Clinical Trials on Hot Weather; Adverse Effect

Total 1313 results

Singapore National Eye Centre
National Medical Research Council (NMRC), Singapore; Singapore Eye Research... and other collaborators

Completed

Autologous ex Vivo Conjunctival Epithelial Cell Expansion for Ocular Surface Transplantation

Pterygium | Ocular Surface Disease | Chemical Injury | Stevens Johnson Syndrome

Singapore
Johns Hopkins University
National Institute on Deafness and Other Communication Disorders (NIDCD); Labyrinth...

Active, not recruiting

Multichannel Vestibular Implant Early Feasibility Study

Labyrinth Diseases | Vestibular Diseases | Sensation Disorders | Other Disorders of Vestibular Function, Bilateral | Bilateral Vestibular Deficiency (BVD) | Gentamicin Ototoxicity

United States
Children's Cancer Hospital Egypt 57357

Completed

Prevention of Chemotherapy Induced Cardiotoxicity in Children With Bone Tumors and Acute Myeloid Leukemia

Cardiotoxicity | Bone Tumor | Acute Myeloid Leukemia in Children

Egypt
European Organisation for Research and Treatment...
Ipsen

Withdrawn

Lanreotide Combined With Telotristat Ethyl or Placebo for the First-line Treatment in Patients With Advanced Well Differentiated Small Intestinal Neuroendocrine Tumours (siNET) With Highly-functioning Carcinoid Syndrome (TELEFIRST)

Small Intestinal NET | Carcinoid Heart Disease
Federal University of Mato Grosso

Completed

Safety of Gastric Volume Emptying After the Intake of Maltodextrin and Glutamine

Pulmonary Aspiration of Gastric Contents | Adverse Effects in the Therapeutic Use of Other and Unspecified General Anaesthetics | Pulmonary Aspiration During Anaesthetic Induction

Brazil
University of North Carolina, Charlotte
Teva Branded Pharmaceutical Products R&D, Inc.

Completed

Herbal Therapy for Subcutaneous Injection Site Reactions in Multiple Sclerosis (MSSkin)

Multiple Sclerosis

United States
Johns Hopkins University
National Institute on Aging (NIA); Labyrinth Devices, LLC

Recruiting

Vestibular Implantation in Older Adults

Labyrinth Diseases | Vestibular Diseases | Sensation Disorders | Bilateral Vestibulopathy | Other Disorders of Vestibular Function, Bilateral | Bilateral Vestibular Deficiency (BVD) | Gentamicin Ototoxicity | Bilateral Vestibular Hypofunction | Aminoglycoside Ototoxicity | Presbyvestibulopathy

United States
Johns Hopkins University
National Institute on Deafness and Other Communication Disorders (NIDCD); Labyrinth...

Recruiting

Vestibular Implantation to Treat Adult-Onset Bilateral Vestibular Hypofunction

Labyrinth Diseases | Vestibular Diseases | Sensation Disorders | Bilateral Vestibulopathy | Other Disorders of Vestibular Function, Bilateral | Bilateral Vestibular Deficiency (BVD) | Gentamicin Ototoxicity | Bilateral Vestibular Hypofunction | Aminoglycoside Ototoxicity

United States
Sechenov University
Pirogov Russian National Research Medical University

Recruiting

Human Leukocyte Antigen Class II (DRB1 and DQB1) Alleles and Haplotypes Frequencies in Patients With Pemphigus Vulgaris Among the Russian Population

Bullous Pemphigoid | Stevens-Johnson Syndrome | Toxic Epidermal Necrolyses | Pemphigus

Russian Federation
Sun Yat-sen University

Completed

Preventive Effect of Celecoxib on Sorafenib-related Hand Foot Syndrome, a Single Center, Randomized Controlled Clinical Trail

Hepatocellular Carcinoma
Daniel Rushing

Completed

Strain Echocardiography to Predict Cardiotoxicity in Patients Receiving Chemotherapy Containing Doxorubicin

Sarcoma | Lymphoma | Breast Neoplasms

United States
West Virginia University

Terminated

Eniluracil Hand Foot Syndrome

Breast Cancer | Colon Cancer

United States
Sound Pharmaceuticals, Incorporated
VA Puget Sound Health Care System

Unknown

SPI-1005 for Prevention and Treatment of Chemotherapy Induced Hearing Loss

Head and Neck Cancer | Lung Cancer | Hearing Loss | Ototoxicity | Tinnitus | Neuropathy

United States
Medical College of Wisconsin
The Cleveland Clinic

Not yet recruiting

PAtient Similarity for Decision-Making in Prevention of Cardiovascular Toxicity (PACT): A Feasibility Study

Ischemia | Coronary Artery Disease | Heart Failure | Hypertension | Diabetes Mellitus | Cardiomyopathies | Peripheral Artery Disease | Cardiotoxicity

United States
Assistance Publique - Hôpitaux de Paris

Not yet recruiting

LYell SYndrome MEsenchymal Stromal Cells Treatment (LYSYME)

Mesenchymal Stromal Cells | Lyell Syndrome | Overlap Syndrome | Toxic Epidermal Necrolysis | Epidermal Necrolysis | Adipose Derived Stromal Cells
Montreal Heart Institute
AstraZeneca

Recruiting

Identification and Evaluation of Patients at Risk of Developing Cardiotoxicity After Receiving Chemotherapy for Breast Cancer, Lymphoma or Leukemia (CarChem)

Lymphoma | Leukemia | Breast Cancer

Canada
University of Nebraska
National Cancer Institute (NCI)

Completed

Cardiac Magnetic Resonance Imaging in Patients With Non-Hodgkin Lymphoma or Hodgkin Lymphoma Receiving Doxorubicin

Lymphoma | Cardiac Toxicity | Chemotherapeutic Agent Toxicity

United States
Second Affiliated Hospital, School of Medicine,...

Unknown

Evaluation of Myocardial Injury After Anthracycline Chemotherapy in Osteosarcoma Patients Using CMR

Myocardial Injury | Osteosarcoma | Cardiotoxicity | Doxorubicin Induced Cardiomyopathy | Chemotherapy Induced Systolic Dysfunction

China
Massachusetts Eye and Ear Infirmary

Withdrawn

Infliximab to Improve Retention of the Boston Keratoprosthesis in Patients After Stevens Johnson Syndrome/ Toxic Epidermal Necrolysis (SJS/TENS)

Stevens-Johnson Syndrome | Corneal Blindness

United States
European Organisation for Research and Treatment...

Not yet recruiting

Improvement of Quality of Life Through Supportive Treatments for Hormone Therapy - Related Symptoms in Women With Early Breast Cancer; A Pragmatic Randomized Controlled Trial

Musculoskeletal Pain | Drug-Related Side Effects and Adverse Reactions | Breast Cancer Stage I | Breast Cancer Stage II | Breast Cancer Stage III | HER2-negative Breast Cancer | ER+ Breast Cancer
Qilu Hospital of Shandong University

Recruiting

Cardiac Toxicity and Prognostic Value of New Echocardiographic Indicators in the Treatment of Primary Multiple Myeloma

Multiple Myeloma

China
Tanta University

Recruiting

Possible Protective Effect of Celecoxib Against Capecitabine Induced Hand and Foot Syndrome in Patients With Colorectal Cancer (HFS)

Colorectal Cancer | Hand and Foot Syndrome | Erythrodysesthesia Syndrome | HFS

Egypt
Odense University Hospital

Recruiting

COr Loco-regional Advanced Lung Cancer Treated With Chemo-radiotherapy (COLA) (COLA)

Radiation Toxicity | Cardiac Disease | Cardiac Toxicity | Lung Cancer Stage III | Lung Cancer Stage II

Denmark
Massachusetts Eye and Ear Infirmary

Recruiting

Meibomian Gland Probing in the Sub-Acute Phase of Patients With Stevens-Johnson Syndrome/Toxic Epidermal Necrolysis

Dry Eye | Stevens-Johnson Syndrome | Meibomian Gland Dysfunction | Ocular Surface Disease | Toxic Epidermal Necrolyses | Meibomitis

United States
SWOG Cancer Research Network
National Cancer Institute (NCI)

Recruiting

S1501 Carvedilol in Preventing Cardiac Toxicity in Patients With Metastatic HER-2-Positive Breast Cancer

Cardiotoxicity | Recurrent Breast Carcinoma | HER2/Neu Positive | Metastatic Malignant Neoplasm in the Brain | Stage IV Breast Cancer AJCC v6 and v7

United States, Korea, Republic of, Puerto Rico, Saudi Arabia
Instituto de Investigación Sanitaria de la Fundación...
Effice Servicios Para la Investigacion S.L.

Active, not recruiting

Clinical Trial to Evaluate Safety and Efficacy of Cell Therapy in Patients With Cicatricial Conjuntivitis. (CELOPHIN)

Stevens-Johnson Syndrome | Lyell Syndrome | Pemphigoid | Chronic Conjunctivitis

Spain
Arbeitsgemeinschaft medikamentoese Tumortherapie

Completed

Multicentre Study to Determine the Cardiotoxicity of R-CHOP Compared to R-COMP in Patients With Diffuse Large B-Cell Lymphoma (NHL-14)

Diffuse Large B-Cell Lymphoma

Austria
Cambridge University Hospitals NHS Foundation Trust

Unknown

Pyridoxine in Preventing Hand-Foot Syndrome in Patients Who Are Receiving Capecitabine for Advanced Colorectal Cancer or Breast Cancer

Breast Cancer | Colorectal Cancer | Palmar-plantar Erythrodysesthesia

United Kingdom
National Cancer Institute (NCI)

Terminated

Combination Chemotherapy, Surgery, and Radiation Therapy With or Without Dexrazoxane and Trastuzumab in Treating Women With Stage III or Stage IV Breast Cancer

Inflammatory Breast Cancer | Stage IV Breast Cancer | Stage IIIA Breast Cancer | Stage IIIB Breast Cancer | Cardiac Toxicity

United States
Neuroganics LLC
Ramos Injury Law Firm

Recruiting

National Vaccine Adverse Event Reporting Survey and Etiology (NVAERS)

COVID-19 | Vaccine Adverse Reaction | Vaccine Reaction | Vasculitis | Neuritis | Thrombocytopenia | Influenza | Corona Virus Infection | Blood Clot | Guillain-Barré | Vaccine or Biological Substance, Unspecified Causing Adverse Effects in Therapeutic Use | GWAS | Genetic Sequencing

United States
Chinese PLA General Hospital

Unknown

Combi-elastography Assessment of Chronic Liver Disease Multi-center Study

Hepatitis B | Non Alcoholic Fatty Liver | Drug-induced Liver Injury

China
University of Kansas Medical Center

Completed

Evaluation of MyoStrain™ in Clinical Practice

Coronary Artery Disease | Amyloidosis | Myocarditis | Sarcoidosis | Lupus | Cardiac Failure | Drug Toxicity

United States
Biogen

Completed

Effects of Vitamin K on Redness Associated With Injection Site Reactions in Participants Treated With Plegridy (VITALITY)

Relapsing-Remitting Multiple Sclerosis

Italy
Memorial Sloan Kettering Cancer Center

Recruiting

Study of Cardiopulmonary Exercise Testing in Women Who Have HER2-Positive Breast Cancer With Mild Cardiotoxicity

Breast Cancer | HER2-positive Breast Cancer | Cardiotoxicity | Breast Cancer Stage IV | Breast Cancer Stage I | Breast Cancer Stage II | Breast Cancer Stage III | HER2-positive Metastatic Breast Cancer

United States
Merck Sharp & Dohme LLC

Terminated

Study of Preladenant for the Treatment of Antipsychotic Induced Movement Disorders in Participants With Schizophrenia (Study P04628)

Parkinsonian Disorders | Dyskinesia, Drug-Induced | Akathisia, Drug-Induced
Federal University of São Paulo

Completed

Salivary Gland Transplantation in the Treatment of Dry Eye in Patients With Stevens-Johnson Syndrome.

Dry Eye | Transplantation | Ocular Surface Disease | Symblepharon

Brazil
Children's Oncology Group
National Cancer Institute (NCI)

Completed

Combination Chemotherapy Plus Amifostine in Treating Children With Malignant Germ Cell Tumors

Ovarian Cancer | Extragonadal Germ Cell Tumor | Childhood Germ Cell Tumor | Drug/Agent Toxicity by Tissue/Organ

United States, Canada, Netherlands, Puerto Rico, Switzerland, Australia
Children's Oncology Group
National Cancer Institute (NCI)

Completed

Combination Chemotherapy in Treating Patients With Acute Lymphoblastic Leukemia or Advanced Lymphoblastic Non-Hodgkin's Lymphoma (T-Cell #4)

Lymphoma | Leukemia | Cardiac Toxicity
University of Rochester

Completed

Antithymocyte Globulin and Sirolimus in Treating Patients With Relapsed Multiple Myeloma

Multiple Myeloma and Plasma Cell Neoplasm | Drug/Agent Toxicity by Tissue/Organ

United States
Brigham and Women's Hospital
National Institute of Allergy and Infectious Diseases (NIAID)

Recruiting

Mechanisms of Benefit of IL4RA Inhibition in Aspirin-Exacerbated Respiratory Disease (MARINER)

Nasal Polyps | Aspirin-Sensitive Asthma With Nasal Polyps | Asthma, Aspirin-Induced | Aspirin-Exacerbated Respiratory Disease

United States
Queen Mary University of London
Royal Free Hospital NHS Foundation Trust

Active, not recruiting

Investigation of a Transcatheter Tricuspid Valved Stent Graft in Patients With Carcinoid Heart Disease (TRICAR)

Carcinoid Syndrome | Carcinoid Heart Disease | Tricuspid Regurgitation | Tricuspid Valve Disease

United Kingdom
Brigham and Women's Hospital

Completed

Therapeutic Control of Aspirin-Exacerbated Respiratory Disease With Ifetroban

Nasal Polyps | Aspirin-exacerbated Respiratory Disease | Aspirin-Sensitive Asthma With Nasal Polyps | Asthma, Aspirin-Induced

United States
University Hospital Inselspital, Berne
University of Bern; Spital STS AG; Bürgerspital Solothurn; Lindenhofspital

Terminated

Cancer Adverse Effects PReventIon With Care & Exercise: the CAPRICE Study

Lymphoma | Physical Activity | Breast Neoplasm Female | Cardiotoxicity | Anthracyclines

Switzerland
Radiation Therapy Oncology Group
National Cancer Institute (NCI)

Completed

Octreotide in Preventing or Reducing Diarrhea in Patients Receiving Chemoradiotherapy for Anal or Rectal Cancer

Colorectal Cancer | Anal Cancer | Drug/Agent Toxicity by Tissue/Organ | Radiation Enteritis

United States
Mahidol University

Unknown

Corneal Epitheliotropic Factors in Autologous Serum Eye Drops in Nonautoimmune and Stevens-Johnson Syndrome With Dry Eye

Stevens-Johnson Syndrome

Thailand
Affiliated Hospital of Qinghai University

Not yet recruiting

Cardiotoxicity of Targeted Therapy for HER-2 Positive Breast Cancer Patients at High Altitude

HER2-positive Breast Cancer | Targeted Therapy | Cardiac Toxicity | High Altitude

China
Assistance Publique - Hôpitaux de Paris

Recruiting

Drug Reactions Sampling (COLLECTIONTOXIDERMIES)

Erythema Multiforme | Stevens-Johnson Syndrome | Lyell Syndrome | Drug Reactions | AGEP | DRESS | Bullous Dermatosis Caused by Drug Treatment (Disorder) | Maculopapular Exanthem

France
Seoul National University Hospital
Ministry of Food and Drug Safety, Korea

Unknown

HLA-B*5801 Screening to Prevent Allopurinol-induced Severe Cutaneous Adverse Reaction

Kidney Failure, Chronic | Stevens-Johnson Syndrome

Korea, Republic of
AHS Cancer Control Alberta
Cross Cancer Institute

Completed

A Prospective Study of Acute Cardiovascular Effects of First-line Sunitinib in Metastatic Renal Cell Carcinoma Patients (SUnitinib Prospective CardiovasculaR Effect) (SUPER)

Heart Failure | Renal Cell Carcinoma | Hypertension | Cardiotoxicity

Canada
Merck Sharp & Dohme LLC

Completed

Caelyx in Ovarian Cancer: Prevention and Treatment of Infusion Reactions and Palmar-plantar Erythrodysesthesia (Study P04085)(COMPLETED)

Ovarian Neoplasms

Clinical Trials on Hot Weather; Adverse Effect

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Medical Conditions

Drug Interventions

CROs by country

CROs in Israel

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Rare Diseases

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