Clinical Trials on Hereditary Corneal Dystrophy in Italy

Total 343 results

BioMarin Pharmaceutical

Terminated

Phase IIb Study of PRO045 in Subjects With Duchenne Muscular Dystrophy

Duchenne Muscular Dystrophy

Belgium, Netherlands, France, United Kingdom, Italy
BioMarin Pharmaceutical

Terminated

A Phase I/II Study of BMN053 in Subjects With Duchenne Muscular Dystrophy (DMD)

Duchenne Muscular Dystrophy

United Kingdom, Italy, Belgium, Netherlands, France
University Hospital, Catania

Unknown

Hereditary AngioEdema, Neurobiology and Psychopathology (HAENP)

Depression | Anxiety | Hereditary AngioEdema

Italy
NS Pharma, Inc.
Nippon Shinyaku Co., Ltd.

Completed

Study to Assess the Safety, Tolerability, and Efficacy of Viltolarsen in Ambulant and Non-Ambulant Boys With DMD (Galactic53)

Duchenne Muscular Dystrophy

Spain, United States, Russian Federation, Italy, China, Turkey
Cooperative International Neuromuscular Research...
Washington University School of Medicine; Children's National Research Institute and other collaborators

Completed

Comparative Study of Clinical Endpoint in DMD: Handheld Myometry (HHM) Versus CINRG Quantitative Measurement System (CQMS)

Duchenne Muscular Dystrophy

United States, Australia, Italy
Bambino Gesù Hospital and Research Institute

Completed

Cornea Ectasia Excimer Laser Treatment

Corneal Ectasia

Italy
Virginia Commonwealth University

Recruiting

DMCRN-02-001: Assessing Pediatric Endpoints in DM1 (ASPIRE-DM1)

Congenital Myotonic Dystrophy | Childhood Myotonic Dystrophy | CDM | CHDM

United States, Italy
Fondazione Policlinico Universitario Agostino Gemelli...

Recruiting

Multimodal Imaging in Vitreo-retinal Surgery and Macular Dystrophies (MICAI)

Retinal Detachment | Epiretinal Membrane | Macular Holes | Macular Dystrophies

Italy
Shire

Completed

Subcutaneous Treatment With Icatibant for Acute Attacks of Hereditary Angioedema (HAE) (FAST2)

Hereditary Angioedema

Italy
Istituti Clinici Scientifici Maugeri SpA

Completed

Autonomic Nervous System Profile in Hereditary Angioedema (ANS-HAE)

Hereditary Angioedema

Italy
Istituto Ortopedico Rizzoli

Completed

Height, Ulnar Length and Forearm Function in Multiple Hereditary Exostoses

Exostoses, Multiple Hereditary

Italy
Wave Life Sciences Ltd.

Completed

Safety and Tolerability of WVE-210201 in Patients With Duchenne Muscular Dystrophy

Duchenne Muscular Dystrophy

Belgium, United Kingdom, France, United States, Italy, Canada, Netherlands
Dyne Therapeutics

Recruiting

Safety, Tolerability, Pharmacodynamic, Efficacy, and Pharmacokinetic Study of DYNE-101 in Participants With Myotonic Dystrophy Type 1 (ACHIEVE)

Myotonic Dystrophy Type 1 (DM1)

United Kingdom, France, Netherlands, Italy, Germany, New Zealand
Istituto Internazionale di Ricerca e Formazione...

Recruiting

Deep Anterior Lamellar Keratoplasty Using Dehydrated Versus Standard Organ Culture Stored Donor Corneas

Keratoconus

Italy
Fondazione Policlinico Universitario Agostino Gemelli...

Completed

Counseling Intervention in Hereditary Hemorrhagic Telangiectasia in the COVID Era.

Hereditary Hemorrhagic Telangiectasia

Italy
Istituti Clinici Scientifici Maugeri SpA

Completed

Social Evaluated Cold Pressor Test in Hereditary Angioedema Patients (FROSEN)

Hereditary Angioedema

Italy
Associazione Italiana per lo Studio del Pancreas
General and Pancreatic Surgery Unit, University of Verona; Fondazione Valsecchi and other collaborators

Recruiting

Familial Pancreatic Cancer PROPHilation Program in Italy (PROPH-ITA)

Candidates for Hereditary Pancreatic Cancer Testing

Italy
Santhera Pharmaceuticals
European Vision Institute Clinical Research Network

Completed

Leber Hereditary Optic Neuropathy (LHON) Historical Case Record Survey

Leber Hereditary Optic Neuropathy (LHON)

Belgium, France, Denmark, Italy, Slovenia
Virginia Commonwealth University
University of Western Ontario, Canada, Children's Health Research Institute; Fondazione Serena Onlus - Centro Clinico NeMO Milano

Recruiting

Trial Readiness and Endpoint Assessment in Congenital Myotonic Dystrophy (TREAT-CDM)

Congenital Myotonic Dystrophy

United States, Italy, Canada
Holostem Terapie Avanzate s.r.l.
Cromsource

Completed

Follow-up Study After ACLSCT for Restoration of Corneal Epithelium in Patients With LSCD Due to Ocular Burns (HOLOCORE-FU)

Limbal Stem Cell Deficiency Due to Ocular Burn

Italy
ML Bio Solutions, Inc.

Recruiting

Study to Evaluate the Efficacy and Safety of BBP-418 (Ribitol) in Patients With Limb Girdle Muscular Dystrophy 2I (LGMD2I) (Fortify)

Limb-Girdle Muscular Dystrophy Type 2I (LGMD2I)

United States, Netherlands, United Kingdom, Denmark, Australia, Italy, Norway
PTC Therapeutics

Completed

Study of Ataluren for Previously Treated Participants With Nonsense Mutation Duchenne/Becker Muscular Dystrophy (nmDBMD) in Europe, Israel, Australia, and Canada

Duchenne Muscular Dystrophy | Becker Muscular Dystrophy | Dystrophinopathy

United Kingdom, Canada, Germany, Spain, Sweden, Italy, Australia, Belgium, France, Israel
Fulcrum Therapeutics

Active, not recruiting

Efficacy and Safety of Losmapimod in Treating Participants With Facioscapulohumeral Muscular Dystrophy (FSHD) (REACH)

Facioscapulohumeral Muscular Dystrophy (FSHD)

United States, Spain, Italy, Denmark, Canada, Germany, France, Netherlands, United Kingdom
IRCCS Fondazione Stella Maris

Completed

Trehalose Administration in Subjects With Spastic Paraplegia 11 (3AL-SPG11) (3AL-SPG11)

Hereditary Spastic Paraplegia | Spastic Paraplegia Type 11

Italy
Fondazione IRCCS Ca' Granda, Ospedale Maggiore...

Completed

HORMONES IN VERNAL KERATOCONJUNCTIVITIS (HOR-VKC-2020)

Conjunctivitis, Vernal

Italy
SIFI SpA

Completed

Efficacy of Topical 0.2% Xanthan Gum in Patients With Dry Eye

Dry Eye

Italy
Dyne Therapeutics

Recruiting

Safety, Tolerability, Pharmacodynamic, Efficacy, and Pharmacokinetic Study of DYNE-251 in Participants With Duchenne Muscular Dystrophy Amenable to Exon 51 Skipping (DELIVER)

Duchenne Muscular Dystrophy (DMD)

United States, Belgium, Canada, United Kingdom, Australia, Spain, Italy
University Hospital of Ferrara

Unknown

Effects of Proprioceptive Stimulation Under Visual Feedback in Patient With CRPS

Complex Regional Pain Syndromes

Italy
Francesco Bandello

Recruiting

Evaluation of Dry Eye Disease's Signs in Patients Who Were Administered Intravitreal Anti-VEGF Injections (DRYEYE-IVT)

Dry Eye Syndromes

Italy
Italfarmaco
Fortrea

Recruiting

Efficacy, Safety and Tolerability of Givinostat in Non-ambulant Patients With Duchenne Muscular Dystrophy (ULYSSES)

Duchenne Muscular Dystrophy

Belgium, Netherlands, Canada, Italy, France, Germany, United Kingdom
Mallinckrodt ARD LLC

Terminated

A Study to Assess the Efficacy and Safety of MNK-1411 in Duchenne Muscular Dystrophy (BRAVE)

Muscular Dystrophy, Duchenne

Spain, Bulgaria, Italy, United States, Mexico, Israel, Serbia, Turkey
GenSight Biologics

Completed

RESCUE and REVERSE Long-term Follow-up (RESTORE)

Leber Hereditary Optic Neuropathy

United States, France, Italy, United Kingdom, Germany
Azienda Ospedaliera Universitaria Mater Domini,...

Recruiting

Efficacy of Low-Level Light Therapy in Reducing Dry Eye in Patients Undergoing Cataract Surgery

Dry Eye

Italy
Campus Bio-Medico University
University of Padova; University of Genova

Completed

Cyclosporin A Eye Drop Treatment in Vernal Keratoconjunctivitis

Vernal Keratoconjunctivitis

Italy
BioMarin Pharmaceutical

Terminated

A Prospective Natural History Study of Progression of Subjects With Duchenne Muscular Dystrophy.

Duchenne Muscular Dystrophy

United States, Netherlands, Belgium, Germany, Argentina, Brazil, France, Italy, Sweden, Turkey
Campus Bio-Medico University
University of Padova; University of Genova

Completed

Lactobacillus Rhamnosus GG Oral Treatment Efficacy on Vernal Keratoconjunctivitis Treatment

Vernal Keratoconjunctivitis

Italy
IRCCS Eugenio Medea

Completed

Assessment of the Psychophysical State During Rehabilitation Treatment With Lokomat

Cerebral Palsy | Acquired Brain Injury | Hereditary Spastic Paraplegia

Italy
Dompé Farmaceutici S.p.A

Completed

Evaluation of Safety and Efficacy of rhNGF in Patients With Stage 2 and 3 Neurotrophic Keratitis. (REPARO)

Keratitis | Neurotrophic Keratitis | Corneal Ulcer

Germany, Italy, France, Poland, Spain, United Kingdom
Dompé Farmaceutici S.p.A

Completed

Tolerability, Safety and Efficacy of Lubricin (150 µg/ml) Eye Drops Versus Sodium Hyaluronate (HA) 0.18% Eye Drops in Patients With Moderate Dry Eye (DE)

Dry Eye Syndrome

Italy
ProQR Therapeutics

Recruiting

An Open-label, Dose Escalation and Double-masked, Randomized, Controlled Trial Evaluating Safety and Tolerability of Sepofarsen in Children (<8 Years of Age) With LCA10 Caused by Mutations in the CEP290 Gene. (BRIGHTEN)

Eye Diseases | Neurologic Manifestations | Retinal Degeneration | Retinal Dystrophies | Sensation Disorders | Vision Disorders | Blindness | Leber Congenital Amaurosis | Leber Congenital Amaurosis 10 | Retinal Disease | Eye Disorders Congenital

Belgium, Brazil, Canada, Germany, Italy, Netherlands, United Kingdom
Istituto Ortopedico Rizzoli

Recruiting

Treatment of Upper Cluneal Nerve Entrapment Syndrome for Reduction of Low Back Pain

Superior Cluneal Nerve Entrapment

Italy
Pharvaris Netherlands B.V.

Active, not recruiting

Dose-ranging Study of Oral PHA-022121 for Prophylaxis Against Angioedema Attacks in Patients With Hereditary Angioedema Type I or Type II (HAE CHAPTER-1)

Hereditary Angioedema | Hereditary Angioedema Type I | Hereditary Angioedema Type II | Hereditary Angioedema Types I and II | Hereditary Angioedema Attack | Hereditary Angioedema With C1 Esterase Inhibitor Deficiency | Hereditary Angioedema - Type 1 | Hereditary Angioedema - Type 2 | C1 Esterase Inhibitor... and other conditions

United States, Poland, Germany, Austria, Bulgaria, Canada, Ireland, Italy, United Kingdom
Cooperative International Neuromuscular Research...

Unknown

Becker Muscular Dystrophy - A Natural History Study to Predict Efficacy of Exon Skipping

Becker Muscular Dystrophy

United States, Canada, Italy, United Kingdom
Wave Life Sciences Ltd.

Terminated

Efficacy and Safety Study of WVE-210201 (Suvodirsen) With Open-label Extension in Ambulatory Patients With Duchenne Muscular Dystrophy (DYSTANCE 51)

Duchenne Muscular Dystrophy

United States, Belgium, United Kingdom, Czechia, Canada, France, Italy, Sweden
Santhera Pharmaceuticals

Terminated

A Phase III Double-blind Study With Idebenone in Patients With Duchenne Muscular Dystrophy (DMD) Taking Glucocorticoid Steroids (SIDEROS)

Duchenne Muscular Dystrophy (DMD)

United States, Spain, Netherlands, Sweden, Germany, France, Belgium, United Kingdom, Italy, Ireland, Switzerland, Austria, Bulgaria, Hungary, Israel
Sarepta Therapeutics, Inc.

Active, not recruiting

Two-Part Study for Dose Determination of Vesleteplirsen (SRP-5051) (Part A), Then Dose Efficacy (Part B) in Participants With Duchenne Muscular Dystrophy Amenable to Exon 51-Skipping Treatment (MOMENTUM)

Duchenne Muscular Dystrophy

United States, Belgium, Spain, United Kingdom, Netherlands, Germany, Canada, Italy
Centro Oculistico Borroni

Completed

Quantum Molecular Resonance Electrotherapy in Severe Dry Eye Disease (QMR)

Dry Eye

Italy
PTC Therapeutics

Completed

Phase 2B Study of PTC124 (Ataluren) in Duchenne/Becker Muscular Dystrophy (DMD/BMD)

Duchenne Muscular Dystrophy | Becker Muscular Dystrophy

United States, Germany, Spain, Sweden, Canada, Italy, Australia, Belgium, France, Israel, United Kingdom
University of Milan

Completed

Management of Dry Eye Disease After Cataract Surgery With Topical Hyaluronic Acid and Gingko Biloba

Dry Eye Syndromes

Italy
University of Naples

Completed

Efficacy of Riboflavin-Enhanced Hyaluronic Acid Eye Drops in Treating Dry Eye Disease

Dry Eye Disease

Italy

Clinical Trials on Hereditary Corneal Dystrophy in Italy

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