Clinical Trials on Immunologic Disease

Total 382285 results

Linkoeping University

Completed

Threatened Preterm Birth and Time of Subsequent Delivery -a Prediction Model

Preterm Birth | Immunologic Activity Alteration
University of California, Los Angeles
Jeffrey Modell Foundation

Unknown

Improving the Diagnosis of Common Variable Immune Deficiency

CVI - Common Variable Immunodeficiency

United States
Hopital Foch
Siemens Healthcare QT

Recruiting

A Prospective Monocentric Study to Assess the Concordance of Lung MRI Compared to Chest CT Scan to Assess the Extent and Severity of Bronchial and Parenchymal Pulmonary Lesions in Adult Patients With Primary Immune Deficiency (PID) . (IRMvsSCANNER)

Primary Immune Deficiency

France
Green Cross Corporation
Atlantic Research Group

Recruiting

Study of Immune Globulin Intravenous (Human) GC5107 in Pediatric Subjects With Primary Humoral Immunodeficiency

Primary Immune Deficiency

United States
Imagine Institute
Assistance Publique - Hôpitaux de Paris

Completed

Evaluation of the Efficacy of the Sequencing Method by Gene-panel (Génétique-DIH)

Primary Immuno-Deficiencies

France
Shanghai Children's Medical Center

Unknown

Mutation of the BTK Gene and Genotype-phenotype Correlation of Chinese Patients With X-Linked Agammaglobulinemia

Agammaglobulinemia, BTK

China
University of South Florida

Unknown

Evaluation of Efficacy and Tolerability of Hizentra®

Primary Immunodeficiency Disorders

United States
CSL Behring

Completed

Retrospective Chart Review of Subcutaneous IgG Use in Infants

Primary Immune Deficiency

United States
Grifols Therapeutics LLC

Completed

A Study to Evaluate the Pharmacokinetics, Safety, and Tolerability of Immune Globulin (Human) 10% (Gamunex-C) PEG Process (IVIG-PEG) Compared to Gamunex-C in Participants With Primary Humoral Immunodeficiency

Primary Immunodeficiency

United States
University Hospital Center of Martinique
Laboratoire Cerba

Completed

Influence of IL28B Genetic Variation on the Phenotype Infection of HTLV-1 (HAMIL28B)

HTLV-I Infections

Martinique
National Heart, Lung, and Blood Institute (NHLBI)

Completed

T-Cell Depletion in Unrelated Donor Marrow Transplantation

Myelodysplastic Syndromes | Leukemia | Bone Marrow Transplantation | Graft vs Host Disease | Immunologic Diseases
Takeda

Recruiting

At-Home Subcutaneous Immunoglobulin Replacement Therapy Using Alexa Skill

Primary Immunodeficiency Diseases (PID)

United States
Takeda
Takeda Development Center Americas, Inc.

Recruiting

A Study About How TAK-881 is Processed by the Body and Side Effects in People With Primary Immunodeficiency Diseases

Primary Immunodeficiency Diseases (PID)

United States
Takeda

Completed

A Study of TAK-771 in Japanese People With Primary Immunodeficiency Diseases (PID)

Primary Immunodeficiency Diseases (PID)

Japan
Baxalta now part of Shire

Completed

Immune Globulin Subcutaenous (Human), 20%

Primary Immunodeficiency Diseases (PID)

Germany, Austria, Hungary, Sweden, United Kingdom
National Institute of Allergy and Infectious Diseases...

Recruiting

Immunogenicity of the 9-Valent Human Papillomavirus Recombinant Vaccine in People With Idiopathic CD4 T Cell Lymphocytopenia

Idiopathic CD4 T Cell Lymphocytopenia

United States
CSL Behring

Completed

Study of Subcutaneous Immunoglobulin in Patients With PID Requiring IgG Replacement Therapy

Primary Immune Deficiency

United States
The Cleveland Clinic

Completed

Cytomegalovirus Hyperimmune Globulin (CMV-Ig) Replacement in Hypogammaglobulinemic Lung Transplant Recipients

Hypogammaglobulinemia

United States
CES University
IPS Fundación SIAM

Unknown

Zinc Supplementation Effect on Immune Recovery in HIV Patients

HIV | AIDS | Immunological Deficiency | Inadequate Immune Recovery | Viral Replication

Colombia
National Institute of Allergy and Infectious Diseases...
NeoImmune Tech

Not yet recruiting

A Single-arm, Dose-escalation Trial of Long-acting Recombinant Human IL-7 (NT-I7, Efineptakin Alfa) for Idiopathic CD4 Lymphopenia

Idiopathic CD4 Lymphopenia

United States
National Cancer Institute (NCI)

Recruiting

Allogeneic Hematopoietic Stem Cell Transplant for GATA2 Mutations

MDS | Immunodeficiency | GATA2

United States
National Cancer Institute (NCI)

Completed

Pilot and Feasibility Study of Reduced-Intensity Hematopoietic Stem Cell Transplant for MonoMAC

MDS | Immunodeficiency | GATA2

United States
Columbia University
Grifols Therapeutics LLC

Completed

Intravenous Immunoglobulin (IVIG) in Lung Transplantation

Lung Transplantation | Hypogammaglobulinemia

United States
Takeda

Active, not recruiting

A Study to Evaluate the Long-term Safety of TAK-771 in Japanese Primary Immunodeficiency Disease (PID) Participants

Primary Immunodeficiency Diseases (PID)

Japan
Baxalta now part of Shire
Baxalta Innovations GmbH, now part of Shire

Completed

Efficacy, Safety, Tolerability, Immunogenicity and Pharmacokinetic Evaluation of HYQVIA in Pediatric PIDD Subjects

Primary Immunodeficiency Diseases (PID)

United States
Baxalta now part of Shire

Completed

Non-Interventional Post-Marketing Safety Study on the Long-Term Safety of HYQVIA (Global)

Primary Immunodeficiency Diseases (PID)

United States
Baxalta now part of Shire

Completed

Gammagard Liquid and rHuPH20 in PID

Primary Immunodeficiency Diseases (PID)

United States, Canada
Baxalta now part of Shire

Completed

Tolerability and Safety of Immune Globulin Subcutaneous Solution (IGSC) and rHuPH20 in PID

Primary Immunodeficiency Diseases (PID)

United States
TRPHARM

Enrolling by invitation

Evaluation of Adenosine Deaminase (ADA) Enzyme Deficiency in Patients With Lymphopenia and/or Elevated Immunoglobulin E

Adenosine Deaminase Deficiency

Turkey
CSL Behring

Completed

Multicenter Study of Long-Term Clinical Outcomes of Subcutaneous Immune Globulin IgPro20 in Subjects With Primary Immunodeficiency (Japan Study)

Primary Immune Deficiency

Japan
CSL Behring

Completed

Study of Subcutaneous Immune Globulin in Patients Requiring IgG Replacement Therapy (EU Extension Study)

Primary Immunodeficiency (PID)

Poland, Germany, France, Romania, Spain, Sweden, Switzerland, United Kingdom
Grifols Therapeutics LLC

Withdrawn

Study Evaluating IGSC 20% Flexible Dosing in Treatment-Experienced and Treatment-Naive Subjects With Primary Immunodeficiency

Primary Immunodeficiency

United States
Rochester General Hospital

Completed

Humoral Immunodeficiency in CLL and Therapy With Subcutaneous Ig

Secondary Immune Deficiency Disorder

United States
Sohag University

Unknown

Evaluation of Anti-neutrophil Cytoplasm Antibodies Test

Immunological Testing in Small-vessel Vasculitis

Japan
National Institute of Allergy and Infectious Diseases...

Recruiting

Detection and Characterization of Infections and Infection Susceptibility

Immune Deficiencies

United States
University Hospital, Montpellier

Recruiting

Systematic Screening for Primary Immunodeficiencies in Patients Hospitalized for Severe Infections in Intensive Care. (DIPREA)

Primary Immunodeficiency

France
National Institute of Allergy and Infectious Diseases...
National Institute of Mental Health (NIMH)

Recruiting

NIAID Centralized Sequencing Protocol

Primary Immunodeficiency | Atopy | Autoinflammation | Autoimmunity

United States
CSL Behring

Completed

Study of Subcutaneous Immune Globulin in Patients Requiring IgG Replacement Therapy (Japan Study)

Primary Immune Deficiency

Japan
CSL Behring

Completed

Extension Study of Subcutaneous Immunoglobulin Human in Patients With Primary Immunodeficiency (PID)

Primary Immune Deficiency

United States
CSL Limited

Completed

Safety Study of Subcutaneous Ig NextGen 16% in Patients With Primary Immunodeficiency

Primary Immune Deficiency

Australia, New Zealand
GlaxoSmithKline
Icahn School of Medicine at Mount Sinai

Completed

A Laboratory Evaluation of the Humoral Immune Response in Adults and Children to the H1 Hemagglutinin (HA) Stalk Domain and Other Influenza A Virus Protein Epitopes, After Administration of GlaxoSmithKline (GSK) Biologicals' Pandemic Influenza Vaccines

Immunologic Tests

United States
Enzyvant Therapeutics GmBH

Approved for marketing

Expanded Access Protocol Thymus Transplantation

Immunodeficiency | Poor Thymic Function | Athymia | Immunoreconstitution | Thymus Transplantation | Low T Cell Numbers
Tuberculosis Network European Trialsgroup

Completed

T Cell Interferon-gamma Release Assay (TIGRA) in Immunocompromised Individuals (TBNET-TIPS)

Tuberculosis | Monitoring, Immunologic

Denmark, United Kingdom, Sweden, Australia, Bulgaria, Germany, Greece, Italy, Netherlands, Portugal, Romania, Spain, Switzerland, Turkey
National Institute of Allergy and Infectious Diseases...

Completed

Immune System and Gut Abnormalities in Patients With Common Variable Immunodeficiency With and Without Gastrointestinal Symptoms

Common Variable Immunodeficiency

United States
Children's Hospital Medical Center, Cincinnati
Bristol-Myers Squibb

Recruiting

Abatacept for the Treatment of Common Variable Immunodeficiency With Interstitial Lung Disease (ABCVILD)

Common Variable Immunodeficiency | Interstitial Lung Disease

United States
Takeda
Takeda Development Center Americas, Inc.; Baxalta Innovations GmbH, now part...

Not yet recruiting

A Study About the Long-Term Safety of TAK-881 in People With Primary Immunodeficiency Diseases

Primary Immunodeficiency Diseases (PID)
Baxalta now part of Shire

Completed

A Study of Immune Globulin Subcutaneous (Human), 20% Solution (IGSC, 20%) in Japanese Participants With Primary Immunodeficiency Diseases (PID)

Primary Immunodeficiency Diseases (PID)

Japan
Baxalta now part of Shire
Baxalta Innovations GmbH, now part of Shire

Completed

Post-Authorization Safety, Tolerability and Immunogenicity Evaluation of HyQvia in Pediatric PIDD Subjects

Primary Immunodeficiency Diseases (PID)

Denmark, United Kingdom, Czechia, France, Greece, Hungary, Slovakia, Sweden
Baxalta now part of Shire

Completed

Phase 2/3 Study of IGSC, 20% in PIDD

Primary Immunodeficiency Diseases (PID)

United States, Canada
Baxalta now part of Shire

Completed

Tolerability and Safety of IGI, 10% With rHuPH20 in PIDD

Primary Immunodeficiency Diseases (PID)

United States

Clinical Trials on Immunologic Disease

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