Clinical Trials on Hepatic Hemangioendothelioma in South Africa

Total 89 results

Pfizer

Completed

Pharmacokinetics Of Orally Administered Fx-1006A In Subjects With Hepatic Dysfunction

Mild Hepatic Dysfunction | Moderate Hepatic Dysfunction

South Africa
Convergence Pharmaceuticals

Completed

Efficacy and Safety of CNV2197944 Versus Placebo in Patients With Post-herpetic Neuralgia

Post-herpetic Neuralgia

South Africa
Novartis Pharmaceuticals

Completed

Pharmacokinetics and Safety of Single Subcutaneous Pasireotide (SOM230) in Subjects With Varying Degrees of Hepatic Function

Alcoholism | Hepatic Cirrhosis

Germany, Belgium, United States, South Africa
Cycle Pharmaceuticals Ltd.
Parexel

Completed

Assessment of Intra-subject Variability in the Bioavailability of Chlorpromazine Hydrochloride

Acute Intermittent Porphyria | Anti-Psychotic | Management of Manifestations of Psychotic Disorders | Treatment of Schizophrenia | Control Nausea and Vomiting | Relief of Restlessness and Apprehension Before Surgery | Adjunct in the Treatment of Tetanus | Control Manifestations of the Manic Type... and other conditions

South Africa
Pfizer

Completed

A Safety and Tolerability Study of CP-690,550 in Subjects With Hepatic Impairment and Normal Hepatic Function

Hepatic Insufficiency

United States
Pfizer

Completed

A Study To Compare Pharmacokinetics Of Dacomitinib (PF-00299804) Between Healthy Subjects And Subjects With Mild And Moderate Hepatic Impairment

Healthy | Otherwise Healthy Volunteers With Mild or Moderate Hepatic Dysfunction

United States
Novartis Pharmaceuticals

Completed

Single-dose Iloperidone Pharmacokinetics in Patients With Mild or Moderate Liver Disease, Compared to Healthy Volunteers

Hepatic Impairment

United States
Medical University of South Carolina
Emory University

Completed

Study to Evaluate if the Drug Vasopressin Protects the Kidneys for Patients Undergoing Liver Transplant

Liver Failure

United States
Ono Pharma USA Inc
Ono Pharmaceutical Co. Ltd

Completed

An Open-label, Single-dose, Intravenous Administration Study of ONO-2745/CNS 7056 in Subjects With Chronic Hepatic Impairment

Healthy | Hepatic Impairment

United States
Alnylam Pharmaceuticals

Completed

EXPLORE: A Natural History Study of Acute Hepatic Porphyria (AHP)

Acute Hepatic Porphyria

United States, Belgium, Bulgaria, France, Italy, Mexico, Spain, Taiwan, United Kingdom, Netherlands, Korea, Republic of, Switzerland, Czechia, Poland, Finland, Australia, Germany, Israel, Norway, South Africa
Mateon Therapeutics

Completed

Safety Study of Increasing Doses of Combretasatin A1 Diphosphate (OXi4503) as Monotherapy in Subjects With Hepatic Tumor Burden (OXi4503)

Neoplasm Metastasis

Australia
University of Athens

Recruiting

Vitamin C, Steroids, and Thiamine, and Cerebral Autoregulation and Functional Outcome in Septic Shock (CORVICTES-ΥΜ)

Septic Shock

Greece
University of Texas Southwestern Medical Center
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Terminated

Study of N-Acetylcysteine in Acute Liver Failure (ALF) (ONAC)

Acute Liver Failure | Fulminant Hepatic Failure

United States
William Lee
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Completed

A Multi-Center Trial to Study Acute Liver Failure in Adults (ALFSG)

Acute Liver Failure | Fulminant Hepatic Failure | Acute Liver Injury

United States, Canada
Bausch Health Americas, Inc.

Completed

Rifaximin Soluble Solid Dispersion (SSD) Tablets Plus Lactulose for the Treatment of Overt Hepatic Encephalopathy (OHE) (OHE)

Overt Hepatic Encephalopathy

United States
iN Therapeutics Co., Ltd.

Recruiting

A MAD Study to Evaluate the Safety, Tolerability and PK/PD of iN1011-N17 in Healthy Volunteers and PHN Patients.

Pain | Osteoarthritis | Chronic Pain | Neuropathic Pain | Post Herpetic Neuralgia

Australia
Medical University of South Carolina

Completed

Transradial Versus Transfemoral Arterial Access in Liver Cancer Embolization: Randomized Trial to Assess Patient Outcomes and Satisfaction (BEST ACCESS Trial). (ACCESS)

Hepatic Carcinoma | Chemoembolizaton | Transarterial Embolization

United States
Ocera Therapeutics, Inc.

Completed

Phase 2B Efficacy/Safety of Ornithine Phenylacetate in Hospitalized Cirrhotic Patients With Hepatic Encephalopathy (STOP-HE) (STOP-HE)

Hepatic Encephalopathy | Acute Episode of Overt Hepatic Encephalopathy

Belgium, Germany, Italy, Spain, United States, France, Austria, Russian Federation, Czechia, Australia, Hungary, Israel, Netherlands, Bulgaria, Estonia, Denmark, New Zealand
Ocera Therapeutics

Completed

AST-120 Used to Treat Mild Hepatic Encephalopathy (ASTUTE)

Mild Hepatic Encephalopathy

United States
The George Institute

Completed

Fludrocortisone Dose Response Relationship in Septic Shock - FluDReSS (FluDReSS)

Septic Shock | Critically Ill

Australia
University of Athens
Naval Hospital, Athens; General Hospital of Nikaia "Saint Panteleimon"

Recruiting

Vitamin C, Hydrocortisone and Thiamine for Septic Shock (CORVICTES)

Shock, Septic

Greece
Bausch Health Americas, Inc.

Active, not recruiting

Study to Assess Rifaximin Soluble Solid Dispersion (SSD) for the Delay of Encephalopathy Decompensation in Cirrhosis (RED-C-3131)

Hepatic Encephalopathy

United States, Australia, Canada, Puerto Rico
Albert Einstein Healthcare Network
Patient-Centered Outcomes Research Institute

Recruiting

Introducing Palliative Care (PC) Within the Treatment of End Stage Liver Disease (ESLD) (PAL-LIVER)

End Stage Liver Disease

United States
The George Institute for Global Health, Australia

Completed

Days Alive and Out of Hospital for Patients With Sepsis

Sepsis | Septic Shock

Australia
Axcella Health, Inc

Terminated

Efficacy and Safety of AXA1665 in Cirrhotic Subjects With Prior Overt Hepatic Encephalopathy (EMMPOWER)

Hepatic Encephalopathy

Spain, United States, Canada, Italy, Hungary, Poland, United Kingdom
Bausch Health Americas, Inc.

Active, not recruiting

Study to Assess Rifaximin Soluble Solid Dispersion (SSD) for the Delay of Encephalopathy Decompensation in Cirrhosis (RED-C-3132)

Hepatic Encephalopathy

United States, Australia, Belgium, Bulgaria, Canada, France, Germany, Hungary, India, Italy, Korea, Republic of, Mongolia, New Zealand, Poland, Puerto Rico, Spain, United Kingdom
Lateral Pharma Pty Ltd

Completed

Oral LAT8881 in Neuropathic Pain

Neuropathic Pain | Diabetic Peripheral Neuropathy (DPN) | Post Herpetic Neuralgia (PHN)

Australia, United Kingdom
Medical University of South Carolina

Completed

Safety and Efficacy of ProQuad® in Children 6-24 Month Being Evaluated for Solid Organ Transplant (ProQuad®)

RENAL INSUFFICIENCY, CHRONIC | LIVER FAILURE, ACUTE | HEART DISEASE

United States
AstraZeneca

Completed

A Study to Prevent Rebleeding After Initial Successful Primary Endoscopic Haemostasis of a Bleeding Peptic Ulcer

Gastrointestinal Hemorrhage

Sweden, Russian Federation, South Africa, Spain, Turkey, United Kingdom, Germany, Romania, Finland, Norway, Hong Kong, Austria, Denmark, Netherlands, Greece, France
University of Texas Southwestern Medical Center
Medical University of South Carolina; National Institute of Diabetes and Digestive... and other collaborators

Completed

13C-Methacetin Breath Test for the Prediction of Outcome in in ALI or ALF (ALFSG-MBT)

Acute Liver Failure

United States
National Cancer Institute (NCI)
Glaxosmithkline Biologicals S.A.

Terminated

Dabrafenib in Treating Patients With Solid Tumors and Kidney or Liver Dysfunction

Renal Failure | Solid Neoplasm | BRAF Gene Mutation | Hepatic Complication

United States, Canada
The George Institute
National Health and Medical Research Council, Australia; Australian and New...

Completed

ADjunctive coRticosteroid trEatment iN criticAlly ilL Patients With Septic Shock (ADRENAL)

Septic Shock

Australia, Denmark, Saudi Arabia, New Zealand, United Kingdom
National Institute of Diabetes and Digestive and...
University of Texas Southwestern Medical Center

Completed

Randomized Study of Acetylcysteine in Patients With Acute Liver Failure Not Caused by Acetaminophen

Acute Liver Failure

United States
William Lee
Medical University of South Carolina; National Institute of Diabetes and Digestive... and other collaborators

Completed

Safety Study of Ornithine Phenylacetate to Treat Patients With Acute Liver Failure/Severe Acute Liver Injury (STOP-ALF)

Acute Liver Failure | Acute Liver Injury

United States
Wentworth Area Health Services
Abbott

Unknown

Levosimendan Versus Dobutamine in Shock Patients

Septic Shock | Cardiogenic Shock

Australia
University of Alabama at Birmingham
National Institute of Nursing Research (NINR)

Completed

A Culturally-Based Palliative Care Tele-consult Program for Rural Southern Elders

Stroke | Sepsis | Cancer | Pulmonary Disease | Hepatic Disease | Cardiac Disease | Renal Disease | Neuro-Degenerative Disease

United States
Takeda

Completed

Comparison of the Classical Healing Concept With the Complete Remission Concept After Treatment With Pantoprazole in Adult Patients With Erosive GERD (Gastroesophageal Reflux Disease) (BY1023/M3-342)

Gastroesophageal Reflux Disease

Germany, Poland, Brazil, South Africa
Jazz Pharmaceuticals

Completed

Defibrotide for Patients With Hepatic Veno-occlusive Disease: A Treatment IND Study (Treatment IND)

Hepatic Veno-Occlusive Disease

United States
Gianluca Costa

Recruiting

Laparoscopic Versus Open Repair of Peptic Ulcer Perforation (LOREPUP)

Emergencies | Surgery | Peptic Ulcer Perforation

Italy
University of Washington
National Institute of Nursing Research (NINR)

Completed

Improving Clinician Communication Skills (ICCS) (ICCS)

End Stage Liver Disease | Chronic Obstructive Pulmonary Disease (COPD) | Advanced Cancer | Congestive Heart Failure | Restrictive Lung Disease

United States
Australian and New Zealand Intensive Care Research...

Recruiting

Australasian Resuscitation In Sepsis Evaluation: FLUid or Vasopressors In Emergency Department Sepsis (ARISE FLUIDS)

Shock, Septic

Australia
Ironwood Pharmaceuticals, Inc.

Completed

Ph2a Study to Evaluate IW-3718 in Patients With Gastroesophageal Reflux Not Completely Responsive to Proton Pump Inhibitors

Gastroesophageal Reflux

United States
Pfizer's Upjohn has merged with Mylan to form Viatris...

Completed

Safety And Efficacy Study Of Once Daily Controlled Release Pregabalin In The Treatment Of Patients With Postherpetic Neuralgia

Post Herpetic Neuralgia

United States, Colombia, South Africa, Hong Kong, Ukraine, Bulgaria, Croatia, India, Sweden, Czechia, Denmark, Germany, Poland, Russian Federation, Serbia, Slovakia, Taiwan
AstraZeneca

Completed

A Study to Compare the Efficacy and Safety of 2 Dosing Regimens of IV Infusions of AZD9773 (CytoFab™) With Placebo in Adult Patients With Severe Sepsis and/or Septic Shock

Septic Shock | Severe Sepsis

Czech Republic, France, Spain, Finland, Canada, Australia, Belgium
Spectral Diagnostics (US) Inc.

Recruiting

Safety and Efficacy of Polymyxin B Hemoperfusion (PMX) for Endotoxemic Septic Shock in a Randomized, Open-Label Study (TIGRIS)

Septic Shock | Endotoxemia

United States
Jazz Pharmaceuticals

Completed

Study Comparing Efficacy and Safety of Defibrotide vs Best Supportive Care in the Prevention of Hepatic Veno-Occlusive Disease in Adult and Pediatric Patients

Veno-occlusive Disease

United States, Spain, Belgium, Australia, Italy, Israel, Japan, Korea, Republic of, France, Canada, United Kingdom, Germany, New Zealand, Turkey
NeurAxon Inc.

Completed

Efficacy, Tolerability, and Safety of NXN-462 in Patients With Post-Herpetic Neuralgia

Post Herpetic Neuralgia

United States, Canada
Murdoch Childrens Research Institute

Recruiting

BonE and Joint Infections - Simplifying Treatment in Children Trial (BEST)

Osteomyelitis | Septic Arthritis | Bone Infection | Bone and Joint Infection

New Zealand, Australia
Takeda

Completed

Efficacy and Safety of Dexlansoprazole MR and Lansoprazole on Healing of Erosive Esophagitis

Esophagitis, Peptic | Esophagitis, Reflux

United States, Poland, Bulgaria, India, Canada, Peru, Russian Federation, Australia, New Zealand, Czech Republic, Slovakia, South Africa, Latvia, Lithuania, Colombia, Germany
Disc Medicine, Inc

Enrolling by invitation

Open-Label, Long-Term Extension Study to Investigate the Safety, Tolerability, and Efficacy of DISC-1459 (Bitopertin) in Participants With EPP

Erythropoietic Protoporphyria

United States, Australia

Clinical Trials on Hepatic Hemangioendothelioma in South Africa

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