inc.
Premier Research Group plc

Recruiting

A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Preliminary Efficacy of RLS-0071 in Newborns With Moderate or Severe Hypoxic-Ischemic Encephalopathy Undergoing Therapeutic Hypothermia (STAR)

Hypoxic-Ischemic Encephalopathy

United States
Nemours Children's Clinic
Eunice Kennedy Shriver National Institute of Child Health and Human Development... and other collaborators

Recruiting

Comparative Outcomes Related to Delivery-room Cord Milking In Low-resourced Kountries Developmental Follow Up (CORDMILK-FU)

Hypoxic-Ischemic Encephalopathy | Birth Asphyxia

India
Daping Hospital and the Research Institute of Surgery...
Children's Hospital of Chongqing Medical University; Children's Hospital of... and other collaborators

Withdrawn

Whole-Body Hypothermia for Neonates With Hypoxic-Ischemic Encephalopathy(HIE)

Brain Injury | Hypoxic- Ischemic Encephalopathy | Whole-Body Hypothermia

China
Rigshospitalet, Denmark

Completed

Cerebral Microdialysis in Patients With Fulminant Hepatic Failure

Fulminant Hepatic Failure

Denmark

Clinical Trials on Hepatic Encephalopathy

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Belarus

Conditions

Rare Diseases

Drug Interventions

Dietary Supplements

Sponsor/Collaborators

Locations