Clinical Trials on Hereditary Cancer

Total 53872 results

Stephen E. Goldstone

Unknown

A Safety and Efficacy Trial of Circumferential Anal Canal Radiofrequency Ablation for High-Grade Anal Intraepithelial Neoplasia Using the BARRX™ Anorectal Wand

Anal Cancer | Human Papillomavirus Infection | Human Papilloma Virus | HSIL, High Grade Squamous Intraepithelial Lesions | HPV-Related Squamous Cell Carcinoma | Ain III

United States
Eli Lilly and Company

Completed

A Phase 1 Study in Participants With Advanced Cancer

Carcinoma, Non-Small-Cell Lung | Advanced Cancer | Anal Squamous Cell Carcinoma | Squamous Cell Carcinoma | Carcinoma, Squamous Cell of Head and Neck | Lung Squamous Cell Carcinoma Stage IV

United States
Radiation Therapy Oncology Group
National Cancer Institute (NCI); NRG Oncology

Withdrawn

Radiation Therapy and Cisplatin With or Without Surgery in Treating Patients With Stage III-IV Oropharyngeal Cancer

Tongue Cancer | Stage III Squamous Cell Carcinoma of the Oropharynx | Stage IVA Squamous Cell Carcinoma of the Oropharynx

United States
Fujian Medical University Union Hospital

Recruiting

Multicenter Clinical Trial on the Effectiveness and Safety of Instillation of BCG and Alternative BCG Protocols for Intermediate and High-risk Non-muscle Invasive Bladder Cancer

Urinary Bladder Neoplasms | Treatment Outcome | Neoplasm Recurrence, Local | Multicenter Study | Immunotherapy, Active | BCG Vaccine

China
Centre Hospitalier de Saint-Denis

Recruiting

The Value of HPV Testing for Cervical Cancer Screening in Women Living With HIV (PAPILLO-VIH) (PAPILLO-VIH)

HIV Seropositivity

France
Centre Hospitalier Metropole Savoie

Recruiting

Prospective Study of Detection of Sarcopenia in Clinical Practice for Patient With Ovarian or Endometrial Cancer (SARCO-GYN)

Ovarian Neoplasms | Sarcopenia

France
Baylor College of Medicine
The University of Texas Health Science Center, Houston; University of Texas... and other collaborators

Recruiting

Survivorship Care for Women Living With Ovarian Cancer: (POSTCARE-O) (POSTCARE-O)

Quality of Life | Depressive Symptoms | Ovarian Neoplasm

United States
Xiaoxiang Chen

Recruiting

Anlotinib Combined With Dose-reduced Olaparib in Patients With Platinum-Sensitive Recurrent Ovarian Cancer (ANLOLA)

Neoplasms | Neoplasms by Histologic Type | Urogenital Neoplasms | Neoplasms by Site | Carcinoma | Neoplasms, Glandular and Epithelial | Genital Neoplasms, Female | Ovarian Diseases | Adnexal Diseases | Carcinoma, Ovarian Epithelial | Ovarian Cancer | Angiogenesis | Genital Diseases, Female | Antineoplastic Agents | BRCA1... and other conditions

China
National Cancer Institute (NCI)
NCIC Clinical Trials Group; Cancer and Leukemia Group B; North Central Cancer... and other collaborators

Active, not recruiting

Chemotherapy With or Without Bevacizumab in Treating Patients With Stage IB, Stage II, or Stage IIIA Non-small Cell Lung Cancer That Was Removed By Surgery

Stage IB Lung Non-Small Cell Carcinoma AJCC v7 | Stage IIA Lung Non-Small Cell Carcinoma AJCC v7 | Stage IIB Lung Non-Small Cell Carcinoma AJCC v7 | Stage IIIA Lung Non-Small Cell Cancer AJCC v7

United States, Canada, Ireland, Peru, South Africa
University Medical Center Groningen
Genentech, Inc.; Amsterdam UMC, location VUmc

Completed

89Zr-MMOT PET Imaging in Pancreatic and Ovarian Cancer Patients (MMOT)

Digestive System Diseases | Ovarian Diseases | Adnexal Diseases | Digestive System Neoplasms | Pancreatic Neoplasms | Ovarian Neoplasms | Pancreatic Diseases

Netherlands
M.D. Anderson Cancer Center
National Cancer Institute (NCI); Janssen Research & Development, LLC

Active, not recruiting

Daratumumab in Treating Patients With Muscle Invasive Bladder Cancer or Metastatic Kidney Cancer

Clear Cell Renal Cell Carcinoma | Stage IV Renal Cell Cancer AJCC v8 | Bladder Urothelial Carcinoma | Metastatic Kidney Carcinoma | Malignant Urinary System Neoplasm

United States
Daping Hospital and the Research Institute of Surgery...

Active, not recruiting

PPIO-007 Correlation Analysis of Type II Diabetes Mellitus on Short-term and Long-term Outcomes of Patients With Esophageal Squamous Cell Cancer Undergoing Minimally Invasive Esophagectomy

Surgery | Esophageal Squamous Cell Carcinoma

China
Hacettepe University

Completed

Comparison of the Effectiveness of Different Conservative Treatment Protocols in Postprostatectomy Urinary Incontinence

Urinary Incontinence | Prostate Cancer | Urinary Incontinence,Stress | Urinary Incontinence Due to Urethral Sphincter Incompetence

Turkey
Intuitive Surgical

Active, not recruiting

SP Thoracic IDE Study

Thymoma | Myasthenia Gravis | Primary Lung Cancer | Benign Lung Disease

United States
Istanbul University - Cerrahpasa (IUC)
Health Institutes of Turkey

Completed

Clinic or Self-Sampling for Cervical Cancer Screening

Cervical Cancer | HPV Infection

Turkey
Transgene

Active, not recruiting

A Trial Evaluating TG4050 in Ovarian Carcinoma.

Fallopian Tube Cancer | Peritoneal Carcinoma | Ovarian Carcinoma

United States, France
Abramson Cancer Center at Penn Medicine
National Heart, Lung, and Blood Institute (NHLBI)

Active, not recruiting

Pilot Study of an NTproBNP Guided Strategy of Cardioprotection (NTproBNP-Guide)

Heart Failure | Lymphoma | Breast Cancer | Cardiomyopathies | Cardiotoxicity | Toxicity Due to Chemotherapy

United States
University of California, Davis
National Cancer Institute (NCI); Merck Sharp & Dohme LLC; Novartis

Active, not recruiting

Pembrolizumab and Trametinib in Treating Patients With Stage IV Non-Small Cell Lung Cancer and KRAS Gene Mutations

KRAS Gene Mutation | Stage IV Non-Small Cell Lung Cancer AJCC v7 | Recurrent Non-Squamous Non-Small Cell Lung Carcinoma | Metastatic Non-Squamous Non-Small Cell Lung Carcinoma

United States
Tanta University

Enrolling by invitation

Role of Silymarin in Chemotherapy Toxicity and Cognition Improvement in Breast Cancer Patients

Breast Cancer | Cognitive Impairment | Peripheral Neuropathy | Cardiac Toxicities | Hepatic Toxicity

Egypt
Rachel Miller
Office of US Army Medical Research and Material Command

Completed

Chemotherapy-Induced Cognitive Impairment in Ovarian Cancer Patients

Chemotherapy-induced Cognitive Impairment

United States
Masonic Cancer Center, University of Minnesota

Terminated

Allogeneic Bone Marrow Transplantation Using Less Intensive Therapy

Lymphoma | Kidney Cancer | Myelodysplastic Syndromes | Leukemia | Multiple Myeloma | Plasma Cell Neoplasm

United States
St. James's Hospital, Ireland

Completed

Neoadjuvant Therapy for Esophageal Cancer and Cardiopulmonary Physiology

Pneumonia | Adenocarcinoma | Respiratory Failure | Esophageal Cancer | Pulmonary Fibrosis | Surgery | Chemotherapy Effect | Radiation Toxicity | Squamous Cell Carcinoma | Radiation Pneumonitis | Radiation Fibrosis

Ireland
Brigham and Women's Hospital
CVS Caremark

Completed

Robust Evaluation to Measure Improvements in Nonadherence From Low-cost Devices (REMIND)

Depression | Epilepsy | Cardiovascular Disease | Diabetes | Breast Cancer | Parkinson's Disease | Mental Health Disorder | Prostatic Hypertrophy, Benign

United States
National Cancer Institute (NCI)

Completed

Green Tea Extract in Preventing Cervical Cancer in Patients With Human Papillomavirus and Low-Grade Cervical Intraepithelial Neoplasia

Cervical Cancer | Human Papilloma Virus Infection | Cervical Intraepithelial Neoplasia Grade 1

United States
Pfizer

Completed

A Multicenter Phase 2 Study of CI-1040 in Patients With Advanced Nonsmall-Cell Lung, Breast, Colon and Pancreatic Cancer

Breast Neoplasms | Carcinoma, Non-Small-Cell Lung | Colorectal Neoplasms | Pancreatic Neoplasms

United States
University Hospital, Clermont-Ferrand

Unknown

Low-dose CT Angiography in the Detection of Acute Pulmonary Embolism: Validation in an Obese Population

Obesity | Pulmonary Embolism | CT Scanner

France
The University of New South Wales
National Health and Medical Research Council, Australia; Novo Nordisk A/S; Sydney...

Completed

Rosiglitazone and Insulin in T1DM Adolescents

Type 1 Diabetes | Puberty: >Tanner 2 Breast Development or Testis >4ml

Australia
VA Office of Research and Development

Completed

Group CBT for Aggression in Veterans (CBT-A)

Anger | Aggression | Posttraumatic Stress Disorder

United States
Rehabilitation and Research Centre for Torture...
Kosova Rehabilitation Centre for Torture Victims

Completed

Effectiveness of Combined Intervention Approaches in the Treatment of Affective Disorders and Chronic Pain in War Victims

Anger | Depression | PTSD | Chronic Pain | Anxiety

Kosovo
Incyte Corporation

Active, not recruiting

Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of INCB099318 in Participants With Advanced Solid Tumors

Cervical Cancer | Nasopharyngeal Carcinoma | Advanced Solid Tumors | Mesothelioma | Small-cell Lung Cancer | Esophageal Squamous Cell Carcinoma | Merkel Cell Carcinoma | Sarcomatoid Renal Cell Carcinoma | Anal Carcinoma | Cutaneous Squamous Cell Carcinoma | MSI-H/dMMR Tumors | PD-L1 Amplified Tumor (9p24.1) | Urothelial... and other conditions

Finland, United States, United Kingdom, Belgium, Sweden, Denmark, Norway
University of California, San Francisco
National Institute of Dental and Craniofacial Research (NIDCR)

Not yet recruiting

People Living With HIV, Oral and Oropharyngeal Cancer, and Health Equity

HIV Infections | Oropharyngeal Squamous Cell Carcinoma | Oral Squamous Cell Carcinoma

United States
Maastricht University Medical Center

Recruiting

Complications and Recurrences After Mohs Micrographic Surgery and Slow Mohs

Recurrence | Complication of Surgical Procedure | Skin Cancer | Recurrent Disease | Complication | Complication,Postoperative | Lentigo Maligna Melanoma | Basal Cell Carcinoma | Cutaneous Squamous Cell Carcinoma | Lentigo Maligna

Netherlands
M.D. Anderson Cancer Center

Recruiting

Early Assessment of Ovarian Cancer Aggressiveness by Metabolic Imaging

Ovarian Cancer

United States
AstraZeneca

Recruiting

Phase I/IIa Study for AZD5335 as Monotherapy and in Combination With Anti-cancer Agents in Participants With Solid Tumors (FONTANA)

Ovarian Cancer | Lung Adenocarcinoma

United States, China, Spain, Canada, Australia, Taiwan, Israel, Japan, United Kingdom
University of Aarhus
Aarhus University Hospital; Bandim Health Project; Universiteit Antwerpen; Randers...

Recruiting

Self-collected Vaginal and Urine Samples in HIV-positive Women

HIV Infections | Cervical Cancer | HPV-Related Cervical Carcinoma | Coinfection, HIV

Guinea-Bissau
Nova Scotia Health Authority
Dalhousie University

Recruiting

Prehabilitation for Ovarian Cancer Patients

Ovarian Cancer | Frailty | Exercise | Enhanced Recovery After Surgery | Surgical Complication | Prehabilitation | Treatment Outcomes

Canada
M.D. Anderson Cancer Center

Recruiting

Radiofrequency Ablation for the Treatment of Benign or Low Risk Thyroid Nodule

Recurrent Thyroid Gland Carcinoma | Thyroid Gland Nodule | Thyroid Gland Papillary Carcinoma | Benign Thyroid Gland Neoplasm | Thyroid Gland Follicular Tumor of Uncertain Malignant Potential

United States
Universitair Ziekenhuis Brussel

Recruiting

Study of 68GaNOTA-Anti-MMR-VHH2 in Oncological Lesions, Cardiovascular Atherosclerosis, Syndrome With Abnormal Immune Activation and sarcoïdosis (MITRAS)

Cancer | Carotid Stenosis | Non Hodgkin Lymphoma | Sarcoidosis | Cardiac Sarcoidosis | Hodgkin Lymphoma, Adult | Atherosclerosis of Artery | HLH | Solid Malignancy Located in the Head and Neck

Belgium
Pfizer

Recruiting

Study to Test the Safety and Tolerability of PF-07220060 in Participants With Advance Solid Tumors (CDK4i)

Breast Neoplasms | Prostate Cancer | Adenocarcinoma of Lung | Solid Tumors | Liposarcoma | CRC

China, United States, United Kingdom, Mexico, Czechia, Japan, Slovakia, Argentina
Sun Yat-sen University
Shenzhen Nanshan Center for Chronic Disease Control

Recruiting

Nanshan Elderly Cohort Study (NECS)

Cardiovascular Diseases | Stroke | Hypertension | Obesity | Cancer | Type 2 Diabetes Mellitus | Death | Metabolic Syndrome | Chronic Kidney Disease | Sarcopenia

China
Dana-Farber Cancer Institute
National Institutes of Health (NIH); Candel Therapeutics, Inc.

Recruiting

A Study of the Treatment of Recurrent Malignant Glioma With rQNestin34.5v.2 (rQNestin)

Glioma | Glioblastoma | Astrocytoma | Malignant Glioma of Brain | Brain Cancer | Brain Tumor | Glioblastoma Multiforme | Ependymoma | Ganglioglioma | Oligodendroglioma | Malignant Astrocytoma | Anaplastic Oligodendroglioma of Brain (Diagnosis) | Mixed Oligo-Astrocytoma | Pylocytic/Pylomyxoid Astrocytoma

United States
Sidney Kimmel Cancer Center at Thomas Jefferson...
National Cancer Institute (NCI)

Recruiting

High Volume Washing of the Abdomen in Increasing Survival After Surgery in Patients With Pancreatic Cancer That Can Be Removed by Surgery

Pancreatic Adenocarcinoma | Cholangiocarcinoma | Pancreatic Ductal Adenocarcinoma | Acinar Cell Carcinoma | Ampulla of Vater Adenocarcinoma | Periampullary Adenocarcinoma | Duodenal Adenocarcinoma | Pancreatic Intraductal Papillary Mucinous Neoplasm

United States
National Cancer Institute (NCI)

Active, not recruiting

Gemcitabine Hydrochloride Alone or With M6620 in Treating Patients With Recurrent Ovarian, Primary Peritoneal, or Fallopian Tube Cancer

Recurrent Fallopian Tube Carcinoma | Recurrent Ovarian Carcinoma | Recurrent Primary Peritoneal Carcinoma | Ovarian Serous Tumor

United States
Teal Health, Inc.

Enrolling by invitation

SELF-CERV Pivotal Study: SELF-Collection for CERVical Cancer Screening

HPV Infection | HPV 16 Infection | Hpv | High Risk HPV

United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI); National Institute of Dental and Craniofacial...

Active, not recruiting

Intensity-Modulated Proton Beam Therapy or Intensity-Modulated Photon Therapy in Treating Patients With Stage III-IVB Oropharyngeal Cancer

Stage IVA Oropharyngeal Squamous Cell Carcinoma AJCC v7 | Stage IVB Oropharyngeal Squamous Cell Carcinoma AJCC v7 | Stage III Oropharyngeal Squamous Cell Carcinoma AJCC v7

United States
AstraZeneca
British Columbia Cancer Agency

Completed

Phase II Study of AZD2281 in Patients With Known BRCA Mutation Status or Recurrent High Grade Ovarian Cancer or Patients With Known BRCA Mutation Status/ Triple Neg Breast Cancer

Breast Cancer | Ovarian Carcinoma

Canada
Washington University School of Medicine
The Foundation for Barnes-Jewish Hospital; American College of Chest Physicians

Completed

Early Warning System

Diabetes Mellitus | Cancer | Chronic Obstructive Pulmonary Disease | Obstructive Sleep Apnea | Congestive Heart Failure

United States
Applied Biology, Inc.

Completed

Anti-Androgen Treatment for COVID-19

COVID-19 | Benign Prostatic Hyperplasia | Prostate Cancer | SARS-CoV2 | Androgenetic Alopecia | SARS (Severe Acute Respiratory Syndrome)

Brazil
Washington University School of Medicine

Unknown

How Microbes and Metabolism May Predict Skin Cancer Immunotherapy Outcomes (MINING)

Melanoma | Skin Cancer | Merkel Cell Carcinoma | Basal Cell Carcinoma | Squamous Cell Carcinoma of the Skin | Autoimmunity

United States
National Cancer Institute (NCI)

Completed

A Study of Molecular and Genetic Factors for Liver Cancer in the Greater Baltimore Area

Hepatitis, Viral, Human | Carcinoma, Hepatocellular | Hepatitis, Chronic | Hepatitis, Alcoholic | Liver Cirrhosis, Alcoholic

United States

Clinical Trials on Hereditary Cancer

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