Clinical Trials on Hepatic Function in Hungary

Total 103 results

Mitsubishi Tanabe Pharma Corporation

Completed

PK Study in Subjects With Severe Hepatic Impairment (MCI-186-E05 HP)

Healthy | Severe Hepatic Impairment

Czechia, Hungary, Slovakia
Novartis Pharmaceuticals

Completed

A Study to Investigate the Pharmacokinetics and Safety of Remibrutinib in Participants With Hepatic Impairment Compared With Matched Healthy Participants

Hepatic Impairment

Hungary
MedDay Pharmaceuticals SA
Eurofins Optimed

Terminated

HI Study to Assess and Compare the Pharmacokinetic Parameters of MD1003 in Hepatic Impaired Patients and Healthy Subjects

Healthy Volunteers | Hepatic Impairment of Moderate Child Pugh Category

France, Hungary
Chiesi Hungary Ltd.
Chiesi Slovenija, d.o.o.

Recruiting

Assessment of the Pharmacokinetic Profile of Tacrolimus Medications and Their Relation to Effectiveness and Safety in Liver Transplant Patients (LTA)

Liver Failure

Hungary, Slovenia
Idorsia Pharmaceuticals Ltd.

Recruiting

A Study to Investigate the Effect of Hepatic Impairment on the Pharmacokinetics of a Single Dose of Cenerimod

Healthy | Hepatic Impairment

Portugal, Hungary
Denovo Biopharma LLC

Completed

A Study of LY2140023 in Hepatically-Impaired Participants

Hepatic Insufficiency

Germany, Hungary
GlaxoSmithKline

Completed

A Study Of GW406381 In Volunteers With Moderate Hepatic Impairment

Pain

Hungary
Novartis Pharmaceuticals

Completed

Pharmacokinetics of BAF312 in Patients With Hepatic Impairment

Hepatic Impairment

Hungary, Russian Federation
Takeda

Recruiting

A Study About Fazirsiran in People With and Without Liver Problems

Hepatic Impairment

Hungary, Slovakia
Novartis Pharmaceuticals

Completed

A Study to Evaluate the Pharmacokinetics of AFQ056 in Subjects With Hepatic Impairment Compared to Healthy Subjects

Hepatic Impairment

Germany, United States, Hungary
Szeged University

Recruiting

Late Respiratory Consequences of SARS-CoV-2 Pneumonia

Long COVID | Respiratory Function Tests

Hungary
Hoffmann-La Roche

Completed

A Study to Investigate the Effect of Impaired Hepatic Function on the Pharmacokinetics of Entrectinib in Volunteers With Different Levels of Hepatic Function

Hepatic Insufficiency

Hungary, Czechia, Slovakia
Bristol-Myers Squibb

Completed

An Investigational Study of Experimental Medication BMS-986231 Given in Participants With Different Levels of Liver Function

Congestive Heart Failure | Liver Dysfunction | Heart Decompensation | Cardiac Failure | Liver Insufficiency | Myocardial Failure | Hepatic Failure

Hungary, Poland
University of Debrecen

Completed

Diclofenac Premedication, as the Effect of Preemptive Analgesia After Post-thoracotomy Chest and Shoulder Pain

Pain | Inadequate or Impaired Respiratory Function

Hungary
Szeged University

Active, not recruiting

Respiratory Effects of Dopamine in the Perioperative Care (DOPHUMAN)

Surgery | Functional Disturbance | Dopamine | Bronchodilation | Heart

Hungary
Semmelweis University Heart and Vascular Center
Semmelweis University

Recruiting

The Role and Dynamics of Liver Dysfunction in Patients Undergoing Cardiac Surgery

Heart Failure | Cardiac Surgery | Hepatic Impairment

Hungary
University of Pecs

Suspended

Extracorporal Cytokin Removal in Septic Shock: a Prospective, Randomized, Multicenter Clinical Trial (DECRISS)

Septic Shock

Hungary
Zsolt Molnár, MD, PhD, DEAA

Completed

Adsorbtion of Cytokines Early in Septic Shock: the ACESS Study

Sepsis | Septic Shock

Hungary
Domonkos Trásy

Completed

Continuous Central Venous Oxygen Saturation Assisted Intraoperative Hemodynamic Management

Postoperative Complications | Major Abdominal Surgery | Perioperative Fluid Management | Perioperative Haemodynamic Monitoring | Perioperative Vasopressor Requirement | Postoperative Organ Function

Hungary
University of Pecs

Completed

Blessing or Curse? Combined Vitamin Therapy in Non Viral Septic Shock.

Septic Shock

Hungary
Takeda

Completed

A Study of Soticlestat in Adults With Liver Failure Compared to Those With Normal Liver Function

Healthy Volunteers | Hepatic Impairment

United States, Hungary
University of Debrecen

Enrolling by invitation

The Effect of Ginger on Functional Dyspepsia Symptoms and Body Fat Content Among Patients With Functional Dyspepsia

Functional Dyspepsia

Hungary
MedDay Pharmaceuticals SA
Eurofins Optimed

Terminated

RI Study to Assess and Compare the Pharmacokinetic Parameters of MD1003 in Renal Impaired Patients and Healthy Subjects

Healthy Volunteers | Impaired Renal Function

France, Hungary
Chiesi Farmaceutici S.p.A.

Withdrawn

Efficacy and Safety of CUSA-081 in the Restoration of Dysfunctional Central Venous Access Device (CVAD) Functionality (READY 2)

Restoration of Function to CVADs

United States, Bulgaria, Hungary
Eli Lilly and Company

Completed

A Single Dose Study of LY2605541 in Participants With Liver Impairment

Hepatic Insufficiency | Diabetes Mellitus, Type 2 | Healthy Volunteers

Germany, Hungary
Somogy Megyei Kaposi Mór Teaching Hospital

Completed

Effects of Intensity-matched Agility and Cycling Exercise Training on PD Patients' Clinical Symptoms, Posture, and Mobility

Parkinson Disease | Rehabilitation | Motor Function | Balance

Hungary
UMC Utrecht
ZonMw: The Netherlands Organisation for Health Research and Development

Terminated

Chest CT With Iterative Reconstruction as an Alternative to Conventional Chest X-ray Prior to Heart Surgery (CRICKET)

Stroke | Disorder; Heart, Functional, Postoperative, Cardiac Surgery | Cardiac Defects

Netherlands, Hungary
Sagimet Biosciences Inc.

Completed

A Phase I Pharmacokinetic Study of TVB-2640 (Denifanstat) in Subjects With Mild, Moderate, or Severe Hepatic Impairment Compared to Subjects With Normal Hepatic Function

Cirrhosis | Hepatic Impairment | Non-alcoholic Steatohepatitis

United States, Hungary
Novo Nordisk A/S

Completed

Pharmacokinetics, Safety and Tolerability of Oral Semaglutide in Subjects With Various Degrees of Impaired Renal Function

Healthy | Diabetes Mellitus, Type 2 | Diabetes

Hungary, Czechia
University of Pecs

Not yet recruiting

The Role of Irritable Bowel Syndrome in Lactose Intolerance (LION) (LION)

Irritable Bowel Syndrome | Lactose Intolerance | Lactose Malabsorption

Hungary
Szeged University

Recruiting

Open Label Single Arm Proof of Concept Trial to Evaluate the Efficacy and Safety of Cytori Celution System in Chronic Non-Healing Venous Leg Ulcers

Mesenchymal Stem Cells | Venous Leg Ulcer | Autologous Adipose Stromal Vascular Fraction | Adipose-Derived Mesenchymal Stem Cells

Hungary
Axcella Health, Inc

Terminated

Efficacy and Safety of AXA1665 in Cirrhotic Subjects With Prior Overt Hepatic Encephalopathy (EMMPOWER)

Hepatic Encephalopathy

Spain, United States, Canada, Italy, Hungary, Poland, United Kingdom
Szeged University

Recruiting

Open Label Single Arm Proof of Concept Trial to Evaluate the Efficacy and Safety of Cytori Celution System in Diabetic Leg Ulcers

Leg Ulcer | Diabetic Foot Ulcer | Mesenchymal Stem Cells | Autologous Adipose Stromal Vascular Fraction | Adipose-Derived Mesenchymal Stem Cells

Hungary
Novartis Pharmaceuticals

Completed

Efficacy, Safety and Tolerability of Everolimus in Combination With Reduced Exposure Cyclosporine or Tacrolimus in Paediatric Liver Transplant Recipients.

Renal Function | Liver Transplant

United States, Germany, Spain, Belgium, France, Hungary, Australia, Sweden, Italy, Canada, United Kingdom, Denmark
Ocera Therapeutics, Inc.

Completed

Phase 2B Efficacy/Safety of Ornithine Phenylacetate in Hospitalized Cirrhotic Patients With Hepatic Encephalopathy (STOP-HE) (STOP-HE)

Hepatic Encephalopathy | Acute Episode of Overt Hepatic Encephalopathy

Belgium, Germany, Italy, Spain, United States, France, Austria, Russian Federation, Czechia, Australia, Hungary, Israel, Netherlands, Bulgaria, Estonia, Denmark, New Zealand
Laboratoires Mayoly Spindler

Completed

Efficacy and Safety of Meteospasmyl® in Irritable Bowel Syndrome

Irritable Bowel Syndrome

Poland, Hungary
University of Pecs

Completed

Presepsin:Gelsolin Ratio in Sepsis-related Organ Dysfunction

Sepsis | Septic Shock | Acute Respiratory Distress Syndrome | Acute Kidney Injury Due to Sepsis

Hungary
Ionis Pharmaceuticals, Inc.

Completed

Safety, Tolerability, and Pharmacodynamics of IONIS-DGAT2Rx in Adult Patients With Type 2 Diabetes

Hepatic Steatosis

Canada, Hungary, Poland, United Kingdom
Novartis Pharmaceuticals

Completed

Study of Efficacy and Safety of DV890 in Patients With COVID-19 Pneumonia

COVID-19 Pneumonia, Impaired Respiratory Function

Germany, India, Spain, Russian Federation, Mexico, Netherlands, Peru, Brazil, Hungary, Argentina, Denmark, South Africa
Bausch Health Americas, Inc.

Active, not recruiting

Study to Assess Rifaximin Soluble Solid Dispersion (SSD) for the Delay of Encephalopathy Decompensation in Cirrhosis (RED-C-3132)

Hepatic Encephalopathy

United States, Australia, Belgium, Bulgaria, Canada, France, Germany, Hungary, India, Italy, Korea, Republic of, Mongolia, New Zealand, Poland, Puerto Rico, Spain, United Kingdom
Mardil Medical

Recruiting

VenTouch OUS Feasibility Study

Functional Mitral Regurgitation

Canada, Hungary, France, Germany, Netherlands, Panama, Poland
Ionis Pharmaceuticals, Inc.

Completed

A Study to Assess the Safety, Tolerability and Efficacy of IONIS-AGT-LRx in Participants With Chronic Heart Failure With Reduced Ejection Fraction (ASTRAAS-HF)

Chronic Heart Failure With Reduced Ejection Fraction

United States, Hungary, Poland
AbbVie
Ironwood Pharmaceuticals, Inc.

Recruiting

A Study to Assess Adverse Events and Change in Disease Activity in Pediatric Participants (Age 6 Months to <2 Years) With Functional Constipation Who Are Treated With Linaclotide

Functional Constipation

United States, Bulgaria, United Kingdom, Croatia, Germany, Hungary
AstraZeneca

Completed

Symptom Improvements in Gastroesophageal Reflux Disease (GERD) Patients

Gastroesophageal Reflux Disease (GERD)

Hungary, Romania, Norway, Belgium, France, Netherlands, Germany, Australia
Novartis Pharmaceuticals

Terminated

Dose Response Study of EMA401 in Patients With Post-herpetic Neuralgia (PHN) (EMPHENE)

Post-herpetic Neuralgia

Australia, Taiwan, Germany, France, Portugal, Czechia, United Kingdom, Hungary, Spain, Slovakia, Japan, Canada, Denmark, Norway, Austria, Belgium, Poland, Italy, Korea, Republic of
UCB Pharma

Completed

Study to Assess the Efficacy and Safety of Somatostatin in the Treatment of Acute Severe Upper Gastrointestinal Bleeding

Peptic Ulcer

France, Poland, Spain, Belgium, Greece, Hungary
Bayer
Merck Sharp & Dohme LLC

Recruiting

A Study to Learn How Safe Starting Vericiguat at a Dose of 5 Milligrams is in Participants With Chronic Heart Failure With Reduced Ejection Fraction

Chronic Heart Failure With Reduced Ejection Fraction

Spain, United States, Argentina, Hungary, Italy, Poland, Sweden
Jonel Trebicka

Completed

Predicting Acute-on-Chronic Liver Failure in Cirrhosis (PREDICT) Study (PREDICT)

Liver Cirrhosis With Acute Decompensation

Spain, Germany, Denmark, Austria, Belgium, United Kingdom, Netherlands, Switzerland, Hungary, Italy, France, Portugal, Slovakia, Turkey
Takeda

Completed

Efficacy of Pantoprazole in Patients Older Than 18 Years Who Have Symptoms of Acid Reflux (Gastroesophageal Reflux Disease) (BY1023/M3-339)

Gastroesophageal Reflux

Hungary, Austria, Germany, Poland
AstraZeneca

Active, not recruiting

Assessing Durvalumab and FLOT Chemotherapy in Resectable Gastric and Gastroesophageal Junction Cancer

Gastrointestinal Neoplasms | Esophagogastric Junction

Belgium, Denmark, Spain, United Kingdom, Canada, United States, Taiwan, Turkey, France, Germany, Korea, Republic of, Brazil, Hungary, Japan, Peru, Poland, Russian Federation, Netherlands, Chile, Argentina

Clinical Trials on Hepatic Function in Hungary

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